BR112015022047A8 - uso de uma composição compreendendo nanopartículas contendo um fármaco da família limo e uma albumina - Google Patents

uso de uma composição compreendendo nanopartículas contendo um fármaco da família limo e uma albumina Download PDF

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Publication number
BR112015022047A8
BR112015022047A8 BR112015022047A BR112015022047A BR112015022047A8 BR 112015022047 A8 BR112015022047 A8 BR 112015022047A8 BR 112015022047 A BR112015022047 A BR 112015022047A BR 112015022047 A BR112015022047 A BR 112015022047A BR 112015022047 A8 BR112015022047 A8 BR 112015022047A8
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BR
Brazil
Prior art keywords
albumin
composition
nanoparticles containing
limo
bladder cancer
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BR112015022047A
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English (en)
Other versions
BR112015022047A2 (pt
Inventor
P Desai Neil
Original Assignee
Abraxis Bioscience Llc
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Publication date
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of BR112015022047A2 publication Critical patent/BR112015022047A2/pt
Publication of BR112015022047A8 publication Critical patent/BR112015022047A8/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer

Abstract

resumo patente de invenção: "métodos para tratar câncer de bexiga". a presente invenção refere-se a métodos e composições para tratar câncer de bexiga, inclusive de câncer de bexiga metastático e câncer de bexiga não músculo invasivo, pela administração de uma composição compreendendo nanopartículas que contêm inibidor de mtor e opcionalmente uma albumina.
BR112015022047A 2013-03-14 2014-03-13 uso de uma composição compreendendo nanopartículas contendo um fármaco da família limo e uma albumina BR112015022047A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361786175P 2013-03-14 2013-03-14
US201361786167P 2013-03-14 2013-03-14
PCT/US2014/026564 WO2014151853A1 (en) 2013-03-14 2014-03-13 Methods of treating bladder cancer

Publications (2)

Publication Number Publication Date
BR112015022047A2 BR112015022047A2 (pt) 2017-07-18
BR112015022047A8 true BR112015022047A8 (pt) 2019-12-10

Family

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Application Number Title Priority Date Filing Date
BR112015022047A BR112015022047A8 (pt) 2013-03-14 2014-03-13 uso de uma composição compreendendo nanopartículas contendo um fármaco da família limo e uma albumina

Country Status (17)

Country Link
US (3) US9962373B2 (pt)
EP (1) EP2968191B1 (pt)
JP (3) JP6309610B2 (pt)
KR (1) KR20150127187A (pt)
CN (2) CN110934852A (pt)
AU (2) AU2014236802B2 (pt)
BR (1) BR112015022047A8 (pt)
CA (1) CA2903548A1 (pt)
ES (1) ES2881851T3 (pt)
HK (1) HK1220405A1 (pt)
IL (2) IL240983B (pt)
MX (1) MX2015011753A (pt)
NZ (1) NZ630213A (pt)
RU (1) RU2015143490A (pt)
SG (1) SG11201507234UA (pt)
WO (1) WO2014151853A1 (pt)
ZA (1) ZA201506877B (pt)

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Publication number Publication date
NZ630213A (en) 2017-05-26
US9962373B2 (en) 2018-05-08
IL273856A (en) 2020-05-31
US20160008330A1 (en) 2016-01-14
EP2968191B1 (en) 2021-06-16
ZA201506877B (en) 2017-11-29
RU2015143490A3 (pt) 2018-03-13
AU2019201640A1 (en) 2019-04-04
JP6309610B2 (ja) 2018-04-11
JP2016513657A (ja) 2016-05-16
WO2014151853A1 (en) 2014-09-25
US20180214425A1 (en) 2018-08-02
EP2968191A1 (en) 2016-01-20
IL240983B (en) 2020-04-30
BR112015022047A2 (pt) 2017-07-18
JP2018062531A (ja) 2018-04-19
AU2014236802B2 (en) 2019-01-03
SG11201507234UA (en) 2015-10-29
CN105246468A (zh) 2016-01-13
US10413531B2 (en) 2019-09-17
MX2015011753A (es) 2015-12-07
ES2881851T3 (es) 2021-11-30
IL240983A0 (en) 2015-11-30
EP2968191A4 (en) 2016-11-16
KR20150127187A (ko) 2015-11-16
RU2015143490A (ru) 2017-04-26
AU2014236802A1 (en) 2015-09-24
US20200138793A1 (en) 2020-05-07
HK1220405A1 (zh) 2017-05-05
CN110934852A (zh) 2020-03-31
CA2903548A1 (en) 2014-09-25
JP2020050680A (ja) 2020-04-02

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