BR112012013666A2 - compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm - Google Patents

compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm

Info

Publication number
BR112012013666A2
BR112012013666A2 BR112012013666A BR112012013666A BR112012013666A2 BR 112012013666 A2 BR112012013666 A2 BR 112012013666A2 BR 112012013666 A BR112012013666 A BR 112012013666A BR 112012013666 A BR112012013666 A BR 112012013666A BR 112012013666 A2 BR112012013666 A2 BR 112012013666A2
Authority
BR
Brazil
Prior art keywords
compounds
azabicyclo
hex
processes
preparation
Prior art date
Application number
BR112012013666A
Other languages
English (en)
Portuguese (pt)
Inventor
Alain Dhainaut
Anne-Marie Chollet
Fany Panayi
Jean-Michel Henlin
Patrick Casara
Pierre Lestage
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42711699&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012013666(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of BR112012013666A2 publication Critical patent/BR112012013666A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112012013666A 2009-12-09 2010-12-08 compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm BR112012013666A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0905953A FR2953521B1 (fr) 2009-12-09 2009-12-09 Nouveaux derives azabicyclo[3.1.0]hex-2-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2010/000823 WO2011070253A1 (fr) 2009-12-09 2010-12-08 Derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR112012013666A2 true BR112012013666A2 (pt) 2016-04-19

Family

ID=42711699

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012013666A BR112012013666A2 (pt) 2009-12-09 2010-12-08 compostos de azabiciclo[3.1.0]hex-2-ila, processo para sua preparação e composições farmacêuticas que os contêm

Country Status (32)

Country Link
US (1) US20120283245A1 (enExample)
EP (1) EP2509947A1 (enExample)
JP (1) JP2013513589A (enExample)
KR (1) KR20120102763A (enExample)
CN (1) CN102652127A (enExample)
AP (1) AP2012006352A0 (enExample)
AR (1) AR079265A1 (enExample)
AU (1) AU2010329762B2 (enExample)
BR (1) BR112012013666A2 (enExample)
CA (1) CA2782469C (enExample)
CL (1) CL2012001479A1 (enExample)
CO (1) CO6541535A2 (enExample)
CR (1) CR20120286A (enExample)
CU (1) CU20120091A7 (enExample)
EA (1) EA201200849A1 (enExample)
EC (1) ECSP12011950A (enExample)
FR (1) FR2953521B1 (enExample)
GE (1) GEP20156227B (enExample)
IN (1) IN2012DN04966A (enExample)
MA (1) MA33882B1 (enExample)
MX (1) MX2012006578A (enExample)
NI (1) NI201200099A (enExample)
PE (1) PE20121475A1 (enExample)
PH (1) PH12012501053A1 (enExample)
SA (1) SA110320011B1 (enExample)
SG (1) SG181082A1 (enExample)
TN (1) TN2012000267A1 (enExample)
TW (1) TW201200499A (enExample)
UA (1) UA102950C2 (enExample)
UY (1) UY33072A (enExample)
WO (1) WO2011070253A1 (enExample)
ZA (1) ZA201203943B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016529307A (ja) * 2013-09-09 2016-09-23 サノフイ アルツハイマー病の処置に使用するためのｈ３受容体アンタゴニスト

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
ATE466007T1 (de) * 2005-11-30 2010-05-15 Hoffmann La Roche 5-substituierte indol-2-carbonsäureamidderivate

Also Published As

Publication number Publication date
WO2011070253A8 (fr) 2012-08-02
EP2509947A1 (fr) 2012-10-17
SG181082A1 (en) 2012-07-30
CA2782469C (fr) 2014-04-08
AU2010329762A1 (en) 2012-06-21
ECSP12011950A (es) 2012-07-31
WO2011070253A1 (fr) 2011-06-16
AP2012006352A0 (en) 2012-08-31
IN2012DN04966A (enExample) 2015-09-25
JP2013513589A (ja) 2013-04-22
GEP20156227B (en) 2015-01-26
EA201200849A1 (ru) 2013-01-30
CU20120091A7 (es) 2012-07-31
CN102652127A (zh) 2012-08-29
CL2012001479A1 (es) 2013-02-08
FR2953521A1 (fr) 2011-06-10
AU2010329762B2 (en) 2013-10-03
ZA201203943B (en) 2013-08-28
AR079265A1 (es) 2012-01-04
US20120283245A1 (en) 2012-11-08
TN2012000267A1 (fr) 2013-12-12
CR20120286A (es) 2012-08-20
FR2953521B1 (fr) 2011-11-18
TW201200499A (en) 2012-01-01
PH12012501053A1 (en) 2013-02-04
UA102950C2 (ru) 2013-08-27
SA110320011B1 (ar) 2013-10-01
CO6541535A2 (es) 2012-10-16
MX2012006578A (es) 2012-06-25
PE20121475A1 (es) 2012-10-20
NI201200099A (es) 2012-11-09
CA2782469A1 (fr) 2011-06-16
KR20120102763A (ko) 2012-09-18
MA33882B1 (fr) 2013-01-02
UY33072A (es) 2011-05-31

Similar Documents

Publication Publication Date Title
EA201170772A1 (ru) Органические соединения
EA201001205A1 (ru) Соединения, содержащие циклобутоксигруппу
BRPI0910388A2 (pt) agentes terapêutico antivirais.
BRPI0608604B8 (pt) moduladores de 2,3-dioxigenase de indolamina e composição farmacêutica
BR112017027831A2 (pt) derivados de hidroxiácido, um processo para sua preparação e composições farmacêuticas contendo-os
BR112013000254A2 (pt) derivados heterocíclicos 1-fenil-substituídos e seu uso como moduladores do receptor de prostaglandina d2
EA201190235A1 (ru) Замещенные 1-цианоэтилгетероциклилкарбоксамидные соединения 750
ECSP088854A (es) Moduladores bencimidazolicos de vr1
BR112012027034A2 (pt) inibidores da arginase e suas aplicações terapêuticas
UY32174A (es) Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones
BR112014018879A8 (pt) Composto e composição farmacêutica e combinação compreendendo dito composto
BR112018075433A2 (pt) derivados de piperidinila, processo para sua preparação e composições farmacêuticas contendo-os
BR112015014372A2 (pt) inibidores de autotaxina
EA201401193A1 (ru) Триарильные соединения и композиции, их содержащие
BR112013030391A2 (pt) derivados de piperidina 3- espirocíclicos como agonistas dos receptores de grelina
BRPI0900983A2 (pt) compostos de diometina, processo para sua preparação e composições farmacêuticas contendo os mesmos
BRPI0911404A2 (pt) Derivados de pirano, sua preparação e uso dos mesmos em perfumaria
MX2010008051A (es) Nuevos derivados de fluoroglicosidos aromaticos, productos farmaceuticos que comprenden dichos compuestos y uso de los mismos.
UY32744A (es) Derivados de 2-carboxamida-7-piperazinil-benzofurano 774
EA201001855A1 (ru) Соединения, содержащие циклобутоксигруппу
BRPI0915513B8 (pt) compostos derivados de ácido fenóxi-cromano carboxílico 6-substituído, composições farmacêuticas compreendendo os referidos compostos, uso dos mesmos, e processo para a preparação destes
BRPI0909737A2 (pt) compostos de pirrolidinila, composição farmacêutica compreendendo os mesmos e usos dos mesmos
CY1115734T1 (el) Συνθεσεις benzenesulfonamide, μεθοδος συνθεσης τους, και χρηση αυτων στην ιατρικη
BR112015015229A8 (pt) processo para a preparação de um composto da fórmula, e, composto
EA201000340A1 (ru) Аминобензилзамещенные циклические сульфоны, полезные в качестве ингибиторов васе

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2373 DE 28-06-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.