BR112014032636A2 - Vacinas atenuadas de streptococcus suis e métodos de produção e usos das mesmas - Google Patents

Vacinas atenuadas de streptococcus suis e métodos de produção e usos das mesmas

Info

Publication number
BR112014032636A2
BR112014032636A2 BR112014032636A BR112014032636A BR112014032636A2 BR 112014032636 A2 BR112014032636 A2 BR 112014032636A2 BR 112014032636 A BR112014032636 A BR 112014032636A BR 112014032636 A BR112014032636 A BR 112014032636A BR 112014032636 A2 BR112014032636 A2 BR 112014032636A2
Authority
BR
Brazil
Prior art keywords
suis
atenuated
production methods
methods
streptococcus suis
Prior art date
Application number
BR112014032636A
Other languages
English (en)
Inventor
R Simonson Randy
F Bey Russel
Kirubakaran Lawrence Paulraj
Reddy Sirigireddy Kamesh
A Mckeown Danielle
Original Assignee
Merial Ltd
Merial Inc
Boehringer Ingelheim Animal Health Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Merial Inc, Boehringer Ingelheim Animal Health Usa Inc filed Critical Merial Ltd
Publication of BR112014032636A2 publication Critical patent/BR112014032636A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

VACINAS ATENUADAS DE STREPTOCOCCUS SUIS E MÉTODOS DE PRODUÇÃO E USOS DAS MESMAS. A presente invenção fornece cepas atenuadas de S. suis que eliciam uma resposta imunológica em animais de S. suis,composições compreendendo as referidas cepas, métodos de vacinação contra S. suis e kits para uso com tais métodos e composições. A invenção proporciona ainda novas mutações induzidas mutagenicamente em gene de S. suis, que são úteis na produção de novas cepas bacterianas atenuadas de S. Suis.
BR112014032636A 2012-06-27 2013-06-24 Vacinas atenuadas de streptococcus suis e métodos de produção e usos das mesmas BR112014032636A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261664935P 2012-06-27 2012-06-27
PCT/US2013/047282 WO2014004361A1 (en) 2012-06-27 2013-06-24 Attenuated streptococcus suis vaccines and methods of making and use thereof

Publications (1)

Publication Number Publication Date
BR112014032636A2 true BR112014032636A2 (pt) 2017-08-29

Family

ID=48782624

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014032636A BR112014032636A2 (pt) 2012-06-27 2013-06-24 Vacinas atenuadas de streptococcus suis e métodos de produção e usos das mesmas

Country Status (19)

Country Link
US (1) US9289484B2 (pt)
EP (1) EP2866828B1 (pt)
JP (1) JP6262728B2 (pt)
KR (1) KR102126096B1 (pt)
CN (1) CN104780935B (pt)
AR (1) AR091582A1 (pt)
AU (2) AU2013280718B2 (pt)
BR (1) BR112014032636A2 (pt)
CA (1) CA2877817A1 (pt)
DK (1) DK2866828T3 (pt)
EA (1) EA036764B1 (pt)
ES (1) ES2662801T3 (pt)
HK (1) HK1203834A1 (pt)
MX (1) MX365879B (pt)
MY (1) MY173796A (pt)
NZ (1) NZ703701A (pt)
PH (1) PH12014502855B1 (pt)
PL (1) PL2866828T3 (pt)
WO (1) WO2014004361A1 (pt)

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US9132183B2 (en) * 2007-03-09 2015-09-15 Newport Laboratories Modified live (JMSO strain) Haemophilus parasuis vaccine
US10280199B2 (en) 2014-02-07 2019-05-07 Phibro Animal Health Corporation Coronavirus proteins and antigens
PL3166967T3 (pl) 2014-09-14 2023-07-24 Tel Hashomer Medical Research Infrastructure And Services Ltd. Syntetyczne ligandy receptora somatostatyny
CN105348373B (zh) * 2015-11-24 2019-01-11 武汉天种畜牧股份有限公司 猪链球菌血清3型的粘附性抗原ssust3_1962及其制备方法和应用
US10279031B2 (en) 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using
EP3454893A4 (en) * 2016-05-11 2020-01-01 Phibro Animal Health Corporation COMPOSITION WITH ANTIGENS AND A MUCUTINE ADJUVAN AND METHOD FOR USE
EP3595711A1 (en) * 2017-03-15 2020-01-22 London School of Hygiene & Tropical Medicine Whole cell vaccines
BR112020002004A2 (pt) * 2017-08-03 2020-08-25 Intervet International B.V. vacina para proteção contra streptococcus suis
WO2019046691A1 (en) * 2017-08-31 2019-03-07 Merial, Inc. STREPTOCOCCUS AM VACCINES FOR THE PROTECTION AGAINST DISEASES OF REPRODUCTIVE PIGS, PIGLETS AND GROWING PIGS AND METHODS OF MAKING AND USING THEM
BR112020011593A2 (pt) * 2017-12-15 2020-12-08 Intervet International B.V. Uma vacina para proteção contra streptococcus suis
CN110327460A (zh) * 2019-06-05 2019-10-15 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 猪链球菌病-副猪嗜血杆菌病二联亚单位疫苗及制备方法
CN112694988B (zh) * 2020-12-15 2022-12-06 武汉市农业科学院 一种鸡源猪链球菌弱毒株及其应用
CN115161333B (zh) * 2022-06-23 2023-08-25 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 一种猪链球菌的反向筛选标记、含有该反向筛选标记的猪链球菌及其应用

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US3529056A (en) * 1968-05-07 1970-09-15 American Home Prod Method of producing jowl abscess vaccine
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
ES2241042T3 (es) 1996-10-11 2005-10-16 The Regents Of The University Of California Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora.
US5980912A (en) 1997-03-25 1999-11-09 Zonagen, Inc. Chitosan induced immunopotentiation
US6455323B1 (en) * 1997-07-03 2002-09-24 Pharmacia & Upjohn Company Anti-bacterial methods and materials
US6379676B2 (en) 1999-03-10 2002-04-30 Anitox Corporation Enhancing immune response in animals
CN1649829A (zh) * 2002-03-08 2005-08-03 先灵-普劳有限公司 新型氟苯尼考类抗生素
JP4500615B2 (ja) * 2004-07-14 2010-07-14 日生研株式会社 エリシペロトリックス属のその他の菌種である血清型１８由来の豚丹毒菌感染防御活性を有する新規ポリペプチドとその遺伝子および製法
JP2009538116A (ja) * 2006-02-17 2009-11-05 ノバルティス アーゲー 細菌抗原の精製
AU2010215065B2 (en) * 2009-02-20 2014-05-15 Australian Poultry Crc Pty Limited Live attenuated vaccines
KR101209964B1 (ko) * 2010-10-15 2012-12-07 주식회사 동방 돼지 다발성 장막염 예방용 백신 조성물 및 그 제조방법

Also Published As

Publication number Publication date
AU2013280718B2 (en) 2016-06-09
EA201500054A1 (ru) 2015-06-30
EA036764B1 (ru) 2020-12-17
EP2866828A1 (en) 2015-05-06
KR102126096B1 (ko) 2020-06-23
HK1203834A1 (en) 2015-11-06
EP2866828B1 (en) 2017-12-13
CN104780935B (zh) 2018-01-02
PL2866828T3 (pl) 2018-04-30
NZ703701A (en) 2016-03-31
WO2014004361A1 (en) 2014-01-03
MX365879B (es) 2019-06-18
CN104780935A (zh) 2015-07-15
DK2866828T3 (en) 2018-01-15
AU2016222520A1 (en) 2016-09-22
PH12014502855A1 (en) 2015-02-09
AU2016222520B2 (en) 2018-03-22
US20140004144A1 (en) 2014-01-02
US9289484B2 (en) 2016-03-22
AU2013280718A1 (en) 2015-02-12
AR091582A1 (es) 2015-02-11
PH12014502855B1 (en) 2015-02-09
MX2015000045A (es) 2015-03-05
MY173796A (en) 2020-02-24
JP6262728B2 (ja) 2018-01-17
CA2877817A1 (en) 2014-01-03
KR20150033692A (ko) 2015-04-01
ES2662801T3 (es) 2018-04-09
JP2015522282A (ja) 2015-08-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: MERIAL, INC. (US)

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: A61K 39/09

Ipc: C12N 1/21 (2006.01), A61K 39/09 (2006.01), A61P 37

B25A Requested transfer of rights approved

Owner name: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC. (US)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time