BR112014032940A2 - ésteres de carboidratos como indutores de expressão de genes - Google Patents
ésteres de carboidratos como indutores de expressão de genesInfo
- Publication number
- BR112014032940A2 BR112014032940A2 BR112014032940A BR112014032940A BR112014032940A2 BR 112014032940 A2 BR112014032940 A2 BR 112014032940A2 BR 112014032940 A BR112014032940 A BR 112014032940A BR 112014032940 A BR112014032940 A BR 112014032940A BR 112014032940 A2 BR112014032940 A2 BR 112014032940A2
- Authority
- BR
- Brazil
- Prior art keywords
- gene expression
- carbohydrate esters
- esters
- inducers
- expression inducers
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
resumo ésteres de carboidratos como indutores de expressão de genes a presente invenção proporciona novos ésteres de hidratos de carbono, em particular ésteres de dissacárido, e os métodos para a sua preparação. estes compostos têm utilidade como componentes dos meios microbianos para a indução da expressão de genes em processos de fermentação microbiana.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261673997P | 2012-07-20 | 2012-07-20 | |
US201261746120P | 2012-12-27 | 2012-12-27 | |
PCT/US2013/051147 WO2014015179A1 (en) | 2012-07-20 | 2013-07-18 | Carbohydrate esters as inducers for gene expression |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014032940A2 true BR112014032940A2 (pt) | 2017-06-27 |
Family
ID=49949255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014032940A BR112014032940A2 (pt) | 2012-07-20 | 2013-07-18 | ésteres de carboidratos como indutores de expressão de genes |
Country Status (5)
Country | Link |
---|---|
US (3) | US10059973B2 (pt) |
EP (1) | EP2875143A4 (pt) |
CN (4) | CN104471071B (pt) |
BR (1) | BR112014032940A2 (pt) |
WO (1) | WO2014015179A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014205115A2 (en) | 2013-06-19 | 2014-12-24 | The Regents Of The University Of California | Regioselective silyl exchange of per-silylated oligosaccharides |
US20180148683A1 (en) * | 2015-07-07 | 2018-05-31 | Danisco Us Inc. | Induction of gene expression using a high concentration sugar mixture |
CN107254002A (zh) * | 2017-08-01 | 2017-10-17 | 张振 | 含有肉桂基官能团的纳米纤维素及其制备方法和应用 |
CN109030815B (zh) * | 2018-06-26 | 2021-08-10 | 安徽医科大学 | 一种用于检测液相蛋白质交互作用的蛋白质芯片及其制备方法和应用 |
CN108707595B (zh) * | 2018-07-03 | 2021-07-27 | 华东理工大学 | 一种提高真菌产纤维素酶产量的方法 |
CN109651456B (zh) * | 2018-12-31 | 2020-07-28 | 京山瑞生制药有限公司 | 一种高单酯含量的蔗糖油酸酯制备方法 |
CN111172214A (zh) * | 2020-01-16 | 2020-05-19 | 广州嘉德乐生化科技有限公司 | 一种麦芽三糖酯及其制备方法和应用 |
CN114106807B (zh) * | 2020-08-27 | 2023-05-05 | 中国石油化工股份有限公司 | 一种改性槐糖脂组合物、其制备方法及应用 |
CN113151373B (zh) * | 2021-03-09 | 2023-07-04 | 武汉臻治生物科技有限公司 | 一种具有抗菌及抗肿瘤活性的蔗糖单酯的制备方法及其应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4818816A (en) | 1981-04-28 | 1989-04-04 | Choay, S.A. | Process for the organic synthesis of oligosaccharides and derivatives thereof |
DE19518982A1 (de) | 1995-05-29 | 1996-12-05 | Hoechst Ag | Neuartige Glucose- und Sophoroselipide, ein Verfahren zu deren Herstellung und deren Verwendung |
FR2735979B1 (fr) | 1995-06-28 | 1997-08-14 | Inst Francais Du Petrole | Utilisation comme substances therapeutiquement actives ou produits cosmetiques des sophorolipides, en particulier pour le traitement de la peau |
DE19749413A1 (de) | 1997-11-07 | 1999-05-12 | Hoechst Ag | Neuartige Sophoroselipide, Verfahren zu deren Herstellung und Verwendung |
TW200403321A (en) * | 2000-04-05 | 2004-03-01 | Honeywell Int Inc | Novel polymer/substrate and polymer/polymer interfaces and methods of modeling and forming same |
CN102604916A (zh) | 2002-09-10 | 2012-07-25 | 金克克国际有限公司 | 使用高浓度糖混合物诱导基因表达 |
US9012194B2 (en) * | 2004-12-22 | 2015-04-21 | Synthezyme Llc | Sophorolipids as protein inducers and inhibitors in fermentation medium |
WO2006119048A2 (en) | 2005-04-29 | 2006-11-09 | The University Of Akron | Affinity foam fractionation for collection and purification of materials |
US8148108B2 (en) * | 2007-03-30 | 2012-04-03 | The University Of Akron | Process for producing cellulase |
EP2351847B1 (en) * | 2008-10-28 | 2017-04-05 | Kaneka Corporation | Method for producing sophorose lipid |
BRPI0921438B1 (pt) * | 2008-11-03 | 2018-11-27 | Iogen Energy Corp | processos de fermentação para produção de mistura de celulase |
CN101497633B (zh) * | 2009-03-10 | 2011-04-27 | 南京师范大学 | 一种同时制备异甜菊醇和槐糖的方法 |
AU2010249500B2 (en) * | 2009-05-21 | 2016-03-24 | Basf Enzymes Llc | Phytases, nucleic acids encoding them and methods for making and using them |
JP5782439B2 (ja) * | 2009-07-24 | 2015-09-24 | リポテック, エセ.ア.Lipotec, S.A. | 筋肉収縮を抑制する化合物 |
WO2013003291A2 (en) * | 2011-06-25 | 2013-01-03 | Tom Tao Huang | Chemically modified sophorolipids and uses thereof |
-
2013
- 2013-07-18 CN CN201380037346.2A patent/CN104471071B/zh active Active
- 2013-07-18 EP EP13820206.4A patent/EP2875143A4/en not_active Withdrawn
- 2013-07-18 WO PCT/US2013/051147 patent/WO2014015179A1/en active Application Filing
- 2013-07-18 CN CN201710227094.XA patent/CN107011391B/zh active Active
- 2013-07-18 CN CN201710225917.5A patent/CN106977558B/zh active Active
- 2013-07-18 CN CN201710225915.6A patent/CN107012188B/zh active Active
- 2013-07-18 US US14/414,957 patent/US10059973B2/en active Active
- 2013-07-18 BR BR112014032940A patent/BR112014032940A2/pt not_active IP Right Cessation
-
2018
- 2018-06-27 US US16/020,429 patent/US10870873B2/en active Active
-
2020
- 2020-11-20 US US17/100,496 patent/US20210079438A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2014015179A1 (en) | 2014-01-23 |
CN106977558B (zh) | 2020-06-09 |
CN107011391A (zh) | 2017-08-04 |
CN106977558A (zh) | 2017-07-25 |
US20180327804A1 (en) | 2018-11-15 |
EP2875143A1 (en) | 2015-05-27 |
US10870873B2 (en) | 2020-12-22 |
CN104471071A (zh) | 2015-03-25 |
EP2875143A4 (en) | 2015-12-30 |
CN107011391B (zh) | 2020-05-22 |
CN107012188B (zh) | 2020-10-30 |
US10059973B2 (en) | 2018-08-28 |
US20150152462A1 (en) | 2015-06-04 |
US20210079438A1 (en) | 2021-03-18 |
CN107012188A (zh) | 2017-08-04 |
CN104471071B (zh) | 2021-05-28 |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |