BR112014032276A2 - construtos de vista-ig e o uso de vista-ig para o tratamento de distúrbios autoimunes, alérgicos e inflamatórios - Google Patents
construtos de vista-ig e o uso de vista-ig para o tratamento de distúrbios autoimunes, alérgicos e inflamatóriosInfo
- Publication number
- BR112014032276A2 BR112014032276A2 BR112014032276A BR112014032276A BR112014032276A2 BR 112014032276 A2 BR112014032276 A2 BR 112014032276A2 BR 112014032276 A BR112014032276 A BR 112014032276A BR 112014032276 A BR112014032276 A BR 112014032276A BR 112014032276 A2 BR112014032276 A2 BR 112014032276A2
- Authority
- BR
- Brazil
- Prior art keywords
- vista
- autoimmune
- allergic
- constructs
- treatment
- Prior art date
Links
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 230000001363 autoimmune Effects 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 238000009877 rendering Methods 0.000 abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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Abstract
resumo patente de invenção: "sistema de comunicação" um terminal de usuário tem uma entrada para receber um sinal de vídeo, e um visor para exibir a um usuário uma imagem de vídeo derivada do sinal de vídeo. uma entrada de seleção é fornecida para receber do usuário pelo menos um efeito para aprimorar a imagem de vídeo derivada do sinal de vídeo. o terminal de usuário tem um dispositivo de renderização para renderizar no visor a imagem de vídeo derivada do sinal de vídeo aprimorada pelo efeito selecionado.
Applications Claiming Priority (6)
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US201261663431P | 2012-06-22 | 2012-06-22 | |
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US201361776234P | 2013-03-11 | 2013-03-11 | |
US201361807135P | 2013-04-01 | 2013-04-01 | |
PCT/US2013/047009 WO2013192504A1 (en) | 2012-06-22 | 2013-06-21 | Novel vista-ig constructs and the use of vista-ig for treatment of autoimmune, allergic and inflammatory disorders |
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BR112014032276A2 true BR112014032276A2 (pt) | 2017-11-28 |
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BR112014032276A BR112014032276A2 (pt) | 2012-06-22 | 2013-06-21 | construtos de vista-ig e o uso de vista-ig para o tratamento de distúrbios autoimunes, alérgicos e inflamatórios |
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US10745467B2 (en) | 2010-03-26 | 2020-08-18 | The Trustees Of Dartmouth College | VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders |
MX342017B (es) * | 2010-03-26 | 2016-09-09 | Dartmouth College | Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos. |
WO2012054509A2 (en) | 2010-10-22 | 2012-04-26 | Dana-Farber Cancer Institute, Inc. | Discovery of regulatory t cells programmed to suppress an immune response |
FI3421486T3 (fi) * | 2012-06-22 | 2023-12-15 | Dartmouth College | Uusia vista-ig-rakenteita ja vista-ig:n käyttö autoimmuuni-, allergia- ja tulehdushäiriöiden hoitamiseksi |
US9890215B2 (en) | 2012-06-22 | 2018-02-13 | King's College London | Vista modulators for diagnosis and treatment of cancer |
JP6368308B2 (ja) | 2012-09-07 | 2018-08-01 | トラスティーズ・オブ・ダートマス・カレッジ | 癌の診断および治療のためのvista調節剤 |
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DK3712174T3 (da) | 2013-12-24 | 2022-04-25 | Janssen Pharmaceutica Nv | Anti-vista antibodies and fragments |
US11014987B2 (en) | 2013-12-24 | 2021-05-25 | Janssen Pharmaceutics Nv | Anti-vista antibodies and fragments, uses thereof, and methods of identifying same |
JP6903432B2 (ja) | 2014-03-12 | 2021-07-14 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | Cnsの疾患および傷害を処置するために全身性調節性t細胞のレベルまたは活性を低下させること |
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CN108025068A (zh) * | 2014-03-12 | 2018-05-11 | 耶达研究与开发有限公司 | 降低系统性调节性t细胞水平或活性来治疗cns的疾病和损伤 |
CN103923934B (zh) * | 2014-03-22 | 2016-11-02 | 复旦大学 | 一种具有免疫负调控作用的基因工程蛋白及其制备方法与应用 |
EP3154585B1 (en) * | 2014-06-11 | 2022-02-23 | Kathy A. Green | Use of vista agonists and antagonists to suppress or enhance humoral immunity |
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CN104257746A (zh) * | 2014-08-29 | 2015-01-07 | 山东科尔生物医药科技开发有限公司 | 一种含有壳寡糖的药物组合物及其制备方法和应用 |
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JOP20150008B1 (ar) * | 2014-11-26 | 2021-08-17 | Janssen Pharmaceutica Nv | أجسام مضادة ل vista وأجزاء منها |
MX2017007136A (es) * | 2014-12-05 | 2017-12-04 | Immunext Inc | Identificacion de vsig8 como el receptor vista putativo y su uso para producir moduladores vista/vsig8. |
EP3270943A4 (en) * | 2015-03-16 | 2018-10-17 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Isolated peptides derived from the b7 ligand dimer interface and uses thereof |
EP3302548A4 (en) * | 2015-06-03 | 2019-01-02 | Dana Farber Cancer Institute, Inc. | Methods to induce conversion of regulatory t cells into effector t cells for cancer immunotherapy |
CA2990360C (en) | 2015-06-24 | 2024-02-13 | Janssen Pharmaceutica Nv | Anti-vista antibodies and fragments |
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2013
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JP2020096628A (ja) | 2020-06-25 |
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CA2877533A1 (en) | 2013-12-27 |
WO2013192504A1 (en) | 2013-12-27 |
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AU2013277051A1 (en) | 2015-02-12 |
TWI677507B (zh) | 2019-11-21 |
CN104619722A (zh) | 2015-05-13 |
EP3421486A1 (en) | 2019-01-02 |
AU2013277051B2 (en) | 2018-06-07 |
TW201936643A (zh) | 2019-09-16 |
DK3421486T3 (da) | 2023-12-04 |
TW201412775A (zh) | 2014-04-01 |
US20180051070A1 (en) | 2018-02-22 |
CN104619722B (zh) | 2022-10-04 |
EP2864352A1 (en) | 2015-04-29 |
HK1214272A1 (zh) | 2016-07-22 |
US20140220012A1 (en) | 2014-08-07 |
JP2018021049A (ja) | 2018-02-08 |
JP2015526064A (ja) | 2015-09-10 |
JP6285923B2 (ja) | 2018-02-28 |
TWI705073B (zh) | 2020-09-21 |
EP2864352B1 (en) | 2018-08-08 |
FI3421486T3 (fi) | 2023-12-15 |
CA2877533C (en) | 2022-08-16 |
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