MX367230B - Dispositivo lector y método de amplificación de señal. - Google Patents

Dispositivo lector y método de amplificación de señal.

Info

Publication number
MX367230B
MX367230B MX2016011451A MX2016011451A MX367230B MX 367230 B MX367230 B MX 367230B MX 2016011451 A MX2016011451 A MX 2016011451A MX 2016011451 A MX2016011451 A MX 2016011451A MX 367230 B MX367230 B MX 367230B
Authority
MX
Mexico
Prior art keywords
electrochemical cell
wall
microfluidic channel
sample
signal amplification
Prior art date
Application number
MX2016011451A
Other languages
English (en)
Inventor
A Samproni Jennifer
Original Assignee
Siemens Healthcare Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Inc filed Critical Siemens Healthcare Diagnostics Inc
Publication of MX367230B publication Critical patent/MX367230B/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273Devices therefor, e.g. test element readers, circuitry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/70Assemblies comprising two or more cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4915Blood using flow cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49002Electrical device making
    • Y10T29/49117Conductor or circuit manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Se divulgan dispositivos de acumulación de fluido, instrumentos de análisis y métodos para hacer y utilizar los mismos. El dispositivo de acumulación de fluido es provisto con un dispositivo y una célula electroquímica. El dispositivo tiene una primera y segunda paredes que definen un canal microfluídico, y un puerto de aplicación de muestras que comunica con el canal microfluídico. La primera pared y la segunda pared están espaciadas a una distancia menor que 150 micrómetros. La célula electroquímica se dispone en la primera pared para contactar una muestra que viaja a través del canal microfluídico. La célula electroquímica que comprende receptores moleculares de tal forma que se afecta una propiedad física de la primera célula electroquímica con uno o más de los receptores moleculares que se unen a una especie electroactiva en la muestra.
MX2016011451A 2012-06-28 2013-06-27 Dispositivo lector y método de amplificación de señal. MX367230B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261665353P 2012-06-28 2012-06-28
PCT/US2013/048108 WO2014004781A2 (en) 2012-06-28 2013-06-27 Reader device and method of signal amplification

Publications (1)

Publication Number Publication Date
MX367230B true MX367230B (es) 2019-08-09

Family

ID=49784017

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016011451A MX367230B (es) 2012-06-28 2013-06-27 Dispositivo lector y método de amplificación de señal.
MX2014015162A MX2014015162A (es) 2012-06-28 2013-06-27 Dispositivo lector y metodo de amplificacion de señal.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2014015162A MX2014015162A (es) 2012-06-28 2013-06-27 Dispositivo lector y metodo de amplificacion de señal.

Country Status (11)

Country Link
US (3) US20150176143A1 (es)
EP (2) EP2867660A4 (es)
JP (1) JP5781256B2 (es)
KR (1) KR101563486B1 (es)
CN (1) CN104380091B (es)
AU (1) AU2013280268B2 (es)
BR (1) BR112014032656B1 (es)
CA (1) CA2877888C (es)
MX (2) MX367230B (es)
RU (2) RU2015102604A (es)
WO (1) WO2014004781A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWM467058U (zh) * 2013-05-10 2013-12-01 Rapha Bio Ltd 生化感測器
KR101582098B1 (ko) * 2015-09-08 2016-01-04 대윤계기산업주식회사 전자기 유도식 전기전도도 센서를 이용한 고농도 액체 측정기
JP6988761B2 (ja) 2018-10-11 2022-01-05 信越半導体株式会社 半導体シリコンウェーハの洗浄処理装置および洗浄方法

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Also Published As

Publication number Publication date
EP2867660A2 (en) 2015-05-06
CN104380091B (zh) 2016-06-22
RU2015102604A (ru) 2016-08-20
JP2015522164A (ja) 2015-08-03
EP2867660A4 (en) 2015-12-23
JP5781256B2 (ja) 2015-09-16
US20150176143A1 (en) 2015-06-25
US10921280B2 (en) 2021-02-16
US20190285568A1 (en) 2019-09-19
US10330630B2 (en) 2019-06-25
US20170168006A1 (en) 2017-06-15
AU2013280268B2 (en) 2015-02-26
BR112014032656A8 (pt) 2020-10-13
RU2016128035A3 (es) 2019-10-03
KR101563486B1 (ko) 2015-10-27
RU2016128035A (ru) 2018-12-06
KR20150023069A (ko) 2015-03-04
BR112014032656B1 (pt) 2021-12-21
CN104380091A (zh) 2015-02-25
RU2713046C2 (ru) 2020-02-03
EP3101415A1 (en) 2016-12-07
WO2014004781A2 (en) 2014-01-03
WO2014004781A3 (en) 2014-03-20
MX2014015162A (es) 2015-03-05
BR112014032656A2 (pt) 2017-06-27
CA2877888A1 (en) 2014-01-03
CA2877888C (en) 2016-02-02
AU2013280268A1 (en) 2015-02-12

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