BR112012030678A2 - células-tronco da geleia de wharton nativa e sua purificação - Google Patents

células-tronco da geleia de wharton nativa e sua purificação

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Publication number
BR112012030678A2
BR112012030678A2 BR112012030678A BR112012030678A BR112012030678A2 BR 112012030678 A2 BR112012030678 A2 BR 112012030678A2 BR 112012030678 A BR112012030678 A BR 112012030678A BR 112012030678 A BR112012030678 A BR 112012030678A BR 112012030678 A2 BR112012030678 A2 BR 112012030678A2
Authority
BR
Brazil
Prior art keywords
purification
stem cells
wharton jelly
native wharton
native
Prior art date
Application number
BR112012030678A
Other languages
English (en)
Other versions
BR112012030678B1 (pt
Inventor
R Taghizadeh Rouzbeh
Original Assignee
Auxocell Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auxocell Laboratories Inc filed Critical Auxocell Laboratories Inc
Publication of BR112012030678A2 publication Critical patent/BR112012030678A2/pt
Publication of BR112012030678B1 publication Critical patent/BR112012030678B1/pt

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0668Mesenchymal stem cells from other natural sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0037Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
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    • C12N2500/00Specific components of cell culture medium
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/02Coculture with; Conditioned medium produced by embryonic cells
    • C12N2502/025Coculture with; Conditioned medium produced by embryonic cells extra-embryonic cells, e.g. amniotic epithelium, placental cells, Wharton's jelly

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
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  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)

Abstract

células-tronco da geleia de wharton e sua purificação. a presente invenção refere-se às células-tronco da geleia de wharton não cultivadas e os métodos de sua purificação, armazenamento e utilização.
BR112012030678-2A 2010-06-01 2011-06-01 Método para purificação de células-tronco da geleia de wharton e método de cultivo de células-tronco mesenquimais BR112012030678B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35030310P 2010-06-01 2010-06-01
US61/350,303 2010-06-01
PCT/US2011/038710 WO2011153205A1 (en) 2010-06-01 2011-06-01 Native wharton's jelly stem cells and their purification

Publications (2)

Publication Number Publication Date
BR112012030678A2 true BR112012030678A2 (pt) 2017-07-25
BR112012030678B1 BR112012030678B1 (pt) 2021-10-19

Family

ID=44225995

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012030678-2A BR112012030678B1 (pt) 2010-06-01 2011-06-01 Método para purificação de células-tronco da geleia de wharton e método de cultivo de células-tronco mesenquimais

Country Status (12)

Country Link
US (6) US20130121972A1 (pt)
EP (1) EP2576768B1 (pt)
BR (1) BR112012030678B1 (pt)
CA (2) CA2801009C (pt)
CY (1) CY1119382T1 (pt)
DK (1) DK2576768T3 (pt)
ES (1) ES2634545T3 (pt)
LT (1) LT2576768T (pt)
PL (1) PL2576768T3 (pt)
PT (1) PT2576768T (pt)
SG (1) SG185811A1 (pt)
WO (1) WO2011153205A1 (pt)

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SG11201501024QA (en) * 2012-08-15 2015-03-30 Univ Singapore Wound dressing nanomesh impregnated with human umbilical cord wharton's jelly stem cells
JP2017509112A (ja) 2014-02-11 2017-03-30 コーニング インコーポレイテッド 安定化リチウム複合粒子を含むリチウムイオン電池
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
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CN107847526A (zh) 2015-05-20 2018-03-27 组织技术公司 用于预防上皮细胞的增殖和上皮‑间充质转换的组合物和方法
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
CA3015517A1 (en) 2016-03-04 2017-09-08 The Board Of Regents Of The University Of Texas System Devices and methods for umbilical cord processing
EP3589298B1 (fr) * 2017-02-28 2022-06-22 Université de Lorraine Cellules souches mesenchymateuses issues de la gelée de wharton pour le traitement du sepsis
WO2019050882A1 (en) 2017-09-05 2019-03-14 Board Of Regents Of The University Of Texas System DEVICES AND METHODS FOR TREATMENT OF UMBILICAL CORD
EP3909593A1 (en) 2020-05-15 2021-11-17 Rigshospitalet Stem cells for treating skin lesions

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Publication number Publication date
SG185811A1 (en) 2013-01-30
CA3056049A1 (en) 2011-12-08
US20130183273A1 (en) 2013-07-18
CY1119382T1 (el) 2018-02-14
LT2576768T (lt) 2017-08-25
US9012222B2 (en) 2015-04-21
CA2801009C (en) 2021-10-26
DK2576768T3 (en) 2017-08-28
US9920301B2 (en) 2018-03-20
US20130121972A1 (en) 2013-05-16
EP2576768B1 (en) 2017-05-10
WO2011153205A1 (en) 2011-12-08
BR112012030678B1 (pt) 2021-10-19
US20170044490A1 (en) 2017-02-16
US9441201B2 (en) 2016-09-13
US20170107496A1 (en) 2017-04-20
PT2576768T (pt) 2017-08-11
ES2634545T3 (es) 2017-09-28
US20150197728A1 (en) 2015-07-16
EP2576768A1 (en) 2013-04-10
CA2801009A1 (en) 2011-12-08
PL2576768T3 (pl) 2017-10-31
US20200332261A1 (en) 2020-10-22

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B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2725 DE 28-03-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.