CY1108043T1 - Πορωδη σωματα με αντιβιοτικη επικαλυψη, μεθοδος παραγωγης και χρηση - Google Patents

Πορωδη σωματα με αντιβιοτικη επικαλυψη, μεθοδος παραγωγης και χρηση

Info

Publication number
CY1108043T1
CY1108043T1 CY20081100073T CY081100073T CY1108043T1 CY 1108043 T1 CY1108043 T1 CY 1108043T1 CY 20081100073 T CY20081100073 T CY 20081100073T CY 081100073 T CY081100073 T CY 081100073T CY 1108043 T1 CY1108043 T1 CY 1108043T1
Authority
CY
Cyprus
Prior art keywords
production method
pore system
antibiotic
coating
antibiotic coating
Prior art date
Application number
CY20081100073T
Other languages
English (en)
Inventor
Sebastian Dr Vogt
Matthias Dr Schnabelrauch
Klaus-Dieter Dr KÜHN
Original Assignee
Heraeus Kulzer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer Gmbh filed Critical Heraeus Kulzer Gmbh
Publication of CY1108043T1 publication Critical patent/CY1108043T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Περιγράφεται ένα πορώδες σώμα με αντιβιοτική επικάλυψη, η παραγωγή και η χρήση. Στο πορώδες σύστημα μη μεταλλικών πορωδών σωμάτων και μεταλλικών πορωδών σωμάτων εισάγεται μια επικάλυψη από τουλάχιστον ένα λίγο διαλυτό στο νερό ή σε υδατικό περιβάλλον άλας αντιβιοτικού από την ομάδα του φουσιδικού οξέος-γενταμυκίνης, του φουσιδικού οξέος-σισομυκίνης, του φουσιδικού οξέος-νετιλμικίνης, του φουσιδικού οξέος-στρεπτομυκίνης, του φουσιδικού οξέος-τομπραμυκίνης, του φουσιδικού οξέος-σπεκτινομυκίνης, του φουσιδικού οξέος-βανκομυκίνης, του φουσιδικού οξέος-σιπροφλοξασίνης, του φουσιδικού οξέος-μοξιφλοξασίνης, του φουσιδικού οξέος-κλινδαμυκίνης, του φουσιδικού οξέος-λινκομυκινης, του φουσιδικού οξέος-τετρακυκλινης, του φουσιδικού οξέος-χλωροτετρακυκλινης, του φουσιδικού οξέος-οξυτετρακυκλινης και του φουσιδικού οξέος-ρολιτετρακυκλίνης. Τα επικαλυμμένα με αντιβιοτικά πορώδη σώματα χρησιμοποιούνται ως εμφυτεύματα.
CY20081100073T 2003-04-25 2008-01-18 Πορωδη σωματα με αντιβιοτικη επικαλυψη, μεθοδος παραγωγης και χρηση CY1108043T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10318991A DE10318991A1 (de) 2003-04-25 2003-04-25 Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
EP04007897A EP1470829B1 (de) 2003-04-25 2004-04-01 Peröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung

Publications (1)

Publication Number Publication Date
CY1108043T1 true CY1108043T1 (el) 2013-09-04

Family

ID=32946448

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100073T CY1108043T1 (el) 2003-04-25 2008-01-18 Πορωδη σωματα με αντιβιοτικη επικαλυψη, μεθοδος παραγωγης και χρηση

Country Status (16)

Country Link
US (1) US20050031664A1 (el)
EP (1) EP1470829B1 (el)
JP (1) JP2004321804A (el)
CN (1) CN1569257A (el)
AT (1) ATE378077T1 (el)
AU (1) AU2004200955B2 (el)
BR (1) BRPI0401467A (el)
CA (1) CA2459619C (el)
CY (1) CY1108043T1 (el)
DE (2) DE10318991A1 (el)
DK (1) DK1470829T3 (el)
ES (1) ES2294388T3 (el)
PL (1) PL1470829T3 (el)
PT (1) PT1470829E (el)
SI (1) SI1470829T1 (el)
ZA (1) ZA200403113B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007502861A (ja) * 2003-05-01 2007-02-15 レプリダイン・インコーポレーテッド 抗菌方法及び組成物
DE102006016598A1 (de) * 2006-04-06 2007-11-15 Heraeus Kulzer Gmbh Beschichtete Vaskulärimplantate
DE102007039871A1 (de) * 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
DE102010020940B4 (de) 2010-05-19 2014-09-25 Heraeus Medical Gmbh Antibiotische Beschichtung
DE102010055561B4 (de) 2010-12-23 2015-12-31 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung
DE102010055559B4 (de) 2010-12-23 2015-10-29 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung
DE102010055562B4 (de) 2010-12-23 2015-07-09 Heraeus Medical Gmbh Beschichtungsvorrichtung und Beschichtungsverfahren
DE102010055560B4 (de) 2010-12-23 2017-02-23 Heraeus Medical Gmbh Beschichtungsvorrichtung
DE102011117526B4 (de) 2011-11-03 2015-07-30 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung für medizinische Implantate

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3091572A (en) * 1962-07-16 1963-05-28 Schering Corp Gentamycin and method of production
FR1468638A (fr) * 1963-10-22 1967-02-10 Roussel Uclaf Sels de l'acide fusidique et procédé de préparation
DE2442021A1 (de) * 1974-09-03 1976-03-18 Bayer Ag Verfahren zur herstellung poroeser koerper auf der basis von gips, insbesondere anhydrit
US4291031A (en) * 1979-02-19 1981-09-22 Fujisawa Pharmaceutical Co., Ltd. 3-Phosphonocephalosporanic acid derivatives, and pharmaceutical composition comprising the same
GB2093348B (en) * 1981-02-23 1984-09-12 Leo Pharm Prod Ltd Pharmaceutical composition for implantation
DE3206725A1 (de) * 1981-05-13 1982-12-02 Merck Patent Gmbh, 6100 Darmstadt Schwer loesliche salze von aminoglykosidantibiotika
DE4314871A1 (de) * 1993-05-05 1994-11-10 Merck Patent Gmbh Lösungsmittel für ein schwerlösliches Gentamicin-Salz
DE19856668A1 (de) * 1998-12-09 2000-06-15 Aesculap Ag & Co Kg Wirkstoffmatrix in Form eines biologisch resorbierbaren porösen Vlieses, Verfahren zu ihrer Herstellung und Verwendung
DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
DE10114364A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Verfahren zur Herstellung von antibiotischen Kompositen
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
DE10227935B4 (de) * 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung

Also Published As

Publication number Publication date
PL1470829T3 (pl) 2008-06-30
BRPI0401467A (pt) 2005-01-18
DK1470829T3 (da) 2008-01-21
CN1569257A (zh) 2005-01-26
AU2004200955B2 (en) 2007-05-24
EP1470829B1 (de) 2007-11-14
EP1470829A1 (de) 2004-10-27
SI1470829T1 (sl) 2008-04-30
ES2294388T3 (es) 2008-04-01
JP2004321804A (ja) 2004-11-18
ZA200403113B (en) 2004-11-05
CA2459619C (en) 2008-08-12
US20050031664A1 (en) 2005-02-10
ATE378077T1 (de) 2007-11-15
AU2004200955A1 (en) 2004-11-11
DE10318991A1 (de) 2004-11-18
CA2459619A1 (en) 2004-10-25
DE502004005462D1 (de) 2007-12-27
PT1470829E (pt) 2007-12-26

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