BR0210835A - Moléculas de agrecanase - Google Patents

Moléculas de agrecanase

Info

Publication number
BR0210835A
BR0210835A BR0210835-6A BR0210835A BR0210835A BR 0210835 A BR0210835 A BR 0210835A BR 0210835 A BR0210835 A BR 0210835A BR 0210835 A BR0210835 A BR 0210835A
Authority
BR
Brazil
Prior art keywords
agrecanase
molecules
enzyme
agrecana
proteins
Prior art date
Application number
BR0210835-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Michael J Agostino
Elizabeth Di Blasio
Edward R Lavallie
Lisa A Racie
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BR0210835A publication Critical patent/BR0210835A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR0210835-6A 2001-07-05 2002-07-05 Moléculas de agrecanase BR0210835A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30305101P 2001-07-05 2001-07-05
US34913302P 2002-01-16 2002-01-16
PCT/US2002/021056 WO2003004607A2 (en) 2001-07-05 2002-07-05 Aggrecanase molecules

Publications (1)

Publication Number Publication Date
BR0210835A true BR0210835A (pt) 2004-07-13

Family

ID=26973233

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0210835-6A BR0210835A (pt) 2001-07-05 2002-07-05 Moléculas de agrecanase

Country Status (9)

Country Link
US (1) US20030148306A1 (enExample)
EP (1) EP1409658A4 (enExample)
JP (1) JP2004533841A (enExample)
BR (1) BR0210835A (enExample)
CA (1) CA2451374A1 (enExample)
MX (1) MXPA03011715A (enExample)
NZ (1) NZ530949A (enExample)
PL (1) PL367675A1 (enExample)
WO (1) WO2003004607A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7150983B2 (en) * 2002-02-05 2006-12-19 Wyeth Truncated aggrecanase molecules
CN1681920A (zh) * 2002-07-29 2005-10-12 惠氏公司 修饰的admts4分子及其使用方法
WO2005025611A1 (en) * 2003-09-16 2005-03-24 Pharmacia Corporation Inhibitors of pace4 for the treatment of arthritis
US20050277175A1 (en) * 2004-04-16 2005-12-15 Wyeth Truncated ADAMTS molecules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
CA2383592A1 (en) * 1999-03-31 2000-10-05 Curagen Corporation 2384891 acids including open reading frames encoding polypeptides; orfx
JP2001008687A (ja) * 1999-06-25 2001-01-16 Yamanouchi Pharmaceut Co Ltd 新規金属プロテアーゼ及び該金属プロテアーゼ遺伝子
EP1234042A1 (en) * 1999-10-25 2002-08-28 Millennium Pharmaceuticals, Inc. Protein 27875, a human adam-ts homolog
EP1134286A3 (en) * 2000-03-14 2003-05-02 Pfizer Products Inc. Adamts polypeptides, nucleic acids encoding them, and uses thereof

Also Published As

Publication number Publication date
NZ530949A (en) 2005-09-30
PL367675A1 (en) 2005-03-07
WO2003004607A3 (en) 2003-07-31
WO2003004607A2 (en) 2003-01-16
MXPA03011715A (es) 2004-03-19
JP2004533841A (ja) 2004-11-11
EP1409658A4 (en) 2006-08-23
EP1409658A2 (en) 2004-04-21
US20030148306A1 (en) 2003-08-07
CA2451374A1 (en) 2003-01-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.