BR0308431A - Parecoxib sódico cristalino - Google Patents
Parecoxib sódico cristalinoInfo
- Publication number
- BR0308431A BR0308431A BR0308431-0A BR0308431A BR0308431A BR 0308431 A BR0308431 A BR 0308431A BR 0308431 A BR0308431 A BR 0308431A BR 0308431 A BR0308431 A BR 0308431A
- Authority
- BR
- Brazil
- Prior art keywords
- parecoxib
- unsolvated
- slurry
- crystalline
- parecoxib sodium
- Prior art date
Links
- 229960004662 parecoxib Drugs 0.000 title abstract 2
- TZRHLKRLEZJVIJ-UHFFFAOYSA-N parecoxib Chemical compound C1=CC(S(=O)(=O)NC(=O)CC)=CC=C1C1=C(C)ON=C1C1=CC=CC=C1 TZRHLKRLEZJVIJ-UHFFFAOYSA-N 0.000 title abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- 229960003925 parecoxib sodium Drugs 0.000 abstract 3
- 239000002002 slurry Substances 0.000 abstract 3
- ICJGKYTXBRDUMV-UHFFFAOYSA-N trichloro(6-trichlorosilylhexyl)silane Chemical compound Cl[Si](Cl)(Cl)CCCCCC[Si](Cl)(Cl)Cl ICJGKYTXBRDUMV-UHFFFAOYSA-N 0.000 abstract 3
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 2
- 229940088679 drug related substance Drugs 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36456702P | 2002-03-15 | 2002-03-15 | |
| US41798702P | 2002-10-11 | 2002-10-11 | |
| PCT/US2003/007484 WO2003078408A1 (en) | 2002-03-15 | 2003-03-12 | Crystalline parecoxib sodium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0308431A true BR0308431A (pt) | 2005-01-18 |
Family
ID=28045416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0308431-0A BR0308431A (pt) | 2002-03-15 | 2003-03-12 | Parecoxib sódico cristalino |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20030232871A1 (https=) |
| EP (1) | EP1485362A1 (https=) |
| JP (1) | JP2005529084A (https=) |
| KR (1) | KR100763045B1 (https=) |
| CN (1) | CN1642926A (https=) |
| AR (1) | AR038985A1 (https=) |
| AU (1) | AU2003220180A1 (https=) |
| BR (1) | BR0308431A (https=) |
| CA (1) | CA2478500A1 (https=) |
| CO (1) | CO5631437A2 (https=) |
| IL (1) | IL163780A0 (https=) |
| MX (1) | MXPA04008932A (https=) |
| MY (1) | MY148518A (https=) |
| NZ (1) | NZ535951A (https=) |
| PL (1) | PL372880A1 (https=) |
| RU (1) | RU2300529C2 (https=) |
| TW (1) | TW200400949A (https=) |
| WO (1) | WO2003078408A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050143431A1 (en) * | 2003-04-04 | 2005-06-30 | Hetero Drugs Limited | Novel crystalline forms of parecoxib sodium |
| CA2540895C (en) * | 2003-10-02 | 2016-08-02 | Elan Pharmaceuticals, Inc. | Combinations of ziconotide and opioids for reducing pain |
| CA2551523A1 (en) * | 2003-12-24 | 2005-07-21 | Pharmacia Corporation | Metal salts of parecoxib as prodrugs of the cox-2 inhibitor valdecoxib for the treatment of inflammation, pain and/or fever |
| ITMI20040019A1 (it) * | 2004-01-12 | 2004-04-12 | Univ Bari | Derivati isossazolici e loro impiego come inibitori della ciclossigenasi |
| US7796785B2 (en) * | 2005-03-03 | 2010-09-14 | Fujifilm Corporation | Image extracting apparatus, image extracting method, and image extracting program |
| US20080108664A1 (en) | 2005-12-23 | 2008-05-08 | Liu Belle B | Solid-state form of AMG 706 and pharmaceutical compositions thereof |
| US7989450B2 (en) | 2008-01-11 | 2011-08-02 | Universita' Degli Studi Di Bari | Functionalized diarylisoxazoles inhibitors of ciclooxygenase |
| GB0919757D0 (en) * | 2009-11-12 | 2009-12-30 | Johnson Matthey Plc | Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs |
| US8299295B2 (en) * | 2009-10-15 | 2012-10-30 | Johnson Matthey Public Limited Company | Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs |
| CN105726496B (zh) * | 2014-12-12 | 2019-05-28 | 湖南科伦药物研究有限公司 | 一种帕瑞昔布钠冻干粉剂、其制备方法及其粉剂产品 |
| CN105125506A (zh) * | 2015-08-18 | 2015-12-09 | 上海秀新臣邦医药科技有限公司 | 一种注射用帕瑞昔布钠及其制备方法 |
| CN106580893A (zh) * | 2016-12-26 | 2017-04-26 | 上药东英（江苏）药业有限公司 | 一种帕瑞昔布钠冻干粉针制剂 |
| CN106692079A (zh) * | 2016-12-26 | 2017-05-24 | 上药东英（江苏）药业有限公司 | 一种帕瑞昔布钠长效冻干粉针制剂 |
| CN117003769B (zh) * | 2023-07-11 | 2024-11-22 | 中国科学院宁波材料技术与工程研究所 | 氯诺昔康复合物、氯诺昔康-小檗碱共晶及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE233743T1 (de) | 1996-04-12 | 2003-03-15 | Searle & Co | N-((4-(5-methyl-3-phenylisoxazol-4- yl)phenyl)sulphonylpropylamid und sein natriumsalz als pro-pharmakon von cox-2 inhibitoren |
| DE69729946T2 (de) * | 1996-10-15 | 2005-01-20 | G.D. Searle Llc | Verwendung von cyclooxygenase-2 inhibitoren zur behandlung und verbeugung von neoplasia |
| PE20021017A1 (es) * | 2001-04-03 | 2002-11-24 | Pharmacia Corp | Composicion parenteral reconstituible |
| IL161086A0 (en) * | 2001-10-02 | 2004-08-31 | Pharmacia Corp | Method for preparing benzenesulfonyl compounds |
-
2003
- 2003-03-12 NZ NZ535951A patent/NZ535951A/en unknown
- 2003-03-12 KR KR1020047014454A patent/KR100763045B1/ko not_active Expired - Fee Related
- 2003-03-12 MX MXPA04008932A patent/MXPA04008932A/es unknown
- 2003-03-12 IL IL16378003A patent/IL163780A0/xx unknown
- 2003-03-12 PL PL03372880A patent/PL372880A1/xx not_active Application Discontinuation
- 2003-03-12 EP EP03716476A patent/EP1485362A1/en not_active Withdrawn
- 2003-03-12 US US10/387,173 patent/US20030232871A1/en not_active Abandoned
- 2003-03-12 CA CA002478500A patent/CA2478500A1/en not_active Abandoned
- 2003-03-12 BR BR0308431-0A patent/BR0308431A/pt not_active IP Right Cessation
- 2003-03-12 JP JP2003576414A patent/JP2005529084A/ja active Pending
- 2003-03-12 CN CNA038060884A patent/CN1642926A/zh active Pending
- 2003-03-12 WO PCT/US2003/007484 patent/WO2003078408A1/en not_active Ceased
- 2003-03-12 AU AU2003220180A patent/AU2003220180A1/en not_active Abandoned
- 2003-03-12 RU RU2004127585/04A patent/RU2300529C2/ru not_active IP Right Cessation
- 2003-03-14 AR ARP030100915A patent/AR038985A1/es unknown
- 2003-03-14 MY MYPI20030900A patent/MY148518A/en unknown
- 2003-03-14 TW TW092105693A patent/TW200400949A/zh unknown
-
2004
- 2004-09-10 CO CO04090186A patent/CO5631437A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2478500A1 (en) | 2003-09-25 |
| RU2300529C2 (ru) | 2007-06-10 |
| TW200400949A (en) | 2004-01-16 |
| CO5631437A2 (es) | 2006-04-28 |
| WO2003078408A1 (en) | 2003-09-25 |
| AR038985A1 (es) | 2005-02-02 |
| IL163780A0 (en) | 2005-12-18 |
| MY148518A (en) | 2013-04-30 |
| CN1642926A (zh) | 2005-07-20 |
| US20030232871A1 (en) | 2003-12-18 |
| KR20040095288A (ko) | 2004-11-12 |
| KR100763045B1 (ko) | 2007-10-04 |
| EP1485362A1 (en) | 2004-12-15 |
| JP2005529084A (ja) | 2005-09-29 |
| PL372880A1 (en) | 2005-08-08 |
| AU2003220180A1 (en) | 2003-09-29 |
| RU2004127585A (ru) | 2005-04-10 |
| NZ535951A (en) | 2006-02-24 |
| MXPA04008932A (es) | 2004-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A,8A E 9A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 7A, 8A E 9A ANUIDADES. |