BR112014001423A2 - teste para capturar e detectar células circulantes de mieloma múltiplo no sangue - Google Patents

teste para capturar e detectar células circulantes de mieloma múltiplo no sangue

Info

Publication number
BR112014001423A2
BR112014001423A2 BR112014001423A BR112014001423A BR112014001423A2 BR 112014001423 A2 BR112014001423 A2 BR 112014001423A2 BR 112014001423 A BR112014001423 A BR 112014001423A BR 112014001423 A BR112014001423 A BR 112014001423A BR 112014001423 A2 BR112014001423 A2 BR 112014001423A2
Authority
BR
Brazil
Prior art keywords
multiple myeloma
test
myeloma cells
circulating multiple
blood
Prior art date
Application number
BR112014001423A
Other languages
English (en)
Other versions
BR112014001423B1 (pt
Inventor
Morano Carrie
Chandra Rao Galla
Mata Marielena
Carle Connelly Mark
Gross Steven
Original Assignee
Janssen Diagnostics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Diagnostics Llc filed Critical Janssen Diagnostics Llc
Publication of BR112014001423A2 publication Critical patent/BR112014001423A2/pt
Publication of BR112014001423B1 publication Critical patent/BR112014001423B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57426—Specifically defined cancers leukemia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

abstract the invention includes methods for isolating circulating multiple myeloma cells as well as method of treating patients suspected of having diseases of abnormal plasma cells. ____________________ tradução resumo patente de invenção: "teste para capturar e detectar células circulantes de mieloma múltiplo no sangue" a presente invenção refere-se aos métodos para isolar células circulantes de mieloma múltiplo bem como ao método para tratar pacientes suspeitos de ter doenças de células plasmáticas anormais.
BR112014001423-0A 2011-07-21 2012-07-20 Métodos para capturar, isolar e analisar células circulantes de mieloma múltiplo em uma amostra e para determinar se um paciente é um candidato provável à intervenção terapêutica, bem como uso de partículas magnéticas coloidais e pelo menos dois ligantes BR112014001423B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510170P 2011-07-21 2011-07-21
US61/510,170 2011-07-21
PCT/US2012/047747 WO2013013222A1 (en) 2011-07-21 2012-07-20 Assay to capture and detect circulating multiple myeloma cells from blood

Publications (2)

Publication Number Publication Date
BR112014001423A2 true BR112014001423A2 (pt) 2017-07-18
BR112014001423B1 BR112014001423B1 (pt) 2021-09-21

Family

ID=46584417

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014001423-0A BR112014001423B1 (pt) 2011-07-21 2012-07-20 Métodos para capturar, isolar e analisar células circulantes de mieloma múltiplo em uma amostra e para determinar se um paciente é um candidato provável à intervenção terapêutica, bem como uso de partículas magnéticas coloidais e pelo menos dois ligantes

Country Status (20)

Country Link
US (1) US9618515B2 (pt)
EP (1) EP2734307B1 (pt)
JP (2) JP6301250B2 (pt)
CN (3) CN114460286A (pt)
BR (1) BR112014001423B1 (pt)
CA (1) CA2842679C (pt)
CY (1) CY1123172T1 (pt)
DK (1) DK2734307T3 (pt)
ES (1) ES2799581T3 (pt)
HK (1) HK1259414A1 (pt)
HR (1) HRP20200961T1 (pt)
HU (1) HUE049527T2 (pt)
LT (1) LT2734307T (pt)
MX (1) MX351113B (pt)
PL (1) PL2734307T3 (pt)
PT (1) PT2734307T (pt)
RS (1) RS60783B1 (pt)
SI (1) SI2734307T1 (pt)
TW (2) TWI605122B (pt)
WO (1) WO2013013222A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2799581T3 (es) * 2011-07-21 2020-12-18 Menarini Silicon Biosystems Spa Ensayo para capturar y detectar células de mieloma múltiple circulantes de la sangre
HUE052519T2 (hu) 2013-03-15 2021-05-28 Menarini Silicon Biosystems Spa Keringõ tumorsejtek dúsítása a fehérvérsejtek depletálása által
WO2018160553A1 (en) * 2017-02-28 2018-09-07 Menarini Silicon Biosystems, Inc. Improved kits and assays to detect circulating multiple myeloma cells from blood
US11103351B2 (en) 2017-04-05 2021-08-31 Opus Medical Therapies, LLC Transcatheter atrial sealing skirt and related method
CN110730633B (zh) 2017-04-05 2023-01-20 欧普斯医疗疗法有限公司 经导管的瓣膜、锚固件、系绳的植入组件
US11123187B2 (en) 2017-04-05 2021-09-21 Opus Medical Therapies, LLC Transcatheter atrial anchors and methods of implantation
US11337685B2 (en) 2017-04-05 2022-05-24 Opus Medical Therapies, LLC Transcatheter anchoring assembly for a mitral valve, a mitral valve, and related methods
US10820992B2 (en) 2017-04-05 2020-11-03 Opus Medical Therapies, LLC Transcatheter atrial sealing skirt, anchor, and tether and methods of implantation
CN109991410B (zh) * 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
CN109270262B (zh) * 2018-10-08 2022-05-20 宁波美晶医疗技术有限公司 一种基于微流体技术的激光单细胞提取方法
IL294980A (en) 2020-01-22 2022-09-01 Opus Medical Therapies Llc Support for an infiltrating catheter anchor, catheter devices, systems and methods of application
AU2021351697A1 (en) 2020-10-01 2023-06-08 Opus Medical Therapies, LLC Transcatheter anchor support and methods of implantation
CN112698037B (zh) * 2021-03-25 2021-06-25 北京积水潭医院 一种检测多发性骨髓瘤治疗效果的抗体组合物及其试剂盒和应用
CN116064368A (zh) * 2021-10-29 2023-05-05 京东方科技集团股份有限公司 用于捕获cd138阳性细胞的捕获剂及制备方法、捕获方法

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US5597531A (en) 1985-10-04 1997-01-28 Immunivest Corporation Resuspendable coated magnetic particles and stable magnetic particle suspensions
US5698271A (en) 1989-08-22 1997-12-16 Immunivest Corporation Methods for the manufacture of magnetically responsive particles
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US20110269638A1 (en) * 2011-04-29 2011-11-03 Epstein Joshua Genes associated with post relapse survival and uses thereof
ES2799581T3 (es) * 2011-07-21 2020-12-18 Menarini Silicon Biosystems Spa Ensayo para capturar y detectar células de mieloma múltiple circulantes de la sangre

Also Published As

Publication number Publication date
EP2734307A1 (en) 2014-05-28
WO2013013222A1 (en) 2013-01-24
TW201700975A (zh) 2017-01-01
CN108375676B (zh) 2022-01-07
HUE049527T2 (hu) 2020-09-28
CN108375676A (zh) 2018-08-07
EP2734307B1 (en) 2020-03-25
CN114460286A (zh) 2022-05-10
RS60783B1 (sr) 2020-10-30
CY1123172T1 (el) 2021-10-29
HRP20200961T1 (hr) 2020-10-02
PL2734307T3 (pl) 2020-11-16
JP2018100978A (ja) 2018-06-28
TWI663399B (zh) 2019-06-21
CN103826750A (zh) 2014-05-28
JP2014521107A (ja) 2014-08-25
MX2014000804A (es) 2014-09-04
US9618515B2 (en) 2017-04-11
BR112014001423B1 (pt) 2021-09-21
TW201317352A (zh) 2013-05-01
US20130189675A1 (en) 2013-07-25
HK1259414A1 (zh) 2019-11-29
JP6821619B2 (ja) 2021-01-27
JP6301250B2 (ja) 2018-03-28
LT2734307T (lt) 2020-07-10
CA2842679C (en) 2021-06-29
MX351113B (es) 2017-10-02
CA2842679A1 (en) 2013-01-24
TWI605122B (zh) 2017-11-11
SI2734307T1 (sl) 2020-10-30
ES2799581T3 (es) 2020-12-18
PT2734307T (pt) 2020-06-25
CN103826750B (zh) 2020-11-10
DK2734307T3 (da) 2020-06-02

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/07/2012, OBSERVADAS AS CONDICOES LEGAIS.