BR0113737A - Receptor do domìnio da edbfibronectina (11) - Google Patents

Receptor do domìnio da edbfibronectina (11)

Info

Publication number
BR0113737A
BR0113737A BR0113737-9A BR0113737A BR0113737A BR 0113737 A BR0113737 A BR 0113737A BR 0113737 A BR0113737 A BR 0113737A BR 0113737 A BR0113737 A BR 0113737A
Authority
BR
Brazil
Prior art keywords
edbfibronectin
domain
domain receptor
fibronectin
protein
Prior art date
Application number
BR0113737-9A
Other languages
English (en)
Inventor
Alexander REDLITZ
Marcus Koppitz
Ursula Egner
Inke Bahr
Andreas Menrad
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10045803A external-priority patent/DE10045803A1/de
Priority claimed from DE2001123133 external-priority patent/DE10123133A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of BR0113737A publication Critical patent/BR0113737A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Abstract

"RECEPTOR DO DOMìNIO DA ED~ b~FIBRONECTINA (II)". A invenção refere-se a uma proteína, que se liga especificamente ao domínio de ED~ b~fibronectina, processo para monitoramento de compostos que se ligam a um receptor do domínio ED~ b~fibronectina ou ele próprio ao domínio ED~ b~fibronectina, assim como aos empregos da proteína.
BR0113737-9A 2000-09-07 2001-08-30 Receptor do domìnio da edbfibronectina (11) BR0113737A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10045803A DE10045803A1 (de) 2000-09-07 2000-09-07 Rezeptor der EDb Fibronektin-Domäne
DE2001123133 DE10123133A1 (de) 2001-05-02 2001-05-02 Rezeptor der ED¶b¶-Fibronektin-Domäne (II)
PCT/EP2001/010016 WO2002020563A2 (de) 2000-09-07 2001-08-30 REZEPTOR DER EDb-FIBRONEKTIN-DOMÄNE (II)

Publications (1)

Publication Number Publication Date
BR0113737A true BR0113737A (pt) 2004-02-25

Family

ID=26007070

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113737-9A BR0113737A (pt) 2000-09-07 2001-08-30 Receptor do domìnio da edbfibronectina (11)

Country Status (24)

Country Link
US (3) US20020197700A1 (pt)
EP (1) EP1381629B1 (pt)
JP (1) JP2004529848A (pt)
KR (1) KR20030045056A (pt)
CN (1) CN1246333C (pt)
AT (1) ATE407951T1 (pt)
AU (1) AU1218202A (pt)
BG (1) BG107614A (pt)
BR (1) BR0113737A (pt)
CA (1) CA2421783A1 (pt)
DE (1) DE50114321D1 (pt)
EE (1) EE200300092A (pt)
ES (1) ES2312478T3 (pt)
HK (1) HK1064683A1 (pt)
HR (1) HRP20030263A2 (pt)
HU (1) HUP0300935A3 (pt)
IL (1) IL154778A0 (pt)
NO (1) NO20031033L (pt)
NZ (1) NZ524342A (pt)
PL (1) PL364358A1 (pt)
RU (1) RU2280254C2 (pt)
SK (1) SK2882003A3 (pt)
WO (1) WO2002020563A2 (pt)
YU (1) YU17503A (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003524018A (ja) 2000-02-24 2003-08-12 アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ フィブロネクチンのｅｄ‐ｂドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
WO2007054120A1 (de) 2005-11-09 2007-05-18 Bayer Schering Pharma Aktiengesellschaft Identifizierung und charakterisierung von funktionsblockierenden anti-ed-b-fibronektin antikörpern
EP1892248A1 (en) * 2006-08-21 2008-02-27 Eidgenössische Technische Hochschule Zürich Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase
JP5221641B2 (ja) 2007-04-02 2013-06-26 フィロゲン エスピーエー 腫瘍転移の血管新生と関連するフィブロネクチンのｅｄ−ａ抗原
US10202442B2 (en) 2007-07-25 2019-02-12 Philogen S.P.A. Antigen associated with lung cancers and lymphomas
EP3783019A1 (en) 2007-10-30 2021-02-24 Philogen S.p.A. An antigen associated with rheumatoid arthritis
EP2085095B1 (en) * 2008-01-17 2012-03-07 Philogen S.p.A. Combination of an anti-EDb fibronectin antibody-IL-2 fusion protein, and a molecule binding to B cells, B cell progenitors and/or their cancerous counterpart
WO2011015333A2 (en) 2009-08-05 2011-02-10 Philogen S.P.A. Targeting of bone marrow neovasculature
WO2014055073A1 (en) 2012-10-03 2014-04-10 Philogen S.P.A. Antigens associated with inflammatory bowel disease
CN111148759B (zh) * 2017-09-30 2023-09-19 合肥立方制药股份有限公司 结合至纤维连接蛋白b结构域的蛋白

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Also Published As

Publication number Publication date
DE50114321D1 (de) 2008-10-23
AU1218202A (en) 2002-03-22
BG107614A (bg) 2003-12-31
PL364358A1 (en) 2004-12-13
NZ524342A (en) 2005-09-30
ATE407951T1 (de) 2008-09-15
RU2003109431A (ru) 2005-01-20
KR20030045056A (ko) 2003-06-09
ES2312478T3 (es) 2009-03-01
YU17503A (sh) 2006-05-25
CN1246333C (zh) 2006-03-22
HRP20030263A2 (en) 2005-10-31
WO2002020563A3 (de) 2003-10-09
NO20031033L (no) 2003-05-07
NO20031033D0 (no) 2003-03-06
US20020197700A1 (en) 2002-12-26
RU2280254C2 (ru) 2006-07-20
EP1381629B1 (de) 2008-09-10
SK2882003A3 (en) 2003-08-05
HUP0300935A2 (hu) 2003-12-29
HK1064683A1 (en) 2005-02-04
CA2421783A1 (en) 2002-03-14
EE200300092A (et) 2005-06-15
EP1381629A2 (de) 2004-01-21
US20050221434A1 (en) 2005-10-06
HUP0300935A3 (en) 2005-09-28
CN1487953A (zh) 2004-04-07
IL154778A0 (en) 2003-10-31
US20050089941A1 (en) 2005-04-28
WO2002020563A2 (de) 2002-03-14
JP2004529848A (ja) 2004-09-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.