BR112014014814A2 - dispositivo médico - Google Patents

dispositivo médico

Info

Publication number
BR112014014814A2
BR112014014814A2 BR112014014814A BR112014014814A BR112014014814A2 BR 112014014814 A2 BR112014014814 A2 BR 112014014814A2 BR 112014014814 A BR112014014814 A BR 112014014814A BR 112014014814 A BR112014014814 A BR 112014014814A BR 112014014814 A2 BR112014014814 A2 BR 112014014814A2
Authority
BR
Brazil
Prior art keywords
drug
medical device
lubricant
lipophilic
weight
Prior art date
Application number
BR112014014814A
Other languages
English (en)
Other versions
BR112014014814A8 (pt
BR112014014814B1 (pt
Inventor
Caroline Berg Madeleine
Speck Thomas
Original Assignee
Innora Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innora Gmbh filed Critical Innora Gmbh
Publication of BR112014014814A2 publication Critical patent/BR112014014814A2/pt
Publication of BR112014014814A8 publication Critical patent/BR112014014814A8/pt
Publication of BR112014014814B1 publication Critical patent/BR112014014814B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/104—Balloon catheters used for angioplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/452—Lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/10—Materials for lubricating medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes

Abstract

resumo dispositivo médico a presente invenção refere-se a um dispositivo médico que carrega pelo menos sobre uma porção de sua superfície pelo menos um fármaco ou preparação de fármaco e pelo menos um lubrificante lipofílico em razão de 0,1- 500% em peso do pelo menos um lubrificante em relação a 100% em peso do fármaco, em que a pelo menos um fármaco é selecionado a partir de paclitaxel, trióxido de arsênico e derivados lipofílicos de corticoides e fármacos limus selecionados e o pelo menos um lubrificante lipofílico é um sal de ácido monocarboxílico c6-c30.
BR112014014814A 2011-12-23 2012-12-14 dispositivo médico BR112014014814B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2011/073946 WO2013091722A1 (en) 2011-12-23 2011-12-23 Drug-coated medical devices
PCT/EP2012/075563 WO2013092416A1 (en) 2011-12-23 2012-12-14 Drug-coated medical devices

Publications (3)

Publication Number Publication Date
BR112014014814A2 true BR112014014814A2 (pt) 2017-06-13
BR112014014814A8 BR112014014814A8 (pt) 2017-06-13
BR112014014814B1 BR112014014814B1 (pt) 2020-04-22

Family

ID=47458936

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014014814A BR112014014814B1 (pt) 2011-12-23 2012-12-14 dispositivo médico

Country Status (12)

Country Link
US (1) US9233191B2 (pt)
EP (1) EP2793967B1 (pt)
JP (1) JP6174038B2 (pt)
KR (1) KR101943143B1 (pt)
CN (1) CN104010671B (pt)
AU (1) AU2012358032B2 (pt)
BR (1) BR112014014814B1 (pt)
CA (1) CA2857410C (pt)
ES (1) ES2550350T3 (pt)
MX (1) MX360002B (pt)
SG (1) SG11201402654TA (pt)
WO (2) WO2013091722A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013110294B4 (de) * 2013-09-18 2016-07-07 Innora Gmbh Limus-Depot-Formulierung auf Ballonkathetern
US9675734B2 (en) 2014-08-29 2017-06-13 Invatec S.P.A. Medical balloon coated with therapeutic agent, carboxylic acid, and salt thereof
CA3000361A1 (en) 2015-10-02 2017-04-06 Ethicon, Inc. Methods and systems for treating medical devices and fluids
JP6726762B2 (ja) * 2016-04-19 2020-07-22 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 滲出バルーン装置
WO2018050916A1 (en) * 2016-09-19 2018-03-22 Biotronik Ag Polymer-free drug eluting vascular stents
CN108211094B (zh) * 2016-12-19 2023-12-05 先健科技(深圳)有限公司 药物涂层球囊
EP3558408B1 (en) * 2016-12-22 2024-04-17 Biotronik AG Intratumoral drug delivery materials and methods for treating breast cancer
CN111944595B (zh) * 2020-08-21 2022-08-09 健尔康医疗科技股份有限公司 一种医用外科器械用润滑剂及其制备和使用方法

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US5674192A (en) 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5199951A (en) 1990-05-17 1993-04-06 Wayne State University Method of drug application in a transporting medium to an arterial wall injured during angioplasty
US5324261A (en) 1991-01-04 1994-06-28 Medtronic, Inc. Drug delivery balloon catheter with line of weakness
US5893840A (en) 1991-01-04 1999-04-13 Medtronic, Inc. Releasable microcapsules on balloon catheters
WO1994023787A1 (en) 1993-04-22 1994-10-27 Rammler David H Sampling balloon catheter
US6159978A (en) 1997-05-28 2000-12-12 Aventis Pharmaceuticals Product, Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
US6306166B1 (en) 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US7445792B2 (en) 2003-03-10 2008-11-04 Abbott Laboratories Medical device having a hydration inhibitor
US6419692B1 (en) 1999-02-03 2002-07-16 Scimed Life Systems, Inc. Surface protection method for stents and balloon catheters for drug delivery
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US8182527B2 (en) * 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
ES2289153T7 (es) 2001-11-08 2009-06-18 Atrium Medical Corporation Dispositivo intraluminal con un revestimiento que contiene un agente terapeutico.
US7008979B2 (en) * 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
US7108684B2 (en) 2003-01-02 2006-09-19 Novoste Corporation Drug delivery balloon catheter
US20040213826A1 (en) * 2003-04-28 2004-10-28 Marx Steven O. Medical devices and methods for inhibiting proliferation of smooth muscle cells
WO2005027994A2 (en) 2003-09-15 2005-03-31 Atrium Medical Corporation Application of a therapeutic substance to a tissue location using a porous medical device
NZ574597A (en) 2006-07-03 2011-11-25 Hemoteq Ag Stent coated with a biodegradable polymer and rapamycin
EP1913962A1 (en) * 2006-10-22 2008-04-23 Ophir Perelson Expandable medical device for the treatment and prevention of cardiovascular diseases
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NZ588816A (en) * 2007-01-21 2011-11-25 Hemoteq Ag Medical device for the treatment of stenoses of corporal lumina and for the prevention of impending restenoses
DE102007036685A1 (de) 2007-08-03 2009-02-05 Innora Gmbh Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung
AU2007361589B9 (en) 2007-11-21 2014-05-08 Invatec S.P.A. Balloon for the treatment of stenosis and method for manufacturing the balloon
CA2719222C (en) 2008-03-28 2018-07-24 Surmodics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
US8092822B2 (en) * 2008-09-29 2012-01-10 Abbott Cardiovascular Systems Inc. Coatings including dexamethasone derivatives and analogs and olimus drugs
BRPI0919794A2 (pt) * 2008-10-03 2015-12-15 Elixir Medical Corp dispositivo para uso intracorpóreo, e, composto
EP2381963A4 (en) 2009-01-21 2014-07-02 Meril Life Sciences Private Ltd MEDICAL DEVICE WITH FORMULATIONS FOR TARGETED DELIVERY OF A BIOLOGICALLY ACTIVE SUBSTANCE (SUBSTANCES) AND METHOD OF MANUFACTURING THE SAME
EP2380604A1 (en) * 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
EP2380605A1 (en) * 2010-04-19 2011-10-26 InnoRa Gmbh Improved formulations for drug-coated medical devices
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Also Published As

Publication number Publication date
KR20140121819A (ko) 2014-10-16
SG11201402654TA (en) 2014-09-26
US9233191B2 (en) 2016-01-12
CN104010671A (zh) 2014-08-27
CA2857410A1 (en) 2013-06-27
MX360002B (es) 2018-10-18
AU2012358032A1 (en) 2014-06-12
AU2012358032B2 (en) 2015-09-17
KR101943143B1 (ko) 2019-01-28
JP2015502225A (ja) 2015-01-22
JP6174038B2 (ja) 2017-08-02
CA2857410C (en) 2019-01-08
EP2793967A1 (en) 2014-10-29
WO2013092416A1 (en) 2013-06-27
CN104010671B (zh) 2016-05-04
ES2550350T3 (es) 2015-11-06
BR112014014814A8 (pt) 2017-06-13
WO2013091722A1 (en) 2013-06-27
MX2014006898A (es) 2014-09-04
EP2793967B1 (en) 2015-08-26
US20140322291A1 (en) 2014-10-30
BR112014014814B1 (pt) 2020-04-22

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06T Formal requirements before examination
B07A Technical examination (opinion): publication of technical examination (opinion)
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law
B09A Decision: intention to grant
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/12/2012, OBSERVADAS AS CONDICOES LEGAIS.