BR112015031539A2 - eletrodos com sensor simetricamente dispostos em um sensor oftálmico eletroquímico - Google Patents

eletrodos com sensor simetricamente dispostos em um sensor oftálmico eletroquímico

Info

Publication number
BR112015031539A2
BR112015031539A2 BR112015031539A BR112015031539A BR112015031539A2 BR 112015031539 A2 BR112015031539 A2 BR 112015031539A2 BR 112015031539 A BR112015031539 A BR 112015031539A BR 112015031539 A BR112015031539 A BR 112015031539A BR 112015031539 A2 BR112015031539 A2 BR 112015031539A2
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BR
Brazil
Prior art keywords
sensor
electrochemical
symmetrically arranged
ophthalmic
eye
Prior art date
Application number
BR112015031539A
Other languages
English (en)
Inventor
Etzkorn James
Liu Zenghe
Original Assignee
Google Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Google Inc filed Critical Google Inc
Publication of BR112015031539A2 publication Critical patent/BR112015031539A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/101—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the tear film
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6821—Eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4166—Systems measuring a particular property of an electrolyte
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/002—Monitoring the patient using a local or closed circuit, e.g. in a room or building

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Artificial Intelligence (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Eye Examination Apparatus (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

resumo patente de invenção para “eletrodos com sensor simetricamente dispostos em um sensor oftálmico eletroquímico” um dispositivo aplicável ao olho inclui um sensor eletroquímico incorporado a um material polimérico configurado para aplicação a uma superfície de um olho. o sensor eletroquímico inclui um eletrodo ativo, um eletrodo de referência e um reagente que reage seletivamente com um analito para gerar uma medição de sensor relacionada a uma concentração do analito em um fluido a que o dispositivo aplicável ao olho está exposto. o eletrodo ativo pode ter uma primeira borda lateral e uma segunda borda lateral. o eletrodo de referência pode ser posicionado de modo que pelo menos uma parte da primeira e da segunda borda lateral do eletrodo ativo sejam seções respectivas adjacentes do eletrodo de referência.
BR112015031539A 2013-06-17 2014-04-21 eletrodos com sensor simetricamente dispostos em um sensor oftálmico eletroquímico BR112015031539A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/919,764 US9084561B2 (en) 2013-06-17 2013-06-17 Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor
PCT/US2014/034839 WO2014204575A1 (en) 2013-06-17 2014-04-21 Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor

Publications (1)

Publication Number Publication Date
BR112015031539A2 true BR112015031539A2 (pt) 2017-07-25

Family

ID=51798289

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015031539A BR112015031539A2 (pt) 2013-06-17 2014-04-21 eletrodos com sensor simetricamente dispostos em um sensor oftálmico eletroquímico

Country Status (7)

Country Link
US (3) US9084561B2 (pt)
EP (1) EP3011322B1 (pt)
JP (2) JP6072364B2 (pt)
CN (1) CN105339783B (pt)
AU (2) AU2014281160C1 (pt)
BR (1) BR112015031539A2 (pt)
WO (1) WO2014204575A1 (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8574295B2 (en) 2012-01-17 2013-11-05 Vista Ocular, Llc Accommodating intra-ocular lens system
US10080648B2 (en) 2012-01-24 2018-09-25 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
EP3915519A1 (en) 2012-01-24 2021-12-01 The Regents of the University of Colorado, a body corporate Modular intraocular lens designs
US9364316B1 (en) 2012-01-24 2016-06-14 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
US10028824B2 (en) 2012-01-24 2018-07-24 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
US9258907B2 (en) 2012-08-09 2016-02-09 Lockheed Martin Corporation Conformal 3D non-planar multi-layer circuitry
US9696564B1 (en) * 2012-08-21 2017-07-04 Verily Life Sciences Llc Contact lens with metal portion and polymer layer having indentations
US20140088372A1 (en) * 2012-09-25 2014-03-27 Google Inc. Information processing method
US8772745B1 (en) 2013-03-14 2014-07-08 Lockheed Martin Corporation X-ray obscuration film and related techniques
US9084561B2 (en) 2013-06-17 2015-07-21 Google Inc. Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor
US9307901B1 (en) * 2013-06-28 2016-04-12 Verily Life Sciences Llc Methods for leaving a channel in a polymer layer using a cross-linked polymer plug
AU2015219461B2 (en) 2014-02-18 2019-10-31 Alcon Inc. Modular intraocular lens designs, tools and methods
KR102347669B1 (ko) * 2014-03-28 2022-01-07 에스케이이노베이션 주식회사 이중 전극쌍을 이용한 전기화학 바이오 센서
US9547335B1 (en) * 2014-03-31 2017-01-17 Google Inc. Transparent module antenna for wearable devices
US10039492B2 (en) 2014-06-13 2018-08-07 Verily Life Sciences, LLC Conditional storage
USD754861S1 (en) 2014-10-07 2016-04-26 Verily Life Sciences Llc Contact lens antenna
US10123410B2 (en) * 2014-10-10 2018-11-06 Lockheed Martin Corporation Fine line 3D non-planar conforming circuit
EP3250152A1 (en) 2015-01-30 2017-12-06 Clarvista Medical, Inc. Modular intraocular lens designs
US10732435B2 (en) * 2015-03-03 2020-08-04 Verily Life Sciences Llc Smart contact device
US10400262B2 (en) 2015-04-01 2019-09-03 The Board Of Trustees Of The University Of Illinois Analyte sensing for eye injuries and conditions
US9681829B2 (en) 2015-04-24 2017-06-20 Verily Life Sciences Llc Eye-mountable devices and structures for eye-mountable devices
US10702375B2 (en) 2015-09-18 2020-07-07 Vista Ocular, Llc Electromyographic sensing and vision modification
CA3002085A1 (en) 2015-11-04 2017-05-11 The Regents Of The University Of Colorado, A Body Corporate Modular intraocular lens designs, tools and methods
CN108463323B (zh) 2015-11-11 2020-10-13 万福克斯视觉公司 带腔可调节透镜
US11045309B2 (en) 2016-05-05 2021-06-29 The Regents Of The University Of Colorado Intraocular lens designs for improved stability
US10188284B2 (en) * 2016-08-08 2019-01-29 Verily Life Sciences Llc Tear-film sensing eye-mountable device
US10012645B2 (en) * 2016-08-24 2018-07-03 The Florida International University Board Of Trustees Rapid zika virus detection using nano-enabled electrochemical sensing system
WO2018089699A1 (en) 2016-11-11 2018-05-17 Onefocus Vision, Inc. Accommodating cavity lens shaped with photocleavable insert
US11008413B1 (en) * 2017-03-18 2021-05-18 Verily Life Sciences Llc Biocompatible materials for underlid device fabrication
US11382736B2 (en) 2017-06-27 2022-07-12 Alcon Inc. Injector, intraocular lens system, and related methods
US11143885B2 (en) * 2017-09-25 2021-10-12 Verily Life Sciences Llc Smart contact lens with antenna and sensor
WO2019116767A1 (ja) * 2017-12-15 2019-06-20 ソニー株式会社 コンタクトレンズおよび通信システム
JP7042140B2 (ja) * 2018-03-30 2022-03-25 株式会社Provigate センサチップ
US11129563B2 (en) * 2018-04-04 2021-09-28 Verily Life Sciences Llc Eye-mountable device with muscle sensor
US11083902B2 (en) * 2018-05-29 2021-08-10 International Business Machines Corporation Biosensor package
CN108693217B (zh) * 2018-08-13 2020-09-08 上海市宝山区中西医结合医院 临床眼静息电位测定系统
CN109827898B (zh) * 2019-03-29 2021-09-17 河海大学 一种金属腐蚀试验装置
NL1044117B1 (en) * 2021-08-11 2023-02-23 Mentech Innovation A sensor carrier device for personalized emotion detection
US11357620B1 (en) 2021-09-10 2022-06-14 California LASIK & Eye, Inc. Exchangeable optics and therapeutics

Family Cites Families (179)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4055378A (en) 1971-12-31 1977-10-25 Agfa-Gevaert Aktiengesellschaft Silicone contact lens with hydrophilic surface treatment
US4122942A (en) 1974-01-31 1978-10-31 Wolfson Leonard G Hydrophilic contact lens case
US4014321A (en) 1974-11-25 1977-03-29 March Wayne F Non-invasive glucose sensor system
US3958560A (en) 1974-11-25 1976-05-25 Wayne Front March Non-invasive automatic glucose sensor system
US4143949A (en) 1976-10-28 1979-03-13 Bausch & Lomb Incorporated Process for putting a hydrophilic coating on a hydrophobic contact lens
US4136250A (en) 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4153641A (en) 1977-07-25 1979-05-08 Bausch & Lomb Incorporated Polysiloxane composition and contact lens
DE2756114B1 (de) 1977-12-16 1979-05-23 Titmus Eurocon Kontaktlinsen Verfahren zur Oberflaechenbehandlung einer harten oder dehydratisierten hydrophilen Kontaktlinse
US4309085A (en) 1979-07-12 1982-01-05 Morrison Robert J Method for measuring eye features with a contact lens
US4312575A (en) 1979-09-18 1982-01-26 Peyman Gholam A Soft corneal contact lens with tightly cross-linked polymer coating and method of making same
US4401371A (en) 1979-09-24 1983-08-30 Neefe Charles W Hydrogel oxygen generator with improved fluid flow
US4555372A (en) 1981-03-23 1985-11-26 Bausch & Lomb Incorporated Rotational molding of contact lenses
US4826936A (en) 1981-12-04 1989-05-02 Polymer Technology Corp. Silicone-containing contact lens material and contact lenses made thereof
US4604479A (en) 1981-12-04 1986-08-05 Polymer Technology Corporation Silicone-containing contact lens material and contact lenses made thereof
US4463149A (en) 1982-03-29 1984-07-31 Polymer Technology Corporation Silicone-containing contact lens material and contact lenses made thereof
US4655880A (en) * 1983-08-01 1987-04-07 Case Western Reserve University Apparatus and method for sensing species, substances and substrates using oxidase
JPS60163901A (ja) 1984-02-04 1985-08-26 Japan Synthetic Rubber Co Ltd プラズマ重合処理方法
US4686267A (en) 1985-10-11 1987-08-11 Polymer Technology Corporation Fluorine containing polymeric compositions useful in contact lenses
US4996275A (en) 1985-10-11 1991-02-26 Polymer Technology Corporation Fluorine containing polymeric compositions useful in contact lenses
US4740533A (en) 1987-07-28 1988-04-26 Ciba-Geigy Corporation Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
CA1305873C (en) 1987-05-26 1992-08-04 Howel Gwynne Giles Method and means for detecting alcohol levels in humans
US5018849A (en) 1988-11-16 1991-05-28 Ciba-Geigy Corporation Colored contact lens and methods of making the same
US5326584A (en) 1989-04-24 1994-07-05 Drexel University Biocompatible, surface modified materials and method of making the same
GB8909491D0 (en) 1989-04-26 1989-06-14 Glynn Christopher J Device for real-time monitoring of human or animal bodily functions
US5070215A (en) 1989-05-02 1991-12-03 Bausch & Lomb Incorporated Novel vinyl carbonate and vinyl carbamate contact lens material monomers
US5034461A (en) 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5177168A (en) 1989-10-17 1993-01-05 Polymer Technology Corp. Polymeric compositions useful in oxygen permeable contact lenses
US5032658A (en) 1989-10-17 1991-07-16 Polymer Technology Corporation Polymeric compositions useful in oxygen permeable contact lenses
US5177165A (en) 1990-11-27 1993-01-05 Bausch & Lomb Incorporated Surface-active macromonomers
US5135297A (en) 1990-11-27 1992-08-04 Bausch & Lomb Incorporated Surface coating of polymer objects
US5219965A (en) 1990-11-27 1993-06-15 Bausch & Lomb Incorporated Surface modification of polymer objects
US5271875A (en) 1991-09-12 1993-12-21 Bausch & Lomb Incorporated Method for molding lenses
US5310779A (en) 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
US5358995A (en) 1992-05-15 1994-10-25 Bausch & Lomb Incorporated Surface wettable silicone hydrogels
US5260000A (en) 1992-08-03 1993-11-09 Bausch & Lomb Incorporated Process for making silicone containing hydrogel lenses
US5336797A (en) 1992-12-30 1994-08-09 Bausch & Lomb Incorporated Siloxane macromonomers
US5321108A (en) 1993-02-12 1994-06-14 Bausch & Lomb Incorporated Fluorosilicone hydrogels
US5346976A (en) 1993-03-29 1994-09-13 Polymer Technology Corporation Itaconate copolymeric compositions for contact lenses
US5616757A (en) 1993-04-08 1997-04-01 Bausch & Lomb Incorporated Organosilicon-containing materials useful for biomedical devices
TW253849B (pt) 1993-08-09 1995-08-11 Ciba Geigy
WO1995017689A1 (en) 1993-12-21 1995-06-29 Bausch & Lomb Incorporated Method for increasing hydrophilicity of contact lenses
US5472436A (en) 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US5585871A (en) 1995-05-26 1996-12-17 Linden; Harry Multi-function display apparatus
CA2239902C (en) 1995-12-07 2001-08-07 Bausch & Lomb, Incorporated Monomeric units useful for reducing the modulus of low water polymeric silicone compositions
CN1084335C (zh) 1995-12-07 2002-05-08 博士伦公司 用于降低硅氧烷水凝胶的模量的单体单元
US5682210A (en) 1995-12-08 1997-10-28 Weirich; John Eye contact lens video display system
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6120460A (en) 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US5708094A (en) 1996-12-17 1998-01-13 Bausch & Lomb Incorporated Polybutadiene-based compositions for contact lenses
US5981669A (en) 1997-12-29 1999-11-09 Bausch & Lomb Incorporated Silicone-containing prepolymers and low water materials
US5935155A (en) 1998-03-13 1999-08-10 John Hopkins University, School Of Medicine Visual prosthesis and method of using same
US6614408B1 (en) 1998-03-25 2003-09-02 W. Stephen G. Mann Eye-tap for electronic newsgathering, documentary video, photojournalism, and personal safety
US6131580A (en) 1998-04-17 2000-10-17 The University Of Washington Template imprinted materials by RFGD plasma deposition
BR9910345A (pt) 1998-05-05 2001-01-09 Bausch & Lomb Método para tratar a superfìcie de uma lente de contato de hidrogel de silicone e lente de contato de hidrogel de silicone
US6348507B1 (en) 1998-05-05 2002-02-19 Bausch & Lomb Incorporated Surface treatment of silicone hydrogel contact lenses
US7398119B2 (en) 1998-07-13 2008-07-08 Childrens Hospital Los Angeles Assessing blood brain barrier dynamics or identifying or measuring selected substances, including ethanol or toxins, in a subject by analyzing Raman spectrum signals
US6087941A (en) 1998-09-01 2000-07-11 Ferraz; Mark Warning device for alerting a person falling asleep
WO2000030698A1 (en) 1998-11-20 2000-06-02 University Of Connecticut Apparatus and method for control of tissue/implant interactions
US6532298B1 (en) 1998-11-25 2003-03-11 Iridian Technologies, Inc. Portable authentication device and method using iris patterns
US6550915B1 (en) 1998-12-21 2003-04-22 Bausch & Lomb Incorporated Surface treatment of fluorinated contact lens materials
US6450642B1 (en) 1999-01-12 2002-09-17 California Institute Of Technology Lenses capable of post-fabrication power modification
DE19921399C2 (de) 1999-05-07 2003-12-18 Univ Eberhard Karls Retina-Implantat
US6200626B1 (en) 1999-05-20 2001-03-13 Bausch & Lomb Incorporated Surface-treatment of silicone medical devices comprising an intermediate carbon coating and graft polymerization
US6440571B1 (en) 1999-05-20 2002-08-27 Bausch & Lomb Incorporated Surface treatment of silicone medical devices with reactive hydrophilic polymers
US6630243B2 (en) 1999-05-20 2003-10-07 Bausch & Lomb Incorporated Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating
US6213604B1 (en) 1999-05-20 2001-04-10 Bausch & Lomb Incorporated Plasma surface treatment of silicone hydrogel contact lenses with a flexible carbon coating
US6851805B2 (en) 1999-07-02 2005-02-08 E-Vision, Llc Stabilized electro-active contact lens
ATE287661T1 (de) * 1999-08-26 2005-02-15 Novartis Pharma Gmbh Augenanalytfühler
US20020007113A1 (en) 1999-08-26 2002-01-17 March Wayne Front Ocular analyte sensor
WO2001016641A1 (en) 1999-08-31 2001-03-08 Johnson & Johnson Vision Care, Inc. Rotationally stabilized contact lenses
US7276146B2 (en) 2001-11-16 2007-10-02 Roche Diagnostics Operations, Inc. Electrodes, methods, apparatuses comprising micro-electrode arrays
US6579235B1 (en) 1999-11-01 2003-06-17 The Johns Hopkins University Method for monitoring intraocular pressure using a passive intraocular pressure sensor and patient worn monitoring recorder
AU1583601A (en) 1999-11-05 2001-06-06 Bausch & Lomb Incorporated Surface treatment of non-plasma treated silicone hydrogel contact lenses
US6431705B1 (en) 1999-11-10 2002-08-13 Infoeye Eyewear heart rate monitor
US6939299B1 (en) 1999-12-13 2005-09-06 Kurt Petersen Implantable continuous intraocular pressure sensor
US7998412B2 (en) 2000-01-07 2011-08-16 Smart Holograms Limited Ophthalmic device comprising a holographic sensor
US6735328B1 (en) 2000-03-07 2004-05-11 Agilent Technologies, Inc. Personal viewing device with system for providing identification information to a connected system
US6599559B1 (en) 2000-04-03 2003-07-29 Bausch & Lomb Incorporated Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers
US6428839B1 (en) 2000-06-02 2002-08-06 Bausch & Lomb Incorporated Surface treatment of medical device
US6779888B2 (en) 2000-07-28 2004-08-24 Ocular Sciences, Inc. Contact lenses with microchannels
US6749568B2 (en) 2000-08-21 2004-06-15 Cleveland Clinic Foundation Intraocular pressure measurement system including a sensor mounted in a contact lens
EP1319037A1 (en) 2000-09-19 2003-06-18 Bausch & Lomb Incorporated Method for applying polymeric lens coating
EP1337890A1 (en) 2000-09-28 2003-08-27 Novartis Pharma GmbH Fenestrated lens for increased tear flow and method for making the same
US6885818B2 (en) 2001-07-30 2005-04-26 Hewlett-Packard Development Company, L.P. System and method for controlling electronic devices
US6570386B2 (en) 2001-07-30 2003-05-27 Hewlett-Packard Development Company, L.P. System and method for providing power to electrical devices
US20030116447A1 (en) * 2001-11-16 2003-06-26 Surridge Nigel A. Electrodes, methods, apparatuses comprising micro-electrode arrays
US20030149350A1 (en) 2002-02-05 2003-08-07 Vittorio Porciatti Glaucoma screening system and method
US20030179094A1 (en) 2002-03-08 2003-09-25 Abreu Marcio Marc Signal-to-product coupling
DK1947501T3 (da) 2002-08-09 2012-08-06 E Vision Llc Elektroaktivt kontaktlinsesystem
US7429465B2 (en) 2002-09-13 2008-09-30 Novartis Ag Process for analyzing tear fluid
US7964390B2 (en) 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
US7131945B2 (en) 2002-10-16 2006-11-07 California Institute Of Technology Optically powered and optically data-transmitting wireless intraocular pressure sensor device
US6958169B2 (en) 2002-12-17 2005-10-25 Bausch & Lomb Incorporated Surface treatment of medical device
US20040254438A1 (en) 2003-01-09 2004-12-16 The Regents Of The University Of California Implantable devices and methods for measuring intraocular, subconjunctival or subdermal pressure and/or analyte concentration
WO2004064629A1 (en) 2003-01-21 2004-08-05 Ehrfeld Miktotechnik Ag Sensor system for detecting analytes in tear fluid
US20040181172A1 (en) 2003-03-12 2004-09-16 Carney Fiona Patricia Devices for collecting analytes of interest in tears
WO2004104962A1 (en) 2003-05-26 2004-12-02 Securecom Technologies Limited A portable communications device
DE10329615A1 (de) 2003-06-23 2005-03-03 Eberhard-Karls-Universität Tübingen Universitätsklinikum Aktives Retina-Implantat mit einer Vielzahl von Bildelementen
ES2350933T3 (es) 2003-08-07 2011-01-28 Eyesense Ag Sensor oftálmico.
US7250197B2 (en) 2003-08-25 2007-07-31 Bausch & Lomb Incorporated Plasma treatment of contact lens and IOL
ATE352054T1 (de) 2003-10-03 2007-02-15 Invisia Ltd Multifocal-linse
WO2005103201A1 (en) 2004-03-31 2005-11-03 University Of Connecticut Shape memory main-chain smectic-c elastomers
GB2417083B (en) * 2004-08-13 2006-08-16 Mark Sinclair Varney An electrochemical carbon dioxide gas sensor
WO2006015315A2 (en) 2004-07-30 2006-02-09 University Of Rochester Medical Center Intraocular video system
JP4455216B2 (ja) 2004-08-06 2010-04-21 キヤノン株式会社 検出装置
KR20060044058A (ko) 2004-11-11 2006-05-16 삼성전자주식회사 투과반사를 이용한 혈중성분 측정 장치 및 방법
GB2422660C (en) 2005-01-27 2018-04-25 H Icheck Ltd Improved device for monitoring body functions
US20070121065A1 (en) 2005-03-24 2007-05-31 Cox David D Device and method for tracking eye gaze direction
TWI249772B (en) 2005-06-07 2006-02-21 Siliconware Precision Industries Co Ltd Semiconductor device for accommodating large chip, fabrication method thereof, and carrier used in the semiconductor device
US20080218696A1 (en) 2005-07-01 2008-09-11 Jose Mir Non-Invasive Monitoring System
GB0601703D0 (en) * 2006-01-27 2006-03-08 Intellitect Water Ltd Improvement To The Design And Construction Of Electrochemical Sensors
US8118752B2 (en) 2006-02-16 2012-02-21 The Board Of Trustees Of The University Of Illinois Apparatus and methods for mapping retinal function
US7384145B2 (en) 2006-02-16 2008-06-10 The Board Of Trustees Of The University Of Illinois Mapping retinal function using corneal electrode array
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
GB0604845D0 (en) 2006-03-10 2006-04-19 Ocutec Ltd Polymeric Materials
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
CA2587097A1 (en) 2006-04-12 2007-10-12 Rikke Dootjes Lens
TW200741278A (en) 2006-04-28 2007-11-01 Wei-Bin Shiu Contact lenses
WO2007136993A1 (en) 2006-05-17 2007-11-29 Mayo Foundation For Medical Education And Research Monitoring intraocular pressure
US7878650B2 (en) 2006-06-29 2011-02-01 Fritsch Michael H Contact lens materials, designs, substances, and methods
US20110274680A1 (en) 2009-10-02 2011-11-10 Mazed Mohammad A Chemical composition and its delivery for lowering the risks of alzheimer's, cardiov ascular and type-2 diabetes diseases
DE102007003341B4 (de) 2007-01-17 2018-01-04 Eyesense Ag Okularsensor und Messsystem zum Nachweis eines Analyten in einer Augenflüssigkeit
AR064985A1 (es) 2007-01-22 2009-05-06 E Vision Llc Lente electroactivo flexible
AR064986A1 (es) 2007-01-22 2009-05-06 Pixeloptics Inc Material cristalino liquido colesterico en lente electroactiva
US8215770B2 (en) 2007-02-23 2012-07-10 E-A Ophthalmics Ophthalmic dynamic aperture
WO2008109867A2 (en) 2007-03-07 2008-09-12 University Of Washington Active contact lens
US8446341B2 (en) 2007-03-07 2013-05-21 University Of Washington Contact lens with integrated light-emitting component
US8679859B2 (en) 2007-03-12 2014-03-25 State of Oregon by and through the State Board of Higher Education on behalf of Porland State University Method for functionalizing materials and devices comprising such materials
US20090015785A1 (en) 2007-06-08 2009-01-15 Blum Ronald D Adjustable correction for a variety of ambient lighting conditions
KR101535692B1 (ko) 2007-08-31 2015-07-09 노파르티스 아게 콘택트 렌즈 포장 용액
EP2217914A1 (en) 2007-11-02 2010-08-18 Edwards Lifesciences Corporation Analyte monitoring system having back-up power source for use in either transport of the system or primary power loss
US8608310B2 (en) * 2007-11-07 2013-12-17 University Of Washington Through Its Center For Commercialization Wireless powered contact lens with biosensor
US8579434B2 (en) 2007-11-07 2013-11-12 University Of Washington Through Its Center For Commercialization Free-standing two-sided device fabrication
US20090196460A1 (en) 2008-01-17 2009-08-06 Thomas Jakobs Eye tracking system and method
WO2009094587A1 (en) 2008-01-23 2009-07-30 Deering Michael F Eye mounted displays
WO2009094643A2 (en) 2008-01-26 2009-07-30 Deering Michael F Systems using eye mounted displays
TWI511869B (zh) 2008-02-20 2015-12-11 Johnson & Johnson Vision Care 激能生醫裝置
WO2009111726A2 (en) 2008-03-06 2009-09-11 The Regents Of The University Of California Measuring outlflow resistance/facility of an eye
JP2011515157A (ja) 2008-03-18 2011-05-19 ピクセルオプティクス， インコーポレイテッド 先進電気活性光学部品デバイス
US7931832B2 (en) 2008-03-31 2011-04-26 Johnson & Johnson Vision Care, Inc. Ophthalmic lens media insert
ES2330405B1 (es) 2008-06-06 2010-09-21 Consejo Superior De Investigaciones Cientificas (Csic) (45%) Lente de contacto sensora, sistema para la monitorizacion no invasiva de la presion intraocular y metodo para poner su medida.
US20100016704A1 (en) 2008-07-16 2010-01-21 Naber John F Method and system for monitoring a condition of an eye
US8142016B2 (en) 2008-09-04 2012-03-27 Innovega, Inc. Method and apparatus for constructing a contact lens with optics
US9296158B2 (en) 2008-09-22 2016-03-29 Johnson & Johnson Vision Care, Inc. Binder of energized components in an ophthalmic lens
CA2683467C (en) 2008-10-24 2016-01-26 Jin Zhang Contact lens integrated with a biosensor for detection of glucose and other components in tears
US8092013B2 (en) 2008-10-28 2012-01-10 Johnson & Johnson Vision Care, Inc. Apparatus and method for activation of components of an energized ophthalmic lens
US9375885B2 (en) 2008-10-31 2016-06-28 Johnson & Johnson Vision Care, Inc. Processor controlled ophthalmic device
US9375886B2 (en) 2008-10-31 2016-06-28 Johnson & Johnson Vision Care Inc. Ophthalmic device with embedded microcontroller
US8169006B2 (en) 2008-11-29 2012-05-01 Electronics And Telecommunications Research Institute Bio-sensor chip for detecting target material
US20120041287A1 (en) 2008-12-04 2012-02-16 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
US20100234942A1 (en) 2009-03-11 2010-09-16 Peyman Gholam A Transition lenses with virtual pupil
JP5719340B2 (ja) 2009-03-20 2015-05-20 レティーナ インプラント アーゲー 能動型網膜インプラント
CA2756351A1 (en) 2009-03-26 2010-09-30 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acti Ng For And On Behalf Of Arizona State University Integrated device for surface-contact sampling, extraction and electrochemical measurements
EP2433176B8 (en) 2009-05-17 2017-11-29 Helmut Binder Lens with variable refraction power for the human eye
US8461226B2 (en) 2009-07-24 2013-06-11 Bausch & Lomb Incorporated Contact lens
US8060560B2 (en) 2009-08-27 2011-11-15 Net Power And Light, Inc. System and method for pervasive computing
WO2011034592A1 (en) 2009-09-18 2011-03-24 University Of Akron Optical device and method for non-invasive real-time testing of blood sugar levels
JP2013505078A (ja) 2009-09-18 2013-02-14 オーソメムス， インコーポレイテッド 眼科手術のための埋込式眼科ｍｅｍｓセンサデバイスおよび方法
WO2011035228A1 (en) 2009-09-18 2011-03-24 Orthomems, Inc. Implantable mems intraocular pressure sensor devices and methods for glaucoma monitoring
US8628194B2 (en) 2009-10-13 2014-01-14 Anton Sabeta Method and system for contact lens care and compliance
BR112012016419B1 (pt) 2010-01-05 2020-12-29 Sensimed Sa dispositivo de monitoramento da pressão intraocular, kit e sistema de monitoramento da pressão intraocular
US9128281B2 (en) 2010-09-14 2015-09-08 Microsoft Technology Licensing, Llc Eyepiece with uniformly illuminated reflective display
JP5812681B2 (ja) 2010-05-19 2015-11-17 アークレイ株式会社 電気化学センサ
US20110298794A1 (en) 2010-06-08 2011-12-08 Barney Freedman Circular polarized contact lenses and methods thereof
CN103037790A (zh) 2010-06-20 2013-04-10 伊兰扎公司 具有专用集成电路的眼科装置和方法
MY186340A (en) 2010-07-30 2021-07-13 Alcon Inc Silicone hydrogel lenses with water-rich surfaces
WO2012035429A2 (en) 2010-09-13 2012-03-22 The University Of British Columbia Remotely controlled drug delivery systems
US20120238857A1 (en) 2010-09-16 2012-09-20 Orthomems, Inc. Expandable implantable pressure sensor for intraocular surgery
EP2621339B1 (en) 2010-09-29 2020-01-15 Dexcom, Inc. Advanced continuous analyte monitoring system
US9063352B2 (en) 2010-10-11 2015-06-23 The Regents Of The University Of California Telescopic contact lens
SG189301A1 (en) 2010-10-11 2013-05-31 Adlens Beacon Inc Fluid filled adjustable contact lenses
GB201017637D0 (en) 2010-10-20 2010-12-01 Univ Dundee Device for monitoring intraocular pressure
US9114004B2 (en) 2010-10-27 2015-08-25 Iridium Medical Technology Co, Ltd. Flexible artificial retina devices
EP2508935A1 (en) 2011-04-08 2012-10-10 Nxp B.V. Flexible eye insert and glucose measuring system
US8542325B2 (en) 2011-09-29 2013-09-24 Ehren Ray Burton Color changing contact lenses
US8721074B2 (en) * 2011-11-30 2014-05-13 Johnson & Johnson Vision Care, Inc. Electrical interconnects in an electronic contact lens
US8874182B2 (en) * 2013-01-15 2014-10-28 Google Inc. Encapsulated electronics
US9084561B2 (en) 2013-06-17 2015-07-21 Google Inc. Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor

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