BR0208463A - Compostos farmaceuticamente ativos - Google Patents
Compostos farmaceuticamente ativosInfo
- Publication number
- BR0208463A BR0208463A BR0208463-5A BR0208463A BR0208463A BR 0208463 A BR0208463 A BR 0208463A BR 0208463 A BR0208463 A BR 0208463A BR 0208463 A BR0208463 A BR 0208463A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutically active
- active compounds
- compounds
- phosphodiesterases
- monophosphate
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 2
- MIKUYHXYGGJMLM-GIMIYPNGSA-N Crotonoside Natural products C1=NC2=C(N)NC(=O)N=C2N1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O MIKUYHXYGGJMLM-GIMIYPNGSA-N 0.000 abstract 1
- NYHBQMYGNKIUIF-UHFFFAOYSA-N D-guanosine Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(CO)C(O)C1O NYHBQMYGNKIUIF-UHFFFAOYSA-N 0.000 abstract 1
- 101100189582 Dictyostelium discoideum pdeD gene Proteins 0.000 abstract 1
- 101150098694 PDE5A gene Proteins 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 102100029175 cGMP-specific 3',5'-cyclic phosphodiesterase Human genes 0.000 abstract 1
- 238000009109 curative therapy Methods 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229940029575 guanosine Drugs 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0107751.0A GB0107751D0 (en) | 2001-03-28 | 2001-03-28 | Pharmaceutically active compounds |
| PCT/IB2002/000854 WO2002079203A1 (en) | 2001-03-28 | 2002-03-19 | Imidazo-triazine derivatives as pde 5 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0208463A true BR0208463A (pt) | 2004-03-02 |
Family
ID=9911744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0208463-5A BR0208463A (pt) | 2001-03-28 | 2002-03-19 | Compostos farmaceuticamente ativos |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1395589A1 (https=) |
| JP (1) | JP2004528320A (https=) |
| AU (1) | AU2002241211A1 (https=) |
| BR (1) | BR0208463A (https=) |
| CA (1) | CA2442329A1 (https=) |
| GB (1) | GB0107751D0 (https=) |
| MX (1) | MXPA03005990A (https=) |
| WO (1) | WO2002079203A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7456184B2 (en) | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
| CA2462200A1 (en) | 2001-08-10 | 2003-02-20 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
| US7354923B2 (en) | 2001-08-10 | 2008-04-08 | Palatin Technologies, Inc. | Piperazine melanocortin-specific compounds |
| DE10229778A1 (de) * | 2002-07-03 | 2004-01-29 | Bayer Ag | Neue Verwendung von Imidazotriazinonen |
| JP2006219374A (ja) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Ｐｄｅ７阻害作用を有するイミダゾトリアジノン誘導体 |
| DK1697371T3 (da) * | 2003-12-19 | 2007-09-17 | Bristol Myers Squibb Co | Azabicykliske heterocykliske forbindelser som cannabinoidreceptormodulatorer |
| TW200528455A (en) * | 2003-12-19 | 2005-09-01 | Bristol Myers Squibb Co | Azabicyclic heterocycles as cannabinoid receptor modulators |
| US7683060B2 (en) | 2006-08-07 | 2010-03-23 | Incyte Corporation | Triazolotriazines as kinase inhibitors |
| ME02372B (me) | 2006-11-22 | 2016-06-20 | Incyte Holdings Corp | Imidazotriazini i imidazopiramidini kao inhibitori kinaze |
| WO2009143211A2 (en) | 2008-05-21 | 2009-11-26 | Incyte Corporation | Salts of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same |
| EA025304B1 (ru) | 2010-02-03 | 2016-12-30 | Инсайт Холдингс Корпорейшн | ИМИДАЗО[1,2-b][1,2,4]ТРИАЗИНЫ В КАЧЕСТВЕ c-Met ИНГИБИТОРОВ |
| CN102372730B (zh) * | 2010-08-19 | 2014-03-26 | 山东轩竹医药科技有限公司 | 桥环取代的磷酸二酯酶抑制剂 |
| CN102382129B (zh) * | 2010-08-19 | 2014-02-26 | 山东轩竹医药科技有限公司 | 螺环取代的磷酸二酯酶抑制剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9114760D0 (en) * | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
| GB9311920D0 (en) * | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
| US6362178B1 (en) * | 1997-11-12 | 2002-03-26 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| US6503908B1 (en) * | 1999-10-11 | 2003-01-07 | Pfizer Inc | Pharmaceutically active compounds |
| DE10010067A1 (de) * | 2000-03-02 | 2001-09-06 | Bayer Ag | Neue Imidazotriazinone und ihre Verwendung |
-
2001
- 2001-03-28 GB GBGB0107751.0A patent/GB0107751D0/en not_active Ceased
-
2002
- 2002-03-19 BR BR0208463-5A patent/BR0208463A/pt not_active IP Right Cessation
- 2002-03-19 WO PCT/IB2002/000854 patent/WO2002079203A1/en not_active Ceased
- 2002-03-19 MX MXPA03005990A patent/MXPA03005990A/es unknown
- 2002-03-19 JP JP2002577827A patent/JP2004528320A/ja not_active Withdrawn
- 2002-03-19 CA CA002442329A patent/CA2442329A1/en not_active Abandoned
- 2002-03-19 EP EP02707056A patent/EP1395589A1/en not_active Withdrawn
- 2002-03-19 AU AU2002241211A patent/AU2002241211A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2442329A1 (en) | 2002-10-10 |
| GB0107751D0 (en) | 2001-05-16 |
| JP2004528320A (ja) | 2004-09-16 |
| AU2002241211A1 (en) | 2002-10-15 |
| MXPA03005990A (es) | 2005-02-14 |
| EP1395589A1 (en) | 2004-03-10 |
| WO2002079203A1 (en) | 2002-10-10 |
| WO2002079203A8 (en) | 2002-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0014695A (pt) | 5-(2-substituìdo-5-heterociclilsulfonilpirid-3-il)-dihi dropirazolo[4,3-d]pirimidin-7-onas como inibidoras de fosfodiesterase | |
| BR9905109A (pt) | "compostos farmaceuticamente ativos" | |
| GB0106661D0 (en) | Pharmaceutically active compounds | |
| BR0004786A (pt) | Compostos farmaceuticamente ativos | |
| BR9905877A (pt) | Inibidores de pirazolopirimidinona de cgmp pde5 para o tratamento da disfunção sexual. | |
| BR0004779A (pt) | Compostos farmaceuticamente ativos | |
| ATE250063T1 (de) | Pyrazolopyrimidinone, cgmp pde5 inhibitoren, zur behandlung von sexuellen funktionsstörungen | |
| BR0317891A (pt) | Tratamento de ferimentos de pele usando polienilfosfatidil colina e alcanolaminas | |
| BR0208463A (pt) | Compostos farmaceuticamente ativos | |
| ATE298238T1 (de) | Pyrazolo(4,3-d)pyrimidinon-verbindungen als cgmp pde-inhibitoren | |
| BR0115446A (pt) | Processos para tratamento de condições associadas a quinase p38 e compostos pirrolotriazina úteis como inibidores de quinase | |
| BRPI0409227B8 (pt) | "composto, composição farmacêutica, uso de um composto e processo para a preparação de um composto de fórmula (i)" | |
| TNSN03144A1 (en) | Pyrrolopyrimidines as protein kinase inhibitors | |
| DE50012571D1 (de) | Biotin enthaltende galenische formulierung | |
| BR0200843A (pt) | Compostos farmaceuticamente ativos | |
| AP2002002462A0 (en) | Pharmaceutically active compounds. | |
| WO2004037166A3 (en) | Therapeutic guanidines | |
| PE20030236A1 (es) | Derivados de bencimidazol 1-aril-2-n,s- u o-sustituidos, obtencion de medicamentos y preparados farmaceuticos que contienen estos derivados | |
| BRPI0415964A (pt) | uso de um composto, composto, formulação farmacêutica, e, processo para preparar um composto | |
| BRPI0512013A (pt) | composto, formulação farmacêutica, uso de um composto, método para profilaxia ou tratamento de uma arritmia, e, processo para preparação de um composto | |
| ECSP003706A (es) | Compuestos farmaceuticamente activos | |
| ATE301997T1 (de) | Antivirale therapie | |
| PE20030337A1 (es) | Indan-1-onas sustituidas en c2 y sus derivados, procedimiento para su preparacion y su utilizacion como medicamentos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADES |
|
| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2055 DE 25/05/2010. |