BR112014029834A2 - polipeptídeo ou um sal, formulação farmacêutica, polipeptídeo ou sal, métodos de determinação se as células t reconhecem um polipeptídeo ou sal, de tratamento de um indivíduo ou de prevenção de uma alergia em um indivíduo a cladosporium e/ou alternaria, e para preparar uma formulação farmacêutica, e, uso de um polipeptídeo ou sal - Google Patents
polipeptídeo ou um sal, formulação farmacêutica, polipeptídeo ou sal, métodos de determinação se as células t reconhecem um polipeptídeo ou sal, de tratamento de um indivíduo ou de prevenção de uma alergia em um indivíduo a cladosporium e/ou alternaria, e para preparar uma formulação farmacêutica, e, uso de um polipeptídeo ou salInfo
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- BR112014029834A2 BR112014029834A2 BR112014029834A BR112014029834A BR112014029834A2 BR 112014029834 A2 BR112014029834 A2 BR 112014029834A2 BR 112014029834 A BR112014029834 A BR 112014029834A BR 112014029834 A BR112014029834 A BR 112014029834A BR 112014029834 A2 BR112014029834 A2 BR 112014029834A2
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- polypeptide
- salt
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0002—Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01138—Mannitol 2-dehydrogenase (NADP+) (1.1.1.138)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
Abstract
1 / 1 resumo âpolipeptãdeo ou um sal, formulaãão farmacãutica, polipeptãdeo ou sal, mãtodos de determinaãão se as cãlulas t reconhecem um polipeptãdeo ou sal, de tratamento de um indivãduo ou de prevenãão de uma alergia em um indivãduo a cladosporium e/ou alternaria, e para preparar uma formulaãão farmacãutica, e, uso de um polipeptãdeo ou salâ polipeptãdeos que podem ser usados para a prevenã§ã£o ou tratamento de alergia aos mofos dos gãªneros cladosporium e/ou alternaria, tãªm atã© 30 aminoã¡cidos de comprimento e compreendem: (i) a sequãªncia de aminoã¡cidos: (a) ggykaavrptmle (seq id no: 35; cla35), (b) aevyqklksltkk (seq id no: 31; cla16), (c) vaityasraqgae (seq id no: 32; cla25), (d) ghhfkergtgslvit (seq id no: 33; cla26), ou (e) anytqtktvsirl (seq id no: 34; cla29); ou (ii) uma sequãªncia variante contendo epãtopo de cã©lulas t que ã© uma referida sequãªncia de aminoã¡cidos (i) tendo atã© seis modificaã§ãµes de aminoã¡cido, cada sendo independentemente uma deleã§ã£o, substituiã§ã£o ou inserã§ã£o.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1209862.0A GB201209862D0 (en) | 2012-06-01 | 2012-06-01 | Cladosporium peptides |
PCT/GB2013/051440 WO2013179044A2 (en) | 2012-06-01 | 2013-05-30 | Cladosporium peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014029834A2 true BR112014029834A2 (pt) | 2017-07-25 |
Family
ID=46582262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014029834A BR112014029834A2 (pt) | 2012-06-01 | 2013-05-30 | polipeptídeo ou um sal, formulação farmacêutica, polipeptídeo ou sal, métodos de determinação se as células t reconhecem um polipeptídeo ou sal, de tratamento de um indivíduo ou de prevenção de uma alergia em um indivíduo a cladosporium e/ou alternaria, e para preparar uma formulação farmacêutica, e, uso de um polipeptídeo ou sal |
Country Status (16)
Country | Link |
---|---|
US (1) | US9850281B2 (pt) |
EP (1) | EP2855514A2 (pt) |
JP (1) | JP2015520171A (pt) |
KR (1) | KR20150016622A (pt) |
CN (1) | CN104507960A (pt) |
AU (1) | AU2013269327A1 (pt) |
BR (1) | BR112014029834A2 (pt) |
CA (1) | CA2875131A1 (pt) |
CL (1) | CL2014003289A1 (pt) |
EA (1) | EA201492270A1 (pt) |
GB (2) | GB201209862D0 (pt) |
HK (1) | HK1202554A1 (pt) |
IL (1) | IL235842A0 (pt) |
MX (1) | MX2014014460A (pt) |
SG (1) | SG11201407945SA (pt) |
WO (1) | WO2013179044A2 (pt) |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT400722B (de) * | 1993-08-27 | 1996-03-25 | Biomay Prod & Handel | Rekombinante cladosporium herbarum allergene |
AT401181B (de) | 1994-11-02 | 1996-07-25 | Biomay Prod & Handel | Rekombinante dna moleküle |
AT403166B (de) * | 1995-03-02 | 1997-11-25 | Biomay Prod & Handel | Rekombinante dna moleküle, die für polypeptide kodieren, die die antigenität der allergene clah8 und clah12 besitzen |
CA2217173C (en) | 1997-11-25 | 2008-04-01 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Health | Isolation of a cdna clone encoding a subunit of the alternaria alternata major allergen alt a 1, and production of recombinant protein thereof |
US7247441B2 (en) | 2002-03-28 | 2007-07-24 | Biomay Produktions- Und Handels-Aktienge Sellschaft | Nucleic acid sequence and protein in addition to polypeptides coding for mannitol dehydrogenases or parts thereof and the production and use thereof in diagnosis and therapy |
PL2083856T3 (pl) | 2007-08-15 | 2011-04-29 | Circassia Ltd | Peptydy do odczulania na alergeny |
CN101178406A (zh) | 2007-12-05 | 2008-05-14 | 杭州浙大生物基因工程有限公司 | 过敏原特异性抗体IgE ELISA检测试剂盒及其制备方法 |
JP5705113B2 (ja) * | 2008-08-15 | 2015-04-22 | サーカッシア リミテッド | Il−10産生の刺激のためのアレルゲン由来のt細胞抗原 |
CN101387643A (zh) | 2008-10-20 | 2009-03-18 | 杭州浙大生物基因工程有限公司 | 多通道过敏原快速检测试剂盒及其制备方法 |
CN101393215A (zh) | 2008-11-17 | 2009-03-25 | 杭州浙大生物基因工程有限公司 | 多通道吸入型过敏原快速检测试剂盒及其制备方法 |
GB0821806D0 (en) | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
GB201002559D0 (en) | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
CN102212531A (zh) | 2010-04-02 | 2011-10-12 | 复旦大学 | 一种重组多主枝孢霉变应原Cla h8蛋白的制备方法及其用途 |
KR20130118884A (ko) | 2010-10-15 | 2013-10-30 | 알크-아벨로 에이/에스 | 알레르겐 소스 물질로부터 유도된 무관련 알레르겐을 이용한 과민성 면역반응의 억제 |
WO2013119853A1 (en) * | 2012-02-07 | 2013-08-15 | La Jolla Institute For Allergy And Immunology | Epitopes from allergen proteins and methods and uses for immune response modulation |
-
2012
- 2012-06-01 GB GBGB1209862.0A patent/GB201209862D0/en not_active Ceased
-
2013
- 2013-05-30 JP JP2015514590A patent/JP2015520171A/ja active Pending
- 2013-05-30 GB GB1422973.6A patent/GB2518092A/en not_active Withdrawn
- 2013-05-30 WO PCT/GB2013/051440 patent/WO2013179044A2/en active Application Filing
- 2013-05-30 SG SG11201407945SA patent/SG11201407945SA/en unknown
- 2013-05-30 MX MX2014014460A patent/MX2014014460A/es unknown
- 2013-05-30 KR KR1020147037164A patent/KR20150016622A/ko not_active Application Discontinuation
- 2013-05-30 BR BR112014029834A patent/BR112014029834A2/pt not_active IP Right Cessation
- 2013-05-30 EP EP13726838.9A patent/EP2855514A2/en not_active Withdrawn
- 2013-05-30 EA EA201492270A patent/EA201492270A1/ru unknown
- 2013-05-30 AU AU2013269327A patent/AU2013269327A1/en not_active Abandoned
- 2013-05-30 US US14/403,462 patent/US9850281B2/en not_active Expired - Fee Related
- 2013-05-30 CN CN201380040588.7A patent/CN104507960A/zh active Pending
- 2013-05-30 CA CA2875131A patent/CA2875131A1/en not_active Abandoned
-
2014
- 2014-11-23 IL IL235842A patent/IL235842A0/en unknown
- 2014-12-01 CL CL2014003289A patent/CL2014003289A1/es unknown
-
2015
- 2015-03-19 HK HK15102838.5A patent/HK1202554A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013179044A3 (en) | 2014-03-06 |
US9850281B2 (en) | 2017-12-26 |
WO2013179044A2 (en) | 2013-12-05 |
EP2855514A2 (en) | 2015-04-08 |
US20150218215A1 (en) | 2015-08-06 |
JP2015520171A (ja) | 2015-07-16 |
IL235842A0 (en) | 2015-01-29 |
MX2014014460A (es) | 2015-02-12 |
KR20150016622A (ko) | 2015-02-12 |
AU2013269327A1 (en) | 2014-12-18 |
HK1202554A1 (en) | 2015-10-02 |
CN104507960A (zh) | 2015-04-08 |
CL2014003289A1 (es) | 2015-05-22 |
GB201209862D0 (en) | 2012-07-18 |
CA2875131A1 (en) | 2013-12-05 |
EA201492270A1 (ru) | 2015-09-30 |
GB2518092A (en) | 2015-03-11 |
SG11201407945SA (en) | 2014-12-30 |
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