BR0311451A - Composição tamponada de nicotina lìquida para administração pulmonar - Google Patents

Composição tamponada de nicotina lìquida para administração pulmonar

Info

Publication number
BR0311451A
BR0311451A BR0311451-1A BR0311451A BR0311451A BR 0311451 A BR0311451 A BR 0311451A BR 0311451 A BR0311451 A BR 0311451A BR 0311451 A BR0311451 A BR 0311451A
Authority
BR
Brazil
Prior art keywords
administration
preparation
nicotine
pulmonary administration
liquid nicotine
Prior art date
Application number
BR0311451-1A
Other languages
English (en)
Inventor
Sven-Borje Andersson
Folke Moren
Elisabeth Sthengel
Kristina Thyresson
Mark P Warchol
Original Assignee
Pfizer Health Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Health Ab filed Critical Pfizer Health Ab
Publication of BR0311451A publication Critical patent/BR0311451A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Abstract

"COMPOSIçãO TAMPONADA DE NICOTINA LìQUIDA PARA ADMINISTRAçãO PULMONAR". A composição consiste em um preparado farmacêutico líquido compreendendo nicotina em qualquer forma para a administração essencialmente aos pulmões. o preparado é acidificado e/ou alcalinizado por tamponamento e por regulagem do pH, o que proporciona uma t~ max~ de nicotina no sangue arterial de um paciente dentro de um breve período de tempo depois da administração. A administração abrange, de preferência, a pulverização de um aerossol para dentro da cavidade oral para uma distribuição subseq³ente, essencialmente aos pulmões. Um processo para a fabricação do preparado é também incluído, assim como o emprego do preparado em terapia, tal como para o tratamento do vício do tabagismo.
BR0311451-1A 2002-06-03 2003-05-30 Composição tamponada de nicotina lìquida para administração pulmonar BR0311451A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0201669A SE0201669D0 (sv) 2002-06-03 2002-06-03 New formulation and use thereof
PCT/SE2003/000890 WO2003101454A1 (en) 2002-06-03 2003-05-30 A buffered, liquid nicotine composition for pulmonary administration

Publications (1)

Publication Number Publication Date
BR0311451A true BR0311451A (pt) 2005-03-15

Family

ID=20288046

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0311451-1A BR0311451A (pt) 2002-06-03 2003-05-30 Composição tamponada de nicotina lìquida para administração pulmonar

Country Status (19)

Country Link
EP (1) EP1509227B9 (pt)
JP (2) JP4745658B2 (pt)
CN (1) CN100500148C (pt)
AR (1) AR039947A1 (pt)
AT (1) ATE444753T1 (pt)
AU (1) AU2003243074B2 (pt)
BR (1) BR0311451A (pt)
CA (1) CA2487699C (pt)
DE (1) DE60329592D1 (pt)
DK (1) DK1509227T3 (pt)
ES (1) ES2332405T3 (pt)
IL (1) IL165195A0 (pt)
MX (1) MXPA04012041A (pt)
NZ (1) NZ536863A (pt)
RU (1) RU2283111C2 (pt)
SE (1) SE0201669D0 (pt)
TW (1) TW200407142A (pt)
WO (1) WO2003101454A1 (pt)
ZA (1) ZA200409793B (pt)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
SE521512C2 (sv) 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
EP1578422B1 (en) 2002-12-20 2007-04-11 NicoNovum AB A physically and chemically stable nicotine and micorcrystalline cellulose containing particulate material
CN100381083C (zh) 2003-04-29 2008-04-16 韩力 一种非可燃性电子喷雾香烟
CN2719043Y (zh) 2004-04-14 2005-08-24 韩力 雾化电子烟
EP2530075A3 (en) 2004-06-24 2014-12-24 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
US20160345631A1 (en) 2005-07-19 2016-12-01 James Monsees Portable devices for generating an inhalable vapor
AU2006332726B2 (en) 2005-12-28 2012-12-13 Vertex Pharmaceuticals Incorporated. Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
WO2007104573A2 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
CN201067079Y (zh) 2006-05-16 2008-06-04 韩力 仿真气溶胶吸入器
EP2222304A2 (en) * 2007-09-14 2010-09-01 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
AT507187B1 (de) 2008-10-23 2010-03-15 Helmut Dr Buchberger Inhalator
CN201379072Y (zh) 2009-02-11 2010-01-13 韩力 一种改进的雾化电子烟
SG10201504084QA (en) 2009-03-20 2015-06-29 Vertex Pharma Process for making modulators of cystic fibrosis transmembrane conductance regulator
NZ599060A (en) * 2009-09-16 2014-10-31 Philip Morris Products Sa Improved device and method for delivery of a medicament
AT510837B1 (de) 2011-07-27 2012-07-15 Helmut Dr Buchberger Inhalatorkomponente
HUE026804T2 (en) 2011-02-11 2016-07-28 Batmark Ltd Inhaler component
US8903228B2 (en) 2011-03-09 2014-12-02 Chong Corporation Vapor delivery devices and methods
US9399110B2 (en) 2011-03-09 2016-07-26 Chong Corporation Medicant delivery system
EP3178510B1 (en) 2011-03-09 2018-08-01 Chong Corporation Medicant delivery system
RU2595971C2 (ru) 2011-09-06 2016-08-27 Бритиш Америкэн Тобэкко (Инвестментс) Лимитед Нагревание курительного материала
CA3162870A1 (en) 2011-09-06 2013-03-14 Nicoventures Trading Limited Heating smokable material
AT511344B1 (de) 2011-10-21 2012-11-15 Helmut Dr Buchberger Inhalatorkomponente
US9907748B2 (en) * 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
CN109966264A (zh) 2012-02-27 2019-07-05 沃泰克斯药物股份有限公司 药物组合物及其施用
GB201207039D0 (en) 2012-04-23 2012-06-06 British American Tobacco Co Heating smokeable material
GB2504076A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
GB201215282D0 (en) 2012-08-28 2012-10-10 Kind Consumer Ltd An inhaler
GB201215273D0 (en) * 2012-08-28 2012-10-10 Kind Consumer Ltd Nicotine composition
US10279934B2 (en) 2013-03-15 2019-05-07 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
GB2513639A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2513637A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
KR102490695B1 (ko) * 2013-05-06 2023-01-19 쥴 랩스, 인크. 에어로졸 장치를 위한 니코틴 염 제제 및 그 방법
GB2514893B (en) 2013-06-04 2017-12-06 Nicoventures Holdings Ltd Container
US10251422B2 (en) 2013-07-22 2019-04-09 Altria Client Services Llc Electronic smoking article
PL3498115T3 (pl) 2013-12-23 2021-12-20 Juul Labs International Inc. Systemy urządzeń do odparowywania
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
GB201407426D0 (en) 2014-04-28 2014-06-11 Batmark Ltd Aerosol forming component
US9896429B2 (en) 2014-05-27 2018-02-20 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US9738622B2 (en) * 2014-05-27 2017-08-22 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US10508096B2 (en) 2014-05-27 2019-12-17 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
GB2528673B (en) 2014-07-25 2020-07-01 Nicoventures Holdings Ltd Aerosol provision system
WO2016057730A1 (en) 2014-10-07 2016-04-14 Strohmeier Mark Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
GB2535427A (en) * 2014-11-07 2016-08-24 Nicoventures Holdings Ltd Solution
GB2532062A (en) * 2014-11-07 2016-05-11 Nicoventures Holdings Ltd Container
CN112155255A (zh) 2014-12-05 2021-01-01 尤尔实验室有限公司 校正剂量控制
GB2533135B (en) 2014-12-11 2020-11-11 Nicoventures Holdings Ltd Aerosol provision systems
GB201511349D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic aerosol provision systems
US20170055584A1 (en) 2015-08-31 2017-03-02 British American Tobacco (Investments) Limited Article for use with apparatus for heating smokable material
US11924930B2 (en) 2015-08-31 2024-03-05 Nicoventures Trading Limited Article for use with apparatus for heating smokable material
GB201516729D0 (en) * 2015-09-22 2015-11-04 The Technology Partnership Plc Liquid nicotine formulation
CN114656446A (zh) * 2015-11-25 2022-06-24 R.J.雷诺兹烟草公司 烟碱盐、共晶体和盐共晶体配合物
US9867397B2 (en) 2016-01-11 2018-01-16 Patrick Beymer Nicotine delivery system
DE202017007467U1 (de) 2016-02-11 2021-12-08 Juul Labs, Inc. Befüllbare Verdampferkartusche
MX2018009703A (es) 2016-02-11 2019-07-08 Juul Labs Inc Cartuchos de fijacion segura para dispositivos vaporizadores.
CN109069497A (zh) * 2016-02-29 2018-12-21 尼古珍有限公司 尼古丁制剂和气雾剂
US10405582B2 (en) 2016-03-10 2019-09-10 Pax Labs, Inc. Vaporization device with lip sensing
RU2708249C1 (ru) 2016-04-27 2019-12-05 Никовенчерс Холдингз Лимитед Электронная система образования аэрозоля и испаритель для такой системы
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD848057S1 (en) 2016-06-23 2019-05-07 Pax Labs, Inc. Lid for a vaporizer
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
JP2020525047A (ja) * 2017-06-26 2020-08-27 ヌード ニコチン, インコーポレイテッドNude Nicotine, Inc. ニコチン塩およびその製造方法および使用方法
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
EP3574902A1 (en) * 2018-06-01 2019-12-04 Yatzz Limited Nicotine formulation and mode of delivery
GB201817859D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817864D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817867D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817863D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
EP3856304B1 (en) 2019-12-15 2023-11-08 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US11730191B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
WO2021123867A1 (en) 2019-12-15 2021-06-24 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
US11589610B2 (en) 2019-12-15 2023-02-28 Shaheen Innovations Holding Limited Nicotine delivery device having a mist generator device and a driver device
AU2020410172B2 (en) 2019-12-15 2023-02-23 Shaheen Innovations Holding Limited Mist inhaler devices
EP3860696B1 (en) 2019-12-15 2024-04-10 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US11666713B2 (en) 2019-12-15 2023-06-06 Shaheen Innovations Holding Limited Mist inhaler devices
US20230188901A1 (en) 2021-12-15 2023-06-15 Shaheen Innovations Holding Limited Apparatus for transmitting ultrasonic waves

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2030862A (en) * 1978-04-10 1980-04-16 Smith A A composition for treating drug addiction such as smoking nicotine-containing products
DE3241437A1 (de) * 1982-11-10 1984-05-10 Ferdinand Prof. Dr.med. 6901 Wilhelmsfeld Schmidt Mittel zum zwecke der raucherentwoehnung und/oder fuer nebenwirkungsfreien nikotingenuss bei suchtrauchern
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
US4953572A (en) * 1985-04-25 1990-09-04 Rose Jed E Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US4920989A (en) * 1985-04-25 1990-05-01 Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
GB9200047D0 (en) * 1992-01-03 1992-02-26 Univ Alberta Nicotine-containing nasal spray

Also Published As

Publication number Publication date
CA2487699C (en) 2012-04-17
ES2332405T3 (es) 2010-02-04
RU2004139067A (ru) 2005-08-10
JP4745658B2 (ja) 2011-08-10
CN1658876A (zh) 2005-08-24
ATE444753T1 (de) 2009-10-15
EP1509227B9 (en) 2010-05-19
WO2003101454A1 (en) 2003-12-11
CA2487699A1 (en) 2003-12-11
TW200407142A (en) 2004-05-16
EP1509227B1 (en) 2009-10-07
EP1509227A1 (en) 2005-03-02
AR039947A1 (es) 2005-03-09
DE60329592D1 (de) 2009-11-19
AU2003243074A1 (en) 2003-12-19
IL165195A0 (en) 2005-12-18
JP5430525B2 (ja) 2014-03-05
SE0201669D0 (sv) 2002-06-03
ZA200409793B (en) 2006-08-30
JP2005533770A (ja) 2005-11-10
DK1509227T3 (da) 2010-02-01
RU2283111C2 (ru) 2006-09-10
MXPA04012041A (es) 2005-08-16
AU2003243074B2 (en) 2008-11-20
CN100500148C (zh) 2009-06-17
JP2010280721A (ja) 2010-12-16
NZ536863A (en) 2007-05-31

Similar Documents

Publication Publication Date Title
BR0311451A (pt) Composição tamponada de nicotina lìquida para administração pulmonar
BR0215393A (pt) Formulação farmacêutica lìquida, compreendendo nicotina, para administração na cavidade oral
BRPI0515932A (pt) composições e métodos para distribuição intranasal, bucal, sublingual e pulmonar de vareniclina
NO20054767L (no) Sammensetninger omfattende apomorfin for inhalering i lunge
RS20090105A (en) Medicament compositions based on tiotropium salts and on salmetrol salts
SG169233A1 (en) Pharmaceutical compositions comprising apomorphine for pulmonary inhalation
ATE268179T1 (de) Verwendung von substituierten imidazo (1,2- a)pyridin-, -pyrimidin- und -pyrazin-3-yl-amin- derivaten zur herstellung von medikamenten zur nos-inhibierung
BR0109875A (pt) Tratamento de doenças respiratórias
BR0315868A (pt) Método para tratar ou melhorar infecção pulmonar em um paciente portador de fibrose cìstica; e método para tratar ou melhorar infecção pulmonar em um animal
DE602004017127D1 (de) Langandauernde, aromatisierte darreichungsform zur verlängerten freisetzung von aktivstoffen im mund
ATE513557T1 (de) Verfahren zur behandlung von krankheiten des menschen im zusammenhang mit einem erhöhten desoxyribonucleinsäuregehalt in extrazellulären räumen von geweben und medizinische zubereitung zur durchführung des verfahrens
GEP20043269B (en) Purine Derivatives, Method for Their Production and Composition Containing the Same
BR9906813A (pt) Método para administração de insulina aspb28- humana
WO2003032815A3 (en) Medical device for delivering patches
SE0102276D0 (sv) Device and method for the administration of a medicament
BR0111591A (pt) Compostos, composição farmacêutica, e, métodos para elevar o nìvel de plasma do hormÈnio de crescimento em um mamìfero, para o tratamento de deficiência da secreção do hormÈnio de crescimento, para o tratamento do retardo do crescimento em crianças, para o tratamento de distúrbios metabólicos associados com a deficiência da secreção do hormÈnio de crescimento, em particular em pacientes idosos, e para promover a cura de ferimentos, recupeção de cirurgia ou recuperação de doenças debilitantes
BR0107983A (pt) Uso de pramipexol para o tratamento de enfermidades decorrentes de vìcios
ATE353645T1 (de) Verwendung von 2-oxo-1-pyrrolidin-derivaten zur herstellung eines arzneimittels zur behandlung von dyskinesia
WO2003079993A3 (en) hGH (HUMAN GROWTH HORMONE) FORMULATIONS FOR PULMONARY ADMINISTRATION
CO5261512A1 (es) Metodo y composiciones para el tratamiento de las enfermedades pulmonares
BRPI0409387B8 (pt) complexo de alvejamento de tecido mole de tório-227 e um agente complexante, uso do mesmo, composição farmacêutica, método para a formação de um complexo, e, kit para uso em um método para o tratamento de doença de tecido mole em um indivíduo mamífero
BR9914945A (pt) Processo para proporcionar terapiacosmética/medicinal
Kulkarni et al. A new flexible laryngeal mask airway introducer
MXPA02009603A (es) Terapias de dosis divididas con actividad de deterioro vascular.
ATE452639T1 (de) Arzneimittelkompositionen aus tiotropiumsalzen und epinastin zur therapie von atemswegserkrankungen

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: MCNEIL AB (SE)

Free format text: TRANSFERIDO DE: PFIZER HEALTH AB

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8 E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.