BR112014011937A2 - detecção altamente multiplexada quantitativa de ácidos nucléicos - Google Patents
detecção altamente multiplexada quantitativa de ácidos nucléicosInfo
- Publication number
- BR112014011937A2 BR112014011937A2 BR112014011937A BR112014011937A BR112014011937A2 BR 112014011937 A2 BR112014011937 A2 BR 112014011937A2 BR 112014011937 A BR112014011937 A BR 112014011937A BR 112014011937 A BR112014011937 A BR 112014011937A BR 112014011937 A2 BR112014011937 A2 BR 112014011937A2
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- highly multiplexed
- acid detection
- methods
- multiplexed nucleic
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 230000000712 assembly Effects 0.000 abstract 1
- 238000000429 assembly Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161561198P | 2011-11-17 | 2011-11-17 | |
| US13/399,872 US20120214686A1 (en) | 2011-02-18 | 2012-02-17 | Quantitative, Highly Multiplexed Detection of Nucleic Acids |
| PCT/US2012/025699 WO2012112925A2 (en) | 2011-02-18 | 2012-02-17 | Quantitative, highly multiplexed detection of nucleic acids |
| PCT/US2012/051236 WO2013074163A1 (en) | 2011-11-17 | 2012-08-16 | Quantitative, highly multiplexed detection of nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014011937A2 true BR112014011937A2 (pt) | 2017-05-30 |
Family
ID=48430026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014011937A BR112014011937A2 (pt) | 2011-11-17 | 2012-08-16 | detecção altamente multiplexada quantitativa de ácidos nucléicos |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2780479A4 (enExample) |
| JP (1) | JP2014533502A (enExample) |
| KR (1) | KR20140094007A (enExample) |
| CN (1) | CN104093857A (enExample) |
| AU (1) | AU2012337389A1 (enExample) |
| BR (1) | BR112014011937A2 (enExample) |
| CA (1) | CA2855953A1 (enExample) |
| HK (1) | HK1199746A1 (enExample) |
| IL (1) | IL232586A0 (enExample) |
| MX (1) | MX338076B (enExample) |
| SG (1) | SG11201402341QA (enExample) |
| WO (1) | WO2013074163A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015008985A1 (en) * | 2013-07-15 | 2015-01-22 | Seegene, Inc. | Detection of target nucleic acid sequence by pto cleavage and extension-dependent immobilized oligonucleotide hybridization |
| CN107735403B (zh) * | 2015-04-16 | 2021-06-11 | 威廉马歇莱思大学 | 由辅助寡核苷酸物质对核酸杂交探针的化学计量调节 |
| CN110016500A (zh) * | 2018-01-10 | 2019-07-16 | 深圳闪量科技有限公司 | 表面探针定量pcr方法 |
| AU2020388573A1 (en) * | 2019-11-21 | 2022-06-23 | 10X Genomics, Inc, | Spatial analysis of analytes |
| CN111808989A (zh) * | 2020-06-18 | 2020-10-23 | 重庆浦洛通基因医学研究院有限公司 | 一种冠状病毒/流感病毒/鼻病毒核酸联合检测试剂盒及使用方法 |
| EP4442838A3 (en) * | 2020-10-15 | 2024-12-25 | Genentech, Inc. | Multiplexed target-binding candidate screening analysis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422253A (en) * | 1992-12-07 | 1995-06-06 | Wisconsin Alumni Research Foundation | Method of site specific nucleic acid cleavage |
| US6350580B1 (en) * | 2000-10-11 | 2002-02-26 | Stratagene | Methods for detection of a target nucleic acid using a probe comprising secondary structure |
| AU2002363628A1 (en) * | 2001-07-17 | 2003-05-26 | Stratagene | Methods for detection of a target nucleic acid by capture using multi-subunit probes |
| WO2005010199A2 (en) * | 2003-07-16 | 2005-02-03 | Geneohm Sciences, Inc. | Invasive cleavage reaction with electrochemical readout |
| WO2005068660A1 (en) * | 2003-12-19 | 2005-07-28 | Beckman Coulter, Inc. | Solid-phase multiplexed invader assay |
| CA2672246A1 (en) * | 2006-06-30 | 2008-03-13 | Rosetta Genomics Ltd | Detecting nucleic acids |
| EP2118310B1 (en) * | 2006-12-29 | 2013-03-06 | Applied Biosystems, LLC | Systems and methods for detecting nucleic acids |
| EP2077336A1 (en) * | 2007-12-19 | 2009-07-08 | Koninklijke Philips Electronics N.V. | Device and method for parallel quantitative analysis of multiple nucleic acids |
| CN102224257A (zh) * | 2008-11-21 | 2011-10-19 | 皇家飞利浦电子股份有限公司 | 使用双链核酸特异性染料在固体表面上的实时多重pcr检测 |
-
2012
- 2012-08-16 SG SG11201402341QA patent/SG11201402341QA/en unknown
- 2012-08-16 BR BR112014011937A patent/BR112014011937A2/pt not_active IP Right Cessation
- 2012-08-16 KR KR1020147016411A patent/KR20140094007A/ko not_active Withdrawn
- 2012-08-16 WO PCT/US2012/051236 patent/WO2013074163A1/en not_active Ceased
- 2012-08-16 CN CN201280067273.7A patent/CN104093857A/zh active Pending
- 2012-08-16 CA CA2855953A patent/CA2855953A1/en not_active Abandoned
- 2012-08-16 MX MX2014005912A patent/MX338076B/es active IP Right Grant
- 2012-08-16 HK HK15100214.3A patent/HK1199746A1/xx unknown
- 2012-08-16 AU AU2012337389A patent/AU2012337389A1/en not_active Abandoned
- 2012-08-16 EP EP12849697.3A patent/EP2780479A4/en not_active Withdrawn
- 2012-08-16 JP JP2014542300A patent/JP2014533502A/ja active Pending
-
2014
- 2014-05-13 IL IL232586A patent/IL232586A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104093857A (zh) | 2014-10-08 |
| SG11201402341QA (en) | 2014-06-27 |
| KR20140094007A (ko) | 2014-07-29 |
| WO2013074163A1 (en) | 2013-05-23 |
| HK1199746A1 (en) | 2015-07-17 |
| JP2014533502A (ja) | 2014-12-15 |
| EP2780479A4 (en) | 2015-04-08 |
| IL232586A0 (en) | 2014-06-30 |
| EP2780479A1 (en) | 2014-09-24 |
| MX338076B (es) | 2016-04-01 |
| AU2012337389A1 (en) | 2014-06-19 |
| MX2014005912A (es) | 2014-09-04 |
| CA2855953A1 (en) | 2013-05-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112013021144A2 (pt) | detecção quantitativa altamente multiplexada de ácidos nucléicos | |
| IN2014DN04645A (enExample) | ||
| BR112014011937A2 (pt) | detecção altamente multiplexada quantitativa de ácidos nucléicos | |
| MX356986B (es) | Metodo para detectar aductos de nucleosomas. | |
| BR112013007862A2 (pt) | ácidos nucleicos manipulados e métodos de uso dos mesmos. | |
| GB201317477D0 (en) | Methods, compositions and kits for determing the presence/absnece of a variant nucleic acid sequence | |
| BR112016008970A2 (pt) | Método de ativação ex vivo e para avaliar ativação plasmática em um indivíduo, ensaio ex vivo para determinar atividade de calicreína plasmática em uma amostra | |
| DK2572004T3 (da) | Detection of target nucleic acid sequences by pto cleavage and extension assay | |
| BR112013030529A8 (pt) | Método para determinar a presença, ausência ou características de um analito, método e aparelho para sequenciamento de um analito que é um polinucleotídeo alvo, e, kit | |
| CR20140161A (es) | Benzilindazoles sustituidos para uso como inhibidores de la quinasa bub1 en el tratamiento de enfermedades hiperproliferativas | |
| GT201400034A (es) | Compuestos y composiciones como inhibidores de la quinasa c-kit | |
| GB201305223D0 (en) | Reflection detection type measurement apparatus for skin autofluorescence | |
| CL2014003110A1 (es) | Anticuerpo anti-fcrn; secuencias que lo codifican; vector; célula huésped; proceso de producción; composición farmacéutica que lo comprende; uso para el tratamiento de enfermedad autoinmune; y ensayo para probar la capacidad de un anticuerpo para bloquear la actividad de fcrn humano. | |
| BR112012033760A2 (pt) | detecção não invasiva de anormalidades genéticas fetais | |
| BR112015013710A2 (pt) | sistema de ensaio, método para detectar a ligação de um agente bioativo a um alvo celular, célula e método para detectar uma interação entre um agente bioativo e um alvo celular | |
| BR112012011528A2 (pt) | métodos para inibir uma proteína quinase e para tratar uma doença associada com atividade de quinase, e, composto | |
| BR112018069849A2 (pt) | kit, dispositivo e método para a detecção de câncer pancreático precoce ou de lesão precursora do câncer pancreático | |
| DK3578659T3 (da) | Kunstige nukelinsyremolekyler til forbedret protein- eller peptidekspression | |
| BR112015009636A8 (pt) | composto, métodos para o tratamento de um hospedeiro infectado, métodos para a prevenção de uma infecção, métodos para a redução da atividade biológica de uma infecção e uso de um composto | |
| CL2011002943A1 (es) | Anticuerpo triespecifico o tetraespecifico; metodo para la preparacion de dicho anticuerpo; celula huesped; composicion farmaceutica. | |
| IN2015DN02479A (enExample) | ||
| BR122020012978A8 (pt) | Método de quantificação de um produto específico em uma reação de amplificação por corte e extensão (near) | |
| CL2014000490A1 (es) | Compuestos derivados de pirazol y sus sales, con actividad inhibidora de sglt1; composicion farmaceutica que los comprende; y su uso para tratar o prevenir diabetes. | |
| ZA201405894B (en) | Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay | |
| EP2829882B8 (en) | Chip for analysis of target substance |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |