BR112014014412A2 - nanopartículas compreendendo materiais metálicos e de óxido de háfnio, sua preparação e uso - Google Patents
nanopartículas compreendendo materiais metálicos e de óxido de háfnio, sua preparação e usoInfo
- Publication number
- BR112014014412A2 BR112014014412A2 BR112014014412A BR112014014412A BR112014014412A2 BR 112014014412 A2 BR112014014412 A2 BR 112014014412A2 BR 112014014412 A BR112014014412 A BR 112014014412A BR 112014014412 A BR112014014412 A BR 112014014412A BR 112014014412 A2 BR112014014412 A2 BR 112014014412A2
- Authority
- BR
- Brazil
- Prior art keywords
- nanoparticles
- hafnium oxide
- preparation
- metal
- metallic
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/242—Gold; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Powder Metallurgy (AREA)
Abstract
1/1 resumo nanopartículas compreendendo materiais metálicos e de óxido de háfnio, sua preparação e uso a presente invenção refere-se a novas nanopartículas que podem ser vantajosamente utilizadas no setor de saúde como agentes de diagnóstico e/ou terapêuticos. as nanopartículas da invenção compreendem um material metálico pelo menos parcialmente coberto com um material de óxido de háfnio ou nele incorporado. quando comparado com os produtos existentes, essas nanopartículas oferecem uma vantagem notável sobre relação de risco. especificamente, essas nanopartículas potenciam a eficiência das nanopartículas metálicas conhecidas. de fato, elas retêm as propriedades intrínsecas de metal e são agora além do que utilizáveis com segurança em um mamífero, em particular em um ser humano. a invenção também se refere aos métodos para a produção de ditas nanopartículas, às composições contendo-as, e ao seu uso.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161576437P | 2011-12-16 | 2011-12-16 | |
EP11193968 | 2011-12-16 | ||
PCT/EP2012/075731 WO2013087920A1 (en) | 2011-12-16 | 2012-12-17 | Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014014412A2 true BR112014014412A2 (pt) | 2017-06-13 |
Family
ID=48611880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014014412A BR112014014412A2 (pt) | 2011-12-16 | 2012-12-17 | nanopartículas compreendendo materiais metálicos e de óxido de háfnio, sua preparação e uso |
Country Status (16)
Country | Link |
---|---|
US (1) | US10945965B2 (pt) |
EP (1) | EP2790682B1 (pt) |
JP (1) | JP6042450B2 (pt) |
KR (1) | KR102025743B1 (pt) |
CN (1) | CN104093401B (pt) |
AU (1) | AU2012351537B2 (pt) |
BR (1) | BR112014014412A2 (pt) |
CA (1) | CA2857260C (pt) |
EA (1) | EA029635B1 (pt) |
HK (1) | HK1203353A1 (pt) |
IL (1) | IL233035B (pt) |
MA (1) | MA35851B1 (pt) |
MX (1) | MX362089B (pt) |
PL (1) | PL2790682T3 (pt) |
SG (1) | SG11201403096VA (pt) |
WO (1) | WO2013087920A1 (pt) |
Families Citing this family (16)
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EP2729180B1 (en) | 2011-07-08 | 2019-01-23 | The University of North Carolina At Chapel Hill | Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders |
WO2013087920A1 (en) | 2011-12-16 | 2013-06-20 | Nanobiotix | Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof |
PL2948179T3 (pl) | 2013-01-25 | 2019-10-31 | Nanobiotix | Kompozycje zawierające nanocząstki tlenku hafnu(iv) lub tlenku renu(iv) w połączeniu z promieniowaniem jonizującym do leczenia nowotworu |
JP6560665B2 (ja) * | 2013-06-20 | 2019-08-14 | ナノビオティックスNanobiotix | 医療診断に使用するための組成物および方法 |
EP3206987B2 (en) | 2014-10-14 | 2024-07-24 | The University of Chicago | Nanoparticles for photodynamic therapy, x-ray induced photodynamic therapy, radiotherapy, chemotherapy, immunotherapy, and any combination thereof |
US10806694B2 (en) * | 2014-10-14 | 2020-10-20 | The University Of Chicago | Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof |
CN107708668A (zh) * | 2015-05-28 | 2018-02-16 | 纳米生物技术公司 | 用作治疗性疫苗的纳米粒子 |
US11389536B2 (en) * | 2015-07-17 | 2022-07-19 | BioCurity Pharmaceuticals Inc. | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent |
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EP3439666A4 (en) | 2016-05-20 | 2019-12-11 | The University of Chicago | NANOPARTICLES FOR CHEMOTHERAPY, TARGETED THERAPY, PHOTODYNAMIC THERAPY, IMMUNOTHERAPY AND ANY COMBINATION THEREOF |
US11278723B2 (en) * | 2016-12-21 | 2022-03-22 | Nanobiotix S.A. | Nanoparticles for use for treating a neuronal disorder |
WO2019028250A1 (en) | 2017-08-02 | 2019-02-07 | The University Of Chicago | NOMOGENEOUS ORGANOMETALLIC ORGANOMETRIC ORGANOMETRIC LAYERS FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RODIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF |
JP7116563B2 (ja) * | 2018-03-16 | 2022-08-10 | 株式会社日本触媒 | 複合粒子 |
CN109010828B (zh) * | 2018-10-12 | 2020-10-20 | 中国科学院高能物理研究所 | 一种二硫化钼/二氧化铪的复合纳米材料、其制备方法及用途 |
CN112675305B (zh) * | 2021-01-22 | 2023-05-23 | 中国科学院深圳先进技术研究院 | 用于肿瘤治疗的双亲性分子自组装纳米药物及制备方法和用途 |
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2012
- 2012-12-17 WO PCT/EP2012/075731 patent/WO2013087920A1/en active Application Filing
- 2012-12-17 CN CN201280062223.XA patent/CN104093401B/zh active Active
- 2012-12-17 AU AU2012351537A patent/AU2012351537B2/en active Active
- 2012-12-17 JP JP2014546562A patent/JP6042450B2/ja active Active
- 2012-12-17 EP EP12806026.6A patent/EP2790682B1/en active Active
- 2012-12-17 EA EA201491199A patent/EA029635B1/ru not_active IP Right Cessation
- 2012-12-17 SG SG11201403096VA patent/SG11201403096VA/en unknown
- 2012-12-17 US US14/364,859 patent/US10945965B2/en active Active
- 2012-12-17 CA CA2857260A patent/CA2857260C/en active Active
- 2012-12-17 BR BR112014014412A patent/BR112014014412A2/pt not_active Application Discontinuation
- 2012-12-17 KR KR1020147019571A patent/KR102025743B1/ko active IP Right Grant
- 2012-12-17 MX MX2014007131A patent/MX362089B/es active IP Right Grant
- 2012-12-17 PL PL12806026T patent/PL2790682T3/pl unknown
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2014
- 2014-06-09 IL IL233035A patent/IL233035B/en active IP Right Grant
- 2014-07-09 MA MA37185A patent/MA35851B1/fr unknown
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2015
- 2015-04-15 HK HK15103694.6A patent/HK1203353A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU2012351537B2 (en) | 2017-03-02 |
MX362089B (es) | 2019-01-07 |
MA35851B1 (fr) | 2014-12-01 |
EA201491199A1 (ru) | 2014-11-28 |
CA2857260C (en) | 2019-10-15 |
EP2790682A1 (en) | 2014-10-22 |
CN104093401A (zh) | 2014-10-08 |
JP2015509079A (ja) | 2015-03-26 |
KR20140108685A (ko) | 2014-09-12 |
HK1203353A1 (en) | 2015-10-30 |
JP6042450B2 (ja) | 2016-12-14 |
MX2014007131A (es) | 2014-09-04 |
NZ625848A (en) | 2015-04-24 |
PL2790682T3 (pl) | 2019-08-30 |
US10945965B2 (en) | 2021-03-16 |
US20140335015A1 (en) | 2014-11-13 |
CN104093401B (zh) | 2018-06-29 |
EP2790682B1 (en) | 2019-03-20 |
CA2857260A1 (en) | 2013-06-20 |
KR102025743B1 (ko) | 2019-09-26 |
WO2013087920A1 (en) | 2013-06-20 |
EA029635B1 (ru) | 2018-04-30 |
AU2012351537A1 (en) | 2014-07-24 |
IL233035B (en) | 2018-02-28 |
IL233035A0 (en) | 2014-07-31 |
SG11201403096VA (en) | 2014-07-30 |
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