BR0209081A - Processo de remoção de produto e sistema de remoção de produto in situ - Google Patents

Processo de remoção de produto e sistema de remoção de produto in situ

Info

Publication number
BR0209081A
BR0209081A BR0209081-3A BR0209081A BR0209081A BR 0209081 A BR0209081 A BR 0209081A BR 0209081 A BR0209081 A BR 0209081A BR 0209081 A BR0209081 A BR 0209081A
Authority
BR
Brazil
Prior art keywords
product removal
biofermentation
broth
situ
removal process
Prior art date
Application number
BR0209081-3A
Other languages
English (en)
Portuguese (pt)
Inventor
Antoinette E Wilkins
David J Lowe
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BR0209081A publication Critical patent/BR0209081A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/02—Percolation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR0209081-3A 2001-04-20 2002-04-22 Processo de remoção de produto e sistema de remoção de produto in situ BR0209081A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28555501P 2001-04-20 2001-04-20
PCT/US2002/012606 WO2002086135A2 (en) 2001-04-20 2002-04-22 A product removal process for use in a biofermentation system

Publications (1)

Publication Number Publication Date
BR0209081A true BR0209081A (pt) 2004-06-22

Family

ID=23094748

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209081-3A BR0209081A (pt) 2001-04-20 2002-04-22 Processo de remoção de produto e sistema de remoção de produto in situ

Country Status (10)

Country Link
US (2) US6812000B2 (https=)
EP (1) EP1379673A4 (https=)
JP (1) JP4261196B2 (https=)
KR (1) KR20040014500A (https=)
CN (1) CN1250733C (https=)
AU (1) AU2002252704A1 (https=)
BR (1) BR0209081A (https=)
CA (1) CA2441774A1 (https=)
MX (1) MXPA03009552A (https=)
WO (1) WO2002086135A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040104581A (ko) * 2002-04-22 2004-12-10 이 아이 듀폰 디 네모아 앤드 캄파니 유전공학용 프로모터 및 플라스미드 시스템
US7229554B2 (en) * 2002-09-25 2007-06-12 Novo Nordisk A/S Purification process comprising microfiltration at elevated temperatures
DK1546304T3 (da) * 2002-10-04 2013-08-05 Danisco Us Inc Forbedret produktion af bakteriestammer
KR101148255B1 (ko) * 2002-10-04 2012-08-08 다니스코 유에스 인크. 고수율을 갖는 1,3-프로판디올의 생물학적 제조 방법
US20080178581A1 (en) * 2007-01-19 2008-07-31 Juon Co., Ltd. Utilizing biomass
US8609385B2 (en) 2007-05-01 2013-12-17 Zuvachem, Inc. Methods for the direct conversion of carbon dioxide into a hydrocarbon using a metabolically engineered photosynthetic microorganism
EP2014760A1 (en) * 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
WO2009106835A2 (en) * 2008-02-28 2009-09-03 Green Biologics Limited Production process
US20100264094A1 (en) * 2009-04-16 2010-10-21 Kent Bioenergy Corporation Method of developing a rapidly settling algal floc
SI3199511T1 (sl) * 2009-06-04 2020-07-31 Genomatica, Inc. Proces separacije komponent fermentacijske brozge
US8658845B2 (en) 2012-05-23 2014-02-25 Orochem Technologies, Inc. Process and adsorbent for separating ethanol and associated oxygenates from a biofermentation system
US8704016B2 (en) 2012-05-23 2014-04-22 Orochem Technologies, Inc. SMB process for the purification of ethanol and butanediol with integrated regeneration
EP2976418B1 (en) 2013-03-19 2020-09-30 CMC Biologics A/S A method for producing a product (e.g. polypeptide) in a continuous cell culture fermentation process.
WO2016164748A1 (en) 2015-04-08 2016-10-13 Invista North America S.A.R.L. Materials and methods for the selective recovery of monovalent products from aqueous solutions using continuous ion exchange
US10265642B2 (en) 2015-04-10 2019-04-23 Invista North America S.A.R.L. Process for separation of diamines and/or omega-aminoacids from a feed fixture
US12090420B2 (en) 2018-09-18 2024-09-17 Inv Nylon Chemicals Americas, Llc Systems and methods for recovering amines and their derivatives from aqueous mixtures
CN115667489A (zh) * 2020-02-11 2023-01-31 阿贝拉实验室公司 集成甲醇合成和发酵系统
EP4124653A1 (en) 2021-07-27 2023-02-01 Sartorius Stedim Biotech GmbH Method for producing a bioproduct
AU2022325485A1 (en) * 2021-08-13 2024-03-21 Bluetech Aps Industrial method for isolating an analyte from a liquid mixture

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135853A (en) * 1983-07-22 1992-08-04 Rensselaer Polytechnic Institute Three compartment bioreactor and method of use
US4851573A (en) 1986-12-18 1989-07-25 Uop Separation of citric acid from fermentation broth with a weakly basic anionic exchange resin adsorbent
EP0361082A3 (de) 1988-09-01 1991-09-18 Henkel KGaA Fermentative Herstellung von 1,3-Propandiol
AU6355790A (en) * 1989-08-04 1991-03-11 Peter Grandics An integrated cell culture-protein purification system for the automated production and purification of cell culture products
JP3018449B2 (ja) * 1990-09-21 2000-03-13 味の素株式会社 アミノ酸の発酵方法およびその装置
IT1247995B (it) * 1991-06-06 1995-01-05 Himont Inc Processo per la produzione di soluzioni acquose di acido lattico purificate a partire da brodi di fermentazione.
FI96225C (fi) * 1993-01-26 1996-05-27 Cultor Oy Menetelmä melassin fraktioimiseksi
FI98791C (fi) * 1994-04-21 1997-08-25 Xyrofin Oy Menetelmä liuoksen fraktioimiseksi
US5795398A (en) * 1994-09-30 1998-08-18 Cultor Ltd. Fractionation method of sucrose-containing solutions
US6146534A (en) * 1996-08-19 2000-11-14 Reilly Industries, Inc. Thermally-managed separation and dewatering processes for recovering acid products
US6224776B1 (en) * 1996-05-24 2001-05-01 Cultor Corporation Method for fractionating a solution
FI962204A0 (fi) 1996-05-24 1996-05-24 Cultor Oy Foerfarande foer fraktionering av en loesning
DE29611336U1 (de) * 1996-06-28 1996-09-19 Gesellschaft für Biotechnologische Forschung mbH (GBF), 38124 Braunschweig Filtrationsvorrichtung
US6379554B1 (en) * 1997-01-29 2002-04-30 Amalgamated Research Inc. Method of displacement chromatography
US6106723A (en) * 1997-02-10 2000-08-22 Grandics; Peter Method for removing pyrogens from dialysate
US6114157A (en) 1998-09-25 2000-09-05 General Electric Company Method for increasing total production of 4-hydroxybenzoic acid by biofermentation
GB9826684D0 (en) 1998-12-04 1999-01-27 Alpharma As Process for the purification of compounds by means of simulated moving bed (smb) chromatography
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
US6603048B1 (en) 1999-10-05 2003-08-05 E. I. Du Pont De Nemours And Company Process to separate 1,3-propanediol or glycerol, or a mixture thereof from a biological mixture
US6995246B1 (en) * 2000-10-19 2006-02-07 Akzo Nobel N.V. Methods for removing suspended particles from soluble protein solutions
FI20010977A7 (fi) * 2001-05-09 2002-11-10 Danisco Sweeteners Oy Kromatografinen erotusmenetelmä
US6872314B2 (en) * 2003-08-29 2005-03-29 Eastman Chemical Company Dewatering process

Also Published As

Publication number Publication date
US20050208615A1 (en) 2005-09-22
CN1503846A (zh) 2004-06-09
US6812000B2 (en) 2004-11-02
US20030166040A1 (en) 2003-09-04
US7166460B2 (en) 2007-01-23
JP4261196B2 (ja) 2009-04-30
CN1250733C (zh) 2006-04-12
KR20040014500A (ko) 2004-02-14
WO2002086135A2 (en) 2002-10-31
HK1066568A1 (en) 2005-03-24
EP1379673A4 (en) 2006-02-15
EP1379673A2 (en) 2004-01-14
CA2441774A1 (en) 2002-10-31
JP2004524852A (ja) 2004-08-19
WO2002086135A3 (en) 2003-02-13
MXPA03009552A (es) 2004-02-12
AU2002252704A1 (en) 2002-11-05

Similar Documents

Publication Publication Date Title
BR0209081A (pt) Processo de remoção de produto e sistema de remoção de produto in situ
BR0313265A (pt) Compostos e respectivos processos de preparação, uso e formulações farmacêuticas e métodos de prevenção e/ou tratamento de distúrbios mediados por receptor mglur5 e de inbição da ativação de receptores mglu r5.
DK0677039T3 (da) Cyclobutanderivater som squalen-syntetase- og protein-farnesyltransferaseinhibitorer
ES2155477T3 (es) Purificacion cromatografica y procedimiento de separacion de acidos nucleicos.
BR9709368A (pt) Método para o fracionamento de uma solução por meio de um processo de leito móvel simulado cromatográfico
DE69401506D1 (de) Verfahren zur chromatografischer fraktionierung von fettsäuren und ihre derivaten
BR0010555A (pt) Inibidores de neuraminidases
BR9914696A (pt) Composto, processo para tratamento de distúrbio mediado por ciclo-oxigenase-2 em um indivìduo, e, composição farmacêutica
EP1390449A4 (en) Process for isomerization dewaxing of hydrocarbon streams
DK1142485T3 (da) Fremgangsmåde til forbedring af oplöseligheden af planteproteiner
BR9807349A (pt) Composto, processos para preparar um composto e para preparar 6-o-alquil eritromicina a.
BR0011033A (pt) Métodos de purificação de dna e dna purificado
PT1025067E (pt) Processo para a cristalizacao de compostos impedidos estereoquimicamente
BR0008625A (pt) Processo para tratamento de asma induzida por exercìcio
BR9909309A (pt) Processos para preparar ácido acrìlico e para preparar um acrilato ou uma mistura de dois ou mais do mesmo, e, uso de ácido acrìlico oligomérico ou de uma mistura de ácido acrìlico e ácido acrìlico oligomérico
SE8402861L (sv) Rening av biologiskt material
MA21922A1 (fr) Procede de purification d'acides aminomethylene-phosphoniques .
BR9707466A (pt) Processo para a recuperação de componentes de um material flotante a partir de um sistema de tratamento de águas servidas
AU3038989A (en) Method for removal of organic solvents from aqueous process streams
ATE509028T1 (de) Ionen-austausch-chromatographische trennung von glp-1 und verwandten peptiden
BR9712199A (pt) Processos para a separação e a recuperação de compostos, compreendendo pelo menos uma função de amina protonável contidos dentro de um meio lìquido, e, para a produção de monÈmero de poliamida.
ES2096795T3 (es) Procedimiento para la separacion de aminoacidos de soluciones acuosas.
DE69902816D1 (de) Synthese von heteropolysäuren
ES2184300T3 (es) Derivados de aminoacidos utiles para tratar el accidente vascular encefalico.
BR9909870A (pt) Pirrolidinas como inibidores de neuraminidases

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 9A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.