BR112013016153A2 - composições imunogênicas estáveis de antígenos de staphylococcus aureus - Google Patents
composições imunogênicas estáveis de antígenos de staphylococcus aureusInfo
- Publication number
- BR112013016153A2 BR112013016153A2 BR112013016153A BR112013016153A BR112013016153A2 BR 112013016153 A2 BR112013016153 A2 BR 112013016153A2 BR 112013016153 A BR112013016153 A BR 112013016153A BR 112013016153 A BR112013016153 A BR 112013016153A BR 112013016153 A2 BR112013016153 A2 BR 112013016153A2
- Authority
- BR
- Brazil
- Prior art keywords
- staphylococcus aureus
- immunogenic compositions
- aureus antigens
- stable immunogenic
- stable
- Prior art date
Links
- 241000191967 Staphylococcus aureus Species 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061426476P | 2010-12-22 | 2010-12-22 | |
| PCT/IB2011/055883 WO2012085872A2 (en) | 2010-12-22 | 2011-12-21 | Stable immunogenic compositions of staphylococcus aureus antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013016153A2 true BR112013016153A2 (pt) | 2017-07-11 |
Family
ID=45444677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013016153A BR112013016153A2 (pt) | 2010-12-22 | 2011-12-21 | composições imunogênicas estáveis de antígenos de staphylococcus aureus |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20130259896A1 (https=) |
| EP (2) | EP2654784B1 (https=) |
| JP (1) | JP6097478B2 (https=) |
| KR (2) | KR20130114210A (https=) |
| CN (1) | CN103826656B (https=) |
| AU (1) | AU2011346535B2 (https=) |
| BR (1) | BR112013016153A2 (https=) |
| CA (1) | CA2819120C (https=) |
| DK (2) | DK3150222T3 (https=) |
| ES (2) | ES2614815T3 (https=) |
| HU (2) | HUE047263T2 (https=) |
| IL (1) | IL226793B (https=) |
| MX (1) | MX350170B (https=) |
| PL (2) | PL3150222T3 (https=) |
| PT (2) | PT2654784T (https=) |
| RU (1) | RU2570730C2 (https=) |
| SI (2) | SI2654784T1 (https=) |
| WO (1) | WO2012085872A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ553776A (en) | 2004-09-22 | 2010-05-28 | Glaxosmithkline Biolog Sa | Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide. |
| SA110310528B1 (ar) | 2009-06-22 | 2014-07-02 | Wyeth Llc | التركيبات المولدة للمناعة لأنتيجينات ستافيلوكوكس أوريس |
| SG10201406432RA (en) | 2009-06-22 | 2014-11-27 | Wyeth Llc | Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions |
| PL2575870T3 (pl) * | 2010-06-04 | 2017-05-31 | Wyeth Llc | Preparaty szczepionek |
| AU2012266880A1 (en) * | 2011-03-16 | 2013-10-03 | Regents Of The University Of Minnesota | Compositions and methods for inducing immune responses against bacteria in the genus staphylococcus |
| GB201310008D0 (en) * | 2013-06-05 | 2013-07-17 | Glaxosmithkline Biolog Sa | Immunogenic composition for use in therapy |
| US10195262B2 (en) * | 2013-12-04 | 2019-02-05 | Glaxosmithkline Biologicals S.A. | Prevention of Staphylococcus aureus infections by glycoprotein vaccines synthesized in Escherichia coli |
| IL310015B2 (en) * | 2013-12-31 | 2026-02-01 | Access To Advanced Health Inst | Single vial formulation |
| PL3129001T3 (pl) * | 2014-04-10 | 2020-06-29 | Asit Biotech S.A. | Preparat alergenów wolny od hsp |
| CN110996992A (zh) * | 2017-08-16 | 2020-04-10 | 默沙东公司 | 肺炎球菌缀合物疫苗制剂 |
| GB201802339D0 (en) | 2018-02-13 | 2018-03-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| KR102646145B1 (ko) | 2018-05-31 | 2024-03-11 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 모공 축소용 조성물 |
| KR102058961B1 (ko) * | 2018-07-28 | 2019-12-24 | 주식회사 엑소코바이오 | 엑소좀의 동결건조 방법 |
| KR102163806B1 (ko) | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| BR112022013730A2 (pt) * | 2020-01-13 | 2022-10-11 | Aptevo Res & Development Llc | Métodos e composições para prevenir a adsorção de proteínas terapêuticas aos componentes do sistema de distribuição de drogas |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902506A (en) | 1983-07-05 | 1990-02-20 | The University Of Rochester | Immunogenic conjugates |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| SE8405493D0 (sv) | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
| US5078996A (en) | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| CA2017507C (en) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
| IT1253009B (it) | 1991-12-31 | 1995-07-10 | Sclavo Ricerca S R L | Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini |
| US5571515A (en) | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6008341A (en) | 1994-08-22 | 1999-12-28 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| BE1008978A5 (fr) | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| WO1997014800A1 (en) | 1995-10-16 | 1997-04-24 | Smithkline Beecham Plc | Novel saliva binding protein |
| GB9622159D0 (en) | 1996-10-24 | 1996-12-18 | Solvay Sociutu Anonyme | Polyanionic polymers as adjuvants for mucosal immunization |
| GB9622660D0 (en) | 1996-10-31 | 1997-01-08 | Biocine Spa | Immunogenic detoxified mutant toxin |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| EP1034277B1 (en) | 1997-11-26 | 2012-06-27 | Inhibitex, Inc. | Extracellular matrix-binding proteins from Staphylococcus aureus |
| US6680195B1 (en) | 1997-11-26 | 2004-01-20 | Inhibitex, Inc. | Extracellular matrix-binding proteins from staphylococcus aureus |
| ES2322409T3 (es) * | 1998-08-31 | 2009-06-19 | Inhibitex, Inc. | Vacunas multicomponentes contra staphylococcus aureus. |
| US6936258B1 (en) | 1999-03-19 | 2005-08-30 | Nabi Biopharmaceuticals | Staphylococcus antigen and vaccine |
| US7115730B1 (en) | 1999-04-27 | 2006-10-03 | Chiron Srl | Immunogenic detoxified mutant E. coli LT-A-toxin |
| US7384640B1 (en) | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
| RU2413520C2 (ru) | 2000-06-08 | 2011-03-10 | Интерселл Аг | Вакцинная композиция, содержащая иммуностимулирующие олигодезоксинуклеотиды |
| AT410635B (de) | 2000-10-18 | 2003-06-25 | Cistem Biotechnologies Gmbh | Vakzin-zusammensetzung |
| US7332174B2 (en) | 2001-06-07 | 2008-02-19 | Wyeth Holdings Corporation | Mutant forms of cholera holotoxin as an adjuvant |
| AU2002346249B2 (en) | 2001-06-07 | 2007-03-15 | The Regents Of The University Of Colorado | Mutant Forms of Cholera Holotoxin as an Adjuvant |
| MXPA03011701A (es) | 2001-06-15 | 2004-12-06 | Nhibitex Inc | Anticuerpos monoclonales y policlonales de reaccion que reconocen las proteinas de superficie a partir de estafilococos coagulasa-negativos y staphylococcus aureus. |
| GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| CA2517439C (en) | 2003-03-07 | 2013-07-23 | Wyeth Holdings Corporation | Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| US20060251675A1 (en) | 2003-03-17 | 2006-11-09 | Michael Hagen | Mutant cholera holotoxin as an adjuvant and an antigen carrier protein |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| NZ553776A (en) * | 2004-09-22 | 2010-05-28 | Glaxosmithkline Biolog Sa | Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide. |
| GB0606416D0 (en) * | 2006-03-30 | 2006-05-10 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2476433A1 (en) * | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| AR060187A1 (es) | 2006-03-30 | 2008-05-28 | Glaxosmithkline Biolog Sa | Composicion inmunogenica |
| WO2007127668A2 (en) | 2006-04-26 | 2007-11-08 | Wyeth | Novel processes for coating container means which inhibit precipitation of polysaccharide-protein conjugate formulations |
| MX2009004862A (es) * | 2006-11-07 | 2009-07-17 | Sanofi Pasteur Biologics Co | Estabilizacion de vacunas por liofilizacion. |
| CN101959527B (zh) | 2008-03-05 | 2016-04-20 | 赛诺菲巴斯德有限公司 | 一种使含佐剂的疫苗组合物稳定的方法 |
| SA110310528B1 (ar) * | 2009-06-22 | 2014-07-02 | Wyeth Llc | التركيبات المولدة للمناعة لأنتيجينات ستافيلوكوكس أوريس |
-
2011
- 2011-12-21 EP EP11804822.2A patent/EP2654784B1/en active Active
- 2011-12-21 US US13/993,887 patent/US20130259896A1/en not_active Abandoned
- 2011-12-21 CA CA2819120A patent/CA2819120C/en active Active
- 2011-12-21 PT PT118048222T patent/PT2654784T/pt unknown
- 2011-12-21 DK DK16193095.3T patent/DK3150222T3/da active
- 2011-12-21 PL PL16193095T patent/PL3150222T3/pl unknown
- 2011-12-21 RU RU2013128277/15A patent/RU2570730C2/ru active IP Right Revival
- 2011-12-21 HU HUE16193095A patent/HUE047263T2/hu unknown
- 2011-12-21 AU AU2011346535A patent/AU2011346535B2/en not_active Ceased
- 2011-12-21 WO PCT/IB2011/055883 patent/WO2012085872A2/en not_active Ceased
- 2011-12-21 DK DK11804822.2T patent/DK2654784T3/en active
- 2011-12-21 HU HUE11804822A patent/HUE033072T2/hu unknown
- 2011-12-21 CN CN201180068105.5A patent/CN103826656B/zh not_active Expired - Fee Related
- 2011-12-21 MX MX2013006960A patent/MX350170B/es active IP Right Grant
- 2011-12-21 EP EP16193095.3A patent/EP3150222B1/en active Active
- 2011-12-21 BR BR112013016153A patent/BR112013016153A2/pt not_active Application Discontinuation
- 2011-12-21 SI SI201131064A patent/SI2654784T1/sl unknown
- 2011-12-21 ES ES11804822.2T patent/ES2614815T3/es active Active
- 2011-12-21 SI SI201131825T patent/SI3150222T1/sl unknown
- 2011-12-21 PL PL11804822T patent/PL2654784T3/pl unknown
- 2011-12-21 KR KR1020137018851A patent/KR20130114210A/ko not_active Ceased
- 2011-12-21 KR KR1020157031951A patent/KR101808398B1/ko not_active Expired - Fee Related
- 2011-12-21 PT PT161930953T patent/PT3150222T/pt unknown
- 2011-12-21 ES ES16193095T patent/ES2769425T3/es active Active
- 2011-12-22 JP JP2011280781A patent/JP6097478B2/ja not_active Expired - Fee Related
-
2013
- 2013-06-06 IL IL226793A patent/IL226793B/en active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |