BR112014025702A2 - compostos de tiofeno fotodinâmicos a base de metal e seus usos - Google Patents
compostos de tiofeno fotodinâmicos a base de metal e seus usosInfo
- Publication number
- BR112014025702A2 BR112014025702A2 BR112014025702-7A BR112014025702A BR112014025702A2 BR 112014025702 A2 BR112014025702 A2 BR 112014025702A2 BR 112014025702 A BR112014025702 A BR 112014025702A BR 112014025702 A2 BR112014025702 A2 BR 112014025702A2
- Authority
- BR
- Brazil
- Prior art keywords
- metal based
- thiophene compounds
- based photodynamic
- compositions
- photodynamic
- Prior art date
Links
- 239000002184 metal Substances 0.000 title abstract 3
- 150000003577 thiophenes Chemical class 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000003463 hyperproliferative effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000004659 sterilization and disinfection Methods 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0046—Ruthenium compounds
- C07F15/0053—Ruthenium compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/002—Osmium compounds
- C07F15/0026—Osmium compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
compostos de tiofeno fotodinâmicos a base de metal e seus usos a presente invenção se refere à composições que incluem compostos de tiofeno fotodinâmicos baseados em metal sintonizáveis úteis como agentes terapêuticos e como agentes de diagnóstico in vivo para tratar ou prevenir doenças que envolvem etiologia celular indesejada e/ou hiperproliferativa incluindo câncer e doenças associadas a células indesejadas e/ou hiperproliferativas. as composições também são úteis para tratar doenças infecciosas e para desinfecção patogênica e/ou esterilização.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261624391P | 2012-04-15 | 2012-04-15 | |
| US61/624.391 | 2012-04-15 | ||
| PCT/US2013/036595 WO2013158550A1 (en) | 2012-04-15 | 2013-04-15 | Metal-based thiophene photodynamic compounds and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014025702A2 true BR112014025702A2 (pt) | 2018-12-18 |
| BR112014025702B1 BR112014025702B1 (pt) | 2022-10-11 |
Family
ID=48576499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014025702-7A BR112014025702B1 (pt) | 2012-04-15 | 2013-04-15 | Compostos de tiofeno fotodinâmicos a base de metal e seus usos |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9345769B2 (pt) |
| EP (1) | EP2854948B1 (pt) |
| CN (1) | CN105120957B (pt) |
| BR (1) | BR112014025702B1 (pt) |
| CA (1) | CA2883068C (pt) |
| ES (1) | ES2764421T3 (pt) |
| RU (1) | RU2677855C2 (pt) |
| WO (1) | WO2013158550A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2682674C2 (ru) | 2013-03-15 | 2019-03-20 | Шерри Энн МАКФАРЛЭНД | Координационные комплексы на основе металлов в качестве фотодинамических соединений и их применение |
| WO2015166333A1 (en) * | 2014-04-29 | 2015-11-05 | Theralase Technologies, Inc. | Apparatus and method for multiwavelength photodynamic therapy |
| US9969759B2 (en) | 2014-05-22 | 2018-05-15 | Northwestern University | Duplex-selective organometallic DNA intercalators |
| US10111936B2 (en) | 2015-01-19 | 2018-10-30 | Theralase Technologies, Inc. | Metal-glycoprotein complexes and photodynamic therapy of immune privileged sites with same |
| BR112017015499A2 (pt) * | 2015-01-19 | 2018-01-30 | Theralase Tech Inc | ?composição, e, métodos para tratar uma condição associada com células hiperprolifereantes, e para destruir uma célula microbiana? |
| WO2017058085A1 (en) * | 2015-10-01 | 2017-04-06 | Richter Life Science Development Ab | Detection of microbial peptides |
| US10335608B2 (en) | 2016-04-20 | 2019-07-02 | Theralase Technologies, Inc. | Photodynamic compounds and methods for activating them using ionizing radiation and/or other electromagnetic radiation for therapy and/or diagnostics |
| CA3062883C (en) * | 2017-05-11 | 2024-04-02 | Theralase Biotech, Inc. | Vaccine containing cancer cells inactivated by photodynamic treatment with metal-based coordination complexes, and immunotherapy method using same |
| EP3697397A4 (en) * | 2017-10-19 | 2021-06-16 | Texas State University | PHOTO-ACTIVATED PROPHARMACON AGAINST CANCER |
| CA3038108A1 (en) | 2018-03-26 | 2019-09-26 | Theralase Technologies, Inc. | Method for treating conditions associated with hyperproliferating cells comprising combined administration of a cannabinoid receptor agonist and radiation therapy |
| CN110396092B (zh) * | 2019-07-09 | 2020-06-30 | 北京师范大学 | 含噻吩基钌配合物作为高效单线态氧产生光敏剂 |
| CN110872330B (zh) * | 2019-11-19 | 2021-09-21 | 华南理工大学 | 一种联吡啶钌邻菲罗啉苯并咪唑配合物及其制备方法和用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2449316A1 (en) * | 2001-06-06 | 2002-12-12 | Brookhaven Science Associates | Novel metalloporphyrins and their uses as radiosensitizers for radiation therapy |
| PL197232B1 (pl) * | 2004-06-03 | 2008-03-31 | Univ Wroclawski | Nowe kompleksy kationowe żelaza(II) i kobaltu(II) z 2,2'-bipirydyną, z 2,2'-bichinoliną i 1,10-fenantroliną oraz ich pochodnymi, sposób wytwarzania tych kompleksów i zastosowanie |
-
2013
- 2013-04-15 ES ES13726902T patent/ES2764421T3/es active Active
- 2013-04-15 US US13/863,089 patent/US9345769B2/en active Active
- 2013-04-15 CA CA2883068A patent/CA2883068C/en active Active
- 2013-04-15 BR BR112014025702-7A patent/BR112014025702B1/pt active IP Right Grant
- 2013-04-15 EP EP13726902.3A patent/EP2854948B1/en active Active
- 2013-04-15 WO PCT/US2013/036595 patent/WO2013158550A1/en active Search and Examination
- 2013-04-15 CN CN201380030975.2A patent/CN105120957B/zh active Active
- 2013-04-15 RU RU2014145281A patent/RU2677855C2/ru active
-
2016
- 2016-04-15 US US15/130,893 patent/US9676806B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105120957A (zh) | 2015-12-02 |
| RU2677855C2 (ru) | 2019-01-22 |
| US9345769B2 (en) | 2016-05-24 |
| BR112014025702B1 (pt) | 2022-10-11 |
| US20160229878A1 (en) | 2016-08-11 |
| CA2883068A1 (en) | 2013-10-24 |
| US9676806B2 (en) | 2017-06-13 |
| WO2013158550A1 (en) | 2013-10-24 |
| CA2883068C (en) | 2021-04-20 |
| EP2854948B1 (en) | 2019-09-25 |
| EP2854948A1 (en) | 2015-04-08 |
| CN105120957B (zh) | 2019-06-25 |
| RU2014145281A (ru) | 2016-06-10 |
| ES2764421T3 (es) | 2020-06-03 |
| US20130331367A1 (en) | 2013-12-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: SHERRI ANN MCFARLAND (CA) |
|
| B25G | Requested change of headquarter approved |
Owner name: SHERRI ANN MCFARLAND (US) |
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| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.21 NA RPI NO 2628 DE 18/05/2021 POR TER SIDO INDEVIDA. |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B09X | Republication of the decision to grant [chapter 9.1.3 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/04/2013, OBSERVADAS AS CONDICOES LEGAIS |