BR112014004635A2 - sistema terapêutico transdérmico para cloridrato de ácido 5-aminolavulínico - Google Patents

sistema terapêutico transdérmico para cloridrato de ácido 5-aminolavulínico

Info

Publication number
BR112014004635A2
BR112014004635A2 BR112014004635A BR112014004635A BR112014004635A2 BR 112014004635 A2 BR112014004635 A2 BR 112014004635A2 BR 112014004635 A BR112014004635 A BR 112014004635A BR 112014004635 A BR112014004635 A BR 112014004635A BR 112014004635 A2 BR112014004635 A2 BR 112014004635A2
Authority
BR
Brazil
Prior art keywords
therapeutic system
transdermal therapeutic
acid hydrochloride
active substance
aminolavulinic
Prior art date
Application number
BR112014004635A
Other languages
English (en)
Other versions
BR112014004635B1 (pt
Inventor
Hoffmann Gerd
Horstmann Michael
Jung Tobias
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of BR112014004635A2 publication Critical patent/BR112014004635A2/pt
Publication of BR112014004635B1 publication Critical patent/BR112014004635B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

resumo patente de invencão: "sistema terapêutico transdérmico para cloridrato de ácido 5-aminolavulínico". a presente invenção refere-se a um sistema terapêutico transdérmico compreendendo uma camada de fundo impermeável à substância ativa, uma matriz polimérica contendo substância ativa e uma camada protetora removível, sendo que como substância ativa é empregada cloridrato do ácido 5-aminolavulínico e o polímero básico da matriz polimérica é um poliacrilato aderente. o sistema terapêutico transdérmico descrito é adequado para o diagnóstico e tratamento de pré-estágios de câncer epidérmico, como ceratose actínica, e enfermidades epidérmicas oncológicas. 20617180v1
BR112014004635-2A 2011-08-31 2012-08-24 Sistema terapêutico transdérmico para cloridrato de ácido 5-aminolevulínico e seu uso BR112014004635B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102011111865.2 2011-08-31
DE102011111865A DE102011111865A1 (de) 2011-08-31 2011-08-31 Transdermales therapeutisches System für 5-Aminolävulinsäurehydrochlorid
PCT/EP2012/066541 WO2013030129A1 (de) 2011-08-31 2012-08-24 Transdermales therapeutisches system für 5-aminolävulinsäurehydrochlorid

Publications (2)

Publication Number Publication Date
BR112014004635A2 true BR112014004635A2 (pt) 2017-03-14
BR112014004635B1 BR112014004635B1 (pt) 2022-09-13

Family

ID=46724447

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014004635-2A BR112014004635B1 (pt) 2011-08-31 2012-08-24 Sistema terapêutico transdérmico para cloridrato de ácido 5-aminolevulínico e seu uso

Country Status (17)

Country Link
US (2) US10307382B2 (pt)
EP (1) EP2750673B1 (pt)
JP (2) JP6035335B2 (pt)
KR (1) KR101933610B1 (pt)
CN (1) CN103764135B (pt)
AU (1) AU2012301042B2 (pt)
BR (1) BR112014004635B1 (pt)
CA (1) CA2844288C (pt)
DE (1) DE102011111865A1 (pt)
DK (1) DK2750673T3 (pt)
ES (1) ES2646737T3 (pt)
MX (1) MX351514B (pt)
NO (1) NO2750673T3 (pt)
PL (1) PL2750673T3 (pt)
PT (1) PT2750673T (pt)
RU (1) RU2607657C2 (pt)
WO (1) WO2013030129A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9179844B2 (en) 2011-11-28 2015-11-10 Aranz Healthcare Limited Handheld skin measuring or monitoring device
CZ307444B6 (cs) * 2015-04-22 2018-08-29 Jakub Rak Mukoadhezivní polymerní film pro fotosenzitivní terapii v ústní dutině s obsahem fotosenzitizérů
US10013527B2 (en) 2016-05-02 2018-07-03 Aranz Healthcare Limited Automatically assessing an anatomical surface feature and securely managing information related to the same
US11116407B2 (en) 2016-11-17 2021-09-14 Aranz Healthcare Limited Anatomical surface assessment methods, devices and systems
EP3606410B1 (en) 2017-04-04 2022-11-02 Aranz Healthcare Limited Anatomical surface assessment methods, devices and systems
KR102171200B1 (ko) 2018-11-20 2020-10-28 제너럴바이오(주) 5-아미노레불린산 수화염화물과 그 유도체를 유효성분으로 함유하는 여드름성 피부염 개선 또는 그의 조성물
CN111517973B (zh) * 2019-02-02 2023-08-04 中国科学院天津工业生物技术研究所 一种从发酵液中制备5-氨基乙酰丙酸盐酸盐的生产工艺及其应用

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
WO1996006602A1 (en) * 1993-08-27 1996-03-07 Noven Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR THE ADMINISTRATION OF δ-AMINOLEVULINIC ACID AND PHARMACEUTICAL EQUIVALENTS THEREOF
GR1002807B (el) 1996-06-20 1997-11-13 Lavipharm A.E. Συστημα για την τοπικη θεραπεια της ακμης και μεθοδος παραγωγης του
HU0200901D0 (pt) 1996-06-20 2002-08-28 Lavipharm Sa
US5856566A (en) 1997-09-02 1999-01-05 Dusa Pharmaceuticals, Inc. Sterilized 5-aminolevulinic acid
ES2237415T5 (es) * 1999-01-14 2008-12-16 Noven Pharmaceuticals, Inc. Composiciones dermicas.
DE10034673C1 (de) * 2000-07-17 2002-04-25 Medac Klinische Spezialpraep Dermales Applikationssystem für Aminolävulinsäure und seine Verwendung
WO2002013788A1 (en) 2000-08-16 2002-02-21 The General Hospital Corporation D/B/A Massachusetts General Hospital Topical aminolevulinic acid-photodynamic therapy for acne vulgaris
KR100846912B1 (ko) 2001-01-12 2008-07-17 페데랄노에고수다르스트벤노에유니타르노에프레드프리야티에고수다르스트벤니나우쉬니티센트르나우쉬노이슬레도바텔스키인스티튜트오르가니쉐스키크흐포루프로두크토브아이크르아시텔에이에프지업지엔트스니오피크 광에너지 요법 및 그 요법을 수행하기 위한 도포기
KR101028788B1 (ko) * 2001-10-24 2011-04-14 파워 페이퍼 리미티드 피부 내로의 활성 물질의 제어된 전달 장치 및 방법
DE10200578A1 (de) 2002-01-09 2003-07-10 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme
DE10202487A1 (de) 2002-01-23 2003-07-31 Photonamic Gmbh & Co Kg Dermales Applikationssystem für Aminolävulinsäure-Derivate
DE10344334A1 (de) 2003-09-24 2005-04-28 Johann Berger Gewebtes Gurtband
JP5632577B2 (ja) * 2005-01-31 2014-11-26 久光製薬株式会社 貼付剤
US20060182790A1 (en) * 2005-02-17 2006-08-17 Flor Mayoral Dermal medicaments application enhancer
US20100087768A1 (en) * 2008-10-02 2010-04-08 Forlano Paula Transdermal drug delivery system for liquid active ingredient

Also Published As

Publication number Publication date
EP2750673B1 (de) 2017-08-09
CA2844288A1 (en) 2013-03-07
CA2844288C (en) 2019-08-20
KR20140056370A (ko) 2014-05-09
ES2646737T3 (es) 2017-12-15
CN103764135A (zh) 2014-04-30
DE102011111865A1 (de) 2013-02-28
MX2014002215A (es) 2014-04-30
RU2014111255A (ru) 2015-10-10
JP6203364B2 (ja) 2017-09-27
PT2750673T (pt) 2017-11-15
US20140323994A1 (en) 2014-10-30
PL2750673T3 (pl) 2018-11-30
NO2750673T3 (pt) 2018-01-06
JP6035335B2 (ja) 2016-11-30
CN103764135B (zh) 2018-06-22
BR112014004635B1 (pt) 2022-09-13
WO2013030129A1 (de) 2013-03-07
JP2017061489A (ja) 2017-03-30
JP2014527537A (ja) 2014-10-16
DK2750673T3 (da) 2017-11-20
AU2012301042B2 (en) 2017-07-13
RU2607657C2 (ru) 2017-01-10
EP2750673A1 (de) 2014-07-09
US20190240166A1 (en) 2019-08-08
MX351514B (es) 2017-10-17
US10307382B2 (en) 2019-06-04
AU2012301042A1 (en) 2014-03-20
KR101933610B1 (ko) 2018-12-28

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B25A Requested transfer of rights approved

Owner name: LTS LOHMANN THERAPIE-SYSTEME AG (DE) ; PHOTONAMIC GMBH AND CO. KG (DE)

Owner name: LTS LOHMANN THERAPIE-SYSTEME AG (DE) ; PHOTONAMIC

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/08/2012, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.