MX368673B - Dispositivos, sistemas y métodos para preparar muestras. - Google Patents
Dispositivos, sistemas y métodos para preparar muestras.Info
- Publication number
- MX368673B MX368673B MX2017008763A MX2017008763A MX368673B MX 368673 B MX368673 B MX 368673B MX 2017008763 A MX2017008763 A MX 2017008763A MX 2017008763 A MX2017008763 A MX 2017008763A MX 368673 B MX368673 B MX 368673B
- Authority
- MX
- Mexico
- Prior art keywords
- devices
- systems
- sonicator
- sample
- methods
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5082—Test tubes per se
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
- B01F31/86—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with vibration of the receptacle or part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
- G01N2001/4094—Concentrating samples by other techniques involving separation of suspended solids using ultrasound
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00524—Mixing by agitating sample carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
- G01N2035/00554—Mixing by a special element, e.g. stirrer using ultrasound
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Clinical Laboratory Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
Se proporcionan dispositivos, sistemas y métodos que incluyen un sonicador para preparar muestras. Un sonicador puede ser usado para mezclar, resuspender, aerosolizar, dispersar, desintegrar, o desgasificar una solución. Un sonicador puede ser usado para romper una célula, como una célula patógena en una muestra. La preparación de la muestra puede incluir exponer material que identifica al patógeno por sonicación para detectar, identificar, o medir los patógenos. Un sonicador puede transferir energía ultrasónica a la solución de muestra poniendo en contacto su punta con una pared exterior de un recipiente que contiene la muestra. Los dispositivos para propósitos múltiples incluyendo un sonicador también incluyen componentes adicionales para acciones y ensayos adicionales. Los dispositivos y sistemas que comprenden esos dispositivos, pueden comunicarse con un laboratorio u otros dispositivos en un sistema para ensayar y analizar muestras. Se proporcionan los métodos que utilizan esos dispositivos y sistemas. Los dispositivos, sistemas y métodos de preparación de muestras mejorados son útiles para analizar muestras, por ejemplo para diagnosticar pacientes que padecen de infecciones por patógenos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361799533P | 2013-03-15 | 2013-03-15 | |
| US201361806809P | 2013-03-29 | 2013-03-29 | |
| PCT/US2014/022847 WO2014150290A1 (en) | 2013-03-15 | 2014-03-10 | Devices, systems and methods for sample preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX368673B true MX368673B (es) | 2019-10-10 |
Family
ID=51580735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015011773A MX348826B (es) | 2013-03-15 | 2014-03-10 | Dispositivos, sistemas y métodos para preparar muestras. |
| MX2017008763A MX368673B (es) | 2013-03-15 | 2014-03-10 | Dispositivos, sistemas y métodos para preparar muestras. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015011773A MX348826B (es) | 2013-03-15 | 2014-03-10 | Dispositivos, sistemas y métodos para preparar muestras. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9885729B2 (es) |
| EP (2) | EP3974842A1 (es) |
| JP (3) | JP2016517516A (es) |
| KR (1) | KR20150130387A (es) |
| CN (2) | CN111366434A (es) |
| AU (1) | AU2014237362A1 (es) |
| BR (1) | BR112015022167A2 (es) |
| CA (1) | CA2906484A1 (es) |
| HK (1) | HK1219535A1 (es) |
| IL (1) | IL241429A (es) |
| MX (2) | MX348826B (es) |
| SG (1) | SG11201507322UA (es) |
| WO (1) | WO2014150290A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9359632B2 (en) | 2013-03-15 | 2016-06-07 | Theranos, Inc. | Devices, systems and methods for sample preparation |
| CN104263718B (zh) | 2014-09-26 | 2017-11-24 | 广东体必康生物科技有限公司 | 一种超声波微生物分散方法及装置 |
| FR3036799A1 (fr) * | 2015-05-28 | 2016-12-02 | Biomerieux Sa | Dispositif pour la preparation d'echantillons biologiques |
| CN106483007B (zh) * | 2015-08-24 | 2020-11-03 | 深圳迈瑞生物医疗电子股份有限公司 | 混匀器及使用该混匀器的混匀装置 |
| CN105571930B (zh) * | 2016-01-19 | 2019-05-07 | 广州迪澳生物科技有限公司 | 一种痰液自动液化仪及其痰液液化方法 |
| FR3049061B1 (fr) * | 2016-03-21 | 2018-04-20 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Dispositif d'analyse d'un echantillon biologique |
| WO2019017291A1 (ja) * | 2017-07-19 | 2019-01-24 | 平田機工株式会社 | 標本作製方法および標本作製装置 |
| WO2019064289A1 (en) * | 2017-09-29 | 2019-04-04 | Miraplex Diagnostics | TEST PREPARATION DEVICE |
| EP3549664A1 (en) | 2018-04-05 | 2019-10-09 | F. Hoffmann-La Roche AG | Method and device for sonicating a biological sample |
| EP3867635B1 (en) * | 2018-10-17 | 2026-02-18 | Hemex Health, Inc. | External sonication system |
| US11053473B2 (en) | 2019-06-25 | 2021-07-06 | Hemex Health, Inc. | External sonication |
| JP7343612B2 (ja) * | 2019-12-23 | 2023-09-12 | 株式会社日立ハイテク | 自動分析装置 |
| CN113122439A (zh) * | 2021-05-08 | 2021-07-16 | 王琼 | 用于真菌破壁提取蛋白和核酸的装置及应用该装置辅助提取蛋白和核酸的方法 |
| US20230110090A1 (en) * | 2021-10-08 | 2023-04-13 | Life Technologies Holdings Pte Limited | System and Method of Electroporation Protocol Optimization |
| CN114778866A (zh) * | 2022-04-27 | 2022-07-22 | 深圳大学 | 一种自动化检测装置 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3734805A (en) * | 1971-07-27 | 1973-05-22 | Branson Instr | Ultrasonic sewing machine |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4983523A (en) * | 1988-04-08 | 1991-01-08 | Gene-Trak Systems | Methods for preparing sample nucleic acids for hybridization |
| US5344395A (en) * | 1989-11-13 | 1994-09-06 | Scimed Life Systems, Inc. | Apparatus for intravascular cavitation or delivery of low frequency mechanical energy |
| US5876671A (en) | 1993-03-24 | 1999-03-02 | The Regents Of The University Of California Office Of Technology Transfer | Sonication standard laboratory module |
| JP3803399B2 (ja) * | 1994-09-09 | 2006-08-02 | 博行 川上 | 免疫測定装置 |
| ATE400358T1 (de) * | 1997-12-24 | 2008-07-15 | Cepheid | Vorrichtung und verfahren zur lyse |
| JPH11347391A (ja) * | 1998-06-04 | 1999-12-21 | Kinsuke Yamawaki | シェイクアップマシーン及びその方法 |
| US6410278B1 (en) | 1998-11-09 | 2002-06-25 | Eiken Kagaku Kabushiki Kaisha | Process for synthesizing nucleic acid |
| US20040200909A1 (en) * | 1999-05-28 | 2004-10-14 | Cepheid | Apparatus and method for cell disruption |
| US9073053B2 (en) | 1999-05-28 | 2015-07-07 | Cepheid | Apparatus and method for cell disruption |
| US6318158B1 (en) * | 2000-03-01 | 2001-11-20 | Coulter International Corp. | Sample preparation and delivery system employing external sonicator |
| US6598466B1 (en) | 2000-10-05 | 2003-07-29 | Xerox Corporation | Method for additive adhesion force particle analysis and apparatus thereof |
| US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
| US6739531B2 (en) * | 2001-10-04 | 2004-05-25 | Cepheid | Apparatus and method for rapid disruption of cells or viruses |
| JP2004037187A (ja) * | 2002-07-02 | 2004-02-05 | Mishima Daiji | 超音波振動供与装置とその供与方法 |
| CN102759466A (zh) * | 2004-09-15 | 2012-10-31 | 英特基因有限公司 | 微流体装置 |
| US7785868B2 (en) | 2004-12-02 | 2010-08-31 | Microfluidic Systems, Inc. | Apparatus to automatically lyse a sample |
| WO2007016605A2 (en) * | 2005-08-01 | 2007-02-08 | Covaris, Inc. | An apparatus and a method for processing a sample using acoustic energy |
| US20070105214A1 (en) * | 2005-11-09 | 2007-05-10 | Irm, Llc | Automated cellular assaying systems and related components and methods |
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| US8380650B2 (en) | 2007-01-29 | 2013-02-19 | Nec Corporation | Information extraction rule making support system, information extraction rule making support method, and information extraction rule making support program |
| JP5282088B2 (ja) * | 2007-06-21 | 2013-09-04 | ジェン−プロウブ インコーポレイテッド | 処理実行に使用する機器および容器 |
| US8240213B2 (en) * | 2007-09-27 | 2012-08-14 | Sonics & Materials Inc | System and method for ultrasonic sample preparation |
| US8088593B2 (en) | 2007-10-02 | 2012-01-03 | Theranos, Inc. | Modular point-of-care devices, systems, and uses thereof |
| DE102008021000A1 (de) * | 2008-04-25 | 2009-10-29 | Qiagen Gmbh | Verfahren und Vorrichtung zum Aufschluss von biologischem Material |
| US8895240B2 (en) * | 2008-05-19 | 2014-11-25 | E I Du Pont De Nemours And Company | Method, kit and system for collecting and processing samples for DNA and RNA detection |
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| US20110318728A1 (en) | 2008-12-30 | 2011-12-29 | Huan Lac Phan | Systems, devices, methods and kits for fluid handling |
| KR20160088958A (ko) * | 2010-02-23 | 2016-07-26 | 루미넥스 코포레이션 | 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법 |
| US9476101B2 (en) * | 2010-06-07 | 2016-10-25 | Firefly Bioworks, Inc. | Scanning multifunctional particles |
| WO2012009320A2 (en) * | 2010-07-15 | 2012-01-19 | Advanced Liquid Logic, Inc. | Systems for and methods of promoting cell lysis in droplet actuators |
| US20120045786A1 (en) * | 2010-08-19 | 2012-02-23 | Stith Curtis W | Opto-fluidic microscope diagnostic system |
| EP2466291B1 (en) * | 2010-12-15 | 2013-09-11 | F. Hoffmann-La Roche AG | Cuvette for photometric measurement of small liquid volumes |
| US8435738B2 (en) | 2011-09-25 | 2013-05-07 | Theranos, Inc. | Systems and methods for multi-analysis |
| US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| US8380541B1 (en) | 2011-09-25 | 2013-02-19 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
| MX344792B (es) * | 2011-09-25 | 2017-01-06 | Theranos Inc | Sistemas y métodos para múltiples análisis. |
| US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
| AU2013292400A1 (en) | 2012-07-18 | 2015-01-29 | Theranos, Inc. | High speed, compact centrifuge for use with small sample volumes |
| US9359632B2 (en) | 2013-03-15 | 2016-06-07 | Theranos, Inc. | Devices, systems and methods for sample preparation |
-
2014
- 2014-03-10 CA CA2906484A patent/CA2906484A1/en not_active Abandoned
- 2014-03-10 AU AU2014237362A patent/AU2014237362A1/en not_active Abandoned
- 2014-03-10 CN CN202010320504.7A patent/CN111366434A/zh active Pending
- 2014-03-10 KR KR1020157027838A patent/KR20150130387A/ko not_active Withdrawn
- 2014-03-10 EP EP21181603.8A patent/EP3974842A1/en not_active Withdrawn
- 2014-03-10 MX MX2015011773A patent/MX348826B/es active IP Right Grant
- 2014-03-10 EP EP14768967.3A patent/EP2972310A4/en not_active Withdrawn
- 2014-03-10 HK HK16107548.4A patent/HK1219535A1/zh unknown
- 2014-03-10 BR BR112015022167A patent/BR112015022167A2/pt active Search and Examination
- 2014-03-10 MX MX2017008763A patent/MX368673B/es unknown
- 2014-03-10 SG SG11201507322UA patent/SG11201507322UA/en unknown
- 2014-03-10 JP JP2016501087A patent/JP2016517516A/ja active Pending
- 2014-03-10 WO PCT/US2014/022847 patent/WO2014150290A1/en not_active Ceased
- 2014-03-10 CN CN201480027228.8A patent/CN105229465A/zh active Pending
-
2015
- 2015-09-04 US US14/845,740 patent/US9885729B2/en not_active Expired - Fee Related
- 2015-09-10 IL IL241429A patent/IL241429A/en active IP Right Grant
-
2018
- 2018-01-08 US US15/865,004 patent/US20180224472A1/en not_active Abandoned
-
2019
- 2019-01-25 JP JP2019011206A patent/JP2019095457A/ja not_active Withdrawn
-
2020
- 2020-12-28 JP JP2020218470A patent/JP2021073445A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL241429A (en) | 2017-02-28 |
| AU2014237362A1 (en) | 2015-09-17 |
| EP2972310A4 (en) | 2016-12-07 |
| US20160069916A1 (en) | 2016-03-10 |
| JP2019095457A (ja) | 2019-06-20 |
| SG11201507322UA (en) | 2015-10-29 |
| EP3974842A1 (en) | 2022-03-30 |
| JP2016517516A (ja) | 2016-06-16 |
| MX2015011773A (es) | 2016-07-20 |
| BR112015022167A2 (pt) | 2017-07-18 |
| CA2906484A1 (en) | 2014-09-25 |
| KR20150130387A (ko) | 2015-11-23 |
| CN111366434A (zh) | 2020-07-03 |
| US9885729B2 (en) | 2018-02-06 |
| IL241429A0 (en) | 2015-11-30 |
| JP2021073445A (ja) | 2021-05-13 |
| US20180224472A1 (en) | 2018-08-09 |
| MX348826B (es) | 2017-06-30 |
| WO2014150290A1 (en) | 2014-09-25 |
| EP2972310A1 (en) | 2016-01-20 |
| HK1219535A1 (zh) | 2017-04-07 |
| CN105229465A (zh) | 2016-01-06 |
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