BR112015003785A2 - vírus, vacina, teste de diagnóstico para distinguir mamíferos vacinados com uma vacina, e, uso de um teste de diagnóstico - Google Patents

vírus, vacina, teste de diagnóstico para distinguir mamíferos vacinados com uma vacina, e, uso de um teste de diagnóstico

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Publication number
BR112015003785A2
BR112015003785A2 BR112015003785A BR112015003785A BR112015003785A2 BR 112015003785 A2 BR112015003785 A2 BR 112015003785A2 BR 112015003785 A BR112015003785 A BR 112015003785A BR 112015003785 A BR112015003785 A BR 112015003785A BR 112015003785 A2 BR112015003785 A2 BR 112015003785A2
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BR
Brazil
Prior art keywords
vaccine
diagnostic test
virus
vaccinated
csfv
Prior art date
Application number
BR112015003785A
Other languages
English (en)
Inventor
Lamp Benjamin
Wentz Eveline
De Smit Hans
Tilmann Ruemenapf Hans
Original Assignee
Intervet Int Bv
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Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of BR112015003785A2 publication Critical patent/BR112015003785A2/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24321Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae
    • G01N2333/183Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/9506Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from viruses
    • G01N2333/9513Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from viruses derived from RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)

Abstract

1 / 1 resumo “vãrus, vacina, teste de diagnã“stico para distinguir mamãferos vacinados com uma vacina, e, uso de um teste de diagnã“stico” a presente invenã§ã£o refere-se ao vã­rus da diarrã©ia viral bovina, (bvdv), vã­rus da peste suã­na clã¡ssica (csfv), vã­rus da doenã§a das fronteiras dos ovinos (bdv), e pestivã­rus atã­picos competentes para replicaã§ã£o tendo uma modificaã§ã£o em um epã­topo de uma proteã­na viral, ao seu uso como um medicamento, ao seu uso como uma vacina, ã s vacinas compreendendo tais bvdv, csfv, pestivã­rus atã­picos ou bdv competentes para replicaã§ã£o e aos testes de diagnã³stico para a detecã§ã£o de anticorpos contra tais vã­rus e para distinguir animais vacinados de animais infectados nos campos.
BR112015003785A 2012-08-29 2013-08-28 vírus, vacina, teste de diagnóstico para distinguir mamíferos vacinados com uma vacina, e, uso de um teste de diagnóstico BR112015003785A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12182260 2012-08-29
PCT/EP2013/067771 WO2014033149A1 (en) 2012-08-29 2013-08-28 Marker vaccine

Publications (1)

Publication Number Publication Date
BR112015003785A2 true BR112015003785A2 (pt) 2017-08-08

Family

ID=46785273

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015003785A BR112015003785A2 (pt) 2012-08-29 2013-08-28 vírus, vacina, teste de diagnóstico para distinguir mamíferos vacinados com uma vacina, e, uso de um teste de diagnóstico

Country Status (11)

Country Link
US (1) US20150290314A1 (pt)
EP (1) EP2890707A1 (pt)
JP (1) JP2015533478A (pt)
CN (1) CN104619720A (pt)
AU (1) AU2013307310A1 (pt)
BR (1) BR112015003785A2 (pt)
MX (1) MX2015002688A (pt)
NZ (1) NZ631110A (pt)
RU (1) RU2015111179A (pt)
WO (1) WO2014033149A1 (pt)
ZA (1) ZA201500656B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104248761B (zh) * 2014-06-24 2018-02-02 普莱柯生物工程股份有限公司 一种疫苗组合物及其制备方法和应用
CN105717293B (zh) * 2014-12-03 2017-11-10 洛阳普莱柯万泰生物技术有限公司 一种用于检测猪圆环病毒2型的试剂盒
EA038831B1 (ru) * 2015-03-05 2021-10-26 Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. Маркерная система, в частности, для экспрессируемых бакуловирусом субъединичных антигенов
AU2016382839A1 (en) * 2015-12-30 2018-06-21 Intervet International B.V. Pestivirus marker vaccine
CN111575404B (zh) * 2020-05-08 2023-03-14 中国兽医药品监察所 对猪瘟野毒及其疫苗、非洲猪瘟病毒进行鉴别诊断的基因芯片以及检测方法
CN111830257B (zh) * 2020-07-17 2023-10-24 南京农业大学 一种猪源胞内劳森菌ipma抗原检测方法及其应用
CN112481220B (zh) * 2020-11-03 2021-09-14 中国农业科学院兰州兽医研究所 抗非洲猪瘟病毒解旋酶d1133l单克隆抗体、分泌该单克隆抗体的杂交瘤细胞株及应用
WO2023032008A1 (ja) * 2021-08-30 2023-03-09 日環科学株式会社 免疫賦活化製剤と当該免疫賦活製剤を含有する化粧品、食品、飼料添加物、医薬部外品
CN115975052B (zh) * 2022-12-01 2023-06-27 北京标驰泽惠生物科技有限公司 一种猪瘟病毒的融合蛋白及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ567668A (en) * 2005-12-07 2011-07-29 Pfizer Prod Inc Marked bovine viral diarrhea virus vaccines
EP2881468B1 (en) * 2006-04-21 2017-04-12 Intervet International B.V. Pestivirus species
US7862821B2 (en) * 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
WO2010031783A1 (en) * 2008-09-17 2010-03-25 Intervet International B.V. Mutant pestivirus with mutations in core gene and ns3 region

Also Published As

Publication number Publication date
CN104619720A (zh) 2015-05-13
JP2015533478A (ja) 2015-11-26
AU2013307310A1 (en) 2015-02-12
NZ631110A (en) 2015-11-27
RU2015111179A (ru) 2016-10-20
WO2014033149A1 (en) 2014-03-06
ZA201500656B (en) 2017-09-27
US20150290314A1 (en) 2015-10-15
MX2015002688A (es) 2015-05-12
EP2890707A1 (en) 2015-07-08

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