BR112013007946B1 - Composições farmacêuticas e imunogênicas compreendendo polipeptídeos de hemaglutinina - Google Patents

Composições farmacêuticas e imunogênicas compreendendo polipeptídeos de hemaglutinina Download PDF

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Publication number
BR112013007946B1
BR112013007946B1 BR112013007946-0A BR112013007946A BR112013007946B1 BR 112013007946 B1 BR112013007946 B1 BR 112013007946B1 BR 112013007946 A BR112013007946 A BR 112013007946A BR 112013007946 B1 BR112013007946 B1 BR 112013007946B1
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BR
Brazil
Prior art keywords
polypeptide
glycans
binding
polypeptides
glycan
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BR112013007946-0A
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English (en)
Portuguese (pt)
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BR112013007946A2 (pt
Inventor
Kannan Tharakaraman
Karthik Viswanathan
Rahul Raman
Ram Sasisekharan
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Massachusetts Institute Of Technology
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Application filed by Massachusetts Institute Of Technology filed Critical Massachusetts Institute Of Technology
Publication of BR112013007946A2 publication Critical patent/BR112013007946A2/pt
Publication of BR112013007946B1 publication Critical patent/BR112013007946B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/108—Orthomyxoviridae (F), e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
BR112013007946-0A 2010-10-04 2011-10-04 Composições farmacêuticas e imunogênicas compreendendo polipeptídeos de hemaglutinina BR112013007946B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38963910P 2010-10-04 2010-10-04
US61/389,639 2010-10-04
PCT/US2011/054831 WO2012047941A2 (en) 2010-10-04 2011-10-04 Hemagglutinin polypeptides, and reagents and methods relating thereto

Publications (2)

Publication Number Publication Date
BR112013007946A2 BR112013007946A2 (pt) 2018-04-17
BR112013007946B1 true BR112013007946B1 (pt) 2022-07-12

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ID=44860519

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013007946-0A BR112013007946B1 (pt) 2010-10-04 2011-10-04 Composições farmacêuticas e imunogênicas compreendendo polipeptídeos de hemaglutinina

Country Status (10)

Country Link
US (2) US10226527B2 (https=)
EP (1) EP2624864B1 (https=)
JP (2) JP6029586B2 (https=)
CN (1) CN103328002B (https=)
AU (1) AU2011312178B2 (https=)
BR (1) BR112013007946B1 (https=)
CA (1) CA2813078A1 (https=)
RU (1) RU2663718C2 (https=)
SG (2) SG10201709806VA (https=)
WO (1) WO2012047941A2 (https=)

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US11230593B2 (en) 2019-03-25 2022-01-25 Visterra, Inc. Compositions and methods for treating and preventing influenza
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Also Published As

Publication number Publication date
SG10201709806VA (en) 2017-12-28
US10226527B2 (en) 2019-03-12
US20120213819A1 (en) 2012-08-23
CA2813078A1 (en) 2012-04-12
EP2624864B1 (en) 2017-12-06
US20190142931A1 (en) 2019-05-16
EP2624864A2 (en) 2013-08-14
WO2012047941A3 (en) 2013-04-11
JP2016094483A (ja) 2016-05-26
JP6029586B2 (ja) 2016-11-24
JP6143902B2 (ja) 2017-06-07
AU2011312178B2 (en) 2016-05-12
AU2011312178A1 (en) 2013-05-02
CN103328002A (zh) 2013-09-25
SG189236A1 (en) 2013-05-31
CN103328002B (zh) 2020-01-14
WO2012047941A2 (en) 2012-04-12
BR112013007946A2 (pt) 2018-04-17
RU2663718C2 (ru) 2018-08-08
RU2013114424A (ru) 2014-11-20
JP2013543499A (ja) 2013-12-05

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/10/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.