BR112014002845A2 - composto, sal farmaceuticamente aceitável, composição farmacêutica, e, uso de um composto - Google Patents
composto, sal farmaceuticamente aceitável, composição farmacêutica, e, uso de um compostoInfo
- Publication number
- BR112014002845A2 BR112014002845A2 BR112014002845A BR112014002845A BR112014002845A2 BR 112014002845 A2 BR112014002845 A2 BR 112014002845A2 BR 112014002845 A BR112014002845 A BR 112014002845A BR 112014002845 A BR112014002845 A BR 112014002845A BR 112014002845 A2 BR112014002845 A2 BR 112014002845A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutically acceptable
- pharmaceutical composition
- acceptable salt
- pharmaceutical
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161525440P | 2011-08-19 | 2011-08-19 | |
| US201261650681P | 2012-05-23 | 2012-05-23 | |
| PCT/US2012/050268 WO2013028371A1 (en) | 2011-08-19 | 2012-08-10 | Benzofuran compounds for the treatment of hepatitis c virus infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014002845A2 true BR112014002845A2 (pt) | 2017-02-21 |
Family
ID=47746761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014002845A BR112014002845A2 (pt) | 2011-08-19 | 2012-08-10 | composto, sal farmaceuticamente aceitável, composição farmacêutica, e, uso de um composto |
Country Status (38)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2014001833A (es) * | 2011-08-17 | 2014-02-27 | Glaxosmithkline Llc | Metodos terapeuticos. |
| PH12014500385A1 (en) | 2011-08-19 | 2020-06-22 | Glaxo Group Ltd | Benzofuran compounds for the treatment of hepatitis c virus infections |
| SG11201703645XA (en) * | 2014-11-10 | 2017-06-29 | Glaxosmithkline Intellectual Property (No 2) Ltd | Long acting pharmaceutical compositions for hepatitis c |
| KR20170081257A (ko) * | 2014-11-10 | 2017-07-11 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | C형 간염에 대한 조합 장기 작용 조성물 및 방법 |
| KR20180006522A (ko) | 2016-07-07 | 2018-01-18 | 삼성디스플레이 주식회사 | 액정 조성물 및 이를 포함하는 액정 표시 장치 |
| US11738088B2 (en) | 2016-08-01 | 2023-08-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | Boryl ethers, carbonates, and cyclic acetals as oxidatively-triggered drug delivery vehicles |
| CA3055194A1 (en) * | 2017-03-02 | 2018-09-07 | Assembly Biosciences, Inc. | Cyclic sulfamide compounds and methods of using same |
| CA3088347A1 (en) * | 2018-01-17 | 2019-07-25 | Glaxosmithkline Intellectual Property Development Limited | Pi4kiii.beta. inhibitors |
| EP4049680A4 (en) * | 2019-10-25 | 2024-01-10 | Sumitomo Pharma Co., Ltd. | NEW SUBSTITUTED CONDENSED RING CONNECTION |
| CN111026203B (zh) * | 2019-12-02 | 2021-01-26 | 宁波德晶元科技有限公司 | 一种适用于真空热水壶的加热控制方法与系统 |
| MX2023007150A (es) * | 2020-12-18 | 2023-09-04 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de pirazol que contienen boro, composiciones que los comprenden, métodos y usos de los mismos. |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083903A (en) | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| AU5920400A (en) * | 1999-07-07 | 2001-01-22 | Du Pont Pharmaceuticals Company | Cell-based assay systems for examining hcv ns3 protease activity |
| ES2571219T3 (es) | 2001-01-25 | 2024-09-23 | The United States Of America Represented By The Sec Dep Of Health And Human Services | Formulación de compuestos de ácido borónico |
| EA009943B1 (ru) * | 2002-11-01 | 2008-04-28 | Вирофарма Инкорпорейтед | Соединения бензофурана, композиции и способы лечения и профилактики инфекций, вызванных вирусом гепатита с, и связанных с ним заболеваний |
| AU2006349612A1 (en) | 2005-12-01 | 2008-05-02 | Wyeth | Anthranilic acid derivatives useful in treating infection with Hepatitis C virus |
| PT1988779E (pt) | 2006-02-16 | 2015-09-04 | Anacor Pharmaceuticals Inc | Moléculas pequenas contendo boro como agentes antiinflamatórios |
| EP2015757A4 (en) * | 2006-05-02 | 2011-01-26 | Anacor Pharmaceuticals Inc | HYDROLYSERESISTENT, BOROYED THERAPEUTIC USES |
| US20070286822A1 (en) | 2006-06-12 | 2007-12-13 | Anacor Pharmaceuticals Inc. | Compounds for the Treatment of Periodontal Disease |
| MX2009013332A (es) | 2007-06-08 | 2010-01-25 | Mannkind Corp | Inhibidores de ire-1 alfa. |
| GB0719366D0 (en) * | 2007-10-03 | 2007-11-14 | Smithkline Beecham Corp | Compounds |
| WO2009111676A2 (en) | 2008-03-06 | 2009-09-11 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules as anti-inflammatory agents |
| ATE539070T1 (de) * | 2008-02-14 | 2012-01-15 | Hoffmann La Roche | Heterozyklische antivirale verbindungen |
| WO2009137493A1 (en) | 2008-05-05 | 2009-11-12 | Wyeth | 2-substituted benzofuran compounds to treat infection with hepatitis c virus |
| WO2009137500A1 (en) | 2008-05-05 | 2009-11-12 | Wyeth | 6-substituted benzofuran compounds to treat infection with hepatitis c virus |
| US7737157B2 (en) | 2008-08-29 | 2010-06-15 | Hutchison Medipharma Enterprises Limited | Pyrimidine compounds |
| EP2348863A4 (en) | 2008-09-04 | 2012-03-07 | Anacor Pharmaceuticals Inc | BORN SMALL MOLECULES |
| WO2011050284A1 (en) * | 2009-10-23 | 2011-04-28 | Glaxosmithkline Llc | Pyrazolylpyridine antiviral agents |
| WO2011103063A1 (en) * | 2010-02-19 | 2011-08-25 | Glaxo Group Limited | Therapeutic compounds |
| WO2011106929A1 (en) | 2010-03-02 | 2011-09-09 | Merck Sharp & Dohme Corp. | Inhibitors of hepatitis c virus ns5b polymerase |
| TW201136919A (en) | 2010-03-02 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | Inhibitors of hepatitis C virus NS5B polymerase |
| WO2012067664A1 (en) | 2010-11-18 | 2012-05-24 | Glaxo Group Limited | Compounds |
| AU2011329485A1 (en) | 2010-11-18 | 2013-04-18 | Glaxo Group Limited | Compounds |
| MX2014001833A (es) * | 2011-08-17 | 2014-02-27 | Glaxosmithkline Llc | Metodos terapeuticos. |
| WO2013025975A1 (en) * | 2011-08-17 | 2013-02-21 | Glaxosmithkline Llc | Combination treatments for hepatitis c |
| PH12014500385A1 (en) | 2011-08-19 | 2020-06-22 | Glaxo Group Ltd | Benzofuran compounds for the treatment of hepatitis c virus infections |
-
2012
- 2012-08-10 PH PH1/2014/500385A patent/PH12014500385A1/en unknown
- 2012-08-10 HU HUE12826498A patent/HUE030300T2/en unknown
- 2012-08-10 MX MX2014001989A patent/MX354676B/es active IP Right Grant
- 2012-08-10 PL PL12826498T patent/PL2744332T3/pl unknown
- 2012-08-10 RS RS20161131A patent/RS55462B1/sr unknown
- 2012-08-10 SG SG10201606883QA patent/SG10201606883QA/en unknown
- 2012-08-10 EP EP16195408.6A patent/EP3199531A1/en not_active Withdrawn
- 2012-08-10 ME MEP-2016-287A patent/ME02588B/me unknown
- 2012-08-10 WO PCT/US2012/050268 patent/WO2013028371A1/en not_active Ceased
- 2012-08-10 ES ES12826498.3T patent/ES2611731T3/es active Active
- 2012-08-10 EP EP12826498.3A patent/EP2744332B1/en active Active
- 2012-08-10 IN IN572CHN2014 patent/IN2014CN00572A/en unknown
- 2012-08-10 EA EA201490213A patent/EA032841B1/ru not_active IP Right Cessation
- 2012-08-10 PT PT128264983T patent/PT2744332T/pt unknown
- 2012-08-10 KR KR1020147007196A patent/KR101913800B1/ko not_active Expired - Fee Related
- 2012-08-10 AU AU2012299295A patent/AU2012299295B2/en not_active Ceased
- 2012-08-10 US US13/885,500 patent/US8927593B2/en not_active Expired - Fee Related
- 2012-08-10 HR HRP20161743TT patent/HRP20161743T1/hr unknown
- 2012-08-10 DK DK12826498.3T patent/DK2744332T3/en active
- 2012-08-10 BR BR112014002845A patent/BR112014002845A2/pt not_active Application Discontinuation
- 2012-08-10 CA CA2844086A patent/CA2844086A1/en not_active Abandoned
- 2012-08-10 SM SM20170028T patent/SMT201700028T1/it unknown
- 2012-08-10 LT LTEP12826498.3T patent/LT2744332T/lt unknown
- 2012-08-10 SI SI201230826A patent/SI2744332T1/sl unknown
- 2012-08-10 CN CN201280040219.3A patent/CN103732065B/zh not_active Expired - Fee Related
- 2012-08-10 PE PE2014000197A patent/PE20141201A1/es not_active Application Discontinuation
- 2012-08-10 JP JP2014526090A patent/JP6367712B2/ja not_active Expired - Fee Related
- 2012-08-16 JO JOP/2012/0233A patent/JO3281B1/ar active
- 2012-08-16 AR ARP120103008A patent/AR087563A1/es unknown
- 2012-08-17 TW TW101130017A patent/TWI538915B/zh not_active IP Right Cessation
- 2012-08-17 UY UY0001034274A patent/UY34274A/es not_active Application Discontinuation
-
2014
- 2014-01-16 IL IL230487A patent/IL230487B/en not_active IP Right Cessation
- 2014-01-23 CO CO14013113A patent/CO6862153A2/es active IP Right Grant
- 2014-02-10 ZA ZA201401020A patent/ZA201401020B/en unknown
- 2014-02-17 CL CL2014000393A patent/CL2014000393A1/es unknown
- 2014-02-18 CR CR20140078A patent/CR20140078A/es unknown
- 2014-02-19 DO DO2014000034A patent/DOP2014000034A/es unknown
- 2014-03-13 MA MA36832A patent/MA35443B1/fr unknown
- 2014-11-20 US US14/548,524 patent/US9682999B2/en not_active Expired - Fee Related
-
2016
- 2016-12-22 JP JP2016249387A patent/JP2017125010A/ja active Pending
- 2016-12-27 CY CY20161101345T patent/CY1118399T1/el unknown
-
2017
- 2017-01-18 SM SM201700028T patent/SMT201700028B/it unknown
- 2017-02-03 CL CL2017000293A patent/CL2017000293A1/es unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |