BR0211661A - Molécula de ácido nucléico isolada, polipeptìdeo, gene quimérico, célula hospedeira transformada, método de obtenção, produto, método de produção, método de regulação e gene mutado - Google Patents

Molécula de ácido nucléico isolada, polipeptìdeo, gene quimérico, célula hospedeira transformada, método de obtenção, produto, método de produção, método de regulação e gene mutado

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Publication number
BR0211661A
BR0211661A BR0211661-8A BR0211661A BR0211661A BR 0211661 A BR0211661 A BR 0211661A BR 0211661 A BR0211661 A BR 0211661A BR 0211661 A BR0211661 A BR 0211661A
Authority
BR
Brazil
Prior art keywords
gene
nucleic acid
host cell
acid molecule
isolated nucleic
Prior art date
Application number
BR0211661-8A
Other languages
English (en)
Inventor
David L Hallahan
Natalie M Keiper-Hrynko
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BR0211661A publication Critical patent/BR0211661A/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen

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  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"MOLéCULA DE áCIDO NUCLéICO ISOLADA, POLIPEPTìDEO, GENE QUIMéRICO, CéLULA HOSPEDEIRA TRANSFORMADA, MéTODO DE OBTENçãO, PRODUTO, MéTODO DE PRODUçãO, MéTODO DE REGULAçãO E GENE MUTADO". A presente invenção refere-se à bioprodução de difosfato de isopentenila no látex da seringueira, Hevea brasiliensis. A síntese de difosfato de isopentenila (IPP) a partir de acetato é mediada por um conjunto de enzimas codificadas por seis genes isolados na forma de cDNAs de marca de seq³ência expressa (EST) de látex de Hevea brasiliensis. Além disso, descobriu-se uma seq³ência variante de uma destas enzimas, Acetil-CoA acetiltransferase.
BR0211661-8A 2001-07-25 2002-07-23 Molécula de ácido nucléico isolada, polipeptìdeo, gene quimérico, célula hospedeira transformada, método de obtenção, produto, método de produção, método de regulação e gene mutado BR0211661A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30767301P 2001-07-25 2001-07-25
PCT/US2002/024048 WO2003010294A2 (en) 2001-07-25 2002-07-23 Genes involved in the biosynthesis of isopentenyl diphosphate in hevea brasiliensis latex

Publications (1)

Publication Number Publication Date
BR0211661A true BR0211661A (pt) 2005-05-03

Family

ID=23190733

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211661-8A BR0211661A (pt) 2001-07-25 2002-07-23 Molécula de ácido nucléico isolada, polipeptìdeo, gene quimérico, célula hospedeira transformada, método de obtenção, produto, método de produção, método de regulação e gene mutado

Country Status (9)

Country Link
US (1) US6998471B2 (pt)
EP (1) EP1434784A4 (pt)
JP (1) JP2005500840A (pt)
AU (1) AU2002355297A1 (pt)
BR (1) BR0211661A (pt)
CA (1) CA2451430A1 (pt)
HU (1) HUP0700092A2 (pt)
MX (1) MXPA04000645A (pt)
WO (1) WO2003010294A2 (pt)

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EP1641931B1 (en) * 2003-07-08 2008-11-19 DSM IP Assets B.V. Improved production of coenzyme q-10
CN102027124B (zh) 2007-12-13 2015-11-25 丹尼斯科美国公司 用于生产异戊二烯的组合物和方法
EP2279251A2 (en) 2008-04-23 2011-02-02 Danisco US Inc. Isoprene synthase variants for improved microbial production of isoprene
CN102083990B (zh) * 2008-07-04 2016-05-04 财富科学家股份有限公司 通过3-羟基烷酸的酶促脱羧制备烯
US8518686B2 (en) * 2009-04-23 2013-08-27 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
CN106119113A (zh) * 2009-04-30 2016-11-16 基因组股份公司 用于生产 1,3‑丁二醇的生物
TWI427149B (zh) * 2009-06-17 2014-02-21 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
CN109136161A (zh) * 2009-12-10 2019-01-04 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
KR101281068B1 (ko) * 2010-10-08 2013-07-09 한국생명공학연구원 파라고무나무 유래의 라텍스 분비 조직 특이적 ｓｒｐｐ 프로모터 및 이의 용도
CN103443271A (zh) 2010-10-27 2013-12-11 丹尼斯科美国公司 用于增加异戊二烯产量的异戊二烯合酶变体
BR112013016264A2 (pt) 2010-12-22 2018-06-19 Danisco Us Inc produção biológica de açúcares de pentose com o uso de células recombinantes
SG191235A1 (en) 2010-12-22 2013-07-31 Danisco Us Inc Compositions and methods for improved isoprene production using two types of ispg enzymes
MY169821A (en) * 2011-09-15 2019-05-16 Univ Sains Malaysia A method for regulating cytosolic isoprenoid biosynthesis in hevea brasiliensis
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
US9523097B2 (en) * 2013-03-15 2016-12-20 The United States Of America, As Represented By The Secretary Of Agriculture Engineering rubber production in plants
JP6448194B2 (ja) 2014-01-20 2019-01-09 住友ゴム工業株式会社 シス型プレニルトランスフェラーゼをコードする遺伝子、及び、ＮｏｇｏＢｒｅｃｅｐｔｏｒをコードする遺伝子を宿主に導入することにより、該宿主において、シス型プレニルトランスフェラーゼ及びＮｏｇｏＢｒｅｃｅｐｔｏｒを発現させた形質転換体、並びに該形質転換体を用いたポリイソプレノイドの製造方法
US10590395B2 (en) * 2014-05-23 2020-03-17 Osaka University Mutein, method for producing said mutein, gene encoding said mutein, recombinant vector and plant bearing said gene, method for controlling amount of mevalonic acid produced and amount of isoprenoid produced, method for controlling 3-hydroxy-3-methylglutaryl-CoA reductase activity
KR101658346B1 (ko) * 2014-09-25 2016-09-22 한국생명공학연구원 메탄올 또는 메틸로트로픽 박테리아 처리에 의한 식물체에서 고무 함량을 증가시키는 방법
US10480014B2 (en) * 2015-06-15 2019-11-19 Ajou University Industry-Academic Cooperation Foundation Method for producing natural rubber by using recombinant microorganism
JP6706813B2 (ja) 2015-06-30 2020-06-10 住友ゴム工業株式会社 膜結合蛋白質を結合させたゴム粒子の製造方法、空気入りタイヤの製造方法及びゴム製品の製造方法
CN107709565B (zh) 2015-06-30 2021-09-14 住友橡胶工业株式会社 聚类异戊二烯、载体、转基因植物的制造方法，充气轮胎的制造方法及橡胶制品的制造方法
JP6586693B2 (ja) 2015-06-30 2019-10-09 住友ゴム工業株式会社 ポリイソプレノイドの製造方法、形質転換植物、空気入りタイヤの製造方法及びゴム製品の製造方法
CN105886528B (zh) * 2016-01-28 2020-06-23 中国热带农业科学院橡胶研究所 一种用乳管特异性启动子获得橡胶树转基因植株的方法

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EP0955363A3 (en) 1998-05-06 2004-01-28 F. Hoffmann-La Roche Ag Dna sequences encoding enzymes involved in production of isoprenoids
EP1033405A3 (en) 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
AU3286500A (en) 1999-03-05 2000-09-28 Syngenta Participations Ag Herbicide target genes and methods
US6316695B1 (en) 1999-04-22 2001-11-13 Korea Kumho Petrochemical Co., Ltd. Isopentenyl diphosphate isomerase from Hevea brasiliensis and rubber producing method using the same
US6180607B1 (en) * 1999-08-05 2001-01-30 Christopher Davies Protein having proteinase inhibitor activity
US6319710B1 (en) * 1999-08-23 2001-11-20 Decode Genetics Ehf. Human narcolepsy gene
BR0014934A (pt) 1999-10-27 2002-06-18 Unilever Nv Usos de um gene que expressa uma hmg-redutase sem retro-inibição e de um gene heterólogo que expressa uma hmg-redutase sem retro-inibição truncada, método de obtenção de sementes, planta, tecido de planta, sementes, método de obtenção de óleo, e, produto alimentìcio

Also Published As

Publication number Publication date
WO2003010294A2 (en) 2003-02-06
CA2451430A1 (en) 2003-02-06
US6998471B2 (en) 2006-02-14
MXPA04000645A (es) 2004-03-26
HUP0700092A2 (en) 2007-05-02
US20030119098A1 (en) 2003-06-26
EP1434784A4 (en) 2005-06-29
JP2005500840A (ja) 2005-01-13
WO2003010294A3 (en) 2004-02-19
AU2002355297A1 (en) 2003-02-17
EP1434784A2 (en) 2004-07-07

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