HUP0402276A2 - Eljárás analit(ok) detektálására kolloid mágneses részecskék segítségével - Google Patents

Eljárás analit(ok) detektálására kolloid mágneses részecskék segítségével

Info

Publication number
HUP0402276A2
HUP0402276A2 HU0402276A HUP0402276A HUP0402276A2 HU P0402276 A2 HUP0402276 A2 HU P0402276A2 HU 0402276 A HU0402276 A HU 0402276A HU P0402276 A HUP0402276 A HU P0402276A HU P0402276 A2 HUP0402276 A2 HU P0402276A2
Authority
HU
Hungary
Prior art keywords
analyte
particles
magnetic
colloidal particles
magnetic field
Prior art date
Application number
HU0402276A
Other languages
English (en)
Inventor
Jérome Bibette
Jean Baudry
Alain Rousseau
Original Assignee
Diagnostica Stago
Jérome Bibette
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostica Stago, Jérome Bibette filed Critical Diagnostica Stago
Publication of HUP0402276A2 publication Critical patent/HUP0402276A2/hu
Publication of HUP0402276A3 publication Critical patent/HUP0402276A3/hu
Publication of HU225636B1 publication Critical patent/HU225636B1/hu

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/5434Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

A találmány tárgya eljárás legalább egy analit detektálására és/vagykvantitatív meghatározására egy folyékony közegben. A találmánylényege az, hogy olyan mágneses kolloid részecskéket alkalmaznak,amelyeket a felületükön egy detektálandó és/vagy mérendő analitlegalább egy specifikus liganduma által reakcióképessé tesznek, ésamely eljárás során ezeket a részecskéket érintkezésbe hozzák azanalizálandó közeggel, a közeget olyan intenzitású mágneses térhatásának teszik ki, ami elégséges a mágneses részecskék láncokformájában való szerveződésének kiváltására, ezt a mágneses teretfenntartják olyan időtartamra, ami elégséges az adott analitkapcsolódásának vagy asszociációjának létrejöttéhez legalább kétspecifikus ligandummal, amelyek egy lánc két egymást követő szomszédosrészecskéjén vannak jelen, megszüntetik a mágneses teret, ésmegállapítják az analit meglétét és/vagy hiányát, és adott esetbenannak koncentrációját is, a mágneses kolloid részecskék folytonosláncának (láncainak) a folyékony közegben való megléte vagy hiányaalapján. Ó
HU0402276A 2001-11-20 2002-11-20 Method for detecting analyte(s) in fluid HU225636B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0115011A FR2832507B1 (fr) 2001-11-20 2001-11-20 Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales
PCT/FR2002/003974 WO2003044532A1 (fr) 2001-11-20 2002-11-20 Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales

Publications (3)

Publication Number Publication Date
HUP0402276A2 true HUP0402276A2 (hu) 2005-02-28
HUP0402276A3 HUP0402276A3 (en) 2005-11-28
HU225636B1 HU225636B1 (en) 2007-05-02

Family

ID=8869592

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402276A HU225636B1 (en) 2001-11-20 2002-11-20 Method for detecting analyte(s) in fluid

Country Status (19)

Country Link
US (1) US7332353B2 (hu)
EP (1) EP1446666B1 (hu)
JP (1) JP2005517899A (hu)
KR (1) KR20050044559A (hu)
CN (1) CN100501403C (hu)
AT (1) ATE431553T1 (hu)
AU (1) AU2002361324A1 (hu)
BR (1) BR0214233A (hu)
CA (1) CA2467050A1 (hu)
DE (1) DE60232353D1 (hu)
ES (1) ES2325917T3 (hu)
FR (1) FR2832507B1 (hu)
HU (1) HU225636B1 (hu)
MX (1) MXPA04004679A (hu)
NO (1) NO20042579L (hu)
PL (1) PL368690A1 (hu)
RU (1) RU2004118490A (hu)
WO (1) WO2003044532A1 (hu)
ZA (1) ZA200403903B (hu)

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FR2919390B1 (fr) 2007-07-27 2009-10-30 Bertin Technologies Soc Par Ac Procede de dosage d'un analyte dans un milieu liquide
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FR2928656B1 (fr) * 2008-03-14 2011-08-26 Biomerieux Sa Procede de detection en temps reel de microorganismes dans un milieu de culture liquide par agglutination.
US9157974B2 (en) 2008-10-29 2015-10-13 T2 Biosystems, Inc. NMR detection of coagulation time
EP2492665A1 (en) * 2009-10-19 2012-08-29 Tokyo Institute of Technology Biosensor using magnetic microparticles
US9023607B2 (en) * 2010-04-26 2015-05-05 Intellectual Discovery Co., Ltd. Method for early diagnosis of alzheimer'S disease using phototransistor
FR2959820B1 (fr) * 2010-05-10 2013-03-15 Bertin Technologies Sa Procede de dosage d'un analyte dans un milieu liquide
WO2012054638A2 (en) 2010-10-22 2012-04-26 T2 Biosystems, Inc. Nmr systems and methods for the detection of analytes
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
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EP2541250A1 (en) 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Molecular architecture on magnetic particles for affinity assays with low non-specific binding
EP2732046B1 (en) 2011-07-13 2017-09-06 T2 Biosystems, Inc. Nmr methods for monitoring blood clot formation
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DE102011089798B4 (de) 2011-12-23 2021-06-10 Biophysical Tools GmbH Massiv paralleler Test molekularer Wechselwirkungen basierend auf magnetischen Nano- und Mikropartikeln
FR2986617B1 (fr) * 2012-02-02 2015-03-27 Horiba Abx Sas Dispositif et procede pour effectuer des mesures hematologiques et biochimiques a partir d'un echantillon biologique
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Also Published As

Publication number Publication date
KR20050044559A (ko) 2005-05-12
NO20042579L (no) 2004-06-18
WO2003044532A1 (fr) 2003-05-30
AU2002361324A1 (en) 2003-06-10
MXPA04004679A (es) 2005-05-17
FR2832507A1 (fr) 2003-05-23
EP1446666A1 (fr) 2004-08-18
BR0214233A (pt) 2004-09-21
HU225636B1 (en) 2007-05-02
RU2004118490A (ru) 2005-04-20
PL368690A1 (en) 2005-04-04
EP1446666B1 (fr) 2009-05-13
CN100501403C (zh) 2009-06-17
CA2467050A1 (fr) 2003-05-30
FR2832507B1 (fr) 2004-02-20
ZA200403903B (en) 2005-06-23
JP2005517899A (ja) 2005-06-16
US20050048673A1 (en) 2005-03-03
CN1589405A (zh) 2005-03-02
US7332353B2 (en) 2008-02-19
ES2325917T3 (es) 2009-09-24
DE60232353D1 (de) 2009-06-25
HUP0402276A3 (en) 2005-11-28
ATE431553T1 (de) 2009-05-15

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MM4A Lapse of definitive patent protection due to non-payment of fees