BR112014012972A2 - composição de meio de cultura para rejuvenscer células-tronco - Google Patents

composição de meio de cultura para rejuvenscer células-tronco

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Publication number
BR112014012972A2
BR112014012972A2 BR112014012972A BR112014012972A BR112014012972A2 BR 112014012972 A2 BR112014012972 A2 BR 112014012972A2 BR 112014012972 A BR112014012972 A BR 112014012972A BR 112014012972 A BR112014012972 A BR 112014012972A BR 112014012972 A2 BR112014012972 A2 BR 112014012972A2
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Prior art keywords
stem cells
culture medium
medium composition
composition
older person
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BR112014012972A
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English (en)
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Young Lee Hang
Geun Park Hyeong
Chan Ra Jeong
Keun Kang Sung
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K-Stemcell Co Ltd
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Publication date
Application filed by K-Stemcell Co Ltd filed Critical K-Stemcell Co Ltd
Publication of BR112014012972A2 publication Critical patent/BR112014012972A2/pt

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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
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  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

resumo composição de meio de cultura para rejuvenscer células-tronco, refere-se a uma composição de meio de cultura para transformar células-tronco de uma pessoa mais velha em células-tronco mais jovens, e mais particularmente a uma composição de meio de cultura para cultivar células-tronco, que é usado para rejuvenescer células-tronco de uma pessoa mais velha de modo a ter características semelhantes às das células-tronco de pessoas jovens, e a um método para rejuvenescer células-tronco, que compreende cultivar células-tronco de uma pessoa mais velha na composição de meio de cultura. de acordo com a presente invenção, embora células-tronco mesenquimais coletadas de pacientes com mais de 60 anos de idade podem ser transformadas em células-tronco mesenquimais jovens contendo capacidade de diferenciação, alta atividade de telomerase, e capacidade alta para expressar os marcadores de célula-tronco. assim, a presente invenção pode significativamente aumentar a eficácia da terapia celular empregando células-tronco mesenquimais. 1/1
BR112014012972A 2011-12-01 2012-12-03 composição de meio de cultura para rejuvenscer células-tronco BR112014012972A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20110127885 2011-12-01
PCT/KR2012/010380 WO2013081436A1 (ko) 2011-12-01 2012-12-03 줄기세포를 젊게 만들기 위한 배지 조성물

Publications (1)

Publication Number Publication Date
BR112014012972A2 true BR112014012972A2 (pt) 2017-06-13

Family

ID=48535804

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014012972A BR112014012972A2 (pt) 2011-12-01 2012-12-03 composição de meio de cultura para rejuvenscer células-tronco

Country Status (11)

Country Link
US (1) US9708584B2 (pt)
EP (1) EP2811015B1 (pt)
JP (1) JP5968458B2 (pt)
KR (2) KR20130061658A (pt)
CN (1) CN104114691B (pt)
AU (1) AU2012346645B2 (pt)
BR (1) BR112014012972A2 (pt)
CA (1) CA2856764C (pt)
ES (1) ES2827207T3 (pt)
PH (1) PH12014501175A1 (pt)
WO (1) WO2013081436A1 (pt)

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CA2944703C (en) 2014-04-11 2023-09-19 The Administrators Of The Tulane Educational Fund Cell-surface marker of early msc aging
US20160000698A1 (en) * 2014-07-07 2016-01-07 Medipost Co., Ltd. Capability of small-sized stem cells to stimulate hair growth and use thereof
EP3184627B1 (en) * 2014-08-21 2020-12-23 Ajinomoto Co., Inc. Culture medium for mesenchymal stem cells
KR102048067B1 (ko) * 2015-01-19 2019-11-22 서울대학교병원 인간 중간엽 줄기세포의 줄기세포능을 증가시키는 방법
CN104611295A (zh) * 2015-02-06 2015-05-13 华南农业大学 一种食蟹猴睾丸间质祖细胞永生系的建立方法
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WO2017172691A1 (en) * 2016-03-30 2017-10-05 University Of Pittsburgh-Of The Commonwealth System Of Higher Education System for portable gas storage and delivery
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WO2019208688A1 (ja) 2018-04-25 2019-10-31 北海道公立大学法人札幌医科大学 生体移植用細胞シート及びその製造方法
CN113801836A (zh) * 2020-06-16 2021-12-17 台湾粒线体应用技术股份有限公司 提升线粒体功能的培养方法及其使用的组合物
CN112881113B (zh) * 2021-01-12 2023-06-16 武汉呵尔医疗科技发展有限公司 一种稳定的粘液处理剂
CN113583937B (zh) * 2021-07-02 2023-02-10 深圳市北科生物科技有限公司 用于哺乳动物多能干细胞分化成定型内胚层细胞的培养基和培养方法
WO2023200363A1 (ru) * 2022-04-13 2023-10-19 Фания Иршатовна МАГАНОВА Способ получения пероральной формы субстанции, содержащей инсулин
CN115747151B (zh) * 2022-11-25 2024-06-21 南开大学 一种通过调控端粒以稳定扩增脂肪干细胞的方法

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KR101523040B1 (ko) * 2012-06-26 2015-05-26 라정찬 고농도의 줄기세포 제조방법

Also Published As

Publication number Publication date
KR20150093645A (ko) 2015-08-18
EP2811015B1 (en) 2020-09-02
WO2013081436A1 (ko) 2013-06-06
KR20130061658A (ko) 2013-06-11
JP2015500018A (ja) 2015-01-05
ES2827207T3 (es) 2021-05-20
CN104114691B (zh) 2017-05-03
JP5968458B2 (ja) 2016-08-10
PH12014501175B1 (en) 2014-10-20
US9708584B2 (en) 2017-07-18
PH12014501175A1 (en) 2014-10-20
CA2856764A1 (en) 2013-06-06
EP2811015A1 (en) 2014-12-10
CA2856764C (en) 2018-04-03
CN104114691A (zh) 2014-10-22
KR101598813B1 (ko) 2016-03-02
AU2012346645A1 (en) 2014-06-26
EP2811015A4 (en) 2015-01-21
US20140322811A1 (en) 2014-10-30
AU2012346645B2 (en) 2015-08-27

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