BR112013024190A2 - microdispositivo para detectar ou tratar doença e métodos para fabricar microdispositivo e para detectar doença em indivíduo em necessidade do mesmo - Google Patents
microdispositivo para detectar ou tratar doença e métodos para fabricar microdispositivo e para detectar doença em indivíduo em necessidade do mesmoInfo
- Publication number
- BR112013024190A2 BR112013024190A2 BR112013024190A BR112013024190A BR112013024190A2 BR 112013024190 A2 BR112013024190 A2 BR 112013024190A2 BR 112013024190 A BR112013024190 A BR 112013024190A BR 112013024190 A BR112013024190 A BR 112013024190A BR 112013024190 A2 BR112013024190 A2 BR 112013024190A2
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- Prior art keywords
- detecting
- microdevice
- disease
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- methods
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
- G01D21/00—Measuring or testing not otherwise provided for
- G01D21/02—Measuring two or more variables by means not covered by a single other subclass
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/028—Microscale sensors, e.g. electromechanical sensors [MEMS]
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0663—Stretching or orienting elongated molecules or particles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Fluid Mechanics (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Electrochemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
microdispositivo para detectar ou tratar doença e métodos para fabricar microdispositivo e para detectar doença em indivíduo em necessidade do mesmo entre outros, a presente invenção proporciona microdispositivos para detectar ou tratar uma doença, cada um compreendendo um primeiro microssensor para detectar uma propriedade da amostra biológica no nível microscópico e definido uma parede interna um canal, sendo que o microssensor está localizado na parede interna do microdispositivo e detecta a propriedade da amostra biológica no nível microscópico e amostra biológica é transportada dentro do canal.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161467097P | 2011-03-24 | 2011-03-24 | |
US201161498954P | 2011-06-20 | 2011-06-20 | |
PCT/US2011/042637 WO2012003348A2 (en) | 2010-06-30 | 2011-06-30 | Apparatus for disease detection |
PCT/US2011/054979 WO2012048040A2 (en) | 2010-10-05 | 2011-10-05 | Micro-devices for disease detection |
PCT/US2012/022921 WO2012128841A2 (en) | 2011-03-24 | 2012-01-27 | Micro-devices for disease detection |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013024190A2 true BR112013024190A2 (pt) | 2016-12-13 |
Family
ID=46879952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013024190A BR112013024190A2 (pt) | 2011-03-24 | 2012-01-27 | microdispositivo para detectar ou tratar doença e métodos para fabricar microdispositivo e para detectar doença em indivíduo em necessidade do mesmo |
Country Status (11)
Country | Link |
---|---|
US (3) | US9651542B2 (pt) |
EP (1) | EP2689254A4 (pt) |
JP (1) | JP3191355U (pt) |
KR (1) | KR20150023022A (pt) |
CN (1) | CN103562728B (pt) |
AU (1) | AU2012231737B2 (pt) |
BR (1) | BR112013024190A2 (pt) |
CA (1) | CA2831223C (pt) |
IL (1) | IL228501B (pt) |
WO (1) | WO2012128841A2 (pt) |
ZA (1) | ZA201307591B (pt) |
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KR20150023022A (ko) * | 2011-03-24 | 2015-03-04 | 앤팩 바이오-메디컬 사이언스 시오., 엘티디. | 질병 검출용 마이크로 소자 |
CN103998921B (zh) * | 2011-10-14 | 2016-04-20 | 贝克顿·迪金森公司 | 方波热循环 |
TW201319563A (zh) * | 2011-11-08 | 2013-05-16 | Jung-Tang Huang | 整合ic晶片與塑膠微流體基板的檢測系統 |
WO2014106493A1 (en) | 2013-01-07 | 2014-07-10 | Anpac Bio-Medical Science (Lishui) Co., Ltd. | Apparatus for improved disease detection |
CN105705088A (zh) * | 2013-03-15 | 2016-06-22 | 安派科生物医学科技(丽水)有限公司 | 增强型疾病检测仪器及方法 |
CN103810400A (zh) * | 2014-03-12 | 2014-05-21 | 大连民族学院 | 一种人体部分慢性疾病预警系统和预警方法 |
US9706269B2 (en) * | 2015-07-24 | 2017-07-11 | Hong Kong Applied Science and Technology Research Institute Company, Limited | Self-powered and battery-assisted CMOS wireless bio-sensing IC platform |
US10379131B2 (en) | 2015-11-18 | 2019-08-13 | Elbit Systems Of America/Kmc Systems, Inc. | Systems and methods for detecting a liquid level |
AU2017234382B2 (en) * | 2016-03-18 | 2022-03-10 | La Trobe University | Mobile voltammetric analysis |
CN109844092A (zh) * | 2017-03-10 | 2019-06-04 | 上海新申派科技有限公司 | 新型的疾病检测仪和方法 |
US10641733B2 (en) * | 2017-03-20 | 2020-05-05 | National Technology & Engineering Solutions Of Sandia, Llc | Active mechanical-environmental-thermal MEMS device for nanoscale characterization |
KR101851684B1 (ko) * | 2017-12-15 | 2018-04-24 | 한국가스안전공사 | 수소제트화염 연소실험장치 및 이를 이용하는 수소제트화염 연소실험방법 |
CA3073594A1 (en) * | 2018-04-23 | 2019-10-31 | Anpac Bio-Medical Science Co., Ltd. | New apparatus and methods for disease detection |
KR102332987B1 (ko) * | 2018-07-20 | 2021-12-01 | 재단법인대구경북과학기술원 | 원심 밸브 제어 장치 |
WO2020073055A1 (en) * | 2018-10-05 | 2020-04-09 | Anpac Bio-Medical Science Co., Ltd. | New apparatus and methods for disease detection and treatment |
US10802090B2 (en) * | 2018-12-21 | 2020-10-13 | Industrial Technology Research Institute | Magnetic biosensor and method of detecting biosignal |
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CN110763280A (zh) * | 2019-11-14 | 2020-02-07 | 湖南中部芯谷科技有限公司 | 一种微电子胶管监测装置 |
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CN112165766B (zh) * | 2020-10-30 | 2021-05-04 | 哈尔滨工业大学(深圳) | 一种液态金属柔性电子及其制备方法和应用 |
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- 2012-01-27 WO PCT/US2012/022921 patent/WO2012128841A2/en active Application Filing
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- 2012-01-27 CN CN201280016082.8A patent/CN103562728B/zh active Active
- 2012-01-27 EP EP12761369.3A patent/EP2689254A4/en not_active Withdrawn
- 2012-01-27 BR BR112013024190A patent/BR112013024190A2/pt not_active Application Discontinuation
- 2012-01-27 US US14/006,805 patent/US9651542B2/en active Active
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AU2012231737A1 (en) | 2013-09-19 |
CN103562728A (zh) | 2014-02-05 |
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US20210364511A1 (en) | 2021-11-25 |
IL228501A0 (en) | 2013-12-31 |
WO2012128841A2 (en) | 2012-09-27 |
WO2012128841A3 (en) | 2012-12-06 |
KR20150023022A (ko) | 2015-03-04 |
IL228501B (en) | 2020-06-30 |
NZ706837A (en) | 2016-07-29 |
ZA201307591B (en) | 2014-12-23 |
CA2831223C (en) | 2019-04-02 |
NZ614830A (en) | 2015-10-30 |
JP3191355U (ja) | 2014-06-19 |
EP2689254A4 (en) | 2014-09-03 |
US11085923B2 (en) | 2021-08-10 |
US20170248577A1 (en) | 2017-08-31 |
AU2012231737B2 (en) | 2015-07-23 |
CN103562728B (zh) | 2016-08-17 |
CA2831223A1 (en) | 2012-09-27 |
EP2689254A2 (en) | 2014-01-29 |
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