BR112012013666A2 - compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm - Google Patents

compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm

Info

Publication number
BR112012013666A2
BR112012013666A2 BR112012013666A BR112012013666A BR112012013666A2 BR 112012013666 A2 BR112012013666 A2 BR 112012013666A2 BR 112012013666 A BR112012013666 A BR 112012013666A BR 112012013666 A BR112012013666 A BR 112012013666A BR 112012013666 A2 BR112012013666 A2 BR 112012013666A2
Authority
BR
Brazil
Prior art keywords
compounds
azabicyclo
hex
processes
preparation
Prior art date
Application number
BR112012013666A
Other languages
English (en)
Portuguese (pt)
Inventor
Alain Dhainaut
Anne-Marie Chollet
Fany Panayi
Jean-Michel Henlin
Patrick Casara
Pierre Lestage
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42711699&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012013666(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of BR112012013666A2 publication Critical patent/BR112012013666A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112012013666A 2009-12-09 2010-12-08 compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm BR112012013666A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0905953A FR2953521B1 (fr) 2009-12-09 2009-12-09 Nouveaux derives azabicyclo[3.1.0]hex-2-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2010/000823 WO2011070253A1 (fr) 2009-12-09 2010-12-08 Derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR112012013666A2 true BR112012013666A2 (pt) 2016-04-19

Family

ID=42711699

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012013666A BR112012013666A2 (pt) 2009-12-09 2010-12-08 compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm

Country Status (32)

Country Link
US (1) US20120283245A1 (enExample)
EP (1) EP2509947A1 (enExample)
JP (1) JP2013513589A (enExample)
KR (1) KR20120102763A (enExample)
CN (1) CN102652127A (enExample)
AP (1) AP2012006352A0 (enExample)
AR (1) AR079265A1 (enExample)
AU (1) AU2010329762B2 (enExample)
BR (1) BR112012013666A2 (enExample)
CA (1) CA2782469C (enExample)
CL (1) CL2012001479A1 (enExample)
CO (1) CO6541535A2 (enExample)
CR (1) CR20120286A (enExample)
CU (1) CU20120091A7 (enExample)
EA (1) EA201200849A1 (enExample)
EC (1) ECSP12011950A (enExample)
FR (1) FR2953521B1 (enExample)
GE (1) GEP20156227B (enExample)
IN (1) IN2012DN04966A (enExample)
MA (1) MA33882B1 (enExample)
MX (1) MX2012006578A (enExample)
NI (1) NI201200099A (enExample)
PE (1) PE20121475A1 (enExample)
PH (1) PH12012501053A1 (enExample)
SA (1) SA110320011B1 (enExample)
SG (1) SG181082A1 (enExample)
TN (1) TN2012000267A1 (enExample)
TW (1) TW201200499A (enExample)
UA (1) UA102950C2 (enExample)
UY (1) UY33072A (enExample)
WO (1) WO2011070253A1 (enExample)
ZA (1) ZA201203943B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105764510A (zh) * 2013-09-09 2016-07-13 赛诺菲 H3受体拮抗剂与胆碱酶抑制剂组合用于阿尔茨海默氏病治疗中的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
BRPI0619233A2 (pt) * 2005-11-30 2011-09-20 Hoffmann La Roche compostos, processo para a sua manufatura, método para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, uso dos compostos e método para o tratamento ou prevenção de obesidade e de diabetes do tipo ii em um ser humano ou animal

Also Published As

Publication number Publication date
WO2011070253A1 (fr) 2011-06-16
MA33882B1 (fr) 2013-01-02
CO6541535A2 (es) 2012-10-16
US20120283245A1 (en) 2012-11-08
EA201200849A1 (ru) 2013-01-30
ECSP12011950A (es) 2012-07-31
TN2012000267A1 (fr) 2013-12-12
JP2013513589A (ja) 2013-04-22
NI201200099A (es) 2012-11-09
PH12012501053A1 (en) 2013-02-04
MX2012006578A (es) 2012-06-25
CR20120286A (es) 2012-08-20
CA2782469C (fr) 2014-04-08
CN102652127A (zh) 2012-08-29
SA110320011B1 (ar) 2013-10-01
FR2953521B1 (fr) 2011-11-18
AU2010329762B2 (en) 2013-10-03
AU2010329762A1 (en) 2012-06-21
UY33072A (es) 2011-05-31
FR2953521A1 (fr) 2011-06-10
AR079265A1 (es) 2012-01-04
TW201200499A (en) 2012-01-01
SG181082A1 (en) 2012-07-30
UA102950C2 (ru) 2013-08-27
KR20120102763A (ko) 2012-09-18
EP2509947A1 (fr) 2012-10-17
GEP20156227B (en) 2015-01-26
CU20120091A7 (es) 2012-07-31
AP2012006352A0 (en) 2012-08-31
WO2011070253A8 (fr) 2012-08-02
ZA201203943B (en) 2013-08-28
CL2012001479A1 (es) 2013-02-08
CA2782469A1 (fr) 2011-06-16
IN2012DN04966A (enExample) 2015-09-25
PE20121475A1 (es) 2012-10-20

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2373 DE 28-06-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.