BR112014032974A2 - método para detecção, identificação e/ou quantificação de um ou mais carboidratos, uso de um oligotiofeno conjugado luminescente, e composto - Google Patents

método para detecção, identificação e/ou quantificação de um ou mais carboidratos, uso de um oligotiofeno conjugado luminescente, e composto

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Publication number
BR112014032974A2
BR112014032974A2 BR112014032974A BR112014032974A BR112014032974A2 BR 112014032974 A2 BR112014032974 A2 BR 112014032974A2 BR 112014032974 A BR112014032974 A BR 112014032974A BR 112014032974 A BR112014032974 A BR 112014032974A BR 112014032974 A2 BR112014032974 A2 BR 112014032974A2
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BR
Brazil
Prior art keywords
detecting
carbohydrates
quantifying
identifying
luminescent conjugated
Prior art date
Application number
BR112014032974A
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English (en)
Other versions
BR112014032974B1 (pt
Inventor
Richter Dahlfors Agneta
Choong Xiankeng
Original Assignee
Richter Life Science Dev Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Richter Life Science Dev Ab filed Critical Richter Life Science Dev Ab
Publication of BR112014032974A2 publication Critical patent/BR112014032974A2/pt
Publication of BR112014032974B1 publication Critical patent/BR112014032974B1/pt

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

resumo método para detecção, identificação e/ou quantificação de um ou mais carboidratos, uso de um oligotiofeno conjugado luminescente, e composto a presente invenção refere-se a um método para detecção, identificação e/ou quantificação de um ou mais carboidratos. o método compreende as etapas de colocar um objeto ou uma amostra em contato com um oligotiofeno conjugado luminescente (lco) e detectar pelo menos um sinal de detecção do oligotiofeno conjugado luminescente. a presença e/ou a identidade e/ou a quantidade de um ou mais carboidratos que está ou estão presentes no dito objeto ou na dita amostra é determinada com base no dito sinal de detecção detectado do lco. a invenção engloba métodos para detecção de carboidrato através do uso de derivados de oligotiofeno. os métodos são rápidos, fáceis e diretos e podem ser realizados em tempo real bem como in situ.
BR112014032974-5A 2012-07-02 2013-06-27 Método para detecção, identificação e/ou quantificação de um ou mais carboidratos e uso de um oligotiofeno conjugado luminescente BR112014032974B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1250751-3 2012-07-02
SE1250751A SE536793C2 (sv) 2012-07-02 2012-07-02 Detektion av kolhydrater
PCT/SE2013/050810 WO2014007730A1 (en) 2012-07-02 2013-06-27 Carbohydrate detection

Publications (2)

Publication Number Publication Date
BR112014032974A2 true BR112014032974A2 (pt) 2017-06-27
BR112014032974B1 BR112014032974B1 (pt) 2021-09-14

Family

ID=49882344

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014032974-5A BR112014032974B1 (pt) 2012-07-02 2013-06-27 Método para detecção, identificação e/ou quantificação de um ou mais carboidratos e uso de um oligotiofeno conjugado luminescente

Country Status (11)

Country Link
US (1) US9958439B2 (pt)
EP (1) EP2867673B1 (pt)
JP (1) JP6317342B2 (pt)
AU (1) AU2013285614B2 (pt)
BR (1) BR112014032974B1 (pt)
CA (1) CA2877470C (pt)
IN (1) IN2014DN10649A (pt)
NO (1) NO2867673T3 (pt)
PL (1) PL2867673T3 (pt)
SE (1) SE536793C2 (pt)
WO (1) WO2014007730A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6982319B2 (ja) * 2015-10-01 2021-12-17 リヒター ライフ サイエンス ディヴェロップメント アクチエボラグRichter Life Science Development AB 微生物ペプチドの検出
FR3050271B1 (fr) 2016-04-18 2018-04-13 Centre National De La Recherche Scientifique Procede de sequencage d'oligosaccharides
DE102016113166B4 (de) * 2016-07-18 2022-02-24 Joanneum Research Forschungsgesellschaft Mbh Verfahren zum Nachweis eines Biofilms und Mittel zum Nachweis eines Biofilms
SE543571C2 (en) * 2019-02-07 2021-03-30 Christian Strietzel Conducting redox oligomers
JP2020165847A (ja) * 2019-03-29 2020-10-08 株式会社島津製作所 食品の品質判定方法、及び、食品品質判定装置
US20230151405A1 (en) * 2020-04-15 2023-05-18 The Penn State Research Foundation Biodegradable dna-alginate conjugate for reversible protein and cell labeling and imaging

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004022325D1 (de) * 2003-10-31 2009-09-10 Immunetics Inc Der kontamination von blutplättchen mit bakterien
WO2007075595A2 (en) 2005-12-20 2007-07-05 Vertex Pharmacueticals Incorporated Biofilm assay
BRPI0920850A2 (pt) * 2008-10-17 2016-09-13 Biochromix Pharma Ab novos compostos e sua utilização
BR112012020237B1 (pt) * 2010-02-16 2020-11-10 Celluminova Ab derivado de oligotiofeno, composição para detectar células-tronco neurais, método para uso na detecção de células-tronco neurais ou células-tronco cancerosas neurais em uma amostra biológica in vitro, método para separar células-tronco neurais ou células- tronco cancerosas neurais de outro material biológico em uma amostra biológica in vitro, uso do derivado de oligotiofeno e kit
GB201020236D0 (en) * 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues

Also Published As

Publication number Publication date
US20150212076A1 (en) 2015-07-30
WO2014007730A1 (en) 2014-01-09
US9958439B2 (en) 2018-05-01
CA2877470C (en) 2022-07-19
BR112014032974B1 (pt) 2021-09-14
EP2867673B1 (en) 2017-12-06
PL2867673T3 (pl) 2018-07-31
EP2867673A1 (en) 2015-05-06
JP2015524552A (ja) 2015-08-24
JP6317342B2 (ja) 2018-04-25
AU2013285614A1 (en) 2015-01-22
IN2014DN10649A (pt) 2015-09-11
AU2013285614B2 (en) 2018-10-18
CA2877470A1 (en) 2014-01-09
SE1250751A1 (sv) 2014-01-03
EP2867673A4 (en) 2016-03-02
SE536793C2 (sv) 2014-08-19
NO2867673T3 (pt) 2018-05-05

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/06/2013, OBSERVADAS AS CONDICOES LEGAIS.