BR0215452A - Teste de proteìna tirosina-fosfatase (ptpase) altamente sensitivo com o emprego de 6,8-diflúor-4-metil-umbeliferilfosfato - Google Patents

Teste de proteìna tirosina-fosfatase (ptpase) altamente sensitivo com o emprego de 6,8-diflúor-4-metil-umbeliferilfosfato

Info

Publication number
BR0215452A
BR0215452A BR0215452-8A BR0215452A BR0215452A BR 0215452 A BR0215452 A BR 0215452A BR 0215452 A BR0215452 A BR 0215452A BR 0215452 A BR0215452 A BR 0215452A
Authority
BR
Brazil
Prior art keywords
protein tyrosine
ptpase
difluoro
methyl
test
Prior art date
Application number
BR0215452-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Stefan Welte
Norbert Tennagels
Stefan Petry
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2002100173 external-priority patent/DE10200173A1/de
Priority claimed from DE2002136329 external-priority patent/DE10236329A1/de
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0215452A publication Critical patent/BR0215452A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR0215452-8A 2002-01-04 2002-12-24 Teste de proteìna tirosina-fosfatase (ptpase) altamente sensitivo com o emprego de 6,8-diflúor-4-metil-umbeliferilfosfato BR0215452A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2002100173 DE10200173A1 (de) 2002-01-04 2002-01-04 Ein hochsensitiver und kontinuerlicher Protein Tyrosin-Phosphatase (PTPase) Test unter Verwendung von 6,8 Difluoro-4-methyl-umbelliferylphosphat (DiFMUP)
DE2002136329 DE10236329A1 (de) 2002-08-08 2002-08-08 Ein hochsensitiver und kontinuierlicher Protein Tyrosin-Phosphatase (PTPase) Test unter Verwendung von 6,8 Difluoro-4-methyl-umbelliferylphosphat (DiFMUP)
EP0201475 2002-12-24

Publications (1)

Publication Number Publication Date
BR0215452A true BR0215452A (pt) 2004-11-23

Family

ID=26010898

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215452-8A BR0215452A (pt) 2002-01-04 2002-12-24 Teste de proteìna tirosina-fosfatase (ptpase) altamente sensitivo com o emprego de 6,8-diflúor-4-metil-umbeliferilfosfato

Country Status (12)

Country Link
EP (1) EP1466009A2 (de)
JP (1) JP2005512600A (de)
KR (1) KR20040073539A (de)
CN (1) CN1612939A (de)
AU (1) AU2002361217A1 (de)
BR (1) BR0215452A (de)
CA (1) CA2471601A1 (de)
IL (1) IL162832A0 (de)
MX (1) MXPA04006361A (de)
NO (1) NO20043244L (de)
RU (1) RU2004123794A (de)
WO (1) WO2003056029A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100350045C (zh) * 2003-08-21 2007-11-21 北京农业生物技术研究中心 玉米酪氨酸蛋白磷酸酶基因及其编码蛋白与应用
US8008035B2 (en) 2007-01-25 2011-08-30 Roche Diagnostics Operations, Inc. Enhancement of vanadium-containing phosphatase inhibitors
EP1949894B1 (de) * 2007-01-25 2016-06-29 Roche Diagnostics GmbH Verstärkung von vanadiumhaltigen Phosphatasehemmern mit Polyole
CN113155787A (zh) * 2020-12-29 2021-07-23 武汉合研生物医药科技有限公司 一种突变酶shp2 e76k的活性检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2331056A1 (en) * 1998-05-12 1999-12-02 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia

Also Published As

Publication number Publication date
JP2005512600A (ja) 2005-05-12
AU2002361217A1 (en) 2003-07-15
CN1612939A (zh) 2005-05-04
KR20040073539A (ko) 2004-08-19
CA2471601A1 (en) 2003-07-10
WO2003056029A2 (de) 2003-07-10
WO2003056029A3 (de) 2004-04-01
MXPA04006361A (es) 2004-10-04
EP1466009A2 (de) 2004-10-13
NO20043244L (no) 2004-08-02
RU2004123794A (ru) 2005-04-20
IL162832A0 (en) 2005-11-20

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]