EP3454893A4 - A composition comprising antigens and a mucosal adjuvant and a method for using - Google Patents

A composition comprising antigens and a mucosal adjuvant and a method for using Download PDF

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Publication number
EP3454893A4
EP3454893A4 EP16901833.0A EP16901833A EP3454893A4 EP 3454893 A4 EP3454893 A4 EP 3454893A4 EP 16901833 A EP16901833 A EP 16901833A EP 3454893 A4 EP3454893 A4 EP 3454893A4
Authority
EP
European Patent Office
Prior art keywords
antigens
composition
mucosal adjuvant
mucosal
adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16901833.0A
Other languages
German (de)
French (fr)
Other versions
EP3454893A1 (en
Inventor
Grant WEAVER
Jeff KULA
Boh Chang LIN
Karen Brown
Wesley W. JOHNSON
Michael Dennis MURPHY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phibro Animal Health Corp
Original Assignee
Phibro Animal Health Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phibro Animal Health Corp filed Critical Phibro Animal Health Corp
Publication of EP3454893A1 publication Critical patent/EP3454893A1/en
Publication of EP3454893A4 publication Critical patent/EP3454893A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP16901833.0A 2016-05-11 2016-05-11 A composition comprising antigens and a mucosal adjuvant and a method for using Withdrawn EP3454893A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2016/031902 WO2017196318A1 (en) 2016-05-11 2016-05-11 A composition comprising antigens and a mucosal adjuvant and a method for using

Publications (2)

Publication Number Publication Date
EP3454893A1 EP3454893A1 (en) 2019-03-20
EP3454893A4 true EP3454893A4 (en) 2020-01-01

Family

ID=60267492

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16901833.0A Withdrawn EP3454893A4 (en) 2016-05-11 2016-05-11 A composition comprising antigens and a mucosal adjuvant and a method for using

Country Status (3)

Country Link
EP (1) EP3454893A4 (en)
CA (1) CA3022006A1 (en)
WO (1) WO2017196318A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112457397A (en) * 2020-11-26 2021-03-09 西北农林科技大学 Nano antibody of PRRSV N protein and preparation method and application thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4944942A (en) * 1987-08-27 1990-07-31 Mobay Corporation Intranasal vaccination of horses with inactivated microorganisms or antigenic material
EP1001025A2 (en) * 1998-10-22 2000-05-17 Pfizer Products Inc. Outer membrane proteins from actinobacillus pleuropneumoniae
WO2002049666A2 (en) * 2000-12-19 2002-06-27 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
US20110123570A1 (en) * 2009-11-10 2011-05-26 Boehringer Ingelheim Vetmedica, Inc. Actinobacillus suis antigens
WO2014004361A1 (en) * 2012-06-27 2014-01-03 Merial Limited Attenuated streptococcus suis vaccines and methods of making and use thereof
CN104511015A (en) * 2013-09-30 2015-04-15 普莱柯生物工程股份有限公司 Vaccine composition, preparation method and application thereof
CN110075289A (en) * 2019-04-19 2019-08-02 河南省农业科学院畜牧兽医研究所 A kind of haemophilus parasuis, Streptococcus suis and Actinobacillus pleuropneumoniae triple inactivated vaccine and its application

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2409782T3 (en) * 2004-04-05 2013-06-27 Zoetis P Llc Microfluidified oil-in-water emulsions and vaccine compositions
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
US9393295B2 (en) * 2008-04-28 2016-07-19 Novartis Ag Nanoparticles for use in pharmaceutical compositions
MY186535A (en) * 2011-02-17 2021-07-26 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
WO2012145573A2 (en) * 2011-04-21 2012-10-26 Universiteit Utrecht Holding Bv Streptococcus bacteriophage lysins for treatment of gram positive bacteria in companion animals and livestock

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4944942A (en) * 1987-08-27 1990-07-31 Mobay Corporation Intranasal vaccination of horses with inactivated microorganisms or antigenic material
EP1001025A2 (en) * 1998-10-22 2000-05-17 Pfizer Products Inc. Outer membrane proteins from actinobacillus pleuropneumoniae
WO2002049666A2 (en) * 2000-12-19 2002-06-27 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
US20110123570A1 (en) * 2009-11-10 2011-05-26 Boehringer Ingelheim Vetmedica, Inc. Actinobacillus suis antigens
WO2014004361A1 (en) * 2012-06-27 2014-01-03 Merial Limited Attenuated streptococcus suis vaccines and methods of making and use thereof
CN104511015A (en) * 2013-09-30 2015-04-15 普莱柯生物工程股份有限公司 Vaccine composition, preparation method and application thereof
CN110075289A (en) * 2019-04-19 2019-08-02 河南省农业科学院畜牧兽医研究所 A kind of haemophilus parasuis, Streptococcus suis and Actinobacillus pleuropneumoniae triple inactivated vaccine and its application

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
MAYANK CHATURVEDI ET AL: "A review on mucoadhesive polymer used in nasal drug delivery system", JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH, vol. 2, no. 4, 1 October 2011 (2011-10-01), pages 215 - 222, XP055232682, DOI: 10.4103/2231-4040.90876 *
See also references of WO2017196318A1 *
SHARAD MANGAL ET AL: "Evaluation of mucoadhesive carrier adjuvant: Toward an oral anthrax vaccine", ARTIFICIAL CELLS, NANOMEDICINE AND BIOTECHNOLOGY, vol. 42, no. 1, 1 February 2014 (2014-02-01), US, pages 47 - 57, XP055645252, ISSN: 2169-1401, DOI: 10.3109/21691401.2013.769447 *
WANG SHUJING ET AL: "Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies", PROTEIN & CELL, SPRINGER ASIA, BEIJING, CN, vol. 6, no. 7, 6 May 2015 (2015-05-06), pages 480 - 503, XP035507308, ISSN: 1674-800X, [retrieved on 20150506], DOI: 10.1007/S13238-015-0164-2 *

Also Published As

Publication number Publication date
EP3454893A1 (en) 2019-03-20
CA3022006A1 (en) 2017-11-16
WO2017196318A1 (en) 2017-11-16

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