BR112013009004A8 - Uso de composição farmacêutica ou kit de partes compreendendo combinações de agonistas dereceptor de serotonina - Google Patents
Uso de composição farmacêutica ou kit de partes compreendendo combinações de agonistas dereceptor de serotoninaInfo
- Publication number
- BR112013009004A8 BR112013009004A8 BR112013009004A BR112013009004A BR112013009004A8 BR 112013009004 A8 BR112013009004 A8 BR 112013009004A8 BR 112013009004 A BR112013009004 A BR 112013009004A BR 112013009004 A BR112013009004 A BR 112013009004A BR 112013009004 A8 BR112013009004 A8 BR 112013009004A8
- Authority
- BR
- Brazil
- Prior art keywords
- kit
- parts
- serotonin receptor
- pharmaceutical composition
- receptor agonist
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000000952 serotonin receptor agonist Substances 0.000 title abstract 2
- 208000016285 Movement disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000003521 serotonin 5-HT1 receptor agonist Substances 0.000 abstract 2
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 206010043118 Tardive Dyskinesia Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000009251 neurologic dysfunction Effects 0.000 abstract 1
- 208000015015 neurological dysfunction Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
COMBINAÇÕES DE AGONISTAS DE RECEPTOR DE SEROTONINA PARA O TRATAMENTO DE DISTÚRBIOS DE MOVIMENTO. A presente invenção refere-se ao uso de agonistas de 5-HT1 em composições farmacêuticas, compostos e métodos para o tratamento de distúrbios de movimento relacionados com disfunções neurológicas. A invenção é particularmente relevante para o tratamento de pacientes sofrendo de discinesia tardia, doença de Parkinson e distúrbios associados do mesmo. Kit de partes compreendendo os compostos ou composições farmacêuticas de agonista de 5-HT1 de acordo com a presente invenção, bem como métodos de preparação são também fornecidos pela presente invenção.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39354510P | 2010-10-15 | 2010-10-15 | |
US61/393,545 | 2010-10-15 | ||
DKPA201070441 | 2010-10-15 | ||
DKPA201070441 | 2010-10-15 | ||
US201161491945P | 2011-06-01 | 2011-06-01 | |
US61/491,945 | 2011-06-01 | ||
PCT/DK2011/050383 WO2012048710A1 (en) | 2010-10-15 | 2011-10-13 | Combinations of serotonin receptor agonists for treatment of movement disorders |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112013009004A2 BR112013009004A2 (pt) | 2016-07-05 |
BR112013009004A8 true BR112013009004A8 (pt) | 2017-12-26 |
BR112013009004B1 BR112013009004B1 (pt) | 2022-05-10 |
Family
ID=44883032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013009004-9A BR112013009004B1 (pt) | 2010-10-15 | 2011-10-13 | Uso de composição farmacêutica ou kit de partes compreendendo combinações de agonistas dereceptor de serotonina |
Country Status (22)
Country | Link |
---|---|
US (2) | US9186359B2 (pt) |
EP (1) | EP2627328B1 (pt) |
JP (1) | JP5907975B2 (pt) |
KR (1) | KR101825972B1 (pt) |
CN (2) | CN105193809B (pt) |
AU (1) | AU2011316225B2 (pt) |
BR (1) | BR112013009004B1 (pt) |
CA (1) | CA2813648C (pt) |
CY (1) | CY1118314T1 (pt) |
DK (1) | DK2627328T3 (pt) |
ES (1) | ES2602973T3 (pt) |
HR (1) | HRP20161402T1 (pt) |
HU (1) | HUE031661T2 (pt) |
IL (1) | IL225758A (pt) |
LT (1) | LT2627328T (pt) |
MX (1) | MX353625B (pt) |
PL (1) | PL2627328T3 (pt) |
PT (1) | PT2627328T (pt) |
RS (1) | RS55332B1 (pt) |
RU (1) | RU2611376C2 (pt) |
SI (1) | SI2627328T1 (pt) |
WO (1) | WO2012048710A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012163365A1 (en) * | 2011-06-01 | 2012-12-06 | Concit Pharma Aps | Combinations of serotonin receptor agonists for treatment of movement disorders |
BR112014025907B1 (pt) * | 2012-04-18 | 2023-02-14 | Contera Pharma Aps | Formulação farmacêutica disponível para administração por via oral adequada para manejo aprimorado de transtornos do movimento |
AU2013274667B2 (en) * | 2012-06-11 | 2018-03-08 | Psychogenics, Inc. | Treatment of motor and movement disorder side effects associated with Parkinson's disease treatments |
KR20170021848A (ko) * | 2014-06-26 | 2017-02-28 | 콘테라 파르마 에이피에스 | 부스피론 대사물의 용도 |
US10548885B2 (en) | 2014-07-09 | 2020-02-04 | Pierre Fabre Medicament | Method for treating movement disorders with befiradol |
WO2016210431A1 (en) * | 2015-06-26 | 2016-12-29 | Wright State University | Method of treating sepsis-induced myopathy |
US11013830B2 (en) * | 2015-11-20 | 2021-05-25 | Institut Pasteur | 5-hydroxytryptamine 1B receptor-stimulating agent for enhancing in vivo engraftment potential |
WO2018011181A1 (en) | 2016-07-11 | 2018-01-18 | Contera Pharma Aps | Pulsatile drug delivery system for treating morning akinesia |
WO2020127954A1 (en) | 2018-12-20 | 2020-06-25 | Contera Pharma Aps | Treatment of movement disorders |
AU2020407614A1 (en) * | 2019-12-20 | 2022-08-18 | The Jackson Laboratory | Molecular targets for addiction |
CN112931397B (zh) * | 2021-01-25 | 2024-02-27 | 江南大学 | 一种帕金森病动物模型的构建方法 |
CN114712365B (zh) * | 2022-06-07 | 2022-08-23 | 山东绿叶制药有限公司 | Trk抑制剂在制备治疗迟发性运动障碍药物中的应用 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE759371A (fr) | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
US3976776A (en) | 1972-12-06 | 1976-08-24 | Mead Johnson & Company | Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones |
US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
US4182763A (en) | 1978-05-22 | 1980-01-08 | Mead Johnson & Company | Buspirone anti-anxiety method |
US4356108A (en) | 1979-12-20 | 1982-10-26 | The Mead Corporation | Encapsulation process |
US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
US4438119A (en) * | 1982-12-23 | 1984-03-20 | Mead Johnson & Company | Method for alleviation of extrapyramidal motor disorders |
US4640921A (en) | 1986-02-04 | 1987-02-03 | Bristol-Myers | Treatment of sexual dysfunction with buspirone |
US4687772A (en) | 1986-10-07 | 1987-08-18 | Bristol-Myers Company | Method for improvement of short term memory |
US4777173A (en) | 1987-03-25 | 1988-10-11 | Bristol-Myers Company | Method for treatment of alcohol abuse |
US5185329A (en) | 1988-08-30 | 1993-02-09 | Bristol-Myers Squibb Company | Method for treatment of substance addiction |
US6432956B1 (en) | 1990-02-12 | 2002-08-13 | William C. Dement | Method for treatment of sleep apneas |
CA2064815C (en) | 1990-06-07 | 1999-11-16 | Alan Duncan Robertson | Therapeutic heterocyclic compounds |
US5633009A (en) | 1990-11-28 | 1997-05-27 | Sano Corporation | Transdermal administration of azapirones |
US5431922A (en) | 1991-03-05 | 1995-07-11 | Bristol-Myers Squibb Company | Method for administration of buspirone |
GB9209882D0 (en) | 1992-05-07 | 1992-06-24 | Glaxo Lab Sa | Compositions |
US5484788A (en) | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
US5637314A (en) | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
GB9706089D0 (en) * | 1997-03-24 | 1997-05-14 | Scherer Ltd R P | Pharmaceutical composition |
US6150365A (en) | 1999-08-05 | 2000-11-21 | Bristol-Myers Squibb Company | Anxiety method |
GB9928578D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Pharmaceutical formulations |
EP1341777B1 (en) * | 2000-11-29 | 2007-09-26 | Eli Lilly And Company | 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatement of incontinence |
WO2002053139A2 (en) * | 2001-01-05 | 2002-07-11 | Eli Lilly And Company | Excitatory amino acid receptor antagonist and 5-ht1f agonist combination: a method for the treatment of neurological disorders |
US8329734B2 (en) | 2009-07-27 | 2012-12-11 | Afgin Pharma Llc | Topical therapy for migraine |
EP1425008B1 (en) * | 2001-09-12 | 2006-10-04 | MERCK PATENT GmbH | Use of substituted aminomethyl chromans in the treatment of side effects of neuroleptics |
DE10353657A1 (de) * | 2003-11-17 | 2005-06-23 | Merck Patent Gmbh | Indolderivate |
WO2005075467A2 (en) | 2004-02-06 | 2005-08-18 | Ciba Specialty Chemicals Holding Inc. | Crystalline forms of zolmitriptan |
JP2008512436A (ja) * | 2004-09-07 | 2008-04-24 | ファイザー・インク | 片頭痛治療用の5−HT(1)受容体アゴニストとα2δリガンドの組み合わせ |
US9066903B2 (en) | 2006-02-28 | 2015-06-30 | The United States Of America As Represented By The Department Of Veterans Affairs | Pharmacological treatment of Parkinson's disease |
WO2007144422A2 (en) * | 2006-06-16 | 2007-12-21 | Solvay Pharmaceuticals B.V. | Combination preparations comprising bifeprunox and l-dopa |
TW200831479A (en) * | 2006-09-26 | 2008-08-01 | Cytrx Corp | Pharmaceutical compositions and methods for treating diseases |
WO2008047839A1 (fr) * | 2006-10-19 | 2008-04-24 | Dainippon Sumitomo Pharma Co., Ltd. | Agoniste du récepteur de la 5-ht1a |
WO2008115797A1 (en) * | 2007-03-16 | 2008-09-25 | Pavo, Inc. | Therapeutic compositions and methods |
WO2009002084A2 (en) | 2007-06-27 | 2008-12-31 | Hanmi Pharm. Co., Ltd. | Method for preparing rapidly disintegrating formulation for oral administration and apparatus for preparing and packing the same |
EP2317996A1 (en) | 2008-06-24 | 2011-05-11 | Anders Björklund | Eltoprazine for suppression of l-dopa induced dyskinesias |
CN102186461A (zh) | 2008-10-14 | 2011-09-14 | 麦克内尔股份公司 | 多部分口腔内剂型及其用途 |
AU2010206221B2 (en) | 2009-01-23 | 2016-07-14 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Controlled release pharmaceutical or food formulation and process for its preparation |
SG181896A1 (en) | 2009-12-23 | 2012-07-30 | Map Pharmaceuticals Inc | Novel ergoline analogs |
WO2012163365A1 (en) | 2011-06-01 | 2012-12-06 | Concit Pharma Aps | Combinations of serotonin receptor agonists for treatment of movement disorders |
-
2011
- 2011-10-13 BR BR112013009004-9A patent/BR112013009004B1/pt active IP Right Grant
- 2011-10-13 JP JP2013533090A patent/JP5907975B2/ja active Active
- 2011-10-13 PL PL11776071T patent/PL2627328T3/pl unknown
- 2011-10-13 RS RS20160985A patent/RS55332B1/sr unknown
- 2011-10-13 PT PT117760710T patent/PT2627328T/pt unknown
- 2011-10-13 WO PCT/DK2011/050383 patent/WO2012048710A1/en active Application Filing
- 2011-10-13 HU HUE11776071A patent/HUE031661T2/en unknown
- 2011-10-13 CN CN201510595196.8A patent/CN105193809B/zh active Active
- 2011-10-13 SI SI201131000A patent/SI2627328T1/sl unknown
- 2011-10-13 LT LTEP11776071.0T patent/LT2627328T/lt unknown
- 2011-10-13 MX MX2013004067A patent/MX353625B/es active IP Right Grant
- 2011-10-13 EP EP11776071.0A patent/EP2627328B1/en active Active
- 2011-10-13 KR KR1020137012486A patent/KR101825972B1/ko active IP Right Grant
- 2011-10-13 CN CN201180060726.9A patent/CN103402514B/zh active Active
- 2011-10-13 ES ES11776071.0T patent/ES2602973T3/es active Active
- 2011-10-13 CA CA2813648A patent/CA2813648C/en active Active
- 2011-10-13 AU AU2011316225A patent/AU2011316225B2/en active Active
- 2011-10-13 RU RU2013120481A patent/RU2611376C2/ru active
- 2011-10-13 US US13/879,128 patent/US9186359B2/en active Active
- 2011-10-13 DK DK11776071.0T patent/DK2627328T3/en active
-
2013
- 2013-04-14 IL IL225758A patent/IL225758A/en active IP Right Grant
-
2015
- 2015-11-10 US US14/937,286 patent/US10632116B2/en active Active
-
2016
- 2016-10-26 HR HRP20161402TT patent/HRP20161402T1/hr unknown
- 2016-11-14 CY CY20161101164T patent/CY1118314T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112013009004A8 (pt) | Uso de composição farmacêutica ou kit de partes compreendendo combinações de agonistas dereceptor de serotonina | |
EA200971107A1 (ru) | Катехоламиновые производные, полезные для лечения болезни паркинсона | |
CL2012003604A1 (es) | Compuestos heterociclicos derivados de piridina carboxamida sustituida; proceso de preparacion; composicion farmaceutica; combinacion farmaceutica; uso en el tratamiento de trastornos proliferativos celulares, enfermedad de parkinson, cancer, entre otros. | |
BR112012013431A8 (pt) | composto, composição farmacêutica e seu uso | |
EA201370154A1 (ru) | Терапия на основе лигандов хемосенсорных рецепторов | |
EA200801551A1 (ru) | Применение сульфонамидных производных в лечении расстройств метаболизма и нервной системы | |
EA201290394A1 (ru) | Морфолинотиазолы в качестве позитивных аллостерических модуляторов альфа 7 | |
EA201270767A1 (ru) | Терапия на основе лигандов хемосенсорных рецепторов | |
EA200970967A1 (ru) | Оксадиазол замещенные производные индазола для применения в качестве агонистов сфингозин 1-фосфата (sip) | |
EA201200918A1 (ru) | Производные пирролидин карбоновой кислоты как агонисты сопряженного с g-белком рецептора 43 (gpr43), фармацевтическая композиция и методы их использования при лечении метаболических нарушений | |
EA201391644A1 (ru) | Частично насыщенные трициклические соединения и способы их получения и применения | |
UY31570A1 (es) | Derivados de oxadiazol agonistas del receptor s1p1. composiciones farmacéuticas que lo comprenden y procedimientos de preparacion de los mismos | |
PT1856090E (pt) | Derivados de tiofeno substituído como antagonistas do receptor de glucagona, preparação e usos terapêuticos | |
EA201400567A1 (ru) | НОВЫЕ ПРОИЗВОДНЫЕ ЦИКЛОГЕКСИЛАМИНА, ОБЛАДАЮЩИЕ АГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К β2 АДРЕНЕРГИЧЕСКОМУ РЕЦЕПТОРУ И АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К МУСКАРИНОВОМУ РЕЦЕПТОРУ М3 | |
CY1110922T1 (el) | Ανταγωνιστες υποδοχεα γλυκαγονης, παρασκευη και θεραπευτικες χρησεις | |
EA201201541A1 (ru) | НОВЫЕ ПРОИЗВОДНЫЕ ЦИКЛОГЕКСИЛАМИНА, ОБЛАДАЮЩИЕ АГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К β2 АДРЕНЕРГИЧЕСКОМУ РЕЦЕПТОРУ И АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К M3 МУСКАРИНОВОМУ РЕЦЕПТОРУ | |
MX2011006006A (es) | Compuestos, composicion farmaceutica y metodos para utilizarse en el tratamiento de trastornos metabolicos. | |
BR112015007818A2 (pt) | composto, composição farmacêutica, e, uso de um composto e de uma composição farmacêutica | |
BR112014001908A2 (pt) | derivados aza heterocíclicos substituídos | |
EA201500651A1 (ru) | НОВЫЕ ПРОИЗВОДНЫЕ ЦИКЛОГЕКСИЛ- И ХИНУКЛИДИНИЛКАРБАМАТА, ОБЛАДАЮЩИЕ АГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К β2 АДРЕНЕРГИЧЕСКОМУ РЕЦЕПТОРУ И АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К МУСКАРИНОВОМУ РЕЦЕПТОРУ М3 | |
BR112012002265B8 (pt) | composições farmacêuticas para o tratamento de câncer e outras doenças ou distúrbios | |
BRPI1013777A8 (pt) | Compostos agonistas do receptor 5-ht4 para tratamento de distúrbios cognitivos. | |
MX2013001234A (es) | Derivados deuterados de tandospirona como agonistas del receptor 5-hidroxitriptamina 1a. | |
BR112014012459A2 (pt) | 2h-indazóis como antagonistas do receptor de ep2 | |
EA201070725A1 (ru) | Бис-пиридилпиридоны как антагонисты рецептора 1 меланинконцентрирующего гормона |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: CONTERA PHARMA APS (DK) |
|
B25G | Requested change of headquarter approved |
Owner name: CONTERA PHARMA APS (DK) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.1 NA RPI NO 2629 DE 25/05/2021 POR TER SIDO INDEVIDA. |
|
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/10/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |