BR112013028735A2 - composições estáveis de iodopovidona com esteróides ou anti-inflamatórios não esteróides - Google Patents
composições estáveis de iodopovidona com esteróides ou anti-inflamatórios não esteróidesInfo
- Publication number
- BR112013028735A2 BR112013028735A2 BR112013028735A BR112013028735A BR112013028735A2 BR 112013028735 A2 BR112013028735 A2 BR 112013028735A2 BR 112013028735 A BR112013028735 A BR 112013028735A BR 112013028735 A BR112013028735 A BR 112013028735A BR 112013028735 A2 BR112013028735 A2 BR 112013028735A2
- Authority
- BR
- Brazil
- Prior art keywords
- steroids
- steroidal anti
- retaining members
- inflammatory drugs
- povidone iodine
- Prior art date
Links
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 title 1
- 229920000153 Povidone-iodine Polymers 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 title 1
- 229960001621 povidone-iodine Drugs 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Anesthesiology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161485475P | 2011-05-12 | 2011-05-12 | |
| PCT/US2012/037563 WO2012155062A1 (en) | 2011-05-12 | 2012-05-11 | Stable povidone-iodine compositions with steroids or non-steroidal anti-inflammatories |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013028735A2 true BR112013028735A2 (pt) | 2017-12-05 |
Family
ID=47139697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013028735A BR112013028735A2 (pt) | 2011-05-12 | 2012-05-11 | composições estáveis de iodopovidona com esteróides ou anti-inflamatórios não esteróides |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20150038473A1 (enExample) |
| EP (1) | EP2707006B1 (enExample) |
| JP (2) | JP6072009B2 (enExample) |
| KR (1) | KR101967938B1 (enExample) |
| CN (1) | CN103957922A (enExample) |
| AR (1) | AR086399A1 (enExample) |
| AU (3) | AU2012253335B2 (enExample) |
| BR (1) | BR112013028735A2 (enExample) |
| CA (1) | CA2835343A1 (enExample) |
| CL (1) | CL2013003016A1 (enExample) |
| CO (1) | CO6821949A2 (enExample) |
| EC (1) | ECSP13013069A (enExample) |
| MX (1) | MX360666B (enExample) |
| PE (1) | PE20141070A1 (enExample) |
| TW (2) | TWI717552B (enExample) |
| WO (1) | WO2012155062A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2665195B2 (ja) | 1995-05-19 | 1997-10-22 | 日本電気移動通信株式会社 | Mcaシステムにおける移動局の個別番号表示方法 |
| US7767217B2 (en) * | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| TW201808311A (zh) * | 2011-09-16 | 2018-03-16 | 遠景生物製藥股份有限公司 | 安定之普維酮-碘組成物 |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US9056057B2 (en) | 2012-05-03 | 2015-06-16 | Kala Pharmaceuticals, Inc. | Nanocrystals, compositions, and methods that aid particle transport in mucus |
| EP2844227B1 (en) | 2012-05-03 | 2020-11-18 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| EP2956138B1 (en) | 2013-02-15 | 2022-06-22 | Kala Pharmaceuticals, Inc. | Therapeutic compounds and uses thereof |
| JP6226998B2 (ja) | 2013-02-15 | 2017-11-08 | 千寿製薬株式会社 | 抗菌性金属を含有するジフルプレドナートエマルション組成物 |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| ES2831625T3 (es) | 2013-02-20 | 2021-06-09 | Kala Pharmaceuticals Inc | Compuestos terapéuticos y sus usos |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CN108530458A (zh) | 2013-11-01 | 2018-09-14 | 卡拉制药公司 | 治疗化合物的结晶形式及其用途 |
| WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| US9463201B2 (en) * | 2014-10-19 | 2016-10-11 | M.G. Therapeutics Ltd | Compositions and methods for the treatment of meibomian gland dysfunction |
| HK1248570A1 (zh) * | 2015-05-29 | 2018-10-19 | 西德奈克西斯公司 | D2o稳定化的药物制剂 |
| EP3416654B1 (en) | 2016-02-18 | 2021-10-27 | Invirsa, Inc. | Medical use of 5'-adenosine diphosphate ribose (adpr) |
| US11040062B2 (en) | 2016-04-14 | 2021-06-22 | Azura Ophthalmics Ltd. | Selenium disulfide compositions for use in treating meibomian gland dysfunction |
| SG11201809811VA (en) * | 2016-05-05 | 2018-12-28 | Veloce Biopharma Llc | Compositions and methods for treatment of inflammation or infection of the eye |
| EP3509421A4 (en) | 2016-09-08 | 2020-05-20 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| US10253036B2 (en) | 2016-09-08 | 2019-04-09 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3509423A4 (en) | 2016-09-08 | 2020-05-13 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| KR101935250B1 (ko) * | 2017-07-04 | 2019-01-04 | 김대황 | 요오드제 및 삼투성 미각제를 포함하는 눈, 구강용, 비강용 또는 흡입용 항바이러스 및 항균 조성물 |
| EP4226971A1 (en) | 2018-03-27 | 2023-08-16 | Invirsa, Inc. | Methods for the use of 5'-adenosine diphosphate ribose (adpr) |
| CN115279458A (zh) | 2020-01-10 | 2022-11-01 | 阿祖拉眼科有限公司 | 组合物和敏感性说明 |
| CN113797162B (zh) * | 2020-06-17 | 2023-05-05 | 成都瑞沐生物医药科技有限公司 | 一种滴眼给药治疗黄斑水肿、视神经炎和非感染性眼内炎的眼用制剂 |
| CN112305115B (zh) * | 2020-10-29 | 2022-08-23 | 诺峰药业(成都)有限公司 | 一种检测二氟泼尼酯眼用乳剂中的降解杂质及其含量的高效液相色谱方法 |
| KR20220062790A (ko) | 2020-11-09 | 2022-05-17 | 정춘영 | 포비돈 아이오딘계 소독액 |
| US20240082188A1 (en) * | 2021-01-21 | 2024-03-14 | Taejoon Pharmaceutical Co., Ltd. | Ophthalmic composition |
| EP4282432A4 (en) * | 2021-01-22 | 2025-01-29 | Chengdu Ruimu Biopharmaceuticals Co., Ltd. | CARRIER OR AUXILIARY SUBSTANCE FOR OPHTHALMIC PREPARATION, ITS PREPARATION METHOD AND ITS APPLICATION |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3886268A (en) * | 1972-05-30 | 1975-05-27 | Synergistics | Iodophor-steroid compound pharmaceutical compositions |
| US7767217B2 (en) * | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| DK2291081T3 (da) * | 2008-06-12 | 2020-08-10 | Foresight Biotherapeutics Inc | Povidon-iod, et nyt alternativt konserveringsmiddel til ophthalmiske sammensætninger |
| JP2013514373A (ja) * | 2009-12-15 | 2013-04-25 | フォーサイト・バイオセラピューティクス・インコーポレーテッド | 非刺激性の眼科用ポビドンヨード組成物 |
| TW201808311A (zh) * | 2011-09-16 | 2018-03-16 | 遠景生物製藥股份有限公司 | 安定之普維酮-碘組成物 |
-
2012
- 2012-05-11 CA CA2835343A patent/CA2835343A1/en not_active Abandoned
- 2012-05-11 EP EP12781920.9A patent/EP2707006B1/en active Active
- 2012-05-11 BR BR112013028735A patent/BR112013028735A2/pt not_active Application Discontinuation
- 2012-05-11 AU AU2012253335A patent/AU2012253335B2/en not_active Ceased
- 2012-05-11 US US14/117,086 patent/US20150038473A1/en not_active Abandoned
- 2012-05-11 MX MX2013012971A patent/MX360666B/es active IP Right Grant
- 2012-05-11 TW TW106131033A patent/TWI717552B/zh not_active IP Right Cessation
- 2012-05-11 WO PCT/US2012/037563 patent/WO2012155062A1/en not_active Ceased
- 2012-05-11 JP JP2014510502A patent/JP6072009B2/ja not_active Expired - Fee Related
- 2012-05-11 TW TW101116855A patent/TWI632914B/zh not_active IP Right Cessation
- 2012-05-11 PE PE2013002407A patent/PE20141070A1/es not_active Application Discontinuation
- 2012-05-11 KR KR1020137032559A patent/KR101967938B1/ko not_active Expired - Fee Related
- 2012-05-11 CN CN201280034191.2A patent/CN103957922A/zh active Pending
- 2012-05-14 AR ARP120101708A patent/AR086399A1/es not_active Application Discontinuation
-
2013
- 2013-10-17 CL CL2013003016A patent/CL2013003016A1/es unknown
- 2013-12-09 CO CO13287528A patent/CO6821949A2/es not_active Application Discontinuation
- 2013-12-09 EC ECSP13013069 patent/ECSP13013069A/es unknown
-
2016
- 2016-09-02 AU AU2016222491A patent/AU2016222491A1/en not_active Abandoned
- 2016-12-22 JP JP2016248924A patent/JP6359619B2/ja not_active Expired - Fee Related
-
2018
- 2018-05-17 AU AU2018203492A patent/AU2018203492A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP6359619B2 (ja) | 2018-07-18 |
| AR086399A1 (es) | 2013-12-11 |
| KR20140045375A (ko) | 2014-04-16 |
| US20150038473A1 (en) | 2015-02-05 |
| TW201811340A (zh) | 2018-04-01 |
| CL2013003016A1 (es) | 2014-05-02 |
| EP2707006A4 (en) | 2014-09-24 |
| TWI632914B (zh) | 2018-08-21 |
| AU2012253335A1 (en) | 2013-05-02 |
| ECSP13013069A (es) | 2015-03-31 |
| JP2014516954A (ja) | 2014-07-17 |
| KR101967938B1 (ko) | 2019-04-10 |
| MX2013012971A (es) | 2013-12-12 |
| EP2707006B1 (en) | 2019-07-03 |
| PE20141070A1 (es) | 2014-09-14 |
| AU2018203492A1 (en) | 2018-06-07 |
| CO6821949A2 (es) | 2013-12-31 |
| AU2016222491A1 (en) | 2016-09-22 |
| JP6072009B2 (ja) | 2017-02-01 |
| TWI717552B (zh) | 2021-02-01 |
| WO2012155062A1 (en) | 2012-11-15 |
| AU2012253335B2 (en) | 2016-08-04 |
| TW201311256A (zh) | 2013-03-16 |
| EP2707006A1 (en) | 2014-03-19 |
| JP2017095474A (ja) | 2017-06-01 |
| CA2835343A1 (en) | 2012-11-15 |
| CN103957922A (zh) | 2014-07-30 |
| MX360666B (es) | 2018-11-13 |
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Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) |
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Owner name: FORESIGHT BIOTHERAPEUTICS, INC. (US) Free format text: ANULADA A PUBLICACAO CODIGO 25.1 NA RPI NO 2648 DE 05/10/2021 POR TER SIDO INDEVIDA. |
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