BR0211557A - Compostos de 4-tioxo-4,7-dihidro-tieno[2,3-b]piridina-5-carbotioamid as como agentes antivirais, contosições e seus usos - Google Patents

Compostos de 4-tioxo-4,7-dihidro-tieno[2,3-b]piridina-5-carbotioamid as como agentes antivirais, contosições e seus usos

Info

Publication number
BR0211557A
BR0211557A BR0211557-3A BR0211557A BR0211557A BR 0211557 A BR0211557 A BR 0211557A BR 0211557 A BR0211557 A BR 0211557A BR 0211557 A BR0211557 A BR 0211557A
Authority
BR
Brazil
Prior art keywords
compounds
thioxo
dihydro
pyridine
carbothioamide
Prior art date
Application number
BR0211557-3A
Other languages
English (en)
Inventor
Atli Thorarensen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BR0211557A publication Critical patent/BR0211557A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSTOS DE 4-TIOXO-4,7-DIHIDRO-TIENO[2,3-b]PIRIDINA-5-CARBOTIOAMID AS COMO AGENTES ANTIVIRAIS, COMPOSIçõES E SEUS USOS". A invenção fornece um composto de fórmula I: onde R^ 1^, R^ 2^, R^ 3^ e R^ 4^ possuem qualquer um dos valores definidos na especificação, ou um sal farmaceuticamente aceitável deste, assim como processos e intermediários úteis para a preparação de tais compostos ou sais, e método de tratamento de uma infecção causada pelo vírus do herpes, aterosclerose ou restenose usando-se tais compostos ou sais.
BR0211557-3A 2001-08-30 2002-08-29 Compostos de 4-tioxo-4,7-dihidro-tieno[2,3-b]piridina-5-carbotioamid as como agentes antivirais, contosições e seus usos BR0211557A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31612901P 2001-08-30 2001-08-30
PCT/US2002/027738 WO2003020730A1 (en) 2001-08-30 2002-08-29 4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides as antiviral agents

Publications (1)

Publication Number Publication Date
BR0211557A true BR0211557A (pt) 2004-07-13

Family

ID=23227593

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211557-3A BR0211557A (pt) 2001-08-30 2002-08-29 Compostos de 4-tioxo-4,7-dihidro-tieno[2,3-b]piridina-5-carbotioamid as como agentes antivirais, contosições e seus usos

Country Status (7)

Country Link
US (1) US6924283B2 (pt)
EP (1) EP1421088A1 (pt)
JP (1) JP2005502686A (pt)
BR (1) BR0211557A (pt)
CA (1) CA2452438A1 (pt)
MX (1) MXPA04001798A (pt)
WO (2) WO2003020728A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
EP2445877B1 (en) * 2008-12-03 2014-07-23 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
WO2020053654A1 (en) 2018-09-12 2020-03-19 Novartis Ag Antiviral pyridopyrazinedione compounds
KR20220070005A (ko) 2019-09-26 2022-05-27 노파르티스 아게 항바이러스성 피라졸로피리디논 화합물

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WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS

Also Published As

Publication number Publication date
WO2003020730A1 (en) 2003-03-13
WO2003020728A1 (en) 2003-03-13
CA2452438A1 (en) 2003-03-13
US6924283B2 (en) 2005-08-02
EP1421088A1 (en) 2004-05-26
MXPA04001798A (es) 2004-07-08
JP2005502686A (ja) 2005-01-27
US20030100536A1 (en) 2003-05-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 5A., 6A. E 7A. ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.