BR0208463A - Compostos farmaceuticamente ativos - Google Patents
Compostos farmaceuticamente ativosInfo
- Publication number
- BR0208463A BR0208463A BR0208463-5A BR0208463A BR0208463A BR 0208463 A BR0208463 A BR 0208463A BR 0208463 A BR0208463 A BR 0208463A BR 0208463 A BR0208463 A BR 0208463A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutically active
- active compounds
- compounds
- phosphodiesterases
- monophosphate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"COMPOSTOS FARMACEUTICAMENTE ATIVOS". A presente invenção refere-se a compostos de fórmula geral (I): em que R^ 1^, R^ 2^, R^ 3^. R^ 4^, X, Y e A têm os significados dados aqui que são úteis no tratamento curativo e profilático de uma condição médica para a qual é desejada a inibição de 3^ '^,5^ '^-monofosfato cíclico de guanosina fosfodiesterases (por exemplo cGMp PDE5).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0107751.0A GB0107751D0 (en) | 2001-03-28 | 2001-03-28 | Pharmaceutically active compounds |
PCT/IB2002/000854 WO2002079203A1 (en) | 2001-03-28 | 2002-03-19 | Imidazo-triazine derivatives as pde 5 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0208463A true BR0208463A (pt) | 2004-03-02 |
Family
ID=9911744
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0208463-5A BR0208463A (pt) | 2001-03-28 | 2002-03-19 | Compostos farmaceuticamente ativos |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1395589A1 (pt) |
JP (1) | JP2004528320A (pt) |
AU (1) | AU2002241211A1 (pt) |
BR (1) | BR0208463A (pt) |
CA (1) | CA2442329A1 (pt) |
GB (1) | GB0107751D0 (pt) |
MX (1) | MXPA03005990A (pt) |
WO (1) | WO2002079203A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002331064B2 (en) | 2001-08-10 | 2007-08-23 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
DE10229778A1 (de) * | 2002-07-03 | 2004-01-29 | Bayer Ag | Neue Verwendung von Imidazotriazinonen |
JP2006219374A (ja) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Pde7阻害作用を有するイミダゾトリアジノン誘導体 |
TW200528455A (en) * | 2003-12-19 | 2005-09-01 | Bristol Myers Squibb Co | Azabicyclic heterocycles as cannabinoid receptor modulators |
DK1697371T3 (da) * | 2003-12-19 | 2007-09-17 | Bristol Myers Squibb Co | Azabicykliske heterocykliske forbindelser som cannabinoidreceptormodulatorer |
US7683060B2 (en) | 2006-08-07 | 2010-03-23 | Incyte Corporation | Triazolotriazines as kinase inhibitors |
LT3034075T (lt) | 2006-11-22 | 2018-11-26 | Incyte Holdings Corporation | Imidazotriazinai ir imidazopirimidinai kaip kinazės inhibitoriai |
NZ589622A (en) | 2008-05-21 | 2012-10-26 | Incyte Corp | Salts of 2-fluoro-N-methyl-4-[7-(quinolin-6-yl-methyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same |
AU2011269788B2 (en) | 2010-02-03 | 2015-12-10 | Incyte Holdings Corporation | Imidazo[1,2-b][1,2,4]triazines as c-Met inhibitors |
CN102372730B (zh) * | 2010-08-19 | 2014-03-26 | 山东轩竹医药科技有限公司 | 桥环取代的磷酸二酯酶抑制剂 |
CN102382129B (zh) * | 2010-08-19 | 2014-02-26 | 山东轩竹医药科技有限公司 | 螺环取代的磷酸二酯酶抑制剂 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9114760D0 (en) * | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
GB9311920D0 (en) * | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
PT1049695E (pt) * | 1997-11-12 | 2002-07-31 | Bayer Ag | Imidazotriazinonas 2-fenil substituidas enquanto inibidores de fosfodiesterase |
US6503908B1 (en) * | 1999-10-11 | 2003-01-07 | Pfizer Inc | Pharmaceutically active compounds |
DE10010067A1 (de) * | 2000-03-02 | 2001-09-06 | Bayer Ag | Neue Imidazotriazinone und ihre Verwendung |
-
2001
- 2001-03-28 GB GBGB0107751.0A patent/GB0107751D0/en not_active Ceased
-
2002
- 2002-03-19 WO PCT/IB2002/000854 patent/WO2002079203A1/en not_active Application Discontinuation
- 2002-03-19 MX MXPA03005990A patent/MXPA03005990A/es unknown
- 2002-03-19 BR BR0208463-5A patent/BR0208463A/pt not_active IP Right Cessation
- 2002-03-19 EP EP02707056A patent/EP1395589A1/en not_active Withdrawn
- 2002-03-19 AU AU2002241211A patent/AU2002241211A1/en not_active Abandoned
- 2002-03-19 JP JP2002577827A patent/JP2004528320A/ja not_active Withdrawn
- 2002-03-19 CA CA002442329A patent/CA2442329A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MXPA03005990A (es) | 2005-02-14 |
JP2004528320A (ja) | 2004-09-16 |
WO2002079203A8 (en) | 2002-11-21 |
AU2002241211A1 (en) | 2002-10-15 |
GB0107751D0 (en) | 2001-05-16 |
EP1395589A1 (en) | 2004-03-10 |
CA2442329A1 (en) | 2002-10-10 |
WO2002079203A1 (en) | 2002-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADES |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2055 DE 25/05/2010. |