BR0316256A - Métodos de inibir a produção de tnf-alfa e a atividade de pde4, de tratar ou prevenir uma doença ou um distúrbio, de controlar os nìveis de camp em uma célula e de produzir um composto, composição farmacêutica e composto - Google Patents

Métodos de inibir a produção de tnf-alfa e a atividade de pde4, de tratar ou prevenir uma doença ou um distúrbio, de controlar os nìveis de camp em uma célula e de produzir um composto, composição farmacêutica e composto

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Publication number
BR0316256A
BR0316256A BR0316256-7A BR0316256A BR0316256A BR 0316256 A BR0316256 A BR 0316256A BR 0316256 A BR0316256 A BR 0316256A BR 0316256 A BR0316256 A BR 0316256A
Authority
BR
Brazil
Prior art keywords
compound
treating
methods
preventing
disorder
Prior art date
Application number
BR0316256-7A
Other languages
English (en)
Portuguese (pt)
Inventor
George W Muller
Roger Shen-Chu Chen
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of BR0316256A publication Critical patent/BR0316256A/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
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    • A61P31/20—Antivirals for DNA viruses
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    • A61P33/00—Antiparasitic agents
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
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  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
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  • Physical Education & Sports Medicine (AREA)
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  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
BR0316256-7A 2002-11-18 2003-11-17 Métodos de inibir a produção de tnf-alfa e a atividade de pde4, de tratar ou prevenir uma doença ou um distúrbio, de controlar os nìveis de camp em uma célula e de produzir um composto, composição farmacêutica e composto BR0316256A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42738002P 2002-11-18 2002-11-18
PCT/US2003/036741 WO2004054501A2 (en) 2002-11-18 2003-11-17 Methods of usig and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide

Publications (1)

Publication Number Publication Date
BR0316256A true BR0316256A (pt) 2005-10-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR0316256-7A BR0316256A (pt) 2002-11-18 2003-11-17 Métodos de inibir a produção de tnf-alfa e a atividade de pde4, de tratar ou prevenir uma doença ou um distúrbio, de controlar os nìveis de camp em uma célula e de produzir um composto, composição farmacêutica e composto

Country Status (13)

Country Link
US (1) US20040167199A1 (enExample)
EP (1) EP1569599A2 (enExample)
JP (1) JP2006515844A (enExample)
KR (1) KR20050086715A (enExample)
CN (1) CN1738614A (enExample)
AU (1) AU2003294312A1 (enExample)
BR (1) BR0316256A (enExample)
CA (1) CA2506442A1 (enExample)
MX (1) MXPA05005161A (enExample)
NZ (1) NZ540546A (enExample)
TW (1) TW200415143A (enExample)
WO (1) WO2004054501A2 (enExample)
ZA (1) ZA200503926B (enExample)

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WO2004054501A2 (en) 2004-07-01
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MXPA05005161A (es) 2005-07-22
ZA200503926B (en) 2006-08-30
AU2003294312A1 (en) 2004-07-09
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NZ540546A (en) 2008-03-28

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