BR0302074A - Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesma - Google Patents
Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesmaInfo
- Publication number
- BR0302074A BR0302074A BR0302074-6A BR0302074A BR0302074A BR 0302074 A BR0302074 A BR 0302074A BR 0302074 A BR0302074 A BR 0302074A BR 0302074 A BR0302074 A BR 0302074A
- Authority
- BR
- Brazil
- Prior art keywords
- laurate
- myristate
- porous bodies
- antibiotic
- netylmycin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Anesthesiology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
"REVESTIMENTO ANTIBIóTICO DE CORPOS POROSOS E PROCESSOS PARA PRODUçãO, BEM COMO USO DA MESMA". A invenção refere-se à descrição de um revestimento antibiótico de corpos porosos e uso do mesmo. No sistema de poros de corpos porosos não-metálicos e de corpos porosos metálicos, é inserido um revestimento de pelo menos um sal de antibiótico, pouco solúvel em água ou no meio aquoso, do grupo do laurato de netilmicina, do miristato de netilmicina, do dodecilsulfato de netilmicina, do laurato de sisomicina, do miristato de sisomicina, do dodecilsulfato de sisomicina, do laurato de gentamicina, do miristato de gentamicina, do laurato de clindamicina, do laurato da amicacina, do miristato de amicacina, do dodecilsulfato de amicacina, do laurato de canamicina, do miristato de canamicina, do dodecilsulfato de canamicina, do laurato de tobramicina, do miristato de tobramicina, do dodecilsulfato de tobramicina, do miristato de ciprofloxacina, do dodecilsulfato de vancomicina, do laurato de vancomicina, do miristato de vancomicina, da teicoplanina de vancomicina e da teicoplanina de clindamicina. Os corpos porosos revestidos antibioticamente são usados como implantes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10227935A DE10227935B4 (de) | 2002-06-21 | 2002-06-21 | Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0302074A true BR0302074A (pt) | 2004-04-27 |
Family
ID=29716605
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0302074-6A BR0302074A (pt) | 2002-06-21 | 2003-06-17 | Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesma |
BRPI0302074-6A BRPI0302074B1 (pt) | 2002-06-21 | 2003-06-17 | Corpos porosos compreendendo um revestimento antibiótico, seus processos para produção, bem como seus usos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0302074-6A BRPI0302074B1 (pt) | 2002-06-21 | 2003-06-17 | Corpos porosos compreendendo um revestimento antibiótico, seus processos para produção, bem como seus usos |
Country Status (12)
Country | Link |
---|---|
US (1) | US7030093B2 (pt) |
EP (1) | EP1374923B1 (pt) |
JP (1) | JP4838488B2 (pt) |
CN (1) | CN1310682C (pt) |
AT (1) | ATE337802T1 (pt) |
BR (2) | BR0302074A (pt) |
CA (1) | CA2431984C (pt) |
DE (3) | DE10227935B4 (pt) |
DK (1) | DK1374923T3 (pt) |
ES (1) | ES2268220T3 (pt) |
PT (1) | PT1374923E (pt) |
ZA (1) | ZA200304798B (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10318991A1 (de) * | 2003-04-25 | 2004-11-18 | Heraeus Kulzer Gmbh & Co. Kg | Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung |
DE102004021739B4 (de) * | 2004-04-30 | 2007-11-22 | Heraeus Kulzer Gmbh | Metallimplantat mit Oberflächenbeschichtung |
DE102004060666B3 (de) | 2004-12-15 | 2006-03-30 | Heraeus Kulzer Gmbh | Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung |
ES2387195T3 (es) | 2005-05-27 | 2012-09-17 | Royer Biomedical, Inc. | Matrices de polímero y métodos de fabricación y uso de las mismas |
DE102006007245A1 (de) * | 2006-02-15 | 2007-08-23 | Heraeus Kulzer Gmbh | Implantatmaterial |
US20070197548A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
US20070196398A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone fatty acid salt compositions |
DE102006016598A1 (de) * | 2006-04-06 | 2007-11-15 | Heraeus Kulzer Gmbh | Beschichtete Vaskulärimplantate |
CN100418978C (zh) * | 2006-11-01 | 2008-09-17 | 福州大学 | 一种采用膜分离技术制备西索米星的方法 |
DE102006060934A1 (de) * | 2006-12-20 | 2008-06-26 | Wolter, Dietmar F., Prof. Dr. | Saugdrainage mit einem antibakteriell wirkenden Materialdepot |
JP5131632B2 (ja) * | 2007-05-10 | 2013-01-30 | 国立大学法人 新潟大学 | 薬物徐放材料及びその製造方法 |
EP2018864A1 (en) | 2007-07-23 | 2009-01-28 | Biomet Deutschland GmbH | Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition |
US20090192609A1 (en) * | 2008-01-29 | 2009-07-30 | Zimmer, Inc. | Implant device for use in an implant system |
US7972615B2 (en) * | 2008-03-27 | 2011-07-05 | Affinergy, Inc. | Peptide compositions for coating metal medical devices with vancomycin |
DE102010020940B4 (de) | 2010-05-19 | 2014-09-25 | Heraeus Medical Gmbh | Antibiotische Beschichtung |
DE102010055560B4 (de) | 2010-12-23 | 2017-02-23 | Heraeus Medical Gmbh | Beschichtungsvorrichtung |
DE102010055561B4 (de) | 2010-12-23 | 2015-12-31 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung |
DE102010055559B4 (de) | 2010-12-23 | 2015-10-29 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung |
DE102010055562B4 (de) | 2010-12-23 | 2015-07-09 | Heraeus Medical Gmbh | Beschichtungsvorrichtung und Beschichtungsverfahren |
DE102011117526B4 (de) | 2011-11-03 | 2015-07-30 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung für medizinische Implantate |
US9492374B2 (en) | 2015-03-25 | 2016-11-15 | Jose Rafael Salinas Andrade | Composition and method for treatment of ulcers |
BR112020000196A2 (pt) | 2017-07-07 | 2020-07-07 | Epicentrx, Inc. | composições para administração parenteral de agentes terapêuticos |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3091572A (en) * | 1962-07-16 | 1963-05-28 | Schering Corp | Gentamycin and method of production |
CA950831A (en) | 1972-04-25 | 1974-07-09 | Leonard D. Kurtz | Biocidal salts |
FR2272680B1 (pt) | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
DE2807132C2 (de) | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
DE3206725A1 (de) * | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
DE3377064D1 (en) | 1982-12-28 | 1988-07-21 | Bayer Ag | Stable aminoglycoside-penicillin injection formulation |
DE3414924A1 (de) * | 1984-04-19 | 1985-10-31 | Klaus Dr.med. Dr.med.habil. 8000 München Draenert | Beschichtetes verankerungsteil fuer implantate |
US4749585A (en) * | 1986-04-11 | 1988-06-07 | University Of Medicine And Dentistry Of New Jersey | Antibiotic bonded prosthesis and process for producing same |
DE3613213A1 (de) * | 1986-04-18 | 1987-10-22 | Merck Patent Gmbh | Tricalciumphosphat fuer implantationsmaterialien |
DE4304716A1 (de) * | 1993-02-16 | 1994-08-18 | Melzer Wolfgang | Lokal applizierbares Arzneimittel mit verzögerter Freisetzung |
DE4314871A1 (de) * | 1993-05-05 | 1994-11-10 | Merck Patent Gmbh | Lösungsmittel für ein schwerlösliches Gentamicin-Salz |
JPH0767895A (ja) * | 1993-06-25 | 1995-03-14 | Sumitomo Electric Ind Ltd | 抗菌性人工血管及び抗菌性手術用縫合糸 |
DE4404018A1 (de) * | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
DE19726412A1 (de) * | 1997-06-21 | 1998-12-24 | Merck Patent Gmbh | Implantatmaterial mit einer Träger-Wirkstoff-Kombination |
EP0985413A1 (de) * | 1998-08-06 | 2000-03-15 | Jörg Michael Dr. Dr. Schierholz | Medizinprodukte mit retardierter pharmakologischer Aktivität und Verfahren zu ihrer Herstellung |
DE19855421C2 (de) * | 1998-11-02 | 2001-09-20 | Alcove Surfaces Gmbh | Implantat |
DE10114364A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
DE10114245A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
IS6390A (is) * | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra |
-
2002
- 2002-06-21 DE DE10227935A patent/DE10227935B4/de not_active Expired - Fee Related
- 2002-06-21 DE DE10262176A patent/DE10262176B4/de not_active Expired - Fee Related
-
2003
- 2003-05-28 EP EP03011967A patent/EP1374923B1/de not_active Expired - Lifetime
- 2003-05-28 DK DK03011967T patent/DK1374923T3/da active
- 2003-05-28 DE DE50304820T patent/DE50304820D1/de not_active Expired - Lifetime
- 2003-05-28 AT AT03011967T patent/ATE337802T1/de active
- 2003-05-28 PT PT03011967T patent/PT1374923E/pt unknown
- 2003-05-28 ES ES03011967T patent/ES2268220T3/es not_active Expired - Lifetime
- 2003-06-12 CA CA002431984A patent/CA2431984C/en not_active Expired - Fee Related
- 2003-06-17 BR BR0302074-6A patent/BR0302074A/pt not_active IP Right Cessation
- 2003-06-17 BR BRPI0302074-6A patent/BRPI0302074B1/pt unknown
- 2003-06-20 ZA ZA200304798A patent/ZA200304798B/xx unknown
- 2003-06-20 JP JP2003177000A patent/JP4838488B2/ja not_active Expired - Fee Related
- 2003-06-20 US US10/600,548 patent/US7030093B2/en not_active Expired - Lifetime
- 2003-06-23 CN CNB031486231A patent/CN1310682C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE50304820D1 (de) | 2006-10-12 |
US20040048786A1 (en) | 2004-03-11 |
EP1374923A2 (de) | 2004-01-02 |
JP4838488B2 (ja) | 2011-12-14 |
EP1374923B1 (de) | 2006-08-30 |
DK1374923T3 (da) | 2006-12-27 |
US7030093B2 (en) | 2006-04-18 |
CN1480226A (zh) | 2004-03-10 |
DE10227935B4 (de) | 2007-10-04 |
ATE337802T1 (de) | 2006-09-15 |
CN1310682C (zh) | 2007-04-18 |
CA2431984A1 (en) | 2003-12-21 |
DE10227935A1 (de) | 2004-01-15 |
JP2004067679A (ja) | 2004-03-04 |
CA2431984C (en) | 2009-09-08 |
BRPI0302074B1 (pt) | 2018-02-14 |
PT1374923E (pt) | 2006-11-30 |
ZA200304798B (en) | 2004-04-29 |
DE10262176B4 (de) | 2007-10-04 |
ES2268220T3 (es) | 2007-03-16 |
AU2003204863A1 (en) | 2004-01-15 |
EP1374923A3 (de) | 2004-02-11 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B25D | Requested change of name of applicant approved |
Owner name: HERAEUS KULZER GMBH (DE) |
|
B25A | Requested transfer of rights approved |
Owner name: HERAEUS MEDICAL GMBH (DE) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2624 DE 20-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |