BR0206967A - Procedimento de preparação de compostos derivados de tiazolidinediona, de oxazolidinediona - Google Patents

Procedimento de preparação de compostos derivados de tiazolidinediona, de oxazolidinediona

Info

Publication number
BR0206967A
BR0206967A BR0206967-9A BR0206967A BR0206967A BR 0206967 A BR0206967 A BR 0206967A BR 0206967 A BR0206967 A BR 0206967A BR 0206967 A BR0206967 A BR 0206967A
Authority
BR
Brazil
Prior art keywords
formula
compound
alkyl
procedure
atom
Prior art date
Application number
BR0206967-9A
Other languages
English (en)
Inventor
Michel Bullliard
Yvon Derrien
Tony Pintus
Original Assignee
Ppg Sipsy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0102010A external-priority patent/FR2820741A1/fr
Application filed by Ppg Sipsy filed Critical Ppg Sipsy
Publication of BR0206967A publication Critical patent/BR0206967A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/96Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCEDIMENTO DE PREPARAçãO DE COMPOSTOS DERIVADOS DE TIAZOLIDINEDIONA, DE OXAZOLIDINEDIONA". A presente invenção tem por objeto um procedimento de preparação de um composto derivado de tiazolidinediona, de oxazolidinediona ou de hidantónio de fórmula (I) a partir de um composto de fórmula (II) como se segue: (I) onde Q representa um átomo de oxigênio, um átomo de enxofre, Q1 representa um átomo de oxigênio ou um átomo de enxofre, R1 e R2, idênticos ou diferentes, representam um átomo de hidrogênio, uma cadeia alquila em C~ 1-10~: um cicloalquila, um alquilarila, um arilalquila; os ditos grupamentos alquilas, cicloaquila, alquilarila ou arilalquila sendo eventualmente substituídos por um alquila, um alquoxi ou ariloxi, um halogênio, um hidroxi, um sulfino, um sulfonila, um amino tal como NH2, NHR~ 3-~ N(R~ 3~)2, com R3 representando um alquila, um alquoxi ou um alquilcarbonila, caracterizado por se fazer reagir um composto de fórmula (II) com ácido fórmico em presença de um catalisador à base de um metal de transição, para obter o composto de fórmula (I) correspondente.
BR0206967-9A 2001-02-14 2002-02-14 Procedimento de preparação de compostos derivados de tiazolidinediona, de oxazolidinediona BR0206967A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0102010A FR2820741A1 (fr) 2001-02-14 2001-02-14 Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
FR0105206A FR2820742B1 (fr) 2001-02-14 2001-04-17 Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
PCT/FR2002/000571 WO2002064577A2 (fr) 2001-02-14 2002-02-14 Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione

Publications (1)

Publication Number Publication Date
BR0206967A true BR0206967A (pt) 2004-03-09

Family

ID=26212876

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206967-9A BR0206967A (pt) 2001-02-14 2002-02-14 Procedimento de preparação de compostos derivados de tiazolidinediona, de oxazolidinediona

Country Status (13)

Country Link
US (1) US6849741B2 (pt)
EP (1) EP1360179A2 (pt)
JP (1) JP2004520401A (pt)
KR (1) KR100856140B1 (pt)
CN (1) CN1491218A (pt)
AU (1) AU2002238645A1 (pt)
BR (1) BR0206967A (pt)
CA (1) CA2438105A1 (pt)
FR (1) FR2820742B1 (pt)
IL (1) IL157101A0 (pt)
MX (1) MXPA03007263A (pt)
RU (1) RU2003127720A (pt)
WO (1) WO2002064577A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6992191B2 (en) * 2001-12-20 2006-01-31 Teva Pharmaceutical Industries, Ltd. Hydrogenation of precursors to thiazolidinedione antihyperglycemics
CZ297347B6 (cs) * 2004-09-21 2006-11-15 Zentiva, A. S. Zpusob prípravy rosiglitazonu
EP1903042A3 (en) * 2006-09-22 2008-05-28 Cadila Pharmaceuticals Limited An improved process for hydrogenation of 5-(substituted Benzylidene) 2,4- Thiazolidine Dione compounds to give corresponding ( +/- ) 5- (substituted Benzyl ) 2,4-Thiazolidine Dione

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
DE69132713D1 (de) * 1990-04-27 2001-10-11 Sankyo Co Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren
AU3231093A (en) * 1991-12-20 1993-07-28 Upjohn Company, The A reduction method for substituted 5-methylene-thiazolidinediones
JP3163361B2 (ja) * 1992-03-12 2001-05-08 味の素株式会社 5−アルキルヒダントイン誘導体の製造法
US5399632A (en) * 1992-09-30 1995-03-21 Exxon Research & Engineering Co. Hydrogenation process for unsaturated homo and copolymers
JPH06199808A (ja) * 1993-01-04 1994-07-19 Ajinomoto Co Inc 5−シクロヘキシルメチルヒダントイン誘導体の製造方法およびその製造中間体
JPH08277279A (ja) * 1995-04-05 1996-10-22 Nitto Chem Ind Co Ltd ベンジルチアゾリジンジオン誘導体の製造方法
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
UY24886A1 (es) * 1997-02-18 2001-08-27 Smithkline Beecham Plc Tiazolidindiona
DE19711616A1 (de) * 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
JP4084501B2 (ja) * 1999-07-01 2008-04-30 三井化学株式会社 α−メルカプトカルボン酸およびその製造方法

Also Published As

Publication number Publication date
WO2002064577A3 (fr) 2003-01-03
US20040059121A1 (en) 2004-03-25
AU2002238645A1 (en) 2002-08-28
EP1360179A2 (fr) 2003-11-12
RU2003127720A (ru) 2005-03-20
CN1491218A (zh) 2004-04-21
IL157101A0 (en) 2004-02-08
FR2820742B1 (fr) 2005-03-11
US6849741B2 (en) 2005-02-01
JP2004520401A (ja) 2004-07-08
CA2438105A1 (fr) 2002-08-22
FR2820742A1 (fr) 2002-08-16
MXPA03007263A (es) 2005-02-14
KR100856140B1 (ko) 2008-09-03
WO2002064577A2 (fr) 2002-08-22
KR20030082594A (ko) 2003-10-22

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2025 DE 27/10/2009.