BR112014032656A8 - instrumento de análise e método para a leitura de um dispositivo de coleta de fluido - Google Patents

instrumento de análise e método para a leitura de um dispositivo de coleta de fluido

Info

Publication number
BR112014032656A8
BR112014032656A8 BR112014032656A BR112014032656A BR112014032656A8 BR 112014032656 A8 BR112014032656 A8 BR 112014032656A8 BR 112014032656 A BR112014032656 A BR 112014032656A BR 112014032656 A BR112014032656 A BR 112014032656A BR 112014032656 A8 BR112014032656 A8 BR 112014032656A8
Authority
BR
Brazil
Prior art keywords
fluid collection
wall
electrochemical cell
sample
collection device
Prior art date
Application number
BR112014032656A
Other languages
English (en)
Other versions
BR112014032656B1 (pt
BR112014032656A2 (pt
Inventor
A Samproni Jennifer
Original Assignee
Siemens Healthcare Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Inc filed Critical Siemens Healthcare Diagnostics Inc
Publication of BR112014032656A2 publication Critical patent/BR112014032656A2/pt
Publication of BR112014032656A8 publication Critical patent/BR112014032656A8/pt
Publication of BR112014032656B1 publication Critical patent/BR112014032656B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/70—Assemblies comprising two or more cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4915—Blood using flow cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/492—Determining multiple analytes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49002—Electrical device making
    • Y10T29/49117—Conductor or circuit manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

dispositivo de coleta de fluido, método de fabricação, instrumento de análise, método de utilização e método para a leitura. a presente invenção refere-se a dispositivos de coleta de fluidos, instrumentos de análise e métodos para produzir e utilizar são descritos.o dispositivo de coleta de fluido é provido com um dispositivo e uma célula eletroquímica.o dispositivo tem um a primeira e uma segunda parede (42) que definem um canal microfluídico, e um amostra (20) orifício de aplicação de amostra (20) (46) que se comunica com o canal microfluídico. a primeira parede (40) e a segunda parede(42) estão espaçadas a uma distância inferior a 150 microns. a célula eletroquímica é colocada na primeira parede (40) para entrar em contato com uma amostra (20) que viaja através do canal microfluídico. a célula eletroquímica compreendendo os receptores de moléculas de tal forma que uma propriedade física da primeira célula eletroquímica (32) é realizada mediante um ou mais dos receptores de moléculas que se ligam a uma espécie de eletroativos dentro da amostra (20).
BR112014032656-8A 2012-06-28 2013-06-27 Instrumento de análise e método para a leitura de um dispositivo de coleta de fluido BR112014032656B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261665353P 2012-06-28 2012-06-28
US61/665,353 2012-06-28
PCT/US2013/048108 WO2014004781A2 (en) 2012-06-28 2013-06-27 Reader device and method of signal amplification

Publications (3)

Publication Number Publication Date
BR112014032656A2 BR112014032656A2 (pt) 2017-06-27
BR112014032656A8 true BR112014032656A8 (pt) 2020-10-13
BR112014032656B1 BR112014032656B1 (pt) 2021-12-21

Family

ID=49784017

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014032656-8A BR112014032656B1 (pt) 2012-06-28 2013-06-27 Instrumento de análise e método para a leitura de um dispositivo de coleta de fluido

Country Status (11)

Country Link
US (3) US20150176143A1 (pt)
EP (2) EP2867660A4 (pt)
JP (1) JP5781256B2 (pt)
KR (1) KR101563486B1 (pt)
CN (1) CN104380091B (pt)
AU (1) AU2013280268B2 (pt)
BR (1) BR112014032656B1 (pt)
CA (1) CA2877888C (pt)
MX (2) MX367230B (pt)
RU (2) RU2015102604A (pt)
WO (1) WO2014004781A2 (pt)

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* Cited by examiner, † Cited by third party
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TWM467058U (zh) * 2013-05-10 2013-12-01 Rapha Bio Ltd 生化感測器
KR101582098B1 (ko) * 2015-09-08 2016-01-04 대윤계기산업주식회사 전자기 유도식 전기전도도 센서를 이용한 고농도 액체 측정기
JP6988761B2 (ja) 2018-10-11 2022-01-05 信越半導体株式会社 半導体シリコンウェーハの洗浄処理装置および洗浄方法

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Also Published As

Publication number Publication date
EP2867660A2 (en) 2015-05-06
CN104380091B (zh) 2016-06-22
RU2015102604A (ru) 2016-08-20
JP2015522164A (ja) 2015-08-03
EP2867660A4 (en) 2015-12-23
JP5781256B2 (ja) 2015-09-16
US20150176143A1 (en) 2015-06-25
US10921280B2 (en) 2021-02-16
US20190285568A1 (en) 2019-09-19
US10330630B2 (en) 2019-06-25
US20170168006A1 (en) 2017-06-15
AU2013280268B2 (en) 2015-02-26
MX367230B (es) 2019-08-09
RU2016128035A3 (pt) 2019-10-03
KR101563486B1 (ko) 2015-10-27
RU2016128035A (ru) 2018-12-06
KR20150023069A (ko) 2015-03-04
BR112014032656B1 (pt) 2021-12-21
CN104380091A (zh) 2015-02-25
RU2713046C2 (ru) 2020-02-03
EP3101415A1 (en) 2016-12-07
WO2014004781A2 (en) 2014-01-03
WO2014004781A3 (en) 2014-03-20
MX2014015162A (es) 2015-03-05
BR112014032656A2 (pt) 2017-06-27
CA2877888A1 (en) 2014-01-03
CA2877888C (en) 2016-02-02
AU2013280268A1 (en) 2015-02-12

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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