BR0214233A - Método de detecção e/ou de quantificação, kit de reagentes e uso do método - Google Patents

Método de detecção e/ou de quantificação, kit de reagentes e uso do método

Info

Publication number
BR0214233A
BR0214233A BR0214233-3A BR0214233A BR0214233A BR 0214233 A BR0214233 A BR 0214233A BR 0214233 A BR0214233 A BR 0214233A BR 0214233 A BR0214233 A BR 0214233A
Authority
BR
Brazil
Prior art keywords
particles
magnetic field
magnetic
analyte
detection
Prior art date
Application number
BR0214233-3A
Other languages
English (en)
Inventor
Jean Baudry
Alain Rouseau
Jerome Bibette
Original Assignee
Stago Diagnostica
Jerome Bibette
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stago Diagnostica, Jerome Bibette filed Critical Stago Diagnostica
Publication of BR0214233A publication Critical patent/BR0214233A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

"MéTODO DE DETECçãO E/OU DE QUANTIFICAçãO, KIT DE REAGENTES E USO DO MéTODO". A presente invenção tem por objeto um método de detecção e/ou de quantificação de pelo menos um meio líquido, caracterizada pelo fato de utilizar partículas coloidais magnéticas funcionalizadas em superfície por pelo menos um ligante específico de um analito a ser detectado e/ou dosado e pelo fato de compreender: - a colocação em contato das referidas partículas com o referido meio a ser analisado, - a aplicação de um campo magnético ao referido meio, em uma intensidade suficiente para provocar a estruturação das referidas partículas magnéticas em forma de cadeias, - a manutenção desse campo magnético por um tempo suficiente para permitir o acoplamento ou a associação do analito considerado com pelo menos dois ligantes específicos presentes respectivamente em duas partículas vizinhas de uma cadeia, - a anulação do campo magnético, e - a determinação da presença e/ou ausência do referido analito e, se for o caso, de sua concentração através da presença ou da ausência de cadeia(s) permanente(s) de partículas magnéticas.
BR0214233-3A 2001-11-20 2002-11-20 Método de detecção e/ou de quantificação, kit de reagentes e uso do método BR0214233A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0115011A FR2832507B1 (fr) 2001-11-20 2001-11-20 Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales
PCT/FR2002/003974 WO2003044532A1 (fr) 2001-11-20 2002-11-20 Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales

Publications (1)

Publication Number Publication Date
BR0214233A true BR0214233A (pt) 2004-09-21

Family

ID=8869592

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214233-3A BR0214233A (pt) 2001-11-20 2002-11-20 Método de detecção e/ou de quantificação, kit de reagentes e uso do método

Country Status (19)

Country Link
US (1) US7332353B2 (pt)
EP (1) EP1446666B1 (pt)
JP (1) JP2005517899A (pt)
KR (1) KR20050044559A (pt)
CN (1) CN100501403C (pt)
AT (1) ATE431553T1 (pt)
AU (1) AU2002361324A1 (pt)
BR (1) BR0214233A (pt)
CA (1) CA2467050A1 (pt)
DE (1) DE60232353D1 (pt)
ES (1) ES2325917T3 (pt)
FR (1) FR2832507B1 (pt)
HU (1) HU225636B1 (pt)
MX (1) MXPA04004679A (pt)
NO (1) NO20042579L (pt)
PL (1) PL368690A1 (pt)
RU (1) RU2004118490A (pt)
WO (1) WO2003044532A1 (pt)
ZA (1) ZA200403903B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2878960A1 (fr) * 2004-12-08 2006-06-09 Centre Nat Rech Scient Procede pour mettre en oeuvre un test d'agglutination dans un microcanal
US9733315B2 (en) * 2005-07-27 2017-08-15 University Of Houston Nanomagnetic detector array for biomolecular recognition
CA2620861C (en) 2005-08-31 2016-07-05 T2 Biosystems, Inc. Nmr device for detection of analytes
US8586389B2 (en) * 2005-09-28 2013-11-19 Kent State University Ligand concentrating, liquid crystal biosensor system
WO2007085980A1 (en) 2006-01-25 2007-08-02 Koninklijke Philips Electronics N. V. Device for analyzing fluids
KR100738496B1 (ko) * 2006-07-27 2007-07-11 한양대학교 산학협력단 자성 미세입자 및 배향성 고정화 리간드를 이용한 항체단백질 분리방법
US8368402B2 (en) * 2006-11-08 2013-02-05 T2 Biosystems, Inc. NMR systems for in vivo detection of analytes
KR100823684B1 (ko) * 2006-12-06 2008-04-21 한국전자통신연구원 바코드 ｄｎａ를 이용한 생물학적 표적 물질의 검출 방법
FR2919390B1 (fr) 2007-07-27 2009-10-30 Bertin Technologies Soc Par Ac Procede de dosage d'un analyte dans un milieu liquide
AU2008325088A1 (en) * 2007-11-06 2009-05-14 T2 Biosystems, Inc. Small magnet and RF coil for magnetic resonance relaxometry
US20100323457A1 (en) * 2007-12-03 2010-12-23 Tokyo Institute Of Technology Biosensing method using coated magnetic fine particles and biosensing apparatus for biosensing method
FR2928656B1 (fr) * 2008-03-14 2011-08-26 Biomerieux Sa Procede de detection en temps reel de microorganismes dans un milieu de culture liquide par agglutination.
CA2741550C (en) 2008-10-29 2018-12-04 T2 Biosystems, Inc. Nmr detection of coagulation time
EP2492665A1 (en) * 2009-10-19 2012-08-29 Tokyo Institute of Technology Biosensor using magnetic microparticles
US9023607B2 (en) * 2010-04-26 2015-05-05 Intellectual Discovery Co., Ltd. Method for early diagnosis of alzheimer'S disease using phototransistor
FR2959820B1 (fr) * 2010-05-10 2013-03-15 Bertin Technologies Sa Procede de dosage d'un analyte dans un milieu liquide
CA3155334A1 (en) 2010-10-22 2012-04-26 T2 Biosystems, Inc. NMR SYSTEMS AND METHODS FOR RAPID ANALYTE DETECTION
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
EP2541250A1 (en) 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Molecular architecture on magnetic particles for affinity assays with low non-specific binding
WO2013010080A1 (en) 2011-07-13 2013-01-17 T2 Biosystems, Inc. Nmr methods for monitoring blood clot formation
US10620205B2 (en) 2011-09-21 2020-04-14 T2 Biosystems, Inc. NMR methods for endotoxin analysis
DE102011089798B4 (de) 2011-12-23 2021-06-10 Biophysical Tools GmbH Massiv paralleler Test molekularer Wechselwirkungen basierend auf magnetischen Nano- und Mikropartikeln
FR2986617B1 (fr) 2012-02-02 2015-03-27 Horiba Abx Sas Dispositif et procede pour effectuer des mesures hematologiques et biochimiques a partir d'un echantillon biologique
EP2839038B1 (en) 2012-04-20 2019-01-16 T2 Biosystems, Inc. Compositions and methods for detection of candida species
EP2929047A4 (en) 2012-12-07 2016-08-03 T2 Biosystems Inc METHOD FOR MONITORING THE FORMING OF SEALED GERINNSELN
CN108697141A (zh) * 2015-12-29 2018-10-23 N·V·努特里奇亚 含有不可消化寡糖和非复制型产乳酸细菌的营养配方物
AU2017210033B2 (en) 2016-01-21 2022-09-29 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
US11585882B2 (en) * 2018-04-11 2023-02-21 Mars Sciences Limited Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays
JP7264998B2 (ja) * 2018-05-30 2023-04-25 セプマグ、システムズ、ソシエダッド、リミターダ 生物学的及び化学的物質を検出するための光磁気泳動法
EP3824484A1 (en) * 2018-07-19 2021-05-26 Beckman Coulter Inc. Magnetic particles
EP4305198A1 (en) 2021-03-09 2024-01-17 Etablissement Français du Sang Detection of infectious agent based on recombinase polymerase amplification combined with a magnetic field-enhanced agglutination

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK140815B (da) * 1975-06-10 1979-11-19 Weeke Bengt Fremgangsmåde til påvisning eller bestemmelse af antistoffer i legemsvæsker ved hjælp af kendte antigener eller til bestemmelse af antigener ved hjælp af kendte antistoffer fra legemsvæsker samt et middel til anvendelse ved udøvelse af fremgangsmåden.
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4622298A (en) * 1984-08-09 1986-11-11 Becton, Dickinson And Company Detection and quantitation of microorganisms, leukocytes and squamous epithelial cells in urine
US5512332A (en) * 1985-10-04 1996-04-30 Immunivest Corporation Process of making resuspendable coated magnetic particles
US5639620A (en) * 1990-10-31 1997-06-17 Coulter Corporation Polymeric particles having a biodegradable gelatin or aminodextran coating and process for making same
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
WO1994009368A1 (en) * 1992-10-15 1994-04-28 Coulter Corporation Particles having gelatin-aminodextran coatings of and processes for making same
US5298741A (en) * 1993-01-13 1994-03-29 Trustees Of Tufts College Thin film fiber optic sensor array and apparatus for concurrent viewing and chemical sensing of a sample
GB9524393D0 (en) * 1995-11-29 1996-01-31 Mini Agriculture & Fisheries Extraction and labelling of materials
JP2001503859A (ja) * 1996-10-15 2001-03-21 バイオ―テック・イメイジング・インコーポレイテッド Ｈｉｖ感染細胞の検出試薬系およびそのためのキット
US5817458A (en) * 1996-10-15 1998-10-06 The Avriel Group, Amcas Division Inc. Reagent system for detecting HIV-infected peripheral blood lymphocytes in whole blood
WO1998051435A1 (en) * 1997-05-14 1998-11-19 Weixin Tang Fully-coated, uniform-sized metallic particles
WO1999033559A1 (en) * 1997-12-24 1999-07-08 Cepheid Integrated fluid manipulation cartridge
DE19822123C2 (de) * 1997-11-21 2003-02-06 Meinhard Knoll Verfahren und Vorrichtung zum Nachweis von Analyten
ATE239801T1 (de) * 1998-01-22 2003-05-15 Luminex Corp Mikropartikel mit multiplen fluoreszenz-signalen

Also Published As

Publication number Publication date
RU2004118490A (ru) 2005-04-20
ES2325917T3 (es) 2009-09-24
WO2003044532A1 (fr) 2003-05-30
EP1446666B1 (fr) 2009-05-13
EP1446666A1 (fr) 2004-08-18
ATE431553T1 (de) 2009-05-15
FR2832507B1 (fr) 2004-02-20
MXPA04004679A (es) 2005-05-17
DE60232353D1 (de) 2009-06-25
KR20050044559A (ko) 2005-05-12
AU2002361324A1 (en) 2003-06-10
US7332353B2 (en) 2008-02-19
HUP0402276A2 (hu) 2005-02-28
CA2467050A1 (fr) 2003-05-30
CN1589405A (zh) 2005-03-02
FR2832507A1 (fr) 2003-05-23
US20050048673A1 (en) 2005-03-03
ZA200403903B (en) 2005-06-23
CN100501403C (zh) 2009-06-17
JP2005517899A (ja) 2005-06-16
HU225636B1 (en) 2007-05-02
NO20042579L (no) 2004-06-18
HUP0402276A3 (en) 2005-11-28
PL368690A1 (en) 2005-04-04

Similar Documents

Publication Publication Date Title
BR0214233A (pt) Método de detecção e/ou de quantificação, kit de reagentes e uso do método
ATE306670T1 (de) Elektrochemischer immunoassay mit kolloidalem metall
WO2007011936A3 (en) Lateral flow assay and device using magnetic particles
BR9710836A (pt) Ensaio de analitos usando marcas em partìculas
WO2005065387A3 (en) Waveguide comprising scattered light detectable particles
DK1086372T3 (da) Opsamlingsindretning til enkelttrinsanalyse af mundvæsker
WO2001075450A3 (en) Fluorescent lifetime assays for non-invasive quantification of analytes
SG169395A1 (en) Detection of cancer by elevated levels of bcl-2
WO2006134546A3 (en) Accurate magnetic biosensor
WO2004113914A8 (en) System and method for coding information on a biosensor test strip
WO2003042396A3 (en) Electronic detection of biological molecules using thin layers
DE69522831D1 (de) Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie
WO2003106964A3 (en) HIGH EFFICIENCY METHODS AND DEVICES FOR ASSAYING ANALYTES IN A FLUID SAMPLE
DE60323672D1 (de) Verringerung des hook-effektes in vorrichtungen zur durchführung von membran-basierten testverfahren
ATE274699T1 (de) Analytassay-vorrichtung mit vorabsorbieren-zone
PT1173770E (pt) Metodo para estimar o risco de ulcera peptica
Vantasin et al. Naked eye colorimetric quantification of protein content in milk using starch-stabilized gold nanoparticles
ATE274188T1 (de) Verfahren zur bestimmung eines analyten und kit dafür
WO2008067008A3 (en) A method for the quantitative evaluation of sex hormones in a serum sample
WO2004077057A8 (en) Standard for immunohistochemistry, immunocytochemistry and molecular cytogenetics
WO2003019194A3 (de) Verdrängungsassay zur detektion von ligat-ligand assoziationsereignissen
PL351672A1 (en) A method of detecting and/or quantifying a specific ige antibody in a liquid sample
WO2002017975A8 (en) Method and device for detecting ozone consuming agents
CA2466503A1 (en) Total cysteine assay
DE602004017881D1 (de) Blut- und urintest

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010.