BR112014031526A2 - promotores para expressar um gene em uma célula - Google Patents

promotores para expressar um gene em uma célula

Info

Publication number
BR112014031526A2
BR112014031526A2 BR112014031526A BR112014031526A BR112014031526A2 BR 112014031526 A2 BR112014031526 A2 BR 112014031526A2 BR 112014031526 A BR112014031526 A BR 112014031526A BR 112014031526 A BR112014031526 A BR 112014031526A BR 112014031526 A2 BR112014031526 A2 BR 112014031526A2
Authority
BR
Brazil
Prior art keywords
promoters
gene
cell
relates
present
Prior art date
Application number
BR112014031526A
Other languages
English (en)
Portuguese (pt)
Inventor
Pieter Los Alrik
Vonk Brenda
Jan Pel Herman
Antonius Damveld Robbertus
Herman Marie Heijne Wilbert
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BR112014031526A2 publication Critical patent/BR112014031526A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2428Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112014031526A 2012-06-19 2013-06-17 promotores para expressar um gene em uma célula BR112014031526A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12172605 2012-06-19
PCT/EP2013/062490 WO2013189878A1 (en) 2012-06-19 2013-06-17 Promoters for expressing a gene in a cell

Publications (1)

Publication Number Publication Date
BR112014031526A2 true BR112014031526A2 (pt) 2017-08-01

Family

ID=48703430

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014031526A BR112014031526A2 (pt) 2012-06-19 2013-06-17 promotores para expressar um gene em uma célula

Country Status (6)

Country Link
US (1) US20150197760A1 (https=)
EP (1) EP2861714A1 (https=)
CN (1) CN104508114A (https=)
BR (1) BR112014031526A2 (https=)
IN (1) IN2014DN10111A (https=)
WO (1) WO2013189878A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013191651A1 (en) * 2012-06-19 2013-12-27 Nanyang Technological University An expression construct for sensing cell density and substrate availability and its use in conversion of hydroxycinnamic acids
BR112018077458A2 (pt) 2016-06-30 2019-04-02 Danisco Us Inc. proteases aspárticas
US10035997B2 (en) * 2016-07-21 2018-07-31 Fornia Biosolutions, Inc. G24 glucoamylase compositions and methods
US11634673B2 (en) * 2017-09-29 2023-04-25 Dupont Nutrition Biosciences Aps Production of brewer's wort having increase fermentable sugars for fermentation
BR112020018294A2 (pt) 2018-03-09 2020-12-29 Danisco Us Inc. Glucoamilases e métodos de uso dos mesmos
CN110331144B (zh) * 2019-08-01 2023-01-20 天津科技大学 一种真菌启动子及其应用
CN112795567B (zh) * 2020-12-24 2022-04-15 广东省微生物研究所(广东省微生物分析检测中心) 一种深海真菌FS140 O-甲基转移酶基因GliM启动子及其应用
CN113061538A (zh) * 2021-03-23 2021-07-02 江南大学 一种构巢曲霉自诱导型表达系统及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198345A (en) 1985-04-15 1993-03-30 Gist-Brocades N.V. Vectors in use in filamentous fungi
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
CA1341226C (en) 1988-08-16 2001-05-01 Wim Van Hartingsveldt Gene replacement as a tool for the construction of aspergillus strains
AU4712193A (en) 1992-08-19 1994-03-15 Alko Group Limited Fungal promoters active in the presence of glucose
DE69332030T2 (de) 1992-12-10 2002-10-02 Dsm N.V., Heerlen Herstellung von heterologen proteinen in filamentösen fungi
DE69432543T2 (de) 1993-07-23 2003-12-24 Dsm N.V., Te Heerlen Selektionmarker-genfreie rekombinante Stämme: Verfahren zur ihrer Herstellung und die Verwendung dieser Stämme
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
US5795737A (en) 1994-09-19 1998-08-18 The General Hospital Corporation High level expression of proteins
PL335227A1 (en) 1997-02-20 2000-04-10 Dsm Nv Industrial-scale production of valuable compounds by fermentation in a chemically defined medium
PL336345A1 (en) 1997-04-11 2000-06-19 Dsm Nv Genic conversion as a tool for constructing recombined filiform fungi
WO1999032617A2 (en) 1997-12-22 1999-07-01 Dsm N.V. Expression cloning in filamentous fungi
AU7288100A (en) 1999-09-17 2001-04-24 Dsm N.V. Regulation of secondary metabolite production
US9243043B2 (en) 2004-04-02 2016-01-26 Dsm Ip Assets B.V. Filamentous fungal mutants with improved homologous recombination efficiency
JP4783359B2 (ja) 2004-04-16 2011-09-28 ディーエスエム アイピー アセッツ ビー.ブイ. 真菌細胞において遺伝子を発現させるための真菌プロモーター
EP1856263A1 (en) 2005-03-01 2007-11-21 DSMIP Assets B.V. Aspergillus promotors for expressing a gene in a fungal cell
AU2008214663B2 (en) 2007-02-15 2013-10-03 Dsm Ip Assets B.V. A recombinant host cell for the production of a compound of interest
US20100120154A1 (en) 2007-03-21 2010-05-13 Dsm Ip Assets B.V. Method for homologous recombination
CA2724076C (en) * 2008-05-11 2018-11-27 Universiteit Stellenbosch Heterologous expression of fungal cellobiohydrolases in yeast
MX2012005271A (es) 2009-11-04 2012-06-28 Dsm Ip Assets Bv Transformantes de talaromyces.

Also Published As

Publication number Publication date
EP2861714A1 (en) 2015-04-22
WO2013189878A1 (en) 2013-12-27
US20150197760A1 (en) 2015-07-16
CN104508114A (zh) 2015-04-08
IN2014DN10111A (https=) 2015-08-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]