BR112014016427A8 - processo para a preparação de derivados de 2-fenil-[1,2,4]triazolo[1,5-a]piridina - Google Patents
processo para a preparação de derivados de 2-fenil-[1,2,4]triazolo[1,5-a]piridinaInfo
- Publication number
- BR112014016427A8 BR112014016427A8 BR112014016427A BR112014016427A BR112014016427A8 BR 112014016427 A8 BR112014016427 A8 BR 112014016427A8 BR 112014016427 A BR112014016427 A BR 112014016427A BR 112014016427 A BR112014016427 A BR 112014016427A BR 112014016427 A8 BR112014016427 A8 BR 112014016427A8
- Authority
- BR
- Brazil
- Prior art keywords
- triazolo
- phenyl
- pyridine derivatives
- preparation
- halogen
- Prior art date
Links
- ZMVHJRCJDDSDSS-UHFFFAOYSA-N 2-phenyl-[1,2,4]triazolo[1,5-a]pyridine Chemical class C1=CC=CC=C1C1=NN2C=CC=CC2=N1 ZMVHJRCJDDSDSS-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical class C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12154786 | 2012-02-09 | ||
| PCT/EP2013/052362 WO2013117610A1 (en) | 2012-02-09 | 2013-02-07 | Process for the preparation of 2-phenyl-[1,2,4]triazolo[1,5-a]pyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014016427A2 BR112014016427A2 (pt) | 2017-06-13 |
| BR112014016427A8 true BR112014016427A8 (pt) | 2017-07-04 |
Family
ID=47664298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014016427A BR112014016427A8 (pt) | 2012-02-09 | 2013-02-07 | processo para a preparação de derivados de 2-fenil-[1,2,4]triazolo[1,5-a]piridina |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9115130B2 (en:Method) |
| EP (1) | EP2812330B1 (en:Method) |
| JP (1) | JP6122034B2 (en:Method) |
| KR (1) | KR20140128998A (en:Method) |
| CN (1) | CN104093718B (en:Method) |
| BR (1) | BR112014016427A8 (en:Method) |
| CA (1) | CA2858778A1 (en:Method) |
| ES (1) | ES2558618T3 (en:Method) |
| MX (1) | MX348447B (en:Method) |
| RU (1) | RU2620379C2 (en:Method) |
| WO (1) | WO2013117610A1 (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016017719A1 (ja) | 2014-07-30 | 2016-02-04 | 持田製薬株式会社 | ピラゾール誘導体の製造方法 |
| WO2016017711A1 (ja) * | 2014-07-30 | 2016-02-04 | 持田製薬株式会社 | ピラゾール誘導体の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4358454A (en) * | 1982-01-08 | 1982-11-09 | Schering Corporation | 1,3,4-Triazolo[1,5-a]pyridines |
| JP4101755B2 (ja) * | 2001-10-08 | 2008-06-18 | エフ．ホフマン−ラ ロシュ アーゲー | ８−アミノ−〔１，２，４〕トリアゾロ〔１，５−ａ〕ピリジン−６−カルボン酸アミド |
| JP2011032225A (ja) * | 2009-08-03 | 2011-02-17 | Gifu Ichi | １，２，４−トリアゾール誘導体の製造方法 |
| US8349824B2 (en) * | 2010-12-07 | 2013-01-08 | Hoffmann-La Roche Inc. | Triazolopyridine compounds |
-
2013
- 2013-02-07 RU RU2014134278A patent/RU2620379C2/ru not_active IP Right Cessation
- 2013-02-07 EP EP13702648.0A patent/EP2812330B1/en not_active Not-in-force
- 2013-02-07 ES ES13702648.0T patent/ES2558618T3/es active Active
- 2013-02-07 KR KR1020147022111A patent/KR20140128998A/ko not_active Ceased
- 2013-02-07 CA CA2858778A patent/CA2858778A1/en not_active Abandoned
- 2013-02-07 WO PCT/EP2013/052362 patent/WO2013117610A1/en active Application Filing
- 2013-02-07 JP JP2014556039A patent/JP6122034B2/ja active Active
- 2013-02-07 BR BR112014016427A patent/BR112014016427A8/pt not_active Application Discontinuation
- 2013-02-07 CN CN201380006265.6A patent/CN104093718B/zh not_active Expired - Fee Related
- 2013-02-07 MX MX2014008814A patent/MX348447B/es active IP Right Grant
-
2014
- 2014-08-08 US US14/455,773 patent/US9115130B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140128998A (ko) | 2014-11-06 |
| WO2013117610A1 (en) | 2013-08-15 |
| JP2015511235A (ja) | 2015-04-16 |
| US20140350259A1 (en) | 2014-11-27 |
| BR112014016427A2 (pt) | 2017-06-13 |
| CA2858778A1 (en) | 2013-08-15 |
| MX348447B (es) | 2017-06-13 |
| HK1197244A1 (zh) | 2015-01-09 |
| CN104093718B (zh) | 2016-05-04 |
| RU2014134278A (ru) | 2016-03-27 |
| CN104093718A (zh) | 2014-10-08 |
| RU2620379C2 (ru) | 2017-05-25 |
| MX2014008814A (es) | 2014-10-24 |
| EP2812330A1 (en) | 2014-12-17 |
| US9115130B2 (en) | 2015-08-25 |
| EP2812330B1 (en) | 2015-12-02 |
| JP6122034B2 (ja) | 2017-04-26 |
| ES2558618T3 (es) | 2016-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014007193A2 (pt) | derivados de pirazoloquinolinona, preparação dos mesmos e uso terapêutico dos mesmos | |
| BR112014031068A2 (pt) | derivados piridinona e piridazinona | |
| BR112014022000A2 (pt) | compostos à base de pirazol[1,5-a]pirimidina, seu uso e composições que os compreende | |
| BR112014003079A2 (pt) | derivado de 1,2,3,4-tetra-hidroquinolina útil para o tratamento de diabetes | |
| BR112013029640A2 (pt) | derivados de piridina e pirazina | |
| BR112015002118A2 (pt) | 4-metil-2,3,5,9,9b-pentaaza-ciclopenta[a]naftalenos | |
| BR112012015916A2 (pt) | derivados de pirazina e seu uso no tratamento de distúrbios neurológicos | |
| BR112015020772A2 (pt) | compostos de pirimidina e piridina e seu uso | |
| BR112014010576B8 (pt) | compostos inibidores de neprilisina (nep), seus usos, processo de preparação dos compostos e composição farmacêutica compreendendo os compostos | |
| BR112015012454A8 (pt) | compostos inibidores de atr quinase, seu uso, composição farmacêutica compreendendo os mesmos, seus intermediários e método de preparação | |
| BR112015028501A2 (pt) | derivados de bipirazol como inibidores de jak | |
| BR112014027236A2 (pt) | pirrolidinas substituídas como um fator inibidor de xia para o tratamento de doenças tromboembolíticas | |
| BR112015003859A2 (pt) | compostos de pirazolopirimidina como inibidores de quinase | |
| EA201490888A1 (ru) | Новые производные пурина и их применение для лечения заболевания | |
| BR112015009395A2 (pt) | processo para preparação de derivados do ácido biliar | |
| CU20110083A7 (es) | Compuestos heteroaromáticos espirocíclicos fusionados para el tratamiento de infecciones bacterianas | |
| BR112015016395A2 (pt) | pirazóis 3-substituídos e uso como inibidores de dlk | |
| BR112014003587A2 (pt) | derivados de 5-flúor-4-imino-3-(substituído)-3,4-di-hidropirimidin-2(1h)ona | |
| EA201200176A1 (ru) | Производные оксазина и их применение для лечения неврологических нарушений | |
| BR112014005226A2 (pt) | derivados de benzonitrila como inibidores de cinase | |
| PH12014500209A1 (en) | Substituted quinolines and their use as medicaments | |
| BR112015005862A2 (pt) | derivados de hidropirrolpirrol para uso como inibidores de ácido graxo sintase | |
| BR112013031405A2 (pt) | piridopirazinas substituídas como novos inibidores de syk | |
| BR112013019354A2 (pt) | derivados de (1,2,4)triazolo[4,3-a]quinoxalina como inibidores de fosfodiesterases | |
| BR112013019160A2 (pt) | novos compostos, composição farmacêutica, uso, processos e métodos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |