BR112013025878A2 - composição farmacêutica e método para produzir uma composição farmacêutica - Google Patents

composição farmacêutica e método para produzir uma composição farmacêutica

Info

Publication number
BR112013025878A2
BR112013025878A2 BR112013025878A BR112013025878A BR112013025878A2 BR 112013025878 A2 BR112013025878 A2 BR 112013025878A2 BR 112013025878 A BR112013025878 A BR 112013025878A BR 112013025878 A BR112013025878 A BR 112013025878A BR 112013025878 A2 BR112013025878 A2 BR 112013025878A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
producing
phytosterol
composition
lycopene
Prior art date
Application number
BR112013025878A
Other languages
English (en)
Inventor
Morris Zelkha
Yoav Levy
Yoav Sharoni
Yossi Levy
Original Assignee
Lycored Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lycored Ltd filed Critical Lycored Ltd
Publication of BR112013025878A2 publication Critical patent/BR112013025878A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

resumo “composição farmacêutica e método para produzir uma composição farmacêutica” é divulgada uma composição farmacêutica para administração oral compreendendo uma quantidade terapeuticamente eficaz de uma combinação de um caroteno e pelo menos um fitosterol, sendo que a razão do dito licopeno para o dito fitosterol na dita composição farmacêutica é de no máximo cerca de 5:1, e sendo que a dita composição produz uma inibição sinérgica do crescimento celular e efeitos anti-inflamatórios. 1
BR112013025878A 2011-04-07 2012-04-05 composição farmacêutica e método para produzir uma composição farmacêutica BR112013025878A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/081,643 US8460718B2 (en) 2011-04-07 2011-04-07 Synergistic compositions and methods
PCT/IL2012/050128 WO2012137209A1 (en) 2011-04-07 2012-04-05 Synergistic compositions and methods

Publications (1)

Publication Number Publication Date
BR112013025878A2 true BR112013025878A2 (pt) 2016-12-20

Family

ID=46146999

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013025878A BR112013025878A2 (pt) 2011-04-07 2012-04-05 composição farmacêutica e método para produzir uma composição farmacêutica

Country Status (11)

Country Link
US (1) US8460718B2 (pt)
EP (1) EP2694044B1 (pt)
JP (2) JP6153922B2 (pt)
CN (1) CN103619329B (pt)
AU (1) AU2012240955B2 (pt)
BR (1) BR112013025878A2 (pt)
CA (1) CA2832273C (pt)
ES (1) ES2939316T3 (pt)
RU (1) RU2657594C2 (pt)
WO (1) WO2012137209A1 (pt)
ZA (1) ZA201307187B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL141038A (en) * 2001-01-23 2006-10-05 Lycored Natural Prod Ind Ltd Use of carotenoids for the preparation of substances for the treatment of high blood pressure
EP2081652B1 (de) 2006-10-27 2016-12-14 Edelrid GmbH & Co. KG Sicherungseinrichtung
KR20150109471A (ko) * 2013-01-22 2015-10-01 라이코드 리미티드 열처리된 순수 토마토 농축물을 포함하는 조성물
CN107106625A (zh) * 2014-11-25 2017-08-29 利库德有限公司 具有减少量的番茄红素的生物学活性番茄组合物
JP2016119898A (ja) * 2014-12-16 2016-07-07 ライコード・リミテツド 着色剤特性が改善されたリコピン組成物
US9669006B2 (en) 2015-07-28 2017-06-06 U.S. Nutraceuticals, LLC Composition and method to treat and alleviate symptoms of hot flashes in a female subject
CN108771661A (zh) * 2018-05-29 2018-11-09 上海天龙生物科技有限公司 一种植物甾醇番茄红素软胶囊
JPWO2020017489A1 (ja) * 2018-07-17 2021-08-02 再生ファーマ株式会社 炎症性サイトカイン産生抑制剤
JP6497827B1 (ja) * 2018-07-17 2019-04-10 株式会社 バイオミメティクスシンパシーズ エイコサノイド産生促進剤
CN115697312A (zh) * 2020-05-07 2023-02-03 乐康瑞德有限公司 富含前番茄红素的组合物及使用其的方法
CN112057494B (zh) * 2020-09-04 2022-04-08 湖南中医药大学 獐牙菜的提取物在制备抑制谷胱甘肽s-转移酶活性的药物中的应用
CN112603982A (zh) * 2020-12-28 2021-04-06 完美（中国）有限公司 一种抑制前列腺增生的组合物
CN112807403A (zh) * 2020-12-28 2021-05-18 完美（中国）有限公司 一种组合物在制备抑制前列腺癌的制品中的应用
CN116327814A (zh) * 2022-09-08 2023-06-27 健合香港有限公司 一种降血脂、降胆固醇的组合物及其制备方法和用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837311A (en) 1993-12-13 1998-11-17 Makhteshim Chemical Works Ltd. Industrial processing of tomatoes and product thereof
IL129442A0 (en) * 1999-04-14 2000-02-29 Lycored Natural Prod Ind Ltd Compounds useful in reducing the level of insulin like growth factor-1 (IGF-1) in blood
US20050031557A1 (en) 1999-09-08 2005-02-10 Christine Gaertner Oral administration of beta-carotene, lycopene and lutein for human skin protection
WO2001026668A1 (en) 1999-10-14 2001-04-19 Unilever N.V. Compositions with anti-prostate cancer activity
JP4658290B2 (ja) * 2000-06-26 2011-03-23 丸善製薬株式会社 線維芽細胞増殖作用剤、美容用飲食品および皮膚化粧料
IL151342A (en) 2002-08-19 2005-06-19 Lycored Natural Prod Ind Ltd Industrial process for working up tomatoes and products obtained therefrom
US20070082044A1 (en) * 2004-03-10 2007-04-12 Trustees Of Tufts College Synergistic effect of compositions comprising carotenoids selected from lutein, beta-carotene and lycopene
PL1732605T3 (pl) 2004-03-29 2019-09-30 Wyeth Llc Multiwitaminowe i mineralne suplementy odżywcze
US20060093592A1 (en) 2004-10-04 2006-05-04 Nutracea Synbiotics
WO2006046222A2 (en) 2004-10-26 2006-05-04 Lycored Natural Products Industries Ltd. A method for fortifying food stuff with phytonutrients and food products obtained thereby
US20060116334A1 (en) 2004-12-01 2006-06-01 Curt Hendrix Folate based composition for treatment of the cardiovascular system
ES2285923B1 (es) 2005-12-14 2008-10-16 Dieta Mediterranea Aceites Y Vinagres, S.A. Producto para su utilizacion en la prevencion y tratamiento de enfermedades cardiovasculares, cancer y enfermedades inflamatorias cronicas.
JP5089887B2 (ja) 2006-01-23 2012-12-05 日本精化株式会社 生理活性物質含有複合体
TW200738227A (en) 2006-04-03 2007-10-16 Panatoz Corp One kind of multi-carotenoids and its administration
US20080260771A1 (en) 2006-09-12 2008-10-23 Olalde Rangel Jose A Prostate disorder(s) phyto-nutraceutical synergistic composition
US7794758B2 (en) * 2007-04-05 2010-09-14 Pmc Formulas, Inc. Compounds and methods for promoting cellular health and treatment of cancer
US8394425B2 (en) 2007-04-05 2013-03-12 Pmc Formulas, Inc. Methods for promoting cellular health and treatment of cancer
IL184575A0 (en) * 2007-07-12 2008-01-20 Lycored Ltd Synergistic combinations for treating hypertension
CA2836248A1 (en) 2010-10-14 2012-04-19 Cape Peninsula University Of Technology Food supplement including a spectrum of carotenoids, tocopherol, tocotrienol, and omega-3 fatty acids

Also Published As

Publication number Publication date
JP6153922B2 (ja) 2017-06-28
CN103619329B (zh) 2016-07-06
CA2832273A1 (en) 2012-10-11
RU2657594C2 (ru) 2018-06-14
RU2013144735A (ru) 2015-05-20
ES2939316T3 (es) 2023-04-20
US20120258182A1 (en) 2012-10-11
JP2016196461A (ja) 2016-11-24
US8460718B2 (en) 2013-06-11
EP2694044A1 (en) 2014-02-12
ZA201307187B (en) 2014-12-23
CN103619329A (zh) 2014-03-05
CA2832273C (en) 2019-11-12
WO2012137209A1 (en) 2012-10-11
AU2012240955B2 (en) 2017-05-11
AU2012240955A1 (en) 2013-10-17
EP2694044B1 (en) 2022-12-21
JP2014513075A (ja) 2014-05-29

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]