BR112013000446A2 - composição nutricional para a estimulação de síntese de proteína muscular - Google Patents
composição nutricional para a estimulação de síntese de proteína muscularInfo
- Publication number
- BR112013000446A2 BR112013000446A2 BR112013000446A BR112013000446A BR112013000446A2 BR 112013000446 A2 BR112013000446 A2 BR 112013000446A2 BR 112013000446 A BR112013000446 A BR 112013000446A BR 112013000446 A BR112013000446 A BR 112013000446A BR 112013000446 A2 BR112013000446 A2 BR 112013000446A2
- Authority
- BR
- Brazil
- Prior art keywords
- nutritional composition
- stimulation
- protein synthesis
- muscle
- muscle protein
- Prior art date
Links
- 235000016709 nutrition Nutrition 0.000 title abstract 3
- 102000008934 Muscle Proteins Human genes 0.000 title abstract 2
- 108010074084 Muscle Proteins Proteins 0.000 title abstract 2
- 238000001243 protein synthesis Methods 0.000 title abstract 2
- 230000000638 stimulation Effects 0.000 title abstract 2
- 230000014616 translation Effects 0.000 title abstract 2
- 210000003205 muscle Anatomy 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000004220 muscle function Effects 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
- 229940046008 vitamin d Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/316—Foods, ingredients or supplements having a functional effect on health having an effect on regeneration or building of ligaments or muscles
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/06—Amino acid
- A23V2250/0614—Citrulline
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/06—Amino acid
- A23V2250/0628—Leucine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/30—Other Organic compounds
- A23V2250/306—Creatine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/70—Vitamins
- A23V2250/71—Vitamin D
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Pediatric Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
composição nutricional para a estimulação de síntese de proteína muscular. a presente invenção refere-se ao uso de um estímulo derivado de aminoácido anabólico que atua em combinação com vitamina d para a fabricação de um medicamento ou composição nutricional para prevenção e/ou tratamento de uma perda de qualquer uma dentre massa muscular, força muscular, função muscular e função física ou qualquer combinação das mesmas em mamíferos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/NL2010/050436 WO2012005568A1 (en) | 2010-07-07 | 2010-07-07 | Nutritional composition for the stimulation of muscle protein synthesis |
PCT/NL2011/050488 WO2012005582A1 (en) | 2010-07-07 | 2011-07-06 | Nutritional composition for the stimulation of muscle protein synthesis |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013000446A2 true BR112013000446A2 (pt) | 2016-05-03 |
BR112013000446B1 BR112013000446B1 (pt) | 2019-10-29 |
Family
ID=43797831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013000446-0A BR112013000446B1 (pt) | 2010-07-07 | 2011-07-06 | uso de vitamina d e l-leucina em sua forma livre para a fabricação de um medicamento para a prevenção e/ou o tratamento de uma doença ou condição envolvendo perda de massa muscular em um adulto mamífero |
Country Status (10)
Country | Link |
---|---|
US (2) | US20130210780A1 (pt) |
EP (2) | EP2590521B1 (pt) |
CN (1) | CN103079415B (pt) |
BR (1) | BR112013000446B1 (pt) |
DK (1) | DK2590521T3 (pt) |
ES (1) | ES2622116T3 (pt) |
HU (1) | HUE032597T2 (pt) |
PL (1) | PL2590521T3 (pt) |
PT (1) | PT2590521T (pt) |
WO (2) | WO2012005568A1 (pt) |
Families Citing this family (39)
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WO2012005568A1 (en) | 2010-07-07 | 2012-01-12 | N.V. Nutricia | Nutritional composition for the stimulation of muscle protein synthesis |
US9605040B2 (en) | 2012-03-26 | 2017-03-28 | Axcella Health Inc. | Nutritive proteins and methods |
US9700071B2 (en) | 2012-03-26 | 2017-07-11 | Axcella Health Inc. | Nutritive fragments, proteins and methods |
RU2014143029A (ru) | 2012-03-26 | 2016-05-20 | Проньютриа, Инк. | Заряженные питательные белки и способы их применения |
CN104364259A (zh) * | 2012-03-26 | 2015-02-18 | 普罗努塔利亚公司 | 营养性片段、蛋白质和方法 |
FR2996420B1 (fr) * | 2012-10-09 | 2015-05-29 | Internat Nutrition Res Company | Produit dietetique destine a etre administre a long terme aux personnes obeses operees en chirurgie bariatrique |
US9597367B2 (en) | 2013-04-19 | 2017-03-21 | Bioventures, Llc | Methods for improving muscle and heart function |
US9961932B2 (en) | 2013-06-10 | 2018-05-08 | N.V. Nutricia | Muscle preservation in overweight or obese adult during weight loss program |
SG11201601999UA (en) | 2013-09-25 | 2016-04-28 | Pronutria Inc | Compositions and formulations for prevention and treatment of diabetes and obesity, and methods of production and use thereof in glucose and caloric control |
CA2923705C (en) | 2013-10-09 | 2024-05-14 | Nestec S.A. | Compositions comprising citrulline and leucine and their use in the treatment of diabetes and metabolic syndrome |
NL2015032B1 (en) * | 2015-06-26 | 2017-01-24 | Vitalnext B V | Compositions and methods for the treatment of malnutrition. |
CN108473384A (zh) | 2015-10-27 | 2018-08-31 | 细胞酶动物营养品公司 | 动物营养成分及相关方法 |
US10674746B2 (en) | 2015-10-27 | 2020-06-09 | Cytozyme Animal Nutrition, Inc. | Animal nutrition compositions and related methods |
US10188135B2 (en) | 2015-11-04 | 2019-01-29 | Stokley-Van Camp, Inc. | Method for inducing satiety |
US20180325956A1 (en) * | 2015-11-20 | 2018-11-15 | Nestec S.A. | Methods using whey protein to improve or maintain muscle quality |
US20190045827A1 (en) * | 2015-12-24 | 2019-02-14 | Organext Life Science B.V. | High protein nutritional product |
EP3711493A1 (en) * | 2016-11-16 | 2020-09-23 | Fresenius Kabi Deutschland GmbH | Nutritional composition for use in therapy of patients with sarcopenia and/or frailty or pre-sarcopenic and/or pre-frail patients |
CN106616980B (zh) * | 2016-12-07 | 2021-02-12 | 北京康比特体育科技股份有限公司 | 促进力量训练后肌肉合成的组合物及其制备方法 |
JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
CN109982584B (zh) | 2017-01-11 | 2023-05-02 | 雀巢产品有限公司 | 具有包含乳清蛋白质胶束的乳清蛋白质和酪蛋白源的热灭菌高蛋白质勺舀型营养组合物 |
WO2018157258A1 (en) * | 2017-03-03 | 2018-09-07 | Exerkine Corporation | Multi-nutrient composition |
CN107348522A (zh) * | 2017-08-14 | 2017-11-17 | 北京市营养源研究所 | 一种改善老年人运动系统功能的营养组合物及其制备方法 |
JP7266581B2 (ja) | 2017-08-14 | 2023-04-28 | アクセラ・ヘルス・インコーポレイテッド | 肝疾患の治療のためのアミノ酸組成物 |
CN107397230A (zh) * | 2017-08-21 | 2017-11-28 | 杭州特悘衡康生物科技有限公司 | 营养组合物、促进手术后肌肉恢复和蛋白质合成的配方食品及其应用 |
MX2020004397A (es) | 2017-11-02 | 2020-08-06 | Bioventures Llc | Uso de suplementos de aminoacidos para mejorar la sintesis de proteinas musculares. |
WO2019158541A1 (en) | 2018-02-14 | 2019-08-22 | Frieslandcampina Nederland B.V. | Nutritional compositions for musculoskeletal support for athletes |
US11026991B2 (en) * | 2018-04-18 | 2021-06-08 | Ingenious Ingredients, LP | Compositions and methods of use thereof to promote muscle growth and function |
US10596136B2 (en) | 2018-06-20 | 2020-03-24 | Axcella Health Inc. | Compositions and methods for the treatment of fat infiltration in muscle |
CN109077302A (zh) * | 2018-07-18 | 2018-12-25 | 辰欣药业股份有限公司 | 一种治疗和预防老年肌肉衰减综合症的医用食品及其制备方法 |
CN109222103B (zh) * | 2018-11-29 | 2021-04-20 | 汤臣倍健股份有限公司 | 增肌组合物和保健食品 |
CN109527585A (zh) * | 2018-12-26 | 2019-03-29 | 浙江华康药业股份有限公司 | 一种能预防和缓解肌少症的营养组合物及其制备方法 |
CH715997A1 (de) * | 2019-03-25 | 2020-09-30 | Omanda Ag | Proteingetränk und Darreichungseinheit zur Verabreichung von mit L-Leucin-angereicherten Molkenproteinkomponenten als Nahrungsanreicherung und dessen Herstellung. |
AU2020287907A1 (en) * | 2019-06-07 | 2021-11-04 | Société des Produits Nestlé S.A. | Compositions and methods using one or more autophagy-inducing amino acids to potentiate musculoskeletal effect of one or more anabolic amino acids |
CN110226756A (zh) * | 2019-06-18 | 2019-09-13 | 山东理工大学 | 预防和缓解2型糖尿病患者肌少症的蛋白组件及制备方法 |
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CN117098462A (zh) | 2021-03-17 | 2023-11-21 | N·V·努特里奇亚 | 适合肌肉功能的液体营养组合物 |
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WO2023012371A1 (en) * | 2021-08-06 | 2023-02-09 | N.V. Nutricia | Nutritional composition for muscle mass, strength and function |
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KR100549697B1 (ko) | 2004-12-10 | 2006-02-07 | 김세규 | 무산소 상태에서 순간적인 임팩트 파워를 증대 시키는 아미노산 건강기능식품 |
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ITMI20052204A1 (it) * | 2005-11-18 | 2007-05-19 | Umberto Cornelli | Uso di colostro per la profilassi delle sindroni influenzali |
KR101473017B1 (ko) * | 2006-07-05 | 2014-12-15 | 카오카부시키가이샤 | 노화 억제제 |
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JP4818177B2 (ja) * | 2007-03-27 | 2011-11-16 | ユニテックフーズ株式会社 | 高齢者向け骨・筋肉増強促進組成物 |
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WO2012005568A1 (en) | 2010-07-07 | 2012-01-12 | N.V. Nutricia | Nutritional composition for the stimulation of muscle protein synthesis |
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-
2010
- 2010-07-07 WO PCT/NL2010/050436 patent/WO2012005568A1/en active Application Filing
-
2011
- 2011-07-06 HU HUE11736184A patent/HUE032597T2/en unknown
- 2011-07-06 PL PL11736184T patent/PL2590521T3/pl unknown
- 2011-07-06 DK DK11736184.0T patent/DK2590521T3/en active
- 2011-07-06 EP EP11736184.0A patent/EP2590521B1/en not_active Revoked
- 2011-07-06 CN CN201180042986.3A patent/CN103079415B/zh active Active
- 2011-07-06 BR BR112013000446-0A patent/BR112013000446B1/pt active IP Right Grant
- 2011-07-06 PT PT117361840T patent/PT2590521T/pt unknown
- 2011-07-06 US US13/808,630 patent/US20130210780A1/en not_active Abandoned
- 2011-07-06 WO PCT/NL2011/050488 patent/WO2012005582A1/en active Application Filing
- 2011-07-06 EP EP16188290.7A patent/EP3120716A1/en active Pending
- 2011-07-06 ES ES11736184.0T patent/ES2622116T3/es active Active
-
2015
- 2015-06-25 US US14/750,061 patent/US10045999B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2012005568A1 (en) | 2012-01-12 |
HUE032597T2 (en) | 2017-10-30 |
US10045999B2 (en) | 2018-08-14 |
WO2012005582A1 (en) | 2012-01-12 |
CN103079415A (zh) | 2013-05-01 |
PL2590521T3 (pl) | 2017-08-31 |
PT2590521T (pt) | 2017-05-02 |
CN103079415B (zh) | 2016-08-10 |
EP3120716A1 (en) | 2017-01-25 |
ES2622116T3 (es) | 2017-07-05 |
DK2590521T3 (en) | 2017-04-24 |
EP2590521A1 (en) | 2013-05-15 |
US20130210780A1 (en) | 2013-08-15 |
EP2590521B1 (en) | 2017-02-22 |
US20150290223A1 (en) | 2015-10-15 |
BR112013000446B1 (pt) | 2019-10-29 |
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