BR112014026399A2 - composto da fórmula (i) e da fórmula (ii), composição farmacêutica, método para o tratamento de uma condição ou distúrbio no qual bloqueadores de canal ttx-s estão envolvidos em um animal, incluindo humano, uso e processo para preparar uma composição farmacêutica - Google Patents

composto da fórmula (i) e da fórmula (ii), composição farmacêutica, método para o tratamento de uma condição ou distúrbio no qual bloqueadores de canal ttx-s estão envolvidos em um animal, incluindo humano, uso e processo para preparar uma composição farmacêutica

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Publication number
BR112014026399A2
BR112014026399A2 BR112014026399A BR112014026399A BR112014026399A2 BR 112014026399 A2 BR112014026399 A2 BR 112014026399A2 BR 112014026399 A BR112014026399 A BR 112014026399A BR 112014026399 A BR112014026399 A BR 112014026399A BR 112014026399 A2 BR112014026399 A2 BR 112014026399A2
Authority
BR
Brazil
Prior art keywords
formula
pharmaceutical composition
ttx
disorder
animal
Prior art date
Application number
BR112014026399A
Other languages
English (en)
Other versions
BR112014026399A8 (pt
BR112014026399B1 (pt
Inventor
Kawamura Kiyoshi
Morita Mikio
Yamagishi Tatsuya
Original Assignee
Raqualia Pharma Inc
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Publication date
Application filed by Raqualia Pharma Inc filed Critical Raqualia Pharma Inc
Publication of BR112014026399A2 publication Critical patent/BR112014026399A2/pt
Publication of BR112014026399A8 publication Critical patent/BR112014026399A8/pt
Publication of BR112014026399B1 publication Critical patent/BR112014026399B1/pt

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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EA034891B1 (ru) * 2015-03-06 2020-04-02 Фармакеа, Инк. Фторированные ингибиторы лизилоксидазоподобного фермента-2 и их применение
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JP7097874B2 (ja) 2016-09-07 2022-07-08 ファーマケア，インク． リシルオキシダーゼ様２阻害剤の使用
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RU2768149C2 (ru) * 2017-06-20 2022-03-23 Раквалиа Фарма Инк. ПРОИЗВОДНЫЕ АМИДА В КАЧЕСТВЕ БЛОКАТОРОВ Nav1.7 И Nav1.8
CN111132961A (zh) * 2017-08-31 2020-05-08 拉夸里亚创药株式会社 作为ttx-s阻断剂的双芳氧基衍生物
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