BR0306901A - Tieno (3,2-b) piridonas como compostos antivirais - Google Patents

Tieno (3,2-b) piridonas como compostos antivirais

Info

Publication number
BR0306901A
BR0306901A BR0306901-0A BR0306901A BR0306901A BR 0306901 A BR0306901 A BR 0306901A BR 0306901 A BR0306901 A BR 0306901A BR 0306901 A BR0306901 A BR 0306901A
Authority
BR
Brazil
Prior art keywords
pyridones
compounds
thieno
antiviral compounds
salts
Prior art date
Application number
BR0306901-0A
Other languages
English (en)
Inventor
Scott D Larsen
Paul D May
Karen Romines
Mark E Schnute
Steven P Tanis
James A Neiman
David John Anderson
Euibong J Kim
Steven Ronald Turner
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BR0306901A publication Critical patent/BR0306901A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"TIENO (3,2-B) PIRIDONAS COMO COMPOSTOS ANTIVIRAIS". A invenção proporciona um composto da fórmula (I): (F) em que G, R^ 2^, R^ 3^ e R^ 4^ têm qualquer um dos valores definidos na especificação ou um sal farmaceuticamente aceitável do mesmo, bem como processos e intermediários úteis para o preparo de tais compostos ou sais e métodos de prevenção ou tratamento de uma infecção por herpesvírus usando-se tais compostos ou sais.
BR0306901-0A 2002-01-14 2003-01-14 Tieno (3,2-b) piridonas como compostos antivirais BR0306901A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34886602P 2002-01-14 2002-01-14
PCT/US2003/001025 WO2003059878A2 (en) 2002-01-14 2003-01-14 Thieno (3, 2-b) pyridones as antiviral compounds

Publications (1)

Publication Number Publication Date
BR0306901A true BR0306901A (pt) 2004-11-23

Family

ID=23369885

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0306901-0A BR0306901A (pt) 2002-01-14 2003-01-14 Tieno (3,2-b) piridonas como compostos antivirais

Country Status (10)

Country Link
US (1) US6852731B2 (pt)
EP (1) EP1472260A2 (pt)
JP (1) JP2005527489A (pt)
AR (1) AR038118A1 (pt)
AU (1) AU2003219661A1 (pt)
BR (1) BR0306901A (pt)
CA (1) CA2472960A1 (pt)
MX (1) MXPA04006857A (pt)
TW (1) TW200400965A (pt)
WO (1) WO2003059878A2 (pt)

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US20070010543A1 (en) * 2005-07-01 2007-01-11 Dynogen Pharmaceuticals, Inc. Compositions and methods for treating gastrointestinal hypomotility and associated disorders
CA2802641C (en) 2010-07-13 2019-03-12 Nidhi Arora Pyrazolo [1, 5a] pyrimidine and thieno [3, 2b] pyrimidine derivatives as irak4 modulators
RS60834B1 (sr) 2015-12-09 2020-10-30 Cadent Therapeutics Inc Modulatori heteroaromatskog nmda receptora i njihove upotrebe
US10973825B2 (en) 2015-12-09 2021-04-13 Cadent Therapeutics, Inc. Thienopyrimidinone NMDA receptor modulators and uses thereof
CN107337610A (zh) * 2016-11-15 2017-11-10 南京量子化工科技有限公司 新型beta‑肾上腺素受体激动剂通用半抗原的合成及应用
JP7332472B2 (ja) 2016-12-22 2023-08-23 ノバルティス アーゲー Ｎｍｄａ受容体モジュレーターおよびその使用
CN107628990B (zh) * 2017-11-10 2021-03-09 南京哈柏医药科技有限公司 5-溴吡啶-3-甲醛的合成方法
CN108218798B (zh) * 2017-12-13 2020-04-24 南方医科大学 Apabetalone的制备方法
SG11202101125VA (en) 2018-08-03 2021-03-30 Cadent Therapeutics Inc Heteroaromatic nmda receptor modulators and uses thereof
WO2020053654A1 (en) 2018-09-12 2020-03-19 Novartis Ag Antiviral pyridopyrazinedione compounds
CN113784962A (zh) 2019-02-27 2021-12-10 加利福尼亚大学董事会 用于治疗脑部疾病的氮杂环庚三烯并-吲哚类和其他杂环
JP7417715B2 (ja) 2019-09-26 2024-01-18 ノバルティス アーゲー 抗ウイルスピラゾロピリジノン化合物

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JPS5742690A (en) 1980-08-28 1982-03-10 Kanebo Ltd Thieno 3,2-b pyridinecarboxylic acid derivative
JPS57116077A (en) 1981-01-12 1982-07-19 Kanebo Ltd Thieno(3,2-b)pyridinecarboxylic acid derivative
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US4767766A (en) * 1987-01-30 1988-08-30 Merck & Co., Inc. Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors
IT1203323B (it) * 1987-02-02 1989-02-15 Hoechst Italia Spa Additivo fotoattivatore per composizioni polimeriche costituito dal sale metallico di una cera ossidata
US4959363A (en) * 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
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WO1992003427A1 (en) 1990-08-17 1992-03-05 Yoshitomi Pharmaceutical Industries, Ltd. Ketone compound and remedy for osteoporosis
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JP2699794B2 (ja) 1992-03-12 1998-01-19 三菱化学株式会社 チエノ〔３，２−ｂ〕ピリジン誘導体
DE4227747A1 (de) 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
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AU4515896A (en) 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
JPH08301849A (ja) 1995-05-01 1996-11-19 Takeda Chem Ind Ltd ヘテロ環化合物およびその製造法
JPH09208496A (ja) 1996-01-30 1997-08-12 Takeda Chem Ind Ltd Ｌｈ−ｒｈ拮抗物質含有組成物
CA2250908C (en) 1996-04-30 2012-03-13 Takeda Chemical Industries, Ltd. Combined use of gnrh agonist and antagonist
WO1998011073A1 (en) 1996-09-10 1998-03-19 Pharmacia & Upjohn Company 8-hydroxy-7-substituted quinolines as anti-viral agents
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Also Published As

Publication number Publication date
WO2003059878A2 (en) 2003-07-24
TW200400965A (en) 2004-01-16
JP2005527489A (ja) 2005-09-15
AR038118A1 (es) 2004-12-29
EP1472260A2 (en) 2004-11-03
WO2003059878A3 (en) 2003-12-04
MXPA04006857A (es) 2004-12-06
US20040242884A1 (en) 2004-12-02
CA2472960A1 (en) 2003-07-14
US6852731B2 (en) 2005-02-08
AU2003219661A1 (en) 2003-07-30
AU2003219661A8 (en) 2003-07-30

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Legal Events

Date Code Title Description
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]