CR20120286A - Nuevos derivados de azabiciclo[3.1.0]hex-2-ilo, su procedimiento de preparación y las composiciones farmacéuticas que los contienen - Google Patents

Nuevos derivados de azabiciclo[3.1.0]hex-2-ilo, su procedimiento de preparación y las composiciones farmacéuticas que los contienen

Info

Publication number
CR20120286A
CR20120286A CR20120286A CR20120286A CR20120286A CR 20120286 A CR20120286 A CR 20120286A CR 20120286 A CR20120286 A CR 20120286A CR 20120286 A CR20120286 A CR 20120286A CR 20120286 A CR20120286 A CR 20120286A
Authority
CR
Costa Rica
Prior art keywords
azabiciclo
ilo
hex
pharmaceutical compositions
compositions containing
Prior art date
Application number
CR20120286A
Other languages
English (en)
Inventor
Anne-Marie Chollet
Alain Dhainaut
Jean-Michel Henlin
Pierre Lestage
Fany Panayi
Patrick Casara
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42711699&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20120286(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of CR20120286A publication Critical patent/CR20120286A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compuestos de la fórmula I, en la que ALK representa una cadena alquileno, W representa un grupo de la fórmula II o de la fórmula III, en la que R y R' son tales como se han definido en la descripción.
CR20120286A 2009-12-09 2012-05-29 Nuevos derivados de azabiciclo[3.1.0]hex-2-ilo, su procedimiento de preparación y las composiciones farmacéuticas que los contienen CR20120286A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0905953A FR2953521B1 (fr) 2009-12-09 2009-12-09 Nouveaux derives azabicyclo[3.1.0]hex-2-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
CR20120286A true CR20120286A (es) 2012-08-20

Family

ID=42711699

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120286A CR20120286A (es) 2009-12-09 2012-05-29 Nuevos derivados de azabiciclo[3.1.0]hex-2-ilo, su procedimiento de preparación y las composiciones farmacéuticas que los contienen

Country Status (31)

Country Link
US (1) US20120283245A1 (es)
EP (1) EP2509947A1 (es)
JP (1) JP2013513589A (es)
KR (1) KR20120102763A (es)
CN (1) CN102652127A (es)
AP (1) AP2012006352A0 (es)
AR (1) AR079265A1 (es)
AU (1) AU2010329762B2 (es)
BR (1) BR112012013666A2 (es)
CA (1) CA2782469C (es)
CL (1) CL2012001479A1 (es)
CO (1) CO6541535A2 (es)
CR (1) CR20120286A (es)
CU (1) CU20120091A7 (es)
EA (1) EA201200849A1 (es)
EC (1) ECSP12011950A (es)
FR (1) FR2953521B1 (es)
GE (1) GEP20156227B (es)
IN (1) IN2012DN04966A (es)
MA (1) MA33882B1 (es)
MX (1) MX2012006578A (es)
NI (1) NI201200099A (es)
PE (1) PE20121475A1 (es)
SA (1) SA110320011B1 (es)
SG (1) SG181082A1 (es)
TN (1) TN2012000267A1 (es)
TW (1) TW201200499A (es)
UA (1) UA102950C2 (es)
UY (1) UY33072A (es)
WO (1) WO2011070253A1 (es)
ZA (1) ZA201203943B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160048930A (ko) * 2013-09-09 2016-05-04 사노피 알츠하이머 질환의 치료에 사용하기 위해 콜린에스테라제 저해제와 조합된 h3 수용체 길항제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
BRPI0619233A2 (pt) * 2005-11-30 2011-09-20 Hoffmann La Roche compostos, processo para a sua manufatura, método para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, uso dos compostos e método para o tratamento ou prevenção de obesidade e de diabetes do tipo ii em um ser humano ou animal

Also Published As

Publication number Publication date
CN102652127A (zh) 2012-08-29
CU20120091A7 (es) 2012-07-31
FR2953521B1 (fr) 2011-11-18
CL2012001479A1 (es) 2013-02-08
MA33882B1 (fr) 2013-01-02
AP2012006352A0 (en) 2012-08-31
CO6541535A2 (es) 2012-10-16
UY33072A (es) 2011-05-31
SG181082A1 (en) 2012-07-30
ECSP12011950A (es) 2012-07-31
GEP20156227B (en) 2015-01-26
WO2011070253A1 (fr) 2011-06-16
EP2509947A1 (fr) 2012-10-17
ZA201203943B (en) 2013-08-28
PE20121475A1 (es) 2012-10-20
KR20120102763A (ko) 2012-09-18
EA201200849A1 (ru) 2013-01-30
WO2011070253A8 (fr) 2012-08-02
AR079265A1 (es) 2012-01-04
AU2010329762B2 (en) 2013-10-03
AU2010329762A1 (en) 2012-06-21
SA110320011B1 (ar) 2013-10-01
JP2013513589A (ja) 2013-04-22
MX2012006578A (es) 2012-06-25
BR112012013666A2 (pt) 2016-04-19
TN2012000267A1 (fr) 2013-12-12
CA2782469A1 (fr) 2011-06-16
FR2953521A1 (fr) 2011-06-10
NI201200099A (es) 2012-11-09
UA102950C2 (ru) 2013-08-27
US20120283245A1 (en) 2012-11-08
IN2012DN04966A (es) 2015-09-25
TW201200499A (en) 2012-01-01
CA2782469C (fr) 2014-04-08

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